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Cisco Secure Email vs Trend Micro InterScan Messaging Security comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email
Ranking in Email Security
3rd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
62
Ranking in other categories
Cisco Security Portfolio (7th)
Trend Micro InterScan Messa...
Ranking in Email Security
34th
Average Rating
7.0
Reviews Sentiment
7.1
Number of Reviews
3
Ranking in other categories
Secure Email Gateway (SEG) (14th)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email is 6.4%, down from 8.6% compared to the previous year. The mindshare of Trend Micro InterScan Messaging Security is 0.7%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Kostas Karidas - PeerSpot reviewer
Helps prevent security breaches but fails to improve in the area of AI
I have not noticed any impressive advanced threat protection mechanisms in the tool. I don't know if there are any AI features in the product. I don't know if there is any other technology embedded in the solution. Cisco Secure Email successfully mitigated potential email threats. My company has seen plenty of scenarios where Cisco Secure Email successfully mitigated potential email threats, spam emails, and fraudulent domains. The product is good for dealing with spam emails, and it can take care of more than 100 spam emails per day. A huge number of spam emails are monitored with the help of Cisco Secure Email. I would not recommend the product to other businesses because you need to have some kind of expertise in configuring and knowing a bit about the tool's GUI. The tool also lacks in the area of AI mechanics. If I would like to have an overview and review another solution, I would go for another product other than Cisco Secure Email. I can definitely suggest others to look at the product and review it, but I would also recommend that they compare it with the other solutions in the market. I wouldn't prioritize Cisco Secure Email over other tools. Either the support partner of the product or I take care of the tool's maintenance phase by looking into the configurations and doing some fine-tuning. I rate the tool a seven to eight out of ten.
Abdul  Waris - PeerSpot reviewer
Deploy features like DLP and BEC for enhanced security
Multiple clients are using email security. We provide solutions based on what they need, and we configure them accordingly as per the requirement With Trend Micro email security gateway, we can deploy features like DLP and BEC. It includes Office 365 protection and sandboxing. This provides…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Since we have started using the solution, there have been fewer compromises."
"Microsoft Defender for Office 365's most valuable feature is its performance."
"The stability of Microsoft Defender for Office 365 is fantastic."
"Scalability-wise, I do not think there are any issues so far."
"Microsoft Defender for Office 365 is a stable solution."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"It's a bit easy to handle Cisco Secure Email; it's not that difficult. For the logs, which are in PDF format, it's not hard to read them. We don't need Wireshark much to analyze the logs."
"The product's initial setup phase was easy."
"It provided a platform to sell a service to customers."
"It is a user-friendly product."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive. Previously, our users had to deal with nine million additional emails across the organization, which is nearly 1,000 emails per user to have to deal with a month. That's a massive amount for our staff to deal with and probably several hours of their time. We have a lot of clinical staff, being a hospital. We want to make our staff as productive as possible. By removing a lot of that spam and phishing type emails, this allows them to do their job."
"ATP has been the most valuable in improving our email security posture."
"It has the IMS engine, Intelligent Multi-Scan engine, and it does a good job, right out-of-the-box, of blocking the vast majority of things that should be blocked."
"It is doing its work. It is doing what it was actually designed to do. It has ensured we don't have business email compromises, and it has also ensured that our brand Galaxy is unique all year round."
"The solution provides protection with its Email Track Records and Machine Manual features."
"The technical support services are excellent."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
 

Cons

"The visibility for the weaknesses in the system and unauthorized access can be improved."
"I'd like some additional features any product can give me to protect our environment in a better way."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"There is a different console for different things; I just want one consolidated console."
"The UI needs to be more user-friendly."
"Configuration at the mid-level could be improved for the support team."
"We need to be able to whitelist data at the backend."
"You should be able to deploy Defender for every subscription without the need to add servers."
"In future releases, I would like to see two main improvements come to mind. First, the current solution requires maintaining two separate operating systems for FTD, which can be cumbersome. I'd love to see a single operating system for the FTD box."
"Typically, in a phishing email, they try to use a name everybody's going to recognize, like the CEO's name or the CFO's name... With this appliance, the way it's designed at the moment, for us to really stop that with any level of confidence, we have to build a dictionary of all the names of the people we want it to check, and all the ways they could be spelled. My name would be in there as Phillip Collins, Phillip D. Collins, Phillip Dean Collins, Phil Collins, Phil D. Collins. There could be eight or 10 variations of my name that we'd have to put in the dictionary. There's no artificial intelligence to say "Phil Collins" could be all these other things, and to stop phishing from coming through in that way."
"I would like to see sandboxing for email, where suspicious emails received by the system are analyzed through online services."
"I would like them to add some clustering or high availability features."
"The tool's pricing can be improved."
"I have some frustrations with the user experience in the interface, specifically with regard to making a list of people for whom I want to allow email access."
"We cannot manage multiple devices from a single UI."
"The reporting functionality needs to be improved."
"The solution's pricing could be improved."
"The product's pricing could be more flexible."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
 

Pricing and Cost Advice

"The license is expensive because the cost is based on the number of users."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"You're going to get what you pay for. If you're not willing to pay the price of Cisco, you're not going to get a product that's as good as Cisco. I don't think Cisco is overpriced, because for the last two years I've been comparing it to Microsoft and Cisco has been cheaper and given us more features."
"As per market availability, this solution is more expensive than other vendors."
"Cisco Secure Email is expensive, but we get what we pay for."
"We were using Proofpoint and then we switched to Cisco... reportability was one of the main reasons we switched, but the biggest one was cost. If you can get an equivalent functionality for a better price it's wise to do so. That's what our primary decision came down to: We could get equivalent functionality at a lower price point."
"The price is significantly high."
"The pricing is good."
"The product's price falls on the higher side when compared to the other products on the market."
"Trend Micro is an expensive solution."
"I rate Trend Micro InterScan Messaging Security’s pricing a seven out of ten."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
19%
Educational Organization
19%
Financial Services Firm
9%
Manufacturing Company
6%
Manufacturing Company
11%
Computer Software Company
11%
Financial Services Firm
11%
Performing Arts
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The user interface of the Email Security Gateway ( /products/security-gateway-reviews ) should be improved. It would ...
What is your experience regarding pricing and costs for Trend Micro InterScan Messaging Security?
The price is a bit high because the market is highly competitive. Multiple platforms are available, so we have to cho...
What needs improvement with Trend Micro InterScan Messaging Security?
There is room for improvement in content filtration, expressions, file sharing, and policy configuration. We could de...
 

Also Known As

MS Defender for Office 365
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
InterScan Messaging Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Copa Airlines, Air21, BookMyShow, Bulgarian American Credit Bank, Canadian Museum of History, CIBIL, Community National Bank, Dar Al-Handasah
Find out what your peers are saying about Cisco Secure Email vs. Trend Micro InterScan Messaging Security and other solutions. Updated: June 2025.
858,469 professionals have used our research since 2012.