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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (20th), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of May 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.6% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.9%, down from 12.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.9%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other86.7%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The blocking feature is very good."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"It is a stable solution."
"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"I'm very satisfied with the environment and the dashboard."
"Cloudflare, in my opinion, was easy to implement."
"The solution is valuable if you are looking for a security email gateway that provides you with the most services possible."
"Overall, the ease of migration to Cisco's cloud email security from the on-prem solution was a positive experience."
"This solution provides some benefits, like comfortable access to TAC support. You get prompt support when working directly with Cisco."
"It does a great job of preventing spam, malware, and ransomware. I can only go by what people have told me and what I've seen, but I have not seen spam in a year and a half to two years in my own company mailbox. And there are not a lot of catches where it's catching something that should have gotten through, either."
"Anti-Spam and Advanced Malware Protection are the most valuable features... and we also have the option to block Zero-day attacks."
"Cisco Secure Email's most valuable is email certification."
"Capital expenditure is a significant consideration, and the impact on major expenditures prompts a careful analysis before onboarding the new product."
"We rely heavily on antivirus protection, email content filtering, and authentication mechanisms to ensure compliance with email security. Regarding phishing attempts, while phishing protection features are crucial, we also emphasize user education as a critical defence. The intelligence services Cisco provides, such as the Cisco Intelligence Center, play a significant role in analyzing and validating threats, including phishing attempts, in our email security practices."
"The most valuable feature of Microsoft Defender for Office 365 is data backups that we can provide through ticket requests."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"It also gives the vulnerability status according to the versions you have selected. Let's say you have Google Chrome. It mentions the versions it has, and it updates. Within two hours of an update, it is reflected in the dashboard. That's really nice to have."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"It’s easy to handle integrations, and we don't need a lot of people in our IT team."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"It has helped us in improving our security posture; it detects any kind of attack or abnormal behavior in accessing the system and sends an alert to the administrator who can check, understand, and review on time to ensure that all activities are legit."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
 

Cons

"I would like them to include a VPN feature to provide a secure connection to the data center."
"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"Operating and tuning the product is difficult."
"The initial onboarding was causing us some confusion."
"The initial onboarding was causing us some confusion."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"Feedback could be enhanced."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"We have been struggling in the last month with Cisco encryption and with the S/MIME encryption."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console."
"The reporting functionality needs to be improved."
"I would like more functionality and how to use it for Level 2 type staff."
"They can do it better with web links, with the URLs. They have a technology called Outbreak but it doesn't work as well as we would like."
"I would like to see sandboxing for email, where suspicious emails received by the system are analyzed through online services."
"Cisco Email Secure's pricing needs to be less. We have vendors who provide cheaper solutions with the same features."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"They can improve their security in a way where a customer can know if all their attachments are safe or not to open through a report. The solution does its job perfectly, but it never reports to the customer whether those attachments have been stopped before or not."
"Microsoft Defender for Office 365 should improve the troubleshooting tools. It's unclear whether the device is blocked at the firewall level or at the device itself. The granularity needed for troubleshooting is currently lacking. From my perspective, Microsoft should address this issue to benefit many users who likely share the same sentiment."
"Microsoft Defender for Office 365 is not up to the mark in comparison with Wiz or Palo Alto."
"There is room for improvement in terms of reporting."
"To improve Microsoft Defender for Office 365, it would be nice to have more accessibility for users to see on their end what they are doing that could cause a threat."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
 

Pricing and Cost Advice

"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The solution is not that expensive."
"The prices are slightly expensive."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution's pricing lacks transparency."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"Licensing costs depend on how many users there are. It could range between $5 and $7 per month, per user."
"At times, we feel the pricing is a bit too high, but then, there is also room for discounts. We enjoy a lot of discounts, and that is why we are still with them. There are no costs in addition to the standard licensing fees."
"The solution is expensive."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The product is very expensive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"I know that the product is incredibly expensive."
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Top Industries

By visitors reading reviews
Construction Company
20%
Comms Service Provider
11%
Financial Services Firm
8%
Manufacturing Company
6%
Financial Services Firm
11%
Computer Software Company
9%
Manufacturing Company
9%
Government
6%
Computer Software Company
12%
Financial Services Firm
9%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: April 2026.
893,244 professionals have used our research since 2012.