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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
4th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.5%, down from 6.4% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.3%
Cisco Secure Email4.5%
Cloudflare One1.6%
Other87.6%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"It is a stable solution."
"The blocking feature is very good."
"Cloudflare is simple to use."
"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."
"It will take the blow rather than our applications should an attack occur."
"Clover is the best product globally."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"We rely heavily on antivirus protection, email content filtering, and authentication mechanisms to ensure compliance with email security. Regarding phishing attempts, while phishing protection features are crucial, we also emphasize user education as a critical defence. The intelligence services Cisco provides, such as the Cisco Intelligence Center, play a significant role in analyzing and validating threats, including phishing attempts, in our email security practices."
"There are a lot of filters for scam emails and things like that work out of the box. You can also use the antivirus features. I like its features."
"The solution is valuable if you are looking for a security email gateway that provides you with the most services possible."
"It sends us reports, where we can see if there have been attacks, e.g. DDoS. If so, we can switch to a clean IP."
"The system enables end users to manage their own whitelists/blacklists."
"ATP has been the most valuable in improving our email security posture."
"We are now protected against spam emails."
"The tool comes with AI features. It is good for clients who already use Cisco products due to integration."
"The most valuable feature is the integration; it's a single console, so we don't have to switch around between multiple products, and another valuable feature is the ease of operations and maintenance."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"The insights provided with Microsoft Defender for Office 365 are helpful because it comes with the E5 license, and by default, we can use a lot of capabilities."
"I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection."
"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"It has helped us in improving our security posture; it detects any kind of attack or abnormal behavior in accessing the system and sends an alert to the administrator who can check, understand, and review on time to ensure that all activities are legit."
 

Cons

"The initial onboarding was causing us some confusion."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"Our customers no longer use Cloudflare because its service is subpar."
"The onboarding process can be improved a little bit."
"For the topic of improvement, providing some training material is one of my suggestions."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"In future releases, I would like to see two main improvements come to mind. First, the current solution requires maintaining two separate operating systems for FTD, which can be cumbersome. I'd love to see a single operating system for the FTD box."
"I would rate the stability a six out of ten. We had multiple issues with the stability."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"The area of license renewal should be improved. We normally renew our license every year."
"We have Microsoft and we have the E5 licenses, they have more EDR responses on certain emails. That's something that Cisco ESA on the cloud doesn't have. They don't do anything about MITRE attacks. They only detect if there is a malicious email or a threat and they remove it."
"We didn't get any malware, but a few phishing emails, maybe one or two, slipped in."
"The interface is dated. It has looked pretty much the same for 15 years or so. It would be helpful to be able to do everything from one spot. The centralized quarantine and reporting are completely separate from policy administration."
"In some cases, detection is missed, leading to false positives where genuine emails are flagged as spam."
"I assess the stability and reliability of the solution as seven out of ten."
"In the areas of improvement for Microsoft Defender for Office 365, the console is the biggest challenge for me."
"I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download."
"The custom alerts have to improve a lot."
"Microsoft Defender for Office 365 should be more proactive."
"This is quite an expensive solution and understanding the pricing model and features is quite complicated and it can, in fact, be a nightmare when dealing with Microsoft."
"I was looking for some advanced features, like if I would receive an email that contains a legitimate file type, but the content is malicious, how I can protect against that?"
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The solution is not that expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The prices are slightly expensive."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"It is a reasonably priced solution."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"It is not that costly. We pay for the solution through a contractor and pay an annual fee."
"The product's price falls on the higher side when compared to the other products on the market."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"The product is expensive."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"I know that the product is incredibly expensive."
"The product is very expensive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
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899,258 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
899,258 professionals have used our research since 2012.