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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (12th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (2nd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of August 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.4% compared to the previous year. The mindshare of Cisco Secure Email is 4.4%, down from 5.5% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 5.7%, down from 11.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3655.7%
Cisco Secure Email4.4%
Cloudflare One1.7%
Other88.2%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution has different options that can be used to differentiate DDoS attacks."
"Cloudflare, in my opinion, was easy to implement."
"Clover is the best product globally."
"Enables me to work from two locations."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."
"Cloudflare is simple to use."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"The return here is more security and fewer interruptions; it's more stability and productivity versus less productivity, and you could say that you're minimizing your costs by $65,000."
"Cisco's Secure Email integrates with Cisco Firewalls, utilizing the AMP as their anti-malware engine, which allows for information sharing between devices."
"Comparing Microsoft Defender and Cisco's Email Secure service, partners have noted that while Microsoft Defender offers email security, the tool's additional layer of protection provides further defense against threats like spam and phishing emails."
"Overall, it is a very good product, and I'm very happy with it."
"The system enables end users to manage their own whitelists/blacklists."
"It does a great job of preventing spam, malware, and ransomware."
"The reasons I chose Cisco Secure Email Gateway are the interface is - it's easy to use - and the support is great."
"Compared with other mail security things, Cisco Secure Email was much better and easy to deploy also."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."
"Does a thorough job of examining email and URLs for malicious content."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"Defender is a SaaS platform, so it offers more flexibility. Managing the permissions is easier. The solution's automated detection and response features are scalable."
"The insights provided with Microsoft Defender for Office 365 are helpful because it comes with the E5 license, and by default, we can use a lot of capabilities."
"The risk level notifications are most valuable. We get to know what kind of intrusion or attack is there, and we can fix a problem on time."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
 

Cons

"Operating and tuning the product is difficult."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"Feedback could be enhanced."
"Automation could be improved where you can easily add a TLS and SSL certificate to an application or web app if the developer did not include it."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"For the topic of improvement, providing some training material is one of my suggestions."
"Cloudflare DDoS has poor technical support."
"The graphical user interface is not user-friendly like other vendors. I find it very difficult at times to find some options on the UI."
"It would be nice to have an easier way to check on the health of the system, how stressed these appliances are. Sure, you can do it, but it would be helpful to have an easier way to do it, maybe even at a glance."
"One of the things that Cisco could improve on with IronPort is the support."
"We cannot manage multiple devices from a single UI."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"The primary areas for improvement are the pricing and the complexity of deployment."
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"There could be additional DLP functionality for it."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download."
"There is a different console for different things; I just want one consolidated console."
"I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware."
"The product must provide better malware detection."
"The pre-sales cost calculations could be more transparent."
"The changes to customer service, specifically the new model for support agreements, are not favorable."
"To improve Microsoft Defender for Office 365, it would be nice to have more accessibility for users to see on their end what they are doing that could cause a threat."
 

Pricing and Cost Advice

"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"Cloudflare Zero Trust Platform's pricing is good."
"The solution's pricing lacks transparency."
"The solution is not that expensive."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The prices are slightly expensive."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price is significantly high."
"Cisco Secure Email is not expensive, and licensing costs are yearly."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"At times, we feel the pricing is a bit too high, but then, there is also room for discounts. We enjoy a lot of discounts, and that is why we are still with them. There are no costs in addition to the standard licensing fees."
"There were no other costs in addition to the standard licensing fees."
"It's adapted to the market. It's similar to other vendors. We at least don't have many problems regarding that because Cisco is adaptable on that side. When we present the solutions to the customers, we tend to achieve the goals that the customer has in terms of the budget for such implementations."
"It is a reasonably priced solution."
"There are additional fees for adding features."
"The pricing has become expensive."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"It's a user-base subscription."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
11%
Outsourcing Company
9%
Financial Services Firm
8%
Financial Services Firm
11%
Manufacturing Company
9%
Outsourcing Company
7%
Computer Software Company
7%
Computer Software Company
11%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: August 2026.
909,099 professionals have used our research since 2012.