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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
4th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.5%, down from 6.4% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.3%
Cisco Secure Email4.5%
Cloudflare One1.6%
Other87.6%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The blocking feature is very good."
"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"Enables me to work from two locations."
"I'm very satisfied with the environment and the dashboard."
"Cloudflare Access is a stable solution."
"The most valuable features are protection against ransomware and spam."
"Overall, the ease of migration to Cisco's cloud email security from the on-prem solution was a positive experience."
"The product's initial setup phase was easy."
"The tool has a DLP solution which we can implement. Its database is updated regularly."
"The security features are valuable."
"The most significant enhancement we've gained is in terms of security through the upgrade we received."
"Users were able to do a check by themselves on quarantined emails. They could check if a valid email had been stopped, if it matched up with the SPF certification."
"We rely heavily on antivirus protection, email content filtering, and authentication mechanisms to ensure compliance with email security. Regarding phishing attempts, while phishing protection features are crucial, we also emphasize user education as a critical defence. The intelligence services Cisco provides, such as the Cisco Intelligence Center, play a significant role in analyzing and validating threats, including phishing attempts, in our email security practices."
"The features I appreciate most about Microsoft Defender for Office 365 are admin notifications for potential threats along with protecting our Microsoft apps such as Outlook from potential phishing attacks."
"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."
"It has significantly decreased my time to detection and response."
"The feature I like the most about Microsoft Defender for Office 365 is that it typically runs in the background—you do not know it is there until you need to access it."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"Microsoft Defender for Office 365 saves me time; it does save a lot of time, especially with the automation."
"The deployment capability is a great feature, and we're able to activate this feature throughout France with a click."
"The most valuable feature is the integration; it's a single console, so we don't have to switch around between multiple products, and another valuable feature is the ease of operations and maintenance."
 

Cons

"I would like them to include a VPN feature to provide a secure connection to the data center."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"For the topic of improvement, providing some training material is one of my suggestions."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"They don't have a person to provide support for customers using the solution under their free plan."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"Our customers no longer use Cloudflare because its service is subpar."
"The solution does not have a strong outbound service. It should also integrate DLP."
"My opinion on the licensing of this solution is that it is a mess that needs sorting out. I am not particularly bothered by pricing as I administer it and make recommendations for people to buy or not to buy."
"We use the CLI for management, but it's not very good. It's based on Java and it's very difficult to use."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"The interface is dated. It has looked pretty much the same for 15 years or so. It would be helpful to be able to do everything from one spot. The centralized quarantine and reporting are completely separate from policy administration."
"The UI is definitely one area of improvement because it doesn't match other interfaces and the navigation can be a little clunky."
"I have some frustrations with the user experience in the interface, specifically with regard to making a list of people for whom I want to allow email access."
"Better dashboards and more interactive overviews would be nice, but the current functionality is sufficient."
"Configuration requires going to a lot of places rather than just accessing one tab."
"The UI needs to be more user-friendly."
"Several simulation options are available within 365, and the phishing simulation could be better."
"Microsoft Defender for Office 365 should improve the troubleshooting tools. It's unclear whether the device is blocked at the firewall level or at the device itself. The granularity needed for troubleshooting is currently lacking. From my perspective, Microsoft should address this issue to benefit many users who likely share the same sentiment."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"I'd like some additional features any product can give me to protect our environment in a better way."
"We need to be able to whitelist data at the backend."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
 

Pricing and Cost Advice

"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"Cloudflare Zero Trust Platform's pricing is good."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The prices are slightly expensive."
"The solution's pricing lacks transparency."
"The solution is not that expensive."
"I rate the pricing a ten out of ten on a scale where one means it is less cost-effective, and ten means it is the most cost-effective solution."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"The licensing was all transferred."
"The pricing for the Cisco Email Security Appliance involves recurring costs for licenses based on the contracted time frame, such as one year, three years, or five years. Renewals are required after the license expires."
"The license was not per user, the license model was per feature. You could choose anti-virus, anti-spam, etc. It was feature-based and charged yearly."
"Cisco Secure Email is expensive, but we get what we pay for."
"The pricing is good."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"It's a user-base subscription."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The product is very expensive."
"The pricing has become expensive."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The license is expensive because the cost is based on the number of users."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
902,495 professionals have used our research since 2012.