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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (9th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of July 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.5% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.2% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.1%, down from 12.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.1%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other87.5%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"Enables me to work from two locations."
"It is a stable solution."
"Cloudflare DDoS mitigates DDoS attacks."
"Clover is the best product globally."
"We mostly use Cloudflare WAF, and gets basic Cloudflaire DDoS, caching as extra bonus . We like the factor these features are all integrated into 1 console, simple to manage."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"What I find the most valuable about Cisco Secure Email is that the logs are not that difficult to see even if you're not used to them. The logs are reasonably readable and diagnosing the problem is not too hard with them."
"It is a user-friendly product."
"The most valuable features are protection against ransomware and spam."
"Cisco Secure Email is a budget-friendly solution."
"The Cisco Email Security Appliance has enabled us to reduce spam by at least 30% compared to our previous solution."
"For what you get for the product, the support, and the overall stability, it is definitely a good return on investment."
"The product blocks spam emails."
"The return here is more security and fewer interruptions; it's more stability and productivity versus less productivity, and you could say that you're minimizing your costs by $65,000."
"Technical support is very good. They are knowledgeable and respond quickly."
"Does a thorough job of examining email and URLs for malicious content."
"Defender helps us prioritize threats across our organization."
"It’s easy to handle integrations, and we don't need a lot of people in our IT team."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"The basic features are okay and I'm satisfied with the Defender."
 

Cons

"The onboarding process can be improved a little bit."
"Our subscription plan for the solution has a limitation of bot signatures."
"For the topic of improvement, providing some training material is one of my suggestions."
"Feedback could be enhanced."
"Automation could be improved where you can easily add a TLS and SSL certificate to an application or web app if the developer did not include it."
"The initial onboarding was causing us some confusion."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"They don't have a person to provide support for customers using the solution under their free plan."
"Cisco is already providing a very good environment with the IronPort solution, but there could be some more integration with other products. For instance, an integration with the EDR solution could be there to raise an alert."
"We didn't get any malware, but a few phishing emails, maybe one or two, slipped in."
"My opinion on the licensing of this solution is that it is a mess that needs sorting out. I am not particularly bothered by pricing as I administer it and make recommendations for people to buy or not to buy."
"The solution does not have a strong outbound service. It should also integrate DLP."
"If you are not a technical guy, it is hard to maneuver, but as soon as you work on it, it gets better and better. If there was a better way to know how to do things or how to find things, it would be good."
"We would like to see more options for the customization of content filters."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"The interface is dated. It has looked pretty much the same for 15 years or so."
"The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"I was looking for some advanced features, like if I would receive an email that contains a legitimate file type, but the content is malicious, how I can protect against that?"
"There is a different console for different things; I just want one consolidated console."
"This product's effectiveness could be improved, in terms of detecting unwanted spam or even malware between the emails, compared to other products."
"I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware."
"There needs to be an improvement in integrating the product to work across multiple operating systems, and to have better support for non-Microsoft file types."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
 

Pricing and Cost Advice

"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The prices are slightly expensive."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"The solution is not that expensive."
"The solution's pricing lacks transparency."
"The licensing was all transferred."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"You're going to get what you pay for. If you're not willing to pay the price of Cisco, you're not going to get a product that's as good as Cisco. I don't think Cisco is overpriced, because for the last two years I've been comparing it to Microsoft and Cisco has been cheaper and given us more features."
"It is a reasonably priced solution."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"It's adapted to the market. It's similar to other vendors. We at least don't have many problems regarding that because Cisco is adaptable on that side. When we present the solutions to the customers, we tend to achieve the goals that the customer has in terms of the budget for such implementations."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is very expensive."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"The pricing has become expensive."
"The license is expensive because the cost is based on the number of users."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"I know that the product is incredibly expensive."
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Top Industries

By visitors reading reviews
Construction Company
18%
Comms Service Provider
10%
Financial Services Firm
9%
Outsourcing Company
8%
Financial Services Firm
12%
Manufacturing Company
9%
Outsourcing Company
7%
Computer Software Company
7%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
907,664 professionals have used our research since 2012.