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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
4th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.5%, down from 6.4% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.3%
Cisco Secure Email4.5%
Cloudflare One1.6%
Other87.6%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"Cloudflare Access is a stable solution."
"Cloudflare DDoS mitigates DDoS attacks."
"It is a stable solution."
"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"I'm very satisfied with the environment and the dashboard."
"The solution is very configurable. It has enabled us to configure some specific filters to stop emails that general configurations didn't stop. It's a powerful solution. It can analyze a lot of emails simultaneously, with no problems of capacity or system load."
"Anti-Spam and Advanced Malware Protection are the most valuable features; they provide protection from most email threats and we also have the option to block Zero-day attacks."
"It is doing its work. It is doing what it was actually designed to do. It has ensured we don't have business email compromises, and it has also ensured that our brand Galaxy is unique all year round."
"This is a great product with wonderful support."
"It blocks bulk marketing messages, graymail, spam, and provides advanced malware protection."
"The tech engineers are very knowledgeable."
"We chose Cisco Iron Port as it delivers strong email security protection and our company needed it to protect the company's email systems from spam, email viruses, .exe files, unwanted email from unwanted sender etc."
"We rely heavily on antivirus protection, email content filtering, and authentication mechanisms to ensure compliance with email security. Regarding phishing attempts, while phishing protection features are crucial, we also emphasize user education as a critical defence. The intelligence services Cisco provides, such as the Cisco Intelligence Center, play a significant role in analyzing and validating threats, including phishing attempts, in our email security practices."
"The technical support is good and quick to resolve issues."
"Microsoft Defender for Office 365 helps people to work remotely. It is a secure solution. We don't need to use our company's computers or get VPN connections to the networks. I can control how they share screens and what they send to the devices. It keeps our organizations confidential and sensitive information safe."
"We have seen a return on investment because if we would have received a phishing email, Microsoft Defender for Office 365 would help out to detect the threat instead of crashing down the whole company."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"Defender helps us prioritize threats across our organization."
"The good part is that you don't have to configure it, which is very convenient."
"It definitely is a must for email protection and O365 app DLP, and combined with Microsoft Defender for Endpoint, Microsoft Defender for Identity, and MCAS, it provides a holistic solution for threat protection, email protection, O365 apps protection, and DLP for both internal and external risks."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
 

Cons

"Our subscription plan for the solution has a limitation of bot signatures."
"Cloudflare DDoS has poor technical support."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"They don't have a person to provide support for customers using the solution under their free plan."
"The response time for support must be reduced."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"For the topic of improvement, providing some training material is one of my suggestions."
"We have Microsoft and we have the E5 licenses, they have more EDR responses on certain emails. That's something that Cisco ESA on the cloud doesn't have. They don't do anything about MITRE attacks. They only detect if there is a malicious email or a threat and they remove it."
"The UI is definitely one area of improvement because it doesn't match other interfaces and the navigation can be a little clunky."
"One of the things that Cisco could improve on with IronPort is the support."
"The tool's pricing can be improved."
"The product's GUI for the dashboard needs improvement."
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"We have been struggling in the last month with Cisco encryption and with the S/MIME encryption. I don't know if it is an issue on our side or if these features of the solution are not working very well."
"The Forged Email Detection feature needs improvement, particularly with domain. The sensors are not that good and the rules sets are unclear."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"The XDR dashboard has room for improvement."
"The cost of Security Copilot is up there right now, and I think it needs to come down for more people to adopt."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"There is a different console for different things; I just want one consolidated console."
"The product must provide better malware detection."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Too many false positives and lacks an accurate capability to detect malicious SharePoint sites."
 

Pricing and Cost Advice

"The solution is not that expensive."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"Cloudflare Zero Trust Platform's pricing is good."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"We do annual licensing for Cisco Secure Email Gatewayand SMA together, and possibly SmartNet support. Packaged together, the cost is just under $38,000."
"The pricing for the Cisco Email Security Appliance involves recurring costs for licenses based on the contracted time frame, such as one year, three years, or five years. Renewals are required after the license expires."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"It is a reasonably priced solution."
"It is not that costly. We pay for the solution through a contractor and pay an annual fee."
"Cisco Secure Email is not expensive, and licensing costs are yearly."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"I know that the product is incredibly expensive."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is expensive."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
11%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
900,196 professionals have used our research since 2012.