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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.8
Reviews Sentiment
6.7
Number of Reviews
22
Ranking in other categories
Secure Web Gateways (SWG) (15th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (11th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (12th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (3rd), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of March 2026, in the Email Security category, the mindshare of Cloudflare One is 1.5%, down from 1.8% compared to the previous year. The mindshare of Cisco Secure Email is 5.2%, down from 6.9% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 8.8%, down from 13.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3658.8%
Cisco Secure Email5.2%
Cloudflare One1.5%
Other84.5%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It will take the blow rather than our applications should an attack occur."
"This solution is easy to understand and easy to configure."
"It's the endpoint exposition. We don't need to expose our VPN server to the internet and need a zero-test solution. I can apply some conditional access to the endpoint that's connecting to our network to check their security policies or the security condition of their workstation. Once the workstation is trying to connect to my internal network, then I would like to check the discrete condition of these endpoints that are trying to access my internal network. We created some conditional access. We have CrowdStrike, to check if the CrowdStrike is installed, to check if it's updated, and to check for Windows updates. We created some conditional policies to check it."
"The blocking feature is very good."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"Cloudflare is by far the most effective solution that I have come across."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"Cloudflare, in my opinion, was easy to implement."
"The technical support from Cisco is perfect."
"It does a great job of preventing spam, malware, and ransomware. I can only go by what people have told me and what I've seen, but I have not seen spam in a year and a half to two years in my own company mailbox. And there are not a lot of catches where it's catching something that should have gotten through, either."
"The most significant enhancement we've gained is in terms of security through the upgrade we received."
"The strong point of the solution is that we hardly get any spam emails because of Cisco Secure Email."
"The most valuable features are protection against ransomware and spam."
"Cisco's Secure Email integrates with Cisco Firewalls, utilizing the AMP as their anti-malware engine, which allows for information sharing between devices."
"It provides good IT assistance."
"The advanced phishing protection and the integration with the awareness tool that Cisco has embedded into the solution to bring awareness to the customers about the dangers of phishing attacks and other things that come from email are the most valuable features."
"Microsoft Defender for Office 365 is a stable solution."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"Microsoft Defender for Office 365 helps people to work remotely. It is a secure solution. We don't need to use our company's computers or get VPN connections to the networks. I can control how they share screens and what they send to the devices. It keeps our organizations confidential and sensitive information safe."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"The ability to respond to threats if very important."
"The good part is that you don't have to configure it, which is very convenient."
 

Cons

"Our customers no longer use Cloudflare because its service is subpar."
"Lacks a VPN feature to provide a secure connection to the data center."
"Operating and tuning the product is difficult."
"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"They don't have a person to provide support for customers using the solution under their free plan."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"The reporting functionality needs to be improved."
"The solution does not have a strong outbound service. It should also integrate DLP."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"We have occasionally had hardware problems because we are using an appliance-based solution, but that might change. We may consider going to virtual systems."
"The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console."
"The user interface is a bit complex."
"I would rate the stability a six out of ten. We had multiple issues with the stability."
"They can do it better with web links, with the URLs. They have a technology called Outbreak but it doesn't work as well as we would like."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"The custom alerts have to improve a lot."
"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"The phishing and spam filters could use some improvement."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"Configuration requires going to a lot of places rather than just accessing one tab."
"The GUI is sometimes slow to fetch the device report and could be improved."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The solution is not that expensive."
"The prices are slightly expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"Cisco Secure Email is more expensive than other products. I rate it a five out of ten. There are no additional costs. You only need to pay the subscription amounts."
"The price is significantly high."
"There are additional fees for adding features."
"You're going to get what you pay for. If you're not willing to pay the price of Cisco, you're not going to get a product that's as good as Cisco. I don't think Cisco is overpriced, because for the last two years I've been comparing it to Microsoft and Cisco has been cheaper and given us more features."
"As per market availability, this solution is more expensive than other vendors."
"Licensing costs depend on how many users there are. It could range between $5 and $7 per month, per user."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"It is an expensive product. I rate its pricing an eight or nine."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"The product is expensive."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The license is expensive because the cost is based on the number of users."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
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Top Industries

By visitors reading reviews
Comms Service Provider
10%
Computer Software Company
10%
Financial Services Firm
8%
Manufacturing Company
8%
Computer Software Company
10%
Manufacturing Company
10%
Financial Services Firm
8%
Comms Service Provider
6%
Computer Software Company
13%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise2
Large Enterprise10
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents...
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: March 2026.
884,706 professionals have used our research since 2012.