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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (9th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of July 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.5% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.2% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.1%, down from 12.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.1%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other87.5%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare is by far the most effective solution that I have come across."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"Clover is the best product globally."
"The solution has different options that can be used to differentiate DDoS attacks."
"Cloudflare DDoS mitigates DDoS attacks."
"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"The most valuable features are protection against ransomware and spam."
"The Cisco Email Security Appliance has enabled us to reduce spam by at least 30% compared to our previous solution."
"At one point, there was a zero-day attack. The Cisco appliance detected it and stopped it, helping us out. We avoided the attack and potential damage."
"Introducing Cisco Secure Email Gateway systems was a set change for us and reduced the number of unwanted emails by a huge factor, a benefit that has continued from when we first got the devices until today."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive. Previously, our users had to deal with nine million additional emails across the organization, which is nearly 1,000 emails per user to have to deal with a month. That's a massive amount for our staff to deal with and probably several hours of their time. We have a lot of clinical staff, being a hospital. We want to make our staff as productive as possible. By removing a lot of that spam and phishing type emails, this allows them to do their job."
"Comparing Microsoft Defender and Cisco's Email Secure service, partners have noted that while Microsoft Defender offers email security, the tool's additional layer of protection provides further defense against threats like spam and phishing emails."
"We like the in-built features, like the email filtering based on the IP and domain, and Cisco has its own blacklisted domains and IPs, which is very good because this filters around 70 percent of emails from spam and we are seeing fewer false positives with this."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive."
"The technical support is good and quick to resolve issues."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"Microsoft Defender for Office 365's most valuable feature is its performance."
"The stability of Microsoft Defender for Office 365 is fantastic."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"It has helped us in improving our security posture; it detects any kind of attack or abnormal behavior in accessing the system and sends an alert to the administrator who can check, understand, and review on time to ensure that all activities are legit."
"My experience deploying Microsoft Defender for Office 365 was seamless."
"We have seen a return on investment because if we would have received a phishing email, Microsoft Defender for Office 365 would help out to detect the threat instead of crashing down the whole company."
 

Cons

"Feedback could be enhanced."
"Our subscription plan for the solution has a limitation of bot signatures."
"They don't have a person to provide support for customers using the solution under their free plan."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"The response time for support must be reduced."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"The tool's pricing can be improved."
"I would like to see features like AI since it is currently an area that the product lacks."
"Don't neglect that because if you just try to rely on Cisco support you're going to notice pretty consistent slowdowns."
"The Forged Email Detection feature needs improvement, particularly with domain. The sensors are not that good and the rules sets are unclear."
"The configuration UI should be made more intuitive. Currently, it takes a while to understand how to do the basic configurations."
"Better dashboards and more interactive overviews would be nice, but the current functionality is sufficient."
"The graphical user interface is not user-friendly like other vendors. I find it very difficult at times to find some options on the UI."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"Microsoft wants its well-paying customers to finish testing some of its half-baked products, find bugs, and report bugs back to Microsoft's team, which is a little frustrating for those who have to manage it and roll it up to thousands of people across the organization."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"I'd like some additional features any product can give me to protect our environment in a better way."
"The cost of Security Copilot is up there right now, and I think it needs to come down for more people to adopt."
 

Pricing and Cost Advice

"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution is not that expensive."
"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"Cisco Secure Email is not expensive, and licensing costs are yearly."
"The license was not per user, the license model was per feature. You could choose anti-virus, anti-spam, etc. It was feature-based and charged yearly."
"The product's price falls on the higher side when compared to the other products on the market."
"There were no other costs in addition to the standard licensing fees."
"Cisco Secure Email is expensive, but we get what we pay for."
"It is an expensive product. I rate its pricing an eight or nine."
"The pricing is good."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is expensive."
"The pricing is normal. Considering its popularity, it's not overpriced."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"I know that the product is incredibly expensive."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
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902,988 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
11%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
902,988 professionals have used our research since 2012.