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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
4th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.5%, down from 6.4% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.3%
Cisco Secure Email4.5%
Cloudflare One1.6%
Other87.6%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It is a stable solution."
"Clover is the best product globally."
"We mostly use Cloudflare WAF, and gets basic Cloudflaire DDoS, caching as extra bonus . We like the factor these features are all integrated into 1 console, simple to manage."
"Cloudflare, in my opinion, was easy to implement."
"It's the endpoint exposition. We don't need to expose our VPN server to the internet and need a zero-test solution. I can apply some conditional access to the endpoint that's connecting to our network to check their security policies or the security condition of their workstation. Once the workstation is trying to connect to my internal network, then I would like to check the discrete condition of these endpoints that are trying to access my internal network. We created some conditional access. We have CrowdStrike, to check if the CrowdStrike is installed, to check if it's updated, and to check for Windows updates. We created some conditional policies to check it."
"Cloudflare is by far the most effective solution that I have come across."
"Cloudflare is simple to use."
"I'm very satisfied with the environment and the dashboard."
"Cisco's Secure Email integrates with Cisco Firewalls, utilizing the AMP as their anti-malware engine, which allows for information sharing between devices."
"Anti-Spam and Advanced Malware Protection are the most valuable features; they provide protection from most email threats and we also have the option to block Zero-day attacks."
"Spam controls are excellent because they are a powerful feature that operates almost effortlessly."
"The filtering is definitely better at catching both spam and malicious messages, and there's a lot of extremely granular ability for setting up rules. You can do it the way you want to. The Microsoft solution tends to be pretty limited in how it allows some of that to be done."
"The solution is valuable if you are looking for a security email gateway that provides you with the most services possible."
"There are a lot of filters for scam emails and things like that work out of the box. You can also use the antivirus features. I like its features."
"Compared with other mail security things, Cisco Secure Email was much better and easy to deploy also."
"It has the ability to tell us, after an email has been delivered, where else it went, once it got inside. Maybe it's something we wanted it to stop and it didn't stop it, but it notified us later that it was something that it should have stopped. It can give us a trajectory of all the other places that it went internally and it can tell us what files were transferred as well."
"It definitely is a must for email protection and O365 app DLP, and combined with Microsoft Defender for Endpoint, Microsoft Defender for Identity, and MCAS, it provides a holistic solution for threat protection, email protection, O365 apps protection, and DLP for both internal and external risks."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"Scalability-wise, I do not think there are any issues so far."
"The risk level notifications are most valuable. We get to know what kind of intrusion or attack is there, and we can fix a problem on time."
"Does a thorough job of examining email and URLs for malicious content."
"One of our clients didn't have the budget to invest in a SOC team, but we deployed the solution for them, and they now run a SOC with only one analyst."
"Overall, I would rate Microsoft Defender for Office 365 at a ten."
"The ability to respond to threats if very important."
 

Cons

"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"I would like them to include a VPN feature to provide a secure connection to the data center."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"Operating and tuning the product is difficult."
"They don't have a person to provide support for customers using the solution under their free plan."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"Better dashboards and more interactive overviews would be nice, but the current functionality is sufficient."
"Cisco Secure Email can be improved from the administrator's point of view. Usually, you have to work with different areas, and they can try to make it easy for the administrator to use different functions."
"I would rate the stability a six out of ten. We had multiple issues with the stability."
"Scalability has certain shortcomings and needs to be improved because there are service providers who provide better scalability.v"
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"The area of license renewal should be improved. We normally renew our license every year."
"The interface is dated. It has looked pretty much the same for 15 years or so."
"The user interface of the Email Security Gateway should be improved."
"You should be able to deploy Defender for every subscription without the need to add servers."
"The pre-sales cost calculations could be more transparent."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"The visibility for the weaknesses in the system and unauthorized access can be improved."
"We need to be able to whitelist data at the backend."
"In the areas of improvement for Microsoft Defender for Office 365, the console is the biggest challenge for me."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"There's room for improvement regarding the time frame for retrieving emails."
 

Pricing and Cost Advice

"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"The solution is not that expensive."
"The prices are slightly expensive."
"The solution's pricing lacks transparency."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"The licensing was all transferred."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"There were no other costs in addition to the standard licensing fees."
"At times, we feel the pricing is a bit too high, but then, there is also room for discounts. We enjoy a lot of discounts, and that is why we are still with them. There are no costs in addition to the standard licensing fees."
"The pricing for the Cisco Email Security Appliance involves recurring costs for licenses based on the contracted time frame, such as one year, three years, or five years. Renewals are required after the license expires."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"It's a user-base subscription."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The product is very expensive."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The pricing has become expensive."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is expensive."
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Top Industries

By visitors reading reviews
Construction Company
20%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
11%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
899,917 professionals have used our research since 2012.