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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
4th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.5%, down from 6.4% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.3%
Cisco Secure Email4.5%
Cloudflare One1.6%
Other87.6%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"Cloudflare Access is a stable solution."
"Cloudflare Access is part of the Zero Trust philosophy."
"I'm very satisfied with the environment and the dashboard."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"The best feature is rate limiting. If I'm expecting 500 visits per hour, Cloudflare will limit the requests if I suddenly get 50,000."
"The solution has different options that can be used to differentiate DDoS attacks."
"The logs are easily readable and help diagnose problems, although they can be difficult to find initially. The solution addresses our email security, but for the rest of our security, we would use multiple vendors. It covers everything through email, like antivirus, IDS, and IPS."
"I can customize the configuration and policies."
"Cisco Secure Email has strong inbound services."
"It provided a platform to sell a service to customers."
"The malicious URL scanning, as well as the anti-malware features, have been really useful for us in our environment."
"We like the in-built features, like the email filtering based on the IP and domain, and Cisco has its own blacklisted domains and IPs, which is very good because this filters around 70 percent of emails from spam and we are seeing fewer false positives with this."
"Cisco Secure Email's most valuable is email certification."
"The tool has a DLP solution which we can implement. Its database is updated regularly."
"Microsoft so far has been good; we haven't faced any kind of disruption or anything else, it's a good product and good platform, I must say, and overall it's a good product and good service and we haven't dealt with bugs or glitches."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"Microsoft Defender for Office 365 is a cloud-based email filtering service that helps protect our organization against unknown malware and viruses by providing robust zero-day protection and includes features to safeguard our organization from harmful links in real-time."
"The risk level notifications are most valuable. We get to know what kind of intrusion or attack is there, and we can fix a problem on time."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"I would say that 90% of the spam and phishing attack emails get blocked right off the bat."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
 

Cons

"The onboarding process can be improved a little bit."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"Cloudflare Zero Trust Platform needs to improve its documentation. It took time to do the implementation."
"For the topic of improvement, providing some training material is one of my suggestions."
"Our customers no longer use Cloudflare because its service is subpar."
"Cisco is not good in dealing proactively or even reactively, so we end up relying on partners."
"The scalability must be improved."
"Many smaller businesses opt for more cost-effective solutions, such as Gmail or Hotmail accounts, instead of investing in Cisco Secure Email, given its higher cost."
"We have been struggling in the last month with Cisco encryption and with the S/MIME encryption. I don't know if it is an issue on our side or if these features of the solution are not working very well."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"In some cases, detection is missed, leading to false positives where genuine emails are flagged as spam."
"I would like them to add some clustering or high availability features."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"Microsoft wants its well-paying customers to finish testing some of its half-baked products, find bugs, and report bugs back to Microsoft's team, which is a little frustrating for those who have to manage it and roll it up to thousands of people across the organization."
"This product's effectiveness could be improved, in terms of detecting unwanted spam or even malware between the emails, compared to other products."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats."
"The product must provide better malware detection."
"I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"The solution is not that expensive."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"Cloudflare Zero Trust Platform's pricing is good."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"You're going to get what you pay for. If you're not willing to pay the price of Cisco, you're not going to get a product that's as good as Cisco. I don't think Cisco is overpriced, because for the last two years I've been comparing it to Microsoft and Cisco has been cheaper and given us more features."
"Cisco Secure Email is not expensive, and licensing costs are yearly."
"We were using Proofpoint and then we switched to Cisco... reportability was one of the main reasons we switched, but the biggest one was cost. If you can get an equivalent functionality for a better price it's wise to do so. That's what our primary decision came down to: We could get equivalent functionality at a lower price point."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"There are additional fees for adding features."
"As per market availability, this solution is more expensive than other vendors."
"There were no other costs in addition to the standard licensing fees."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"I know that the product is incredibly expensive."
"The pricing has become expensive."
"The product is very expensive."
"The license is expensive because the cost is based on the number of users."
"It's a user-base subscription."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
899,283 professionals have used our research since 2012.