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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.8
Reviews Sentiment
6.7
Number of Reviews
22
Ranking in other categories
Secure Web Gateways (SWG) (16th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (11th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (2nd), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
62
Ranking in other categories
Cisco Security Portfolio (7th)
Microsoft Defender for Offi...
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of February 2026, in the Email Security category, the mindshare of Cloudflare One is 1.4%, down from 1.7% compared to the previous year. The mindshare of Cisco Secure Email is 5.1%, down from 7.1% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 9.1%, down from 13.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3659.1%
Cisco Secure Email5.1%
Cloudflare One1.4%
Other84.4%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
BD
Chief Information Security Officer at Abcl
Threat intelligence with fast attack detection enables comprehensive email protection
In some cases, detection is missed, leading to false positives where genuine emails are flagged as spam. This could result in users not opening genuine emails. We have highlighted this to Cisco because sometimes phishing or marketing campaigns, which are genuine, are incorrectly flagged as spam. The solution should better analyze the actual content rather than only focusing on the email header or origin.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"Cloudflare DDoS mitigates DDoS attacks."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"Cloudflare Access is part of the Zero Trust philosophy."
"Clover is the best product globally."
"It will take the blow rather than our applications should an attack occur."
"Cloudflare, in my opinion, was easy to implement."
"I'm very satisfied with the environment and the dashboard."
"Spam controls are excellent because they are a powerful feature that operates almost effortlessly."
"We like the in-built features, like the email filtering based on the IP and domain. Cisco has its own blacklisted domains and IPs, which is very good. This filters around 70 percent of emails from spam, and we are seeing fewer false positives with this."
"There were detailed logs available. That was a seriously good feature... It turns out these were actually spoof emails that came into our environment. I got to know about them from the log system."
"Cisco Secure Email is a budget-friendly solution."
"Cisco's Secure Email integrates with Cisco Firewalls, utilizing the AMP as their anti-malware engine, which allows for information sharing between devices."
"The most significant enhancement we've gained is in terms of security through the upgrade we received."
"It does a great job of preventing spam, malware, and ransomware. I can only go by what people have told me and what I've seen, but I have not seen spam in a year and a half to two years in my own company mailbox. And there are not a lot of catches where it's catching something that should have gotten through, either."
"It integrates with Active Directory and we can limit specific users to using specific applications."
"Does a thorough job of examining email and URLs for malicious content."
"Scalability-wise, I do not think there are any issues so far."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"The ability to respond to threats if very important."
"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"The two main features that prove most beneficial for us are URL scanning and attachment scanning."
 

Cons

"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"They don't have a person to provide support for customers using the solution under their free plan."
"Lacks a VPN feature to provide a secure connection to the data center."
"The onboarding process can be improved a little bit."
"Operating and tuning the product is difficult."
"For the topic of improvement, providing some training material is one of my suggestions."
"The response time for support must be reduced."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"The discontinuation of physical hardware solutions is a significant area for improvement in Cisco Email Security Appliance. This decision has posed challenges as virtual appliances are now the only option, which may not be suitable for all industries. The uncertainty regarding the future of the hardware aspect of the solution is a notable concern."
"The solution needs to improve its advanced phishing filters. It is very good at filtering things which have bad reputations. However, when phishing or malicious emails are new or coming from a legitimate source, we don't feel that the solution is working."
"The user interface of the Email Security Gateway should be improved."
"In future releases, I would like to see two main improvements come to mind. First, the current solution requires maintaining two separate operating systems for FTD, which can be cumbersome. I'd love to see a single operating system for the FTD box."
"I would like them to add some clustering or high availability features."
"The management features of the product are not up to date."
"The area of license renewal should be improved. We normally renew our license every year. There is a feature called smart licensing, and I switched from the legacy mode to the smart licensing mode because of what I thought smart licensing does. I thought it would make licensing renewal seamless and very swift, but ever since I've switched to smart licensing, each time I want to renew my license, it is a whole lot of headache. The process is not smooth, and I had to keep calling Cisco TAC to see how the issue can be resolved. At one point, I wanted to revert back to the legacy mode, but I can't revert. Once you switch from the legacy mode to the smart licensing mode, you can't revert. They should improve on the visibility of the smart licensing mode so that it can indeed be smart and easier to use for the license renewal every year. That is one challenge."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster."
"The UI needs to be more user-friendly."
"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"Configuration requires going to a lot of places rather than just accessing one tab."
"The XDR dashboard has room for improvement."
"The certification training for Defender for 365 needs to be deeper and incorporate Sentinel. I took all the security courses except one, and Sentinel isn't included."
 

Pricing and Cost Advice

"The solution is not that expensive."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The solution's pricing lacks transparency."
"Cloudflare Zero Trust Platform's pricing is good."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The prices are slightly expensive."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The price is significantly high."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"It is a relatively expensive option compared to other alternatives."
"It's adapted to the market. It's similar to other vendors. We at least don't have many problems regarding that because Cisco is adaptable on that side. When we present the solutions to the customers, we tend to achieve the goals that the customer has in terms of the budget for such implementations."
"The pricing for the Cisco Email Security Appliance involves recurring costs for licenses based on the contracted time frame, such as one year, three years, or five years. Renewals are required after the license expires."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"The licensing was all transferred."
"I know that the product is incredibly expensive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The pricing has become expensive."
"The product is very expensive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
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Top Industries

By visitors reading reviews
Computer Software Company
12%
Comms Service Provider
11%
Financial Services Firm
9%
Manufacturing Company
7%
Computer Software Company
16%
Manufacturing Company
9%
Financial Services Firm
8%
Comms Service Provider
6%
Computer Software Company
13%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise2
Large Enterprise10
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise25
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The user interface of the Email Security Gateway ( /products/security-gateway-reviews ) should be improved. It would ...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents...
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: February 2026.
882,207 professionals have used our research since 2012.