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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (20th), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of May 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.6% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.9%, down from 12.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.9%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other86.7%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"It is a stable solution."
"Cloudflare is by far the most effective solution that I have come across."
"Cloudflare is simple to use."
"Cloudflare Access is part of the Zero Trust philosophy."
"Cloudflare DDoS mitigates DDoS attacks."
"The best feature is rate limiting. If I'm expecting 500 visits per hour, Cloudflare will limit the requests if I suddenly get 50,000."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"The logs are easily readable and help diagnose problems, although they can be difficult to find initially. The solution addresses our email security, but for the rest of our security, we would use multiple vendors. It covers everything through email, like antivirus, IDS, and IPS."
"The tool comes with AI features. It is good for clients who already use Cisco products due to integration."
"Users were able to do a check by themselves on quarantined emails. They could check if a valid email had been stopped, if it matched up with the SPF certification."
"Comparing Microsoft Defender and Cisco's Email Secure service, partners have noted that while Microsoft Defender offers email security, the tool's additional layer of protection provides further defense against threats like spam and phishing emails."
"The user interface was quite friendly, it was quite easy to use, unlike some other Cisco products. Anybody could use it. You don't have to be familiar with IT to be able to handle navigating it."
"We like the in-built features, like the email filtering based on the IP and domain, and Cisco has its own blacklisted domains and IPs, which is very good because this filters around 70 percent of emails from spam and we are seeing fewer false positives with this."
"The strong point of the solution is that we hardly get any spam emails because of Cisco Secure Email."
"Cisco Secure Email is a budget-friendly solution."
"My experience with customer support and technical support for Microsoft Defender for Office 365 has been excellent."
"Defender has reduced the time our security team spends on tasks by 10 to 15 percent, allowing us to focus on other areas."
"The basic features are okay and I'm satisfied with the Defender."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"The email protection is excellent, especially in terms of anti-phishing policies."
"We use Microsoft Defender for its ability to integrate with existing business technologies, which is beneficial for protecting business areas."
"Defender helps us prioritize threats across our organization."
"Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the individuals within our organization who are affected."
 

Cons

"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"The onboarding process can be improved a little bit."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"There are some concerns in the way the architecture is set up, making it an area where improvements are required."
"Licensing is quite complicated for a number of customers, including ourselves."
"In some cases, detection is missed, leading to false positives where genuine emails are flagged as spam."
"The pricing needs to be reconsidered or enhanced."
"The user interface needs some improvement to become more user-friendly. The graphics could be better. It's designed more for a technical user rather than a business user."
"My opinion on the licensing of this solution is that it is a mess that needs sorting out. I am not particularly bothered by pricing as I administer it and make recommendations for people to buy or not to buy."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"We didn't get any malware, but a few phishing emails, maybe one or two, slipped in."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"The pre-sales cost calculations could be more transparent."
"The GUI is sometimes slow to fetch the device report and could be improved."
"You should be able to deploy Defender for every subscription without the need to add servers."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"The visibility for the weaknesses in the system and unauthorized access can be improved."
"Microsoft Defender for Office 365 should be more proactive."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution is not that expensive."
"As per market availability, this solution is more expensive than other vendors."
"The price is significantly high."
"Cisco Secure Email is not expensive, and licensing costs are yearly."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"The solution is expensive."
"It's adapted to the market. It's similar to other vendors. We at least don't have many problems regarding that because Cisco is adaptable on that side. When we present the solutions to the customers, we tend to achieve the goals that the customer has in terms of the budget for such implementations."
"It is a relatively expensive option compared to other alternatives."
"The pricing is good."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"The license is expensive because the cost is based on the number of users."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is expensive."
"The product is very expensive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
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Top Industries

By visitors reading reviews
Construction Company
20%
Comms Service Provider
11%
Financial Services Firm
9%
Manufacturing Company
6%
Financial Services Firm
11%
Computer Software Company
9%
Manufacturing Company
9%
Government
6%
Computer Software Company
12%
Financial Services Firm
9%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise12
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: April 2026.
894,830 professionals have used our research since 2012.