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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (20th), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of May 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.6% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.9%, down from 12.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.9%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other86.7%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"Cloudflare Access is a stable solution."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"The blocking feature is very good."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"Cloudflare is simple to use."
"Cloudflare Access is part of the Zero Trust philosophy."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"Apart from the improvement needed to the filters, it was all good."
"Overall, it is a very good product, and I'm very happy with it."
"Cisco Secure Email is a budget-friendly solution."
"Cisco Secure Email has strong inbound services."
"Compared with other mail security things, Cisco Secure Email was much better and easy to deploy also."
"It provided a platform to sell a service to customers."
"We are now protected against spam emails."
"For what you get for the product, the support, and the overall stability, it is definitely a good return on investment."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"The insights provided with Microsoft Defender for Office 365 are helpful because it comes with the E5 license, and by default, we can use a lot of capabilities."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"The most valuable feature of Microsoft Defender for Office 365 is data backups that we can provide through ticket requests."
"Defender helps us prioritize threats across our organization."
"Microsoft so far has been good; we haven't faced any kind of disruption or anything else, it's a good product and good platform, I must say, and overall it's a good product and good service and we haven't dealt with bugs or glitches."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"The deployment capability is a great feature."
 

Cons

"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"The initial onboarding was causing us some confusion."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"Our customers no longer use Cloudflare because its service is subpar."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"The initial onboarding was causing us some confusion."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"The Forged Email Detection feature needs improvement, particularly with domain. The sensors are not that good and the rules sets are unclear."
"The scalability must be improved."
"We didn't get any malware, but a few phishing emails, maybe one or two, slipped in."
"The graphical user interface is not user-friendly like other vendors. I find it very difficult at times to find some options on the UI."
"The initial setup was complex because I have two sites with physical clusters."
"The user interface is a bit complex."
"The graphical user interface is not user-friendly like other vendors. I find it very difficult at times to find some options on the UI."
"We have been struggling in the last month with Cisco encryption and with the S/MIME encryption."
"Microsoft Defender for Office 365 should be more proactive."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Several simulation options are available within 365, and the phishing simulation could be better."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats."
"There is room for improvement in terms of reporting."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats. For example, information about best practices on how to protect their own devices against hackers and scammers, such as educational information or training. This would help others have a better understanding of cyber security. Additionally, there can be more security features added."
 

Pricing and Cost Advice

"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The solution is not that expensive."
"The prices are slightly expensive."
"The solution's pricing lacks transparency."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"Licensing costs depend on how many users there are. It could range between $5 and $7 per month, per user."
"As per market availability, this solution is more expensive than other vendors."
"It is a relatively expensive option compared to other alternatives."
"There are additional fees for adding features."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"It is a super big router that costs a few hundred thousand dollars."
"In my previous organization, avoiding four instances of CryptoLocker within an estimated six month period is approximately $600,000 in lost time and effort. Our five year cost was about a million dollars, and the four outages that we had equated to 65 percent of that five year cost."
"It's a user-base subscription."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The product is very expensive."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The product is expensive."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
11%
Financial Services Firm
9%
Manufacturing Company
6%
Financial Services Firm
11%
Computer Software Company
9%
Manufacturing Company
9%
Government
5%
Computer Software Company
12%
Financial Services Firm
9%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise12
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: April 2026.
896,387 professionals have used our research since 2012.