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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (12th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (2nd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of August 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.4% compared to the previous year. The mindshare of Cisco Secure Email is 4.4%, down from 5.5% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 5.7%, down from 11.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3655.7%
Cisco Secure Email4.4%
Cloudflare One1.7%
Other88.2%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"It will take the blow rather than our applications should an attack occur."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"The best feature is rate limiting. If I'm expecting 500 visits per hour, Cloudflare will limit the requests if I suddenly get 50,000."
"The blocking feature is very good."
"Cloudflare DDoS mitigates DDoS attacks."
"The advanced phishing protection and the integration with the awareness tool that Cisco has embedded into the solution to bring awareness to the customers about the dangers of phishing attacks and other things that come from email are the most valuable features."
"The malicious URL scanning, as well as the anti-malware features, have been really useful for us in our environment."
"The most valuable features are Advanced Malware Protection, URL filtering, and of course Reputation Filtering."
"We are now protected against spam emails."
"Users were able to do a check by themselves on quarantined emails. They could check if a valid email had been stopped, if it matched up with the SPF certification."
"The return here is more security and fewer interruptions; it's more stability and productivity versus less productivity, and you could say that you're minimizing your costs by $65,000."
"This product is the complete solution and the real deal."
"It integrates with Active Directory and we can limit specific users to using specific applications."
"Microsoft Defender for Office 365 saves me time; it does save a lot of time, especially with the automation."
"The feature of Microsoft Defender for Office 365 that I like the most is probably the email features specifically, because those are the ones that a typical end user will accidentally click on a link not knowing what it is, and it'll catch it, and then it'll feed it over to Defender and stop the attack from happening before it actually can."
"The most valuable feature of Microsoft Defender for Office 365 is data backups that we can provide through ticket requests."
"I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection."
"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."
"The feature I like the most about Microsoft Defender for Office 365 is that it typically runs in the background—you do not know it is there until you need to access it."
"The ability to respond to threats if very important."
"The technical support is good and quick to resolve issues."
 

Cons

"Cloudflare Zero Trust Platform needs to improve its documentation. It took time to do the implementation."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"They don't have a person to provide support for customers using the solution under their free plan."
"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"I would like them to include a VPN feature to provide a secure connection to the data center."
"We use the CLI for management, but it's not very good. It's based on Java and it's very difficult to use."
"We would like to see more options for the customization of content filters."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"The hardware is not up to the mark. Two to three times a year we have complete downtime."
"The area of license renewal should be improved. We normally renew our license every year. There is a feature called smart licensing, and I switched from the legacy mode to the smart licensing mode because of what I thought smart licensing does. I thought it would make licensing renewal seamless and very swift, but ever since I've switched to smart licensing, each time I want to renew my license, it is a whole lot of headache. The process is not smooth, and I had to keep calling Cisco TAC to see how the issue can be resolved. At one point, I wanted to revert back to the legacy mode, but I can't revert. Once you switch from the legacy mode to the smart licensing mode, you can't revert. They should improve on the visibility of the smart licensing mode so that it can indeed be smart and easier to use for the license renewal every year. That is one challenge."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"Cisco is not good in dealing proactively or even reactively, so we end up relying on partners."
"The area of license renewal should be improved. We normally renew our license every year."
"The changes to customer service, specifically the new model for support agreements, are not favorable."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"This is quite an expensive solution and understanding the pricing model and features is quite complicated and it can, in fact, be a nightmare when dealing with Microsoft."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"We are waiting for better software to block viruses."
"They can improve their security in a way where a customer can know if all their attachments are safe or not to open through a report. The solution does its job perfectly, but it never reports to the customer whether those attachments have been stopped before or not."
 

Pricing and Cost Advice

"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The prices are slightly expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution's pricing lacks transparency."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The solution is not that expensive."
"Licensing costs depend on how many users there are. It could range between $5 and $7 per month, per user."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"We were using Proofpoint and then we switched to Cisco... reportability was one of the main reasons we switched, but the biggest one was cost. If you can get an equivalent functionality for a better price it's wise to do so. That's what our primary decision came down to: We could get equivalent functionality at a lower price point."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"I rate the pricing a ten out of ten on a scale where one means it is less cost-effective, and ten means it is the most cost-effective solution."
"We do annual licensing for Cisco Secure Email Gatewayand SMA together, and possibly SmartNet support. Packaged together, the cost is just under $38,000."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The pricing has become expensive."
"The product is very expensive."
"It's a user-base subscription."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"The pricing is normal. Considering its popularity, it's not overpriced."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
11%
Outsourcing Company
9%
Financial Services Firm
8%
Financial Services Firm
12%
Manufacturing Company
9%
Outsourcing Company
7%
Computer Software Company
7%
Computer Software Company
11%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: August 2026.
908,834 professionals have used our research since 2012.