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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (12th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (2nd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of August 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.4% compared to the previous year. The mindshare of Cisco Secure Email is 4.4%, down from 5.5% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 5.7%, down from 11.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3655.7%
Cisco Secure Email4.4%
Cloudflare One1.7%
Other88.2%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Clover is the best product globally."
"Cloudflare Access is part of the Zero Trust philosophy."
"The best feature is rate limiting. If I'm expecting 500 visits per hour, Cloudflare will limit the requests if I suddenly get 50,000."
"Cloudflare One has assisted in securing my remote workforce through a SASE solution with Cloudflare One and the Workers part, although I am not currently using the Workers component."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"It's a bit easy to handle Cisco Secure Email; it's not that difficult. For the logs, which are in PDF format, it's not hard to read them. We don't need Wireshark much to analyze the logs."
"It does a great job of preventing spam, malware, and ransomware. I can only go by what people have told me and what I've seen, but I have not seen spam in a year and a half to two years in my own company mailbox. And there are not a lot of catches where it's catching something that should have gotten through, either."
"From a functionality perspective, the platform is great."
"Spam controls are excellent because they are a powerful feature that operates almost effortlessly."
"We like the in-built features, like the email filtering based on the IP and domain, and Cisco has its own blacklisted domains and IPs, which is very good because this filters around 70 percent of emails from spam and we are seeing fewer false positives with this."
"This solution provides some benefits, like comfortable access to TAC support. You get prompt support when working directly with Cisco."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive. Previously, our users had to deal with nine million additional emails across the organization, which is nearly 1,000 emails per user to have to deal with a month. That's a massive amount for our staff to deal with and probably several hours of their time. We have a lot of clinical staff, being a hospital. We want to make our staff as productive as possible. By removing a lot of that spam and phishing type emails, this allows them to do their job."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive."
"Some of the valuable features on the email side are anti-phishing, anti-malware, and Safe Links."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
"Overall, I would rate Microsoft Defender for Office 365 at a ten."
"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
"Microsoft Defender for Office 365 has improved my organization's security. It makes it easier to manage the infrastructure without the help of third-party applications."
"The feature I like the most about Microsoft Defender for Office 365 is that it typically runs in the background—you do not know it is there until you need to access it."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
 

Cons

"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"Automation could be improved where you can easily add a TLS and SSL certificate to an application or web app if the developer did not include it."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"For the topic of improvement, providing some training material is one of my suggestions."
"I would like them to include a VPN feature to provide a secure connection to the data center."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"If you are not a technical guy, it is hard to maneuver, but as soon as you work on it, it gets better and better. If there was a better way to know how to do things or how to find things, it would be good."
"My opinion on the licensing of this solution is that it is a mess that needs sorting out. I am not particularly bothered by pricing as I administer it and make recommendations for people to buy or not to buy."
"In future releases, I would like to see two main improvements come to mind. First, the current solution requires maintaining two separate operating systems for FTD, which can be cumbersome. I'd love to see a single operating system for the FTD box."
"Scalability has certain shortcomings and needs to be improved because there are service providers who provide better scalability.v"
"The area of license renewal should be improved. We normally renew our license every year."
"The tool's pricing can be improved."
"The product's GUI for the dashboard needs improvement."
"While Cisco offers excellent solutions and innovations, the pricing may not be suitable for everyone. The cost of the software is relatively high. In the current market, there are numerous competitive alternatives that focus on security, enterprise networks, and various other aspects. Cisco, being a comprehensive provider, extends its expertise across data, servers, storage, and security, making them a preferred choice for many enterprises. However, when it comes specifically to security solutions, there are other vendors that specialize solely in this domain, offering competitive options."
"Microsoft Defender for Office 365 is not up to the mark in comparison with Wiz or Palo Alto."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"Too many false positives and lacks an accurate capability to detect malicious SharePoint sites."
"We need to be able to whitelist data at the backend."
"Sometimes I have to recategorize things when it takes the wrong step and I do not want it to classify something as suspicious."
"This product's effectiveness could be improved, in terms of detecting unwanted spam or even malware between the emails, compared to other products."
"You should be able to deploy Defender for every subscription without the need to add servers."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution is not that expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"The prices are slightly expensive."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"You're going to get what you pay for. If you're not willing to pay the price of Cisco, you're not going to get a product that's as good as Cisco. I don't think Cisco is overpriced, because for the last two years I've been comparing it to Microsoft and Cisco has been cheaper and given us more features."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"We were using Proofpoint and then we switched to Cisco... reportability was one of the main reasons we switched, but the biggest one was cost. If you can get an equivalent functionality for a better price it's wise to do so. That's what our primary decision came down to: We could get equivalent functionality at a lower price point."
"It is a reasonably priced solution."
"It is a relatively expensive option compared to other alternatives."
"The pricing for the Cisco Email Security Appliance involves recurring costs for licenses based on the contracted time frame, such as one year, three years, or five years. Renewals are required after the license expires."
"The product's price falls on the higher side when compared to the other products on the market."
"It is a super big router that costs a few hundred thousand dollars."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The license is expensive because the cost is based on the number of users."
"The product is very expensive."
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Top Industries

By visitors reading reviews
Construction Company
18%
Comms Service Provider
10%
Outsourcing Company
9%
Financial Services Firm
9%
Financial Services Firm
12%
Manufacturing Company
9%
Outsourcing Company
7%
Computer Software Company
7%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: August 2026.
907,787 professionals have used our research since 2012.