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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (9th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of July 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.5% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.2% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.1%, down from 12.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.1%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other87.5%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"The solution has different options that can be used to differentiate DDoS attacks."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"Cloudflare Access is a stable solution."
"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"Cloudflare Access is part of the Zero Trust philosophy."
"Enables me to work from two locations."
"This solution provides some benefits, like comfortable access to TAC support. You get prompt support when working directly with Cisco."
"Because we scan products, and there is a lot of critical data, security is very important in these cases."
"There were detailed logs available. That was a seriously good feature... It turns out these were actually spoof emails that came into our environment. I got to know about them from the log system."
"The user interface was quite friendly, it was quite easy to use, unlike some other Cisco products. Anybody could use it. You don't have to be familiar with IT to be able to handle navigating it."
"Administration of the email domains and custom filters are easily done via the web interface."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive."
"Cisco's Secure Email integrates with Cisco Firewalls, utilizing the AMP as their anti-malware engine, which allows for information sharing between devices."
"Cisco Secure Email's most valuable is email certification."
"My experience with customer support and technical support for Microsoft Defender for Office 365 has been excellent."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"The good part is that you don't have to configure it, which is very convenient."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"It gives us visibility into threats and, for endpoints, it helps us to prioritize threats. We used to have a lack of visibility, but now our time to detect and respond has decreased."
"Since we have started using the solution, there have been fewer compromises."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"Microsoft Defender for Office 365 has improved my organization's security. It makes it easier to manage the infrastructure without the help of third-party applications."
 

Cons

"For the topic of improvement, providing some training material is one of my suggestions."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"They don't have a person to provide support for customers using the solution under their free plan."
"Our customers no longer use Cloudflare because its service is subpar."
"The response time for support must be reduced."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"Automation could be improved where you can easily add a TLS and SSL certificate to an application or web app if the developer did not include it."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"The user interface of the Email Security Gateway should be improved."
"It would be nice to have an easier way to check on the health of the system, how stressed these appliances are. Sure, you can do it, but it would be helpful to have an easier way to do it, maybe even at a glance."
"They can do it better with web links, with the URLs. They have a technology called Outbreak but it doesn't work as well as we would like."
"There could be additional DLP functionality for it."
"Cisco is already providing a very good environment with the IronPort solution, but there could be some more integration with other products. For instance, an integration with the EDR solution could be there to raise an alert."
"The configuration UI should be made more intuitive. Currently, it takes a while to understand how to do the basic configurations."
"That's why I wouldn't give it anywhere near a perfect score, because the artificial intelligence just isn't there yet."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"There's room for improvement regarding the time frame for retrieving emails."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"We are waiting for better software to block viruses."
"Its price should be improved. Its cost is a major concern for us."
"We need to be able to whitelist data at the backend."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
 

Pricing and Cost Advice

"The solution is not that expensive."
"The solution's pricing lacks transparency."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The prices are slightly expensive."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"Cloudflare Zero Trust Platform's pricing is good."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The licensing was all transferred."
"The solution is expensive."
"Pricing depends on your environment and which model you want to buy."
"The pricing is good."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"It's adapted to the market. It's similar to other vendors. We at least don't have many problems regarding that because Cisco is adaptable on that side. When we present the solutions to the customers, we tend to achieve the goals that the customer has in terms of the budget for such implementations."
"I would rate the pricing a ten out of ten, where one is cheap, and ten is expensive."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"The pricing is normal. Considering its popularity, it's not overpriced."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The license is expensive because the cost is based on the number of users."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
7%
Outsourcing Company
7%
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: June 2026.
904,836 professionals have used our research since 2012.