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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.8
Reviews Sentiment
6.7
Number of Reviews
22
Ranking in other categories
Secure Web Gateways (SWG) (16th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (11th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (2nd), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (7th)
Microsoft Defender for Offi...
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of February 2026, in the Email Security category, the mindshare of Cloudflare One is 1.4%, down from 1.7% compared to the previous year. The mindshare of Cisco Secure Email is 5.1%, down from 7.1% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 9.1%, down from 13.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3659.1%
Cisco Secure Email5.1%
Cloudflare One1.4%
Other84.4%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It will take the blow rather than our applications should an attack occur."
"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"Cloudflare is by far the most effective solution that I have come across."
"Enables me to work from two locations."
"For Cloudflare Access, I am using the free plan...The most valuable feature is their protection."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"I'm very satisfied with the environment and the dashboard."
"I love the Advanced Malware Protection feature. It works very well... The appliance has more security such as SDF, DKIM, DMARC, and encryption."
"The technical support from Cisco is perfect."
"My favorite feature of Cisco Secure Email is the threat intelligence capabilities, particularly its integration with Cisco Talos."
"The filtering is definitely better at catching both spam and malicious messages, and there's a lot of extremely granular ability for setting up rules. You can do it the way you want to. The Microsoft solution tends to be pretty limited in how it allows some of that to be done."
"Cisco Secure Email is a budget-friendly solution."
"It's a bit easy to handle Cisco Secure Email; it's not that difficult. For the logs, which are in PDF format, it's not hard to read them. We don't need Wireshark much to analyze the logs."
"Cisco Secure Email has strong inbound services."
"The logs are easily readable and help diagnose problems, although they can be difficult to find initially. The solution addresses our email security, but for the rest of our security, we would use multiple vendors. It covers everything through email, like antivirus, IDS, and IPS."
"Since we have started using the solution, there have been fewer compromises."
"The product's scalability is good."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"The features I appreciate most about Microsoft Defender for Office 365 are admin notifications for potential threats along with protecting our Microsoft apps such as Outlook from potential phishing attacks."
"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"Some of the valuable features on the email side are anti-phishing, anti-malware, and Safe Links."
"The stability of Microsoft Defender for Office 365 is fantastic."
 

Cons

"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"Feedback could be enhanced."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"Our subscription plan for the solution has a limitation of bot signatures."
"Lacks a VPN feature to provide a secure connection to the data center."
"Cloudflare Zero Trust Platform needs to improve its documentation. It took time to do the implementation."
"In future releases, I would like to see two main improvements come to mind. First, the current solution requires maintaining two separate operating systems for FTD, which can be cumbersome. I'd love to see a single operating system for the FTD box."
"I would like them to add some clustering or high availability features."
"There could be additional DLP functionality for it."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"The user interface needs some improvement to become more user-friendly. The graphics could be better. It's designed more for a technical user rather than a business user."
"While Cisco offers excellent solutions and innovations, the pricing may not be suitable for everyone. The cost of the software is relatively high. In the current market, there are numerous competitive alternatives that focus on security, enterprise networks, and various other aspects. Cisco, being a comprehensive provider, extends its expertise across data, servers, storage, and security, making them a preferred choice for many enterprises. However, when it comes specifically to security solutions, there are other vendors that specialize solely in this domain, offering competitive options."
"It would be nice to have an easier way to check on the health of the system, how stressed these appliances are. Sure, you can do it, but it would be helpful to have an easier way to do it, maybe even at a glance."
"The UI is definitely one area of improvement because it doesn't match other interfaces and the navigation can be a little clunky."
"Too many false positives and lacks an accurate capability to detect malicious SharePoint sites."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"The pre-sales cost calculations could be more transparent."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"We still see many false positives from time to time with Microsoft Defender for Office 365, so it would be good if we can reduce those false positives and provide better workflows for our end users, as sometimes they may not know what to do when they encounter a false positive."
"Sometimes I have to recategorize things when it takes the wrong step and I do not want it to classify something as suspicious."
"The visibility for the weaknesses in the system and unauthorized access can be improved."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"Cloudflare Zero Trust Platform's pricing is good."
"The solution is not that expensive."
"The prices are slightly expensive."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The license was not per user, the license model was per feature. You could choose anti-virus, anti-spam, etc. It was feature-based and charged yearly."
"It is not that costly. We pay for the solution through a contractor and pay an annual fee."
"Licensing costs depend on how many users there are. It could range between $5 and $7 per month, per user."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
"I rate the product price as six on a scale of one to ten, where one means it is a very expensive tool."
"It is a super big router that costs a few hundred thousand dollars."
"The licensing was all transferred."
"The product is expensive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"The pricing is normal. Considering its popularity, it's not overpriced."
"The product is very expensive."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
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Top Industries

By visitors reading reviews
Computer Software Company
12%
Comms Service Provider
11%
Financial Services Firm
9%
Manufacturing Company
7%
Computer Software Company
16%
Manufacturing Company
9%
Financial Services Firm
8%
Comms Service Provider
6%
Computer Software Company
13%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise2
Large Enterprise10
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The user interface of the Email Security Gateway ( /products/security-gateway-reviews ) should be improved. It would ...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents...
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: February 2026.
882,479 professionals have used our research since 2012.