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Prisma Access by Palo Alto Networks vs ThreatLocker Zero Trust Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 17, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.0
Prisma Access enhances cybersecurity, offers cost-effective scalability, and streamlines services, providing financial benefits and operational efficiency.
Sentiment score
6.2
ThreatLocker enhances security, reduces costs, boosts productivity, and facilitates growth by blocking unauthorized applications and preventing malware.
There is a net positive return on investment
Network and Cybersecurity Consultant at a tech services company with 11-50 employees
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
Tier 1 IT Engineer at a retailer with 11-50 employees
Based on what we use ThreatLocker Zero Trust Endpoint Protection Platform for with the same functionalities and packaging, it was around 13 or 14 hours.
Head Of Cyber Security at a outsourcing company with 201-500 employees
We have the MDR package as well, and just knowing someone is watching those endpoints at 3:00 a.m. is a lifesaver that you cannot put a dollar figure on.
System Administrator at Gwynedd Mercy University
 

Customer Service

Sentiment score
6.7
Prisma Access support is praised for expertise but needs improvements in response time, support continuity, and language options.
Sentiment score
7.8
ThreatLocker Zero Trust Platform excels in customer support with quick resolutions, expert assistance, and effective live chat services.
The product is reliable, making customer support less frequently needed.
Senior DevOps Expert at Telenor
I usually need to raise the alarm and contact a couple of people within Palo Alto Networks to just respond quicker, so technical support should be much better.
Director at PULSEC
We rarely need to contact support due to having a strong internal team and a robust product.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
They have been very responsive, helpful, and knowledgeable.
Systems Security Analyst & Deputy Security Officer at a financial services firm with 201-500 employees
I would rate their customer support a ten out of ten.
Director, Managed Services at a consultancy with 11-50 employees
Their support is world-class.
Supervisor, Client Security at a consultancy with 11-50 employees
 

Scalability Issues

Sentiment score
7.4
Prisma Access is scalable for diverse companies but may face challenges in pricing and international deployment complexities.
Sentiment score
7.8
ThreatLocker Zero Trust Platform seamlessly scales across organizations, managing thousands of endpoints, ensuring performance, and easy user integration.
To scale, one would need to upgrade or acquire more hardware.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
Prisma Access provides significant scalability, allowing integration of different systems.
Senior DevOps Expert at Telenor
Prisma Access by Palo Alto Networks is a cloud-based solution, and from my experience, there are no issues with scalability.
Security Engineer at a tech services company with 1,001-5,000 employees
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
Technical Engineer at Cloud 1 Solutions
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
Systems Security Analyst & Deputy Security Officer at a financial services firm with 201-500 employees
ThreatLocker Zero Trust Endpoint Protection Platform scales very smoothly with our growing needs.
CEO at Mostro
 

Stability Issues

Sentiment score
7.9
Prisma Access is highly rated for stability, offering reliable performance with minimal issues and seamless scalability, despite minor delays.
Sentiment score
7.9
Organizations find ThreatLocker Zero Trust Platform stable and reliable, with minor issues quickly resolved by support.
I think the stability of Prisma Access by Palo Alto Networks is excellent, and I would rate it ten out of ten.
Security Engineer at a tech services company with 1,001-5,000 employees
Prisma Access by Palo Alto Networks works efficiently during peak usage times.
CyberSecurity Specialist at Aiuken
GlobalProtect is a satisfying solution, and the product is robust without major stability issues.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
For five years, we have not had a problem.
Supervisor, Client Security at a consultancy with 11-50 employees
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
Information Cybersecurity Technology Specialist at Freez.it
It has been very stable, reliable, and accessible.
COO at Panda Technology
 

Room For Improvement

Prisma Access needs better UI, integration, custom application support, pricing, documentation, global presence, and technical support enhancements.
Users seek improved training, integrations, transparency, UI, and communication in ThreatLocker Zero Trust Platform for enhanced usability and administration.
Hosting it in the cloud can mitigate these issues by allowing connection through the nearest Palo Alto or Prisma Cloud regional hub.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
There is a lack of integration with third-party solutions like CrowdStrike or SentinelOne in Prisma Access by Palo Alto Networks.
Security Engineer at a tech services company with 1,001-5,000 employees
Sometimes a third-party outage could impact the whole operability.
Network and Cybersecurity Consultant at a tech services company with 11-50 employees
Controlling the cloud environment, not just endpoints, is crucial.
COO at Panda Technology
ThreatLocker Zero Trust Endpoint Protection Platform could improve by being a little more hands-off, perhaps by having a team inside ThreatLocker that does all the vetting of patches; having one person hired by ThreatLocker to check out patches means that a million other industries using ThreatLocker Zero Trust Endpoint Protection Platform do not have to vet the same patch, ultimately saving time and money around the world.
Technical Support Engineer at CMIT Solutions of Central Orlando
This feedback would help us understand what is learned in real-time, especially during a one-hour learning mode setup, ensuring we remain aware of potentially unnecessary learned items.
Server Administrator at Clay County Sheriff's Office
 

Setup Cost

Prisma Access is costly but valued for its comprehensive security, with room for pricing and licensing flexibility improvement.
ThreatLocker Zero Trust Platform provides flexible, scalable pricing with tiered plans and negotiable deals, ensuring cost-effectiveness and transparency.
The pricing is on the higher side, rating it around eight to nine out of ten.
Senior DevOps Expert at Telenor
From my experience, Palo Alto is more expensive compared to solutions like Netskope and Triscale.
Security Engineer at a tech services company with 1,001-5,000 employees
Pricing for Prisma Access and Prisma SD WAN is high due to the need for different hardware flavors like IONs.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
Director, Managed Services at a consultancy with 11-50 employees
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
Supervisor, Client Security at a consultancy with 11-50 employees
Money is saved because it is not costly, and I would suggest it for other companies.
Helpdesk Engineer at Computer Network Infrastructure (CNI) Consultants
 

Valuable Features

Prisma Access provides scalable, secure cloud-based VPN access, real-time threat prevention, and integrates seamlessly with existing infrastructures.
ThreatLocker Zero Trust Platform excels in app control, security features, and support, enhancing IT efficiency and company security.
These features are security-driven, providing robust protection against increasing cyber threats by integrating NG Firewalls, SD WAN, and CASB, all within a fully cloud-native solution.
Senior DevOps Expert at Telenor
GlobalProtect has been beneficial for its cloud security capabilities, which are vital as businesses seek hybrid options and need to support remote workers while addressing latency issues.
Senior Manager for Infrastructure at a computer software company with 5,001-10,000 employees
One of the most valuable features of Prisma Access by Palo Alto Networks is the ability to manage on-premise firewalls.
Security Engineer at a tech services company with 1,001-5,000 employees
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
Cyber Security Specialist at Bremmar Consulting
It protects our customers.
CTO at Zettabytes
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.
Tier 1 IT Engineer at a retailer with 11-50 employees
 

Categories and Ranking

Prisma Access by Palo Alto ...
Ranking in ZTNA as a Service
4th
Average Rating
8.2
Reviews Sentiment
6.9
Number of Reviews
65
Ranking in other categories
Secure Web Gateways (SWG) (5th), Cloud Access Security Brokers (CASB) (1st), Enterprise Infrastructure VPN (5th), Secure Access Service Edge (SASE) (1st)
ThreatLocker Zero Trust Pla...
Ranking in ZTNA as a Service
5th
Average Rating
9.2
Reviews Sentiment
7.1
Number of Reviews
82
Ranking in other categories
Network Access Control (NAC) (4th), Endpoint Protection Platform (EPP) (5th), Advanced Threat Protection (ATP) (4th), Application Control (1st), ZTNA (5th), Ransomware Protection (1st)
 

Mindshare comparison

As of August 2026, in the ZTNA as a Service category, the mindshare of Prisma Access by Palo Alto Networks is 10.0%, down from 14.4% compared to the previous year. The mindshare of ThreatLocker Zero Trust Platform is 1.3%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
ZTNA as a Service Mindshare Distribution
ProductMindshare (%)
Prisma Access by Palo Alto Networks10.0%
ThreatLocker Zero Trust Platform1.3%
Other88.7%
ZTNA as a Service
 

Featured Reviews

IgorPinter - PeerSpot reviewer
Director at PULSEC
Zero-trust access has improved remote security and now simplifies cloud-based firewall management
Regarding the integration part for Prisma Access by Palo Alto Networks, the integration with identity providers is pretty much good. It is basically firewall as a service, so it performs well. I completed the integration without any issues. What Palo Alto Networks can do better for Prisma Access by Palo Alto Networks is probably to have the point of presence available in more locations. The point of presence from the Serbia region has the nearest POP in Frankfurt, which is an issue since it is your gateway—when you start browsing the internet, you go through a commercial connection in Germany. They definitely need to spread the service in other countries.
Santo Joy - PeerSpot reviewer
Head Of Cyber Security at a outsourcing company with 201-500 employees
Security controls have been strengthened with granular application, ringfencing, and access policies
The features of ThreatLocker Zero Trust Endpoint Protection Platform that I like the most are the Ringfencing, elevation control, storage control, and application whitelisting functionality. For examples of how these features benefit my company, we were looking for a solution across various vendors to actually implement application whitelisting controls. ThreatLocker's agent, which is very lightweight and does not use much CPU or RAM, helped us achieve that solution. Ringfencing was an add-on that ticked off a lot of Australian framework security controls, which is the reason we chose it. My impression of the allowlisting feature in terms of managing which software, scripts, and libraries run on my devices is that ThreatLocker's community page has a lot of information around this, which is very helpful. Not only that, the Cyber Hero support that ThreatLocker provides gives us insights and best practices, helping us achieve that solution and guiding us to the right platform. The impact of Ringfencing on controlling the behavior of approved applications has been a big winner for us because it is something that many other platforms do not provide as a functionality. Having that allowed us to identify what applications talk to each other, which is something that many other platforms do not do. The network control feature impacts my ability to manage network traffic across my endpoints and servers. We have not used this widely across all our partners, but wherever required, we use it. It has been an easy solution for those customers to get that control implemented. The elevation feature's role in facilitating just-in-time administrative access for approved applications shows that elevation control helps in many use cases involving remote control platforms, door usage, and security system platforms that require local admins. There are many solutions that provide this functionality, but the licensing cost seems to be expensive, and it also adds another solution into the mix. Rather than doing that, we try to use ThreatLocker Zero Trust Endpoint Protection Platform to achieve that control. Regarding the storage control feature, I have used it. The primary function is USB blocking, which is very widely adopted, and also just locking down and allowing certain users to access certain file locations helps us there. When it comes to enforcing policy-driven access over various storage devices, it depends on the business risk adapted by the companies that we support, but generally the use case is USB and external storage devices where companies know that is a risk, but they do not have appropriate solutions. There are EDR platforms that claim to do this, but ThreatLocker Zero Trust Endpoint Protection Platform does it at an advanced level. My assessment of the efficiency of the real-time threat intelligence and category controls employed by Web Control in blocking malicious and non-compliant sites leads me to think that Web Control is another functionality within ThreatLocker Zero Trust Endpoint Protection Platform that is an add-on on top of the current set. That is another solution that we use based on what is required for the company, but again, that is not widely adapted yet for our partners.
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Top Industries

By visitors reading reviews
Financial Services Firm
12%
Manufacturing Company
10%
Computer Software Company
8%
Outsourcing Company
6%
Computer Software Company
11%
Financial Services Firm
11%
Manufacturing Company
11%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business26
Midsize Enterprise20
Large Enterprise27
By reviewers
Company SizeCount
Small Business56
Midsize Enterprise14
Large Enterprise13
 

Questions from the Community

What is the better solution - Prisma Access or Zscaler Private Access?
We looked into Prisma Access before choosing Zscaler Private Access (ZPA). Palo Alto’s Prisma Access is a secure access service edge (SASE) designed to deliver network security in a cloud-deliver...
What is your experience regarding pricing and costs for Prisma Access by Palo Alto Networks?
From my experience, Palo Alto is more expensive compared to solutions like Netskope and Triscale.
What needs improvement with Prisma Access by Palo Alto Networks?
Regarding the integration part for Prisma Access by Palo Alto Networks, the integration with identity providers is pretty much good. It is basically firewall as a service, so it performs well. I co...
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
My experience with pricing, setup cost, and licensing for ThreatLocker Zero Trust Platform is that the pricing is reasonable, the cost is fair, and the licensing is not too high.
What needs improvement with ThreatLocker Allowlisting?
I would suggest adding an AI-based policy recommendation feature to ThreatLocker Zero Trust Platform because we have to create every policy manually. If there were a custom AI that could help with ...
What is your primary use case for ThreatLocker Allowlisting?
Our main use case for ThreatLocker Zero Trust Platform is to provide endpoint security and to control each and every application end-to-end that can run on the company's devices, primarily to secur...
 

Also Known As

Palo Alto Networks Prisma Access, Prisma Access, GlobalProtect, Palo Alto GlobalProtect Mobile Security Manager, Prisma SaaS by Palo Alto Networks, Prisma Access
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

Concord Hospital, State of Colorado, Essilor International, RheinLand Versicherungsgruppe, University of Westminster, Universidade Nove de Julho, SPAR Austria, CAME Group, ZipRealty, Greenhill & Co., IKT Agder, Aviva Stadium, Animal Logic, Management & Training Corporation, Brigham Young University Hawaii, School District of Chilliwack
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