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Microsoft Defender for Office 365 vs Trend Micro InterScan Messaging Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Email Security
1st
Ranking in Secure Email Gateway (SEG)
1st
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
53
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th)
Trend Micro InterScan Messa...
Ranking in Email Security
34th
Ranking in Secure Email Gateway (SEG)
14th
Average Rating
7.0
Reviews Sentiment
7.1
Number of Reviews
3
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of October 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 11.4%, down from 14.8% compared to the previous year. The mindshare of Trend Micro InterScan Messaging Security is 0.6%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 36511.4%
Trend Micro InterScan Messaging Security0.6%
Other88.0%
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Abdul  Waris - PeerSpot reviewer
Deploy features like DLP and BEC for enhanced security
Multiple clients are using email security. We provide solutions based on what they need, and we configure them accordingly as per the requirement With Trend Micro email security gateway, we can deploy features like DLP and BEC. It includes Office 365 protection and sandboxing. This provides…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The deployment capability is a great feature."
"My experience deploying Microsoft Defender for Office 365 was seamless."
"Scalability-wise, I do not think there are any issues so far."
"The DLP feature of Microsoft Defender for Office 365 is valuable, and we also use the DLP feature for email real-time detection."
"It has significantly decreased my time to detection and response."
"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."
"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"My experience with customer support and technical support for Microsoft Defender for Office 365 has been excellent."
"The solution provides protection with its Email Track Records and Machine Manual features."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
"The technical support services are excellent."
 

Cons

"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"We need to be able to whitelist data at the backend."
"The product's pricing could be more flexible."
"The solution's pricing could be improved."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
 

Pricing and Cost Advice

"The pricing is normal. Considering its popularity, it's not overpriced."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The product is expensive."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"The product is very expensive."
"Trend Micro is an expensive solution."
"I rate Trend Micro InterScan Messaging Security’s pricing a seven out of ten."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Performing Arts
14%
Manufacturing Company
11%
Financial Services Firm
10%
Computer Software Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise8
Large Enterprise27
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download. VirusTotal helps to identify viruses, malware, troja...
What is your experience regarding pricing and costs for Trend Micro InterScan Messaging Security?
The price is a bit high because the market is highly competitive. Multiple platforms are available, so we have to choose based on comparison.
What needs improvement with Trend Micro InterScan Messaging Security?
There is room for improvement in content filtration, expressions, file sharing, and policy configuration. We could decrease the price in email security gateway and cloud security services.
 

Also Known As

MS Defender for Office 365
InterScan Messaging Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Copa Airlines, Air21, BookMyShow, Bulgarian American Credit Bank, Canadian Museum of History, CIBIL, Community National Bank, Dar Al-Handasah
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trend Micro InterScan Messaging Security and other solutions. Updated: September 2025.
869,202 professionals have used our research since 2012.