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Cisco Secure Email Threat Defense vs Trend Micro Deep Discovery Email Inspector comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
Trend Micro Deep Discovery ...
Ranking in Email Security
26th
Average Rating
7.8
Reviews Sentiment
7.1
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of Trend Micro Deep Discovery Email Inspector is 0.4%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Bilal Saleem - PeerSpot reviewer
Reliability and threat intelligence make this solution competitive, but AI improvements can further enhance its effectiveness
The best features of Trend Micro Deep Discovery Email Inspector include its reliability. The second valuable feature is its built-in sandbox feature, allowing for inspection of incoming emails and attachments. The sandbox is an appliance that opens any attachment in an enclosed environment to assess its impact and potential for viruses. This protects the network from harmful threats. Trend Micro has a very large R&D team with excellent threat intel, allowing them to provide better solutions than some competitors. They understand emerging threats based on the information from their EDR. The key strengths can be summarized as reliability, a good integrated one-box solution that includes a sandbox, and their R&D capabilities and good ratings, which lead to better threat intelligence. The detailed threat intelligence provided by Trend Micro Deep Discovery Email Inspector is valuable in understanding the behavior and tactics of potential email threats.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The product's scalability is good."
"Does a thorough job of examining email and URLs for malicious content."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"The DLP feature of Microsoft Defender for Office 365 is valuable, and we also use the DLP feature for email real-time detection."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"The stability of Microsoft Defender for Office 365 is fantastic."
"It also gives the vulnerability status according to the versions you have selected. Let's say you have Google Chrome. It mentions the versions it has, and it updates. Within two hours of an update, it is reflected in the dashboard. That's really nice to have."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"It's very easy to deploy and configure."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"This solution is easy to use."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"The product offers protection, email security, anti-spam, and antivirus."
"Secure Email Threat Defense's scalability is good."
"It has an efficient email filtering feature."
"The best features of Trend Micro Deep Discovery Email Inspector include its reliability."
"I like that it is very user-friendly and easy to install."
"The solution's most valuable features include visibility into the network and fast sandboxing technology for alerts, though response time can vary."
"It can effectively monitor outbound and inbound devices."
"Trend Micro is a very good product."
"I would rate the solution's stability at ten out of ten."
"I find Trend Micro to be a good solution for security purposes."
"I highly recommend Trend Micro Deep Discovery Email Inspector due to its security and scalability features."
 

Cons

"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"We need a separate license and we don't know how to get the license that is required."
"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats. For example, information about best practices on how to protect their own devices against hackers and scammers, such as educational information or training. This would help others have a better understanding of cyber security. Additionally, there can be more security features added."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"The changes to customer service, specifically the new model for support agreements, are not favorable."
"The solution is a bit expensive."
"The pricing could always be better."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"We encounter issues while searching for missing emails."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The tool needs to incorporate faster response times for issue detection, more detailed reports, and better compatibility with older operating systems (e.g., Windows 7, 8, Server 2012)."
"I would like to be able to send emails to a specific sandbox. This is a feature I would like to see added to the next release."
"The dashboard could be improved to match the quality of Check Point Harmony's dashboard."
"To improve Trend Micro Deep Discovery Email Inspector, it should have updates with better AI and ML-based integration."
"Trend Micro's technical support has room for improvement. More efficient support should be provided, especially for standard support."
"It could be more user-friendly, easier to install, and lighter on the network. I would say that for all products because you do not need technical expertise to take care of it. When you have a user-friendly solution, it makes it easier for the vendors or companies like us. We do not have to go to the client's site to attend to issues all the time. Because it is user-friendly, they can take care of it after some training."
"Trend Micro's technical support has room for improvement."
"Trend Micro Deep Discovery Email Inspector could improve by making it easier to use. Microsoft solutions are easier to use."
 

Pricing and Cost Advice

"It's a user-base subscription."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The pricing has become expensive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The license is expensive because the cost is based on the number of users."
"The pricing is normal. Considering its popularity, it's not overpriced."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"We pay for an annual subscription for this email security solution."
"The solution's pricing is high, and I would rate it an eight out of ten."
"It's an expensive solution, and you may not see a return on investment in a short period of time. However, you will see a return over a long period of time."
"The price of Trend Micro Deep Discovery Email Inspector is less expensive than Microsoft solutions."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
29%
Healthcare Company
7%
Government
6%
Manufacturing Company
6%
Computer Software Company
14%
Financial Services Firm
13%
Performing Arts
9%
Media Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is your experience regarding pricing and costs for Trend Micro Deep Discovery Email Inspector?
On the pricing side, Trend Micro Deep Discovery Email Inspector is not the cheapest, but it's not the highest either....
What needs improvement with Trend Micro Deep Discovery Email Inspector?
To improve Trend Micro Deep Discovery Email Inspector, it should have updates with better AI and ML-based integration...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Deep Discovery Email Inspector
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Bank Saint Petersburg, CEITEC S.A., Dar Al-Handasah, Mitsubishi Electric Information Systems, Motilal Oswal Financial Services Ltd, OKWAVE, Oman Arab Bank, VakifBank
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trend Micro Deep Discovery Email Inspector and other solutions. Updated: June 2025.
858,469 professionals have used our research since 2012.