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Cisco Secure Email Threat Defense vs Kiteworks comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
Kiteworks
Ranking in Email Security
32nd
Average Rating
8.6
Reviews Sentiment
6.9
Number of Reviews
13
Ranking in other categories
Enterprise Content Management (15th), Managed File Transfer (MFT) (7th), Content Collaboration Platforms (14th), Secure Email Gateway (SEG) (11th)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of Kiteworks is 0.3%, up from 0.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Sukkanta Banerjee - PeerSpot reviewer
Two-factor authentication and .ZIP format make large file transfers very secure
The most valuable feature is the ability to send a large file of 30 GB in size and more. In Outlook and other email applications, you cannot send files that are larger than 20 MB. But with Kiteworks, 30 GB is transferable by default and, with the proper approval, a file of up to 100 GB can be sent. It makes file transfer very easy and smooth. Also, only the .ZIP format is supported because it is a very secure mode of file transfer, and that is why it is recommended. It also has built-in antivirus, so if it detects any malware it will quarantine the file and it won't be delivered. This is really important to keep the service up and running in a proper and secure manner. With people working from home, the data needs to be checked to see what kind of data is being sent. It has a two-factor authentication mechanism. For example, if a person with a particular domain is using Kiteworks and sends a file to a party outside of his domain, that external party has to go through two-factor authentication. The receiver gets a link that takes them to the setup of a temporary account, which will be valid for three days. The recipient will also receive a customized password separately. Only after all these steps will they be able to access the file. That access is only available to a person with the mail ID to which the file was sent. In addition, admins can see who is sending sensitive content, what that content is, and to whom it is being sent, and can track emails. One week of good training will give a user complete knowledge for using the solution. The system is very easy to use. You just click on "Compose," attach a file, and send it. It's very easy compared to Outlook or Teams. It's quite simple, even for someone logging in for the first time. It is very smooth and easy to send files.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"The deployment capability is a great feature."
"The ability to respond to threats if very important."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"Scalability-wise, I do not think there are any issues so far."
"We use Microsoft Defender for its ability to integrate with existing business technologies, which is beneficial for protecting business areas."
"Defender is a SaaS platform, so it offers more flexibility. Managing the permissions is easier. The solution's automated detection and response features are scalable."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"The solution is stable."
"Secure Email Threat Defense's scalability is good."
"This solution is easy to use."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"Scalability is impressive."
"The benefits that Kiteworks has provided to its customers in terms of data sovereignty."
"The most valuable aspect of Kiteworks is undoubtedly the private content network. This feature is particularly beneficial for us. Furthermore, it serves as a centralized platform that enables us to track and manage our information exchange."
"I can identify from which region our users are uploading or downloading files."
"The best part of this solution is that we can generate multiple reports about how the data is transferred and about user information or IP."
"The top two features are the two-factor authentication, which is pretty good. It's easily understood by the users. And their API is rather robust. We have numerous integrations that work off the API."
"We could see whether the customer with whom we shared a file had downloaded it, which was not available with GitHub."
"We can see when people are sending things. We can definitely see who is sending to whom. From the administrative logs, we can see who is sending to an outside entity, and those logs are retained for quite a while."
 

Cons

"Several simulation options are available within 365, and the phishing simulation could be better."
"The custom alerts have to improve a lot."
"The UI needs to be more user-friendly."
"The product must provide better malware detection."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"The pricing could always be better."
"The physical appliance has been discontinued, although the platform still exists."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"This solution could be improved by integration with Sandbox."
"We encounter issues while searching for missing emails."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The solution is a bit expensive."
"Kiteworks could benefit from enhancing the proposal knowledge base section, specifically regarding the type of work involved. Currently, the knowledge base seems insufficiently dedicated to this topic, making it challenging for new users to access the relevant administrative law. Improving the visual aids and providing clearer explanations could alleviate this issue."
"File location could be improved."
"There are always issues when there are bugs or upgrades. The challenge with upgrading is getting more storage from the customer. Every time we have a new version, it requires additional storage. This means that the customer would need to procure more storage for their server, which they don't like because it means additional cost to them. So, I think my request would be that the version upgrades don't require any significant storage requirement."
"I would like to see immediate releases of fixes because now it takes at least a week. If that time span can be reduced to one day or two days, that would be very helpful for users so that things are sorted and transactions work smoothly."
"I noticed the Kiteworks login UI is very basic, lacking customization. Allowing more HTML tags to add hyperlinks or user-friendly information on the home page would be very useful."
"Perhaps there could be a notification to users about their bandwidth or network packet loss."
"It would be nice if Kiteworks could provide a free version of the platform so that it could be used for a certain number of file transfers. We could be charged a fee if we exceeded the number of allotted file transfers."
"It could be more stable. In the next release, it would be better if it was more stable with improved performance."
 

Pricing and Cost Advice

"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"The product is expensive."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The pricing has become expensive."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The license management is changing and confusing. If I could make one change to it, it would be better license management through the API."
"I believe it's a little costly, but given the faith that we put into it from a security perspective to maintain the integrity of our patient information that is being transferred through this system, that's a small price to pay. So, on the surface, it might look like a lot of money, but depending on the need for security, which is where we feel it shines, it's okay price-wise."
"The price of Kiteworks is reasonable."
"The solution is very expensive because we are buying with Malaysian Ringgit and it's sold in US dollars."
"They changed it midstream. We were being charged a certain flat rate for SFTP traffic. For whatever reason, at the beginning of the year, our pricing changed, and we are now being charged more for using a feature of the product than we were when we first bought it. That has been our experience with billing. It turned out to be more expensive than when we started with it."
"It is not really expensive. I mean, to me it's obviously expensive, but it's worth it."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
30%
Government
7%
Healthcare Company
7%
Financial Services Firm
5%
Government
15%
Financial Services Firm
13%
Manufacturing Company
7%
Computer Software Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is Kiteworks?
Kiteworks is a secured file sharing platform that enables users to collaborate with different parties across a robust...
What do you like most about Kiteworks?
The benefits that Kiteworks has provided to its customers in terms of data sovereignty.
What needs improvement with Kiteworks?
I'm not a network expert, however, there must be some room for improvement. Perhaps there could be a notification to ...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Accellion
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
United States Securities and Exchange Commission, National Health Service, Husch Blackwell LLP, NYC Health + Hospitals, Viatris, MITRE Corporation, Chubb, Kraft Heinz, KPMG, Kohler, National Institute of Standards and Technology, Purdue Pharma, AVL
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Kiteworks and other solutions. Updated: June 2025.
856,873 professionals have used our research since 2012.