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Cisco Secure Email Threat Defense vs Proofpoint Email Protection comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
22nd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Proofpoint Email Protection
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
110
Ranking in other categories
Advanced Threat Protection (ATP) (5th), Digital Risk Protection (5th), Office 365 Protection (1st), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of November 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Proofpoint Email Protection is 5.9%, down from 7.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Proofpoint Email Protection5.9%
Cisco Secure Email Threat Defense1.1%
Other93.0%
Email Security
 

Featured Reviews

GC
Senior Cybersecurity Engineer at a financial services firm with 11-50 employees
Provides robust email security features but requires improved modernization and complexity management
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilities. The initial setup is not straightforward and requires expertise and time to master configurations such as spoofing and DLP. More control over backend functionalities and simplifying rule management could enhance user experience. The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration. Furthermore, the pricing might deter new users who could opt for alternative, more cost-effective solutions.
Siva_Prasad - PeerSpot reviewer
Senior Consultant at a tech vendor with 10,001+ employees
Email defenses have reduced phishing incidents and protect sensitive data across our enterprise
As things are evolving and threats develop in unpredictable ways, Proofpoint must adopt AI solutions and agentic solutions more aggressively and provide them to customers as part of service offerings. Inbuilt AI solutions would add more value and make Proofpoint a more premium choice for customers. With the help of AI solutions, agentic AI, and generative AI capabilities, the product would be more efficient than it currently is. Filtering false positives is highly challenging because it is impossible for humans to identify which emails are genuine and which are spam. Proofpoint should focus more on this area with back-end agents or other tools. Proofpoint should decide which emails are genuine and which are spam so it is not a challenge for end users. When receiving an email, end users should not have to determine whether to respond or not. Proofpoint should not release such spam emails and should strictly block such spam and spoof emails based on connection IPs. Currently, false positives occur in the product, and while this occurs in every product, it is an area where Proofpoint can focus on improving and reducing false positives. One email is enough for an end user to be deceived and lose money, so addressing this area is critical.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It's very easy to deploy and configure."
"It has an efficient email filtering feature."
"The product offers protection, email security, anti-spam, and antivirus."
"Cisco Cloud Mailbox is used for copying emails, anti-spamming, and securing the company's email, and we really enjoy the anti-spamming capabilities as well as the rejecting of bulk emails, which we can customize by adjusting the variables, and it is very user-friendly."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"I highly recommend it as one of the best choices."
"On ease of use, it rates very high."
"This solution is easy to use."
"Using Proofpoint Email Protection has successfully reduced the volume of emails that we need to review."
"Proofpoint Email Protection's detection for true positives are great, false negatives or type two errors are very low, type one errors are acceptable and this capability is the one that allows the least amount of spam to enter."
"The solution's technical support is good. I rate the technical support a ten out of ten."
"The most valuable feature of Proofpoint Email Protection is the TAP Dashboard. It provides more detailed information that can be used for forensic analysis. This is an advantage that other email security providers, such as Cisco, IronPort, or Microsoft do not offer in their dashboards."
"Proofpoint Email Protection provides visibility into people-based risk within my organization, and I am able to see which users have a higher risk rate."
"Proofpoint Email Protection has positively impacted my organization by blocking significantly more phishing emails, and phishing is the main entry point into getting compromised, so I have more peace of mind knowing that more malicious emails are getting blocked."
"Provides better control over emails, especially those sent via Office 365 on the cloud."
"The targeted attack protection that we use has been great, as has the email filtering and the rules that we have set for Proofpoint."
 

Cons

"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The physical appliance has been discontinued, although the platform still exists."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"I wouldn't recommend Cisco to others because I think Fortinet is better."
"The solution is a bit expensive. It could be cheaper."
"I remember having multiple tickets and cases from customers where when a link was broken or incorrect, URL Defense would start to apply and completely block the URL."
"The initial setup is complex."
"The downside is I feel the vendor support is a little lacking and should be more responsive."
"Some of the old portal features of Proofpoint Email Protection are missing in the new portal, so some of the settings could be modernized."
"The incident reporting on offer needs to be improved. It's lacking right now. It should be on the platform somewhere."
"Phishing detection could improve further to match some of the capabilities offered by competitors."
"My experience with pricing, setup cost, and licensing for Proofpoint Email Protection is that it is somewhat on the higher end and more premium, but it is a good product."
"I would want better spear phishing protection in the essentials package."
 

Pricing and Cost Advice

"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"We sell annual licenses for this solution."
"The solution is expensive."
"I rate the price of Proofpoint Email Protection a four out of five."
"Proofpoint Email Protection is a reasonably priced product, which means that it is neither too low nor too high in terms of price."
"The solution uses a licensing model that is reasonable compared to other products."
"Proofpoint Email Protection has comparable pricing."
"Proofpoint is fairly expensive."
"Annually, it costs us about $92,000. This is pretty much what it costs us. There is no additional cost."
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Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Outsourcing Company
9%
Comms Service Provider
9%
Healthcare Company
9%
Financial Services Firm
13%
Outsourcing Company
10%
Manufacturing Company
10%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise23
Large Enterprise62
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with Proofpoint Email Protection?
To improve Proofpoint Email Protection, I suggest breaking down the URL into one versus three different GUIs. Regarding Proofpoint Email Protection's AI capabilities, I think its governance and sec...
What is your primary use case for Proofpoint Email Protection?
My main use case for Proofpoint Email Protection includes phishing emails, spam, URL isolation, and training. I utilize the email protect portal to ensure that none of our employees in any of the b...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Proofpoint Enterprise Protection, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Proofpoint Email Protection and other solutions. Updated: November 2026.
920,939 professionals have used our research since 2012.