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Cisco Secure Email vs Cisco Secure Email Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email
Ranking in Email Security
3rd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
62
Ranking in other categories
Cisco Security Portfolio (7th)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email is 6.4%, down from 8.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Kostas Karidas - PeerSpot reviewer
Helps prevent security breaches but fails to improve in the area of AI
I have not noticed any impressive advanced threat protection mechanisms in the tool. I don't know if there are any AI features in the product. I don't know if there is any other technology embedded in the solution. Cisco Secure Email successfully mitigated potential email threats. My company has seen plenty of scenarios where Cisco Secure Email successfully mitigated potential email threats, spam emails, and fraudulent domains. The product is good for dealing with spam emails, and it can take care of more than 100 spam emails per day. A huge number of spam emails are monitored with the help of Cisco Secure Email. I would not recommend the product to other businesses because you need to have some kind of expertise in configuring and knowing a bit about the tool's GUI. The tool also lacks in the area of AI mechanics. If I would like to have an overview and review another solution, I would go for another product other than Cisco Secure Email. I can definitely suggest others to look at the product and review it, but I would also recommend that they compare it with the other solutions in the market. I wouldn't prioritize Cisco Secure Email over other tools. Either the support partner of the product or I take care of the tool's maintenance phase by looking into the configurations and doing some fine-tuning. I rate the tool a seven to eight out of ten.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The technical support is good and quick to resolve issues."
"Microsoft Defender for Office 365 helps people to work remotely. It is a secure solution. We don't need to use our company's computers or get VPN connections to the networks. I can control how they share screens and what they send to the devices. It keeps our organizations confidential and sensitive information safe."
"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"The ability to respond to threats if very important."
"Since we have started using the solution, there have been fewer compromises."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive. Previously, our users had to deal with nine million additional emails across the organization, which is nearly 1,000 emails per user to have to deal with a month. That's a massive amount for our staff to deal with and probably several hours of their time. We have a lot of clinical staff, being a hospital. We want to make our staff as productive as possible. By removing a lot of that spam and phishing type emails, this allows them to do their job."
"The technical support from Cisco is perfect."
"The security features are valuable."
"What I find the most valuable about Cisco Secure Email is that the logs are not that difficult to see even if you're not used to them. The logs are reasonably readable and diagnosing the problem is not too hard with them."
"The added value of it is that every migration to a new version is initiated by the Cisco version itself, so that is a bunch of work that you don't have to do on the Cisco ESA system on-premise. As it becomes a safe platform, you don't need to invest anything in your own data center or in your upgrade path."
"The product blocks spam emails."
"The product's initial setup phase was easy."
"The logs are easily readable and help diagnose problems, although they can be difficult to find initially. The solution addresses our email security, but for the rest of our security, we would use multiple vendors. It covers everything through email, like antivirus, IDS, and IPS."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Secure Email Threat Defense's scalability is good."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The solution is stable."
 

Cons

"The product must provide better malware detection."
"You should be able to deploy Defender for every subscription without the need to add servers."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"Too many false positives and lacks an accurate capability to detect malicious SharePoint sites."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"The custom alerts have to improve a lot."
"Cisco Secure Email can be improved from the administrator's point of view. Usually, you have to work with different areas, and they can try to make it easy for the administrator to use different functions."
"The configuration UI should be made more intuitive. Currently, it takes a while to understand how to do the basic configurations."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"The product's GUI for the dashboard needs improvement."
"I would like them to add some clustering or high availability features."
"We cannot manage multiple devices from a single UI."
"The area of license renewal should be improved. We normally renew our license every year. There is a feature called smart licensing, and I switched from the legacy mode to the smart licensing mode because of what I thought smart licensing does. I thought it would make licensing renewal seamless and very swift, but ever since I've switched to smart licensing, each time I want to renew my license, it is a whole lot of headache. The process is not smooth, and I had to keep calling Cisco TAC to see how the issue can be resolved. At one point, I wanted to revert back to the legacy mode, but I can't revert. Once you switch from the legacy mode to the smart licensing mode, you can't revert. They should improve on the visibility of the smart licensing mode so that it can indeed be smart and easier to use for the license renewal every year. That is one challenge."
"The solution is a bit expensive."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The pricing could always be better."
"We encounter issues while searching for missing emails."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"This solution could be improved by integration with Sandbox."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
 

Pricing and Cost Advice

"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The pricing has become expensive."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"The solution is expensive."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"It is a reasonably priced solution."
"It is a super big router that costs a few hundred thousand dollars."
"In my previous organization, avoiding four instances of CryptoLocker within an estimated six month period is approximately $600,000 in lost time and effort. Our five year cost was about a million dollars, and the four outages that we had equated to 65 percent of that five year cost."
"Cisco Secure Email is more expensive than other products. I rate it a five out of ten. There are no additional costs. You only need to pay the subscription amounts."
"It is a relatively expensive option compared to other alternatives."
"The solution’s pricing is manageable."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Educational Organization
24%
Computer Software Company
18%
Financial Services Firm
8%
Manufacturing Company
5%
Computer Software Company
30%
Government
7%
Healthcare Company
7%
Financial Services Firm
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The user interface of the Email Security Gateway ( /products/security-gateway-reviews ) should be improved. It would ...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
 

Also Known As

MS Defender for Office 365
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Find out what your peers are saying about Cisco Secure Email vs. Cisco Secure Email Threat Defense and other solutions. Updated: June 2025.
856,873 professionals have used our research since 2012.