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Cisco Secure Email Threat Defense vs Trellix Collaboration Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
27th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Trellix Collaboration Security
Ranking in Email Security
18th
Average Rating
8.6
Reviews Sentiment
7.0
Number of Reviews
15
Ranking in other categories
Instant Communications Security and Compliance (4th), Secure Email Gateway (SEG) (8th)
 

Mindshare comparison

As of October 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 0.9% compared to the previous year. The mindshare of Trellix Collaboration Security is 1.8%, down from 2.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Trellix Collaboration Security1.8%
Cisco Secure Email Threat Defense1.1%
Other97.1%
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
BernardLugalia - PeerSpot reviewer
Provides strong data protection with virtual patching and vulnerability assessments
I primarily use it to monitor database access, particularly in banking and similar environments. It ensures that IT personnel and others do not create unauthorized accounts or users. Collaboration security assists in tracking database access and alerts in case of suspicious activity One of the…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"This solution is easy to use."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"The advanced threat analytics and URL filtering in threat detection are good features that are working well."
"The product offers protection, email security, anti-spam, and antivirus."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"Trellix Collaboration Security is valued for being a stable and comprehensive solution that fulfills customer needs."
"The product protects my email."
"We can control this solution from the cloud and are able to access it from wherever we are."
"The solution's most valuable feature is its simplicity. It's very user-friendly."
"FireEye Email Security helps us prevent spam and phishing emails and all other business-compromised email attacks."
"FireEye Email Security is easy to use."
"The initial setup is simple."
"We have had very good results from the use of FireEye Email Security. We are very comfortable with this technology, but I don't know if it's necessary to move into the cloud, we will check other technologies and study them. Additionally, the solution has good integration."
 

Cons

"The solution is a bit expensive."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"The physical appliance has been discontinued, although the platform still exists."
"We encounter issues while searching for missing emails."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"Sometimes especially zero-day spam emails can be passed to the user's inbox."
"I would like the solution to be able to automatically quarantine the malicious emails before getting to the user's mailbox and continue with regular email operations. This could result in the user clicking the email before the purge operation is completed."
"There is a need for improved integration with totally different products, such as a rapid server."
"If they want to be the primary or best solution, they need to have better email management features."
"The solution must provide features to scan QR codes for threats."
"The solution is not easy to set up. However, we have employees that have the knowledge that can do the difficult implementation. It would be better if the process was easier."
"Sometimes, integration can be challenging, impacting its stability, which is why I rate it a five out of ten."
"FireEye needs single sign-on. They say it's on their roadmap. They should also implement support for Microsoft Authenticator app for 2FA."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"I rate the product price as nine out of ten, where ten is the most expensive, and one is the cheapest. There is no need to pay any extra charges apart from the licensing costs."
"The solution requires a license to be purchased for every user."
"The licensing is on a yearly basis."
"The cost is very high."
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Top Industries

By visitors reading reviews
Computer Software Company
20%
Manufacturing Company
8%
Healthcare Company
8%
Government
7%
Manufacturing Company
18%
Comms Service Provider
11%
Computer Software Company
10%
Government
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business6
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What do you like most about FireEye Email Security?
One of the valuable features of the product stems from the fact that it is easy to implement the tool in our environment.
What needs improvement with FireEye Email Security?
I would like to see the addition of email digital protection features, such as anti-spam and antivirus, not just sandboxing, in the on-premises solution.
What is your primary use case for FireEye Email Security?
I have worked on Email Security ( /categories/email-security ) both on-premises and in the cloud, Web Security, and also on MDR, which is called HX endpoint security for Trellix Collaboration Secur...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
FireEye Email Security
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trellix Collaboration Security and other solutions. Updated: September 2025.
869,513 professionals have used our research since 2012.