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Cisco Secure Email Threat Defense vs Trellix Collaboration Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
23rd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Trellix Collaboration Security
Ranking in Email Security
12th
Average Rating
8.8
Reviews Sentiment
6.9
Number of Reviews
21
Ranking in other categories
Instant Communications Security and Compliance (2nd), Secure Email Gateway (SEG) (7th), AI Security (14th)
 

Mindshare comparison

As of August 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Trellix Collaboration Security is 2.4%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Trellix Collaboration Security2.4%
Cisco Secure Email Threat Defense1.1%
Other96.5%
Email Security
 

Featured Reviews

NM
Enginner at Millennium Information Technologies
Has faced challenges with configuration, taking actions, and learning curve but benefits from centralized management and good technical support
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, are limited as ETD only supports sending audit logs. Customers have requirements for other system logs as well, which should be developed from their side. Another customer request is to restrict the IPs that can log in, which cannot be done from Cisco Secure Email Threat Defense yet. Any user with login details can log in. We can restrict the IPs in Cloud Mail Gateways, but not from Cisco Secure Email Threat Defense. It would be beneficial to improve this feature. Cisco Secure Email Threat Defense can take actions, such as requesting O365 to quarantine mail. In that case, the customer requires notification to the recipient from Cisco Secure Email Threat Defense. This option would be valuable if available. The real-time threat intelligence of Cisco Secure Email Threat Defense is an AI-based classification. It took one to two months to optimize the classification, but we still experience some false positives. Reducing the learning period would be beneficial. The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned. Reducing the learning time would be much better. Additional features desired in the next release include IP restrictions and user logging IP restrictions, ensuring only the customer environment can log in to Cisco Secure Email Threat Defense. Logs forwarding needs improvement as currently it only has audit logs. In Cloud Mail Gateway, we can create an IPsec tunnel to forward logs. However, in Cisco Secure Email Threat Defense, there is no option, and we must do API integration to send logs. Only SIM can get logs; Syslog cannot retrieve them.
Jorge Abalo - PeerSpot reviewer
Endpoint Security Analyst at BNP Paribas
Endpoint protection has strengthened network control and has simplified global threat response
In my opinion, the best features Trellix Collaboration Security offers include the firewall, the on-access scan, and the ability to obtain daily signatures for the latest malware. These daily signatures, referred to as content, ensure that we are protected against the most recent malware threats recognized by other companies. Another feature I particularly enjoy is the capability to maintain different locations that can communicate with the fabric, or DXL fabric as I refer to it, allowing me to create something akin to an EDR for immediate responses to resolve issues. The DXL fabric has helped my organization by enabling communication between different locations, such as one in Europe, another in South America, and one here. This fabric communicates with a broker that interacts with the TIE servers, which maintain the reputation of files, certificates, and known signatures from various regions including Europe, South America, and Canada. When something suspicious occurs, such as a certificate appearing malicious on an application, I can easily click and indicate that I trust this file, and through the fabric, I can apply an exclusion for that application across all locations simultaneously. Other features I find valuable include the SSO integration with Trellix EPO, specifically SAML SSO, allowing people not to have to manage usernames and passwords if they already utilize an SSO service for SAML; I consider this functionality to be quite beneficial.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Currently, the ease of deployment is the low-hanging fruit for Cisco email security."
"It's very easy to deploy and configure."
"I highly recommend it as one of the best choices."
"The solution is stable."
"Cisco's technical support is very good."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The advanced threat analytics and URL filtering in threat detection are good features that are working well."
"It has an efficient email filtering feature."
"What I find most valuable with the solution is that it can integrate with cloud solutions, such as Google and Microsoft. Additionally, the solution is easy to use."
"I rely on Trellix Collaboration Security because the sensors are highly reliable and high-performance sensors that can handle traffic efficiently."
"Many similar solutions don't normally protect clients from malware, but FireEye does a very good job of protecting systems."
"I'd recommend the product due to the fact that it can stop most of the phishing and malicious items from getting through our email."
"The auto-remediation feature is valuable."
"It is one of the greatest solutions to have or to complement any other security solution such as Proofpoint or IronPort."
"The initial setup is simple."
"The product protects my email."
 

Cons

"The search area has room for improvement."
"The pricing could always be better."
"This solution could be improved by integration with Sandbox."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"The solution is a bit expensive. It could be cheaper."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"I observe that the return on investment is hindered by the lack of adequate training opportunities, with Trellix's own training being quite costly, ranging from 2,000 to 4,000 dollars, which many small or medium-sized businesses cannot afford."
"Sometimes, integration can be challenging, impacting its stability, which is why I rate it a five out of ten."
"In general, our company should make the tool more robust to protect our systems."
"The spam detection feature could be better."
"The solution needs better support."
"If you really need something powerful to handle multiple routes and delivery points then this solution might not be for you."
"There is a need for improved integration with totally different products, such as a rapid server."
"I would like the solution to be able to automatically quarantine the malicious emails before getting to the user's mailbox and continue with regular email operations. This could result in the user clicking the email before the purge operation is completed."
 

Pricing and Cost Advice

"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"The cost is very high."
"The licensing is on a yearly basis."
"The solution requires a license to be purchased for every user."
"I rate the product price as nine out of ten, where ten is the most expensive, and one is the cheapest. There is no need to pay any extra charges apart from the licensing costs."
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909,725 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Construction Company
8%
Comms Service Provider
7%
Manufacturing Company
7%
Construction Company
15%
Healthcare Company
13%
Comms Service Provider
9%
Manufacturing Company
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business15
Midsize Enterprise7
Large Enterprise17
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with FireEye Email Security?
I believe no improvements are needed for Trellix Collaboration Security as we are already using more tools from Trellix. I don't think any improvements are necessary or there are features missing i...
What is your primary use case for FireEye Email Security?
My main use case for Trellix Collaboration Security is to protect our platforms like Slack, Microsoft Teams, Google Workspace, Drive, OneDrive, and Google Drive. With the help of Trellix Collaborat...
What advice do you have for others considering FireEye Email Security?
My advice for others looking into using Trellix Collaboration Security is to prevent insider threat vectors because a colleague may unknowingly share infected files. You need to be vigilant and ens...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
FireEye Email Security
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trellix Collaboration Security and other solutions. Updated: August 2026.
909,725 professionals have used our research since 2012.