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Cisco Secure Email Threat Defense vs Trellix Collaboration Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
15
Ranking in other categories
No ranking in other categories
Trellix Collaboration Security
Ranking in Email Security
19th
Average Rating
8.6
Reviews Sentiment
7.0
Number of Reviews
15
Ranking in other categories
Instant Communications Security and Compliance (6th), Secure Email Gateway (SEG) (9th)
 

Mindshare comparison

As of August 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Trellix Collaboration Security is 2.0%, down from 2.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
BernardLugalia - PeerSpot reviewer
Provides strong data protection with virtual patching and vulnerability assessments
I primarily use it to monitor database access, particularly in banking and similar environments. It ensures that IT personnel and others do not create unauthorized accounts or users. Collaboration security assists in tracking database access and alerts in case of suspicious activity One of the…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"This solution is easy to use."
"It has an efficient email filtering feature."
"The solution is stable."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"It's very easy to deploy and configure."
"Trellix Collaboration Security is valued for being a stable and comprehensive solution that fulfills customer needs."
"The product helps reduce the number of malicious emails reaching the user's inbox."
"FireEye is good for malware depicting and security."
"We have had very good results from the use of FireEye Email Security. We are very comfortable with this technology, but I don't know if it's necessary to move into the cloud, we will check other technologies and study them. Additionally, the solution has good integration."
"Before installing, consider potential challenges with system performance, especially when integrating multiple tools, which could slow down performance."
"The initial setup is simple."
"What I find most valuable with the solution is that it can integrate with cloud solutions, such as Google and Microsoft. Additionally, the solution is easy to use."
"One of the valuable features of the product stems from the fact that it is easy to implement the tool in our environment."
 

Cons

"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"This solution could be improved by integration with Sandbox."
"The physical appliance has been discontinued, although the platform still exists."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The pricing could always be better."
"We encounter issues while searching for missing emails."
"The solution is a bit expensive."
"The solution needs better support."
"In general, our company should make the tool more robust to protect our systems."
"The solution is not easy to set up. However, we have employees that have the knowledge that can do the difficult implementation. It would be better if the process was easier."
"The reporting aspect of the solution needs improvement."
"The custom tailoring is limited."
"FireEye needs single sign-on. They say it's on their roadmap. They should also implement support for Microsoft Authenticator app for 2FA."
"I would rate them as a 1.5. The new hub created in India is not good."
"I would like to see this solution become more flexible."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The licensing is on a yearly basis."
"The cost is very high."
"The solution requires a license to be purchased for every user."
"I rate the product price as nine out of ten, where ten is the most expensive, and one is the cheapest. There is no need to pay any extra charges apart from the licensing costs."
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Top Industries

By visitors reading reviews
Computer Software Company
23%
Healthcare Company
8%
Government
6%
Manufacturing Company
6%
Manufacturing Company
18%
Computer Software Company
12%
Comms Service Provider
9%
Government
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
The pricing for Cisco Secure Email Threat Defense is relatively high. For an organization that already has the legacy system, it makes sense to continue hosting it. However, new organizations might...
What needs improvement with Secure Email Threat Defense?
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilitie...
What is your primary use case for Secure Email Threat Defense?
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering,...
What do you like most about FireEye Email Security?
One of the valuable features of the product stems from the fact that it is easy to implement the tool in our environment.
What needs improvement with FireEye Email Security?
I would like to see the addition of email digital protection features, such as anti-spam and antivirus, not just sandboxing, in the on-premises solution.
What is your primary use case for FireEye Email Security?
I have worked on Email Security ( /categories/email-security ) both on-premises and in the cloud, Web Security, and also on MDR, which is called HX endpoint security for Trellix Collaboration Secur...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
FireEye Email Security
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trellix Collaboration Security and other solutions. Updated: July 2025.
865,384 professionals have used our research since 2012.