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Cisco Secure Email Threat Defense vs Trellix Collaboration Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Trellix Collaboration Security
Ranking in Email Security
11th
Average Rating
8.8
Reviews Sentiment
6.9
Number of Reviews
19
Ranking in other categories
Instant Communications Security and Compliance (2nd), Secure Email Gateway (SEG) (6th), AI Security (9th)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Trellix Collaboration Security is 2.0%, down from 2.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Trellix Collaboration Security2.0%
Cisco Secure Email Threat Defense1.1%
Other96.9%
Email Security
 

Featured Reviews

reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
Felipe Antoniazzi - PeerSpot reviewer
Cybersecurity Engineer Lead at Johnson & Johnson
Real-time threat response has boosted detection accuracy and reduces manual investigation work
I have had challenges in the past with Trellix Collaboration Security for implementation because of issues related to compatibility. Since we worked in a global company with different operating systems, it was necessary to create different plans and different actions to implement the product.One thing I really do not prefer in Trellix Collaboration Security is not related to the console. I am a McAfee fan since the McAfee tool, and I find the console of Trellix Collaboration Security to be very user-friendly and easy to use. However, I do not know if it is related to the architecture of the product. Of course, we have modern threats based on behaviors and zero days. We have today CrowdStrike and SentinelOne, where we have better results based on threats and behavior, where it is possible to create a simulation environment based on the file detected and based on it, confirm if it really is malicious or not. In general, I believe Trellix Collaboration Security improved the console based on the last console of McAfee, but I think it is possible to improve more. It really is a good product, but in my view, it needs to improve detection based on behaviors. Regarding automations, I have implemented Trellix Collaboration Security here at Johnson & Johnson, and I implemented it in the same situation at Santander Bank and BNP Paribas Bank, where I created automations to export data for different metrics, including malicious detections, compliance, baselines, scans, last scans based on the seven days, and checking of patterns. I export everything to CSV files. Based on that, I create Power BI dashboards, and in these Power BI dashboards, I have a more executive view for different metrics to provide to myself, my manager, or director to create an executive view based on it. Another important point we use here at Johnson & Johnson and other companies is a data hub or a SIEM solution, such as Elastic or ArcSight, where we select some logs to be sent and use it to build reports and metrics.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"The solution is stable."
"The product offers protection, email security, anti-spam, and antivirus."
"This solution is easy to use."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"It has an efficient email filtering feature."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"Trellix Collaboration Security is valued for being a stable and comprehensive solution that fulfills customer needs."
"We can control this solution from the cloud and are able to access it from wherever we are."
"FireEye Email Security helps us prevent spam and phishing emails and all other business-compromised email attacks."
"The product protects my email."
"FireEye is good for malware depicting and security."
"The solution's most valuable feature is its simplicity. It's very user-friendly."
"I rely on Trellix Collaboration Security because the sensors are highly reliable and high-performance sensors that can handle traffic efficiently."
"FireEye Email Security is easy to use."
 

Cons

"The physical appliance has been discontinued, although the platform still exists."
"We encounter issues while searching for missing emails."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"This solution could be improved by integration with Sandbox."
"Sometimes, integration can be challenging, impacting its stability, which is why I rate it a five out of ten."
"It really is a good product, but in my view, it needs to improve detection based on behaviors."
"The solution is not easy to set up. However, we have employees that have the knowledge that can do the difficult implementation. It would be better if the process was easier."
"The solution must provide features to scan QR codes for threats."
"Sometimes especially zero-day spam emails can be passed to the user's inbox."
"The reporting aspect of the solution needs improvement."
"In general, our company should make the tool more robust to protect our systems."
"I chose a nine out of ten because some improvements are required, especially concerning East-West traffic or zero-day vulnerabilities."
 

Pricing and Cost Advice

"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"The solution requires a license to be purchased for every user."
"The cost is very high."
"I rate the product price as nine out of ten, where ten is the most expensive, and one is the cheapest. There is no need to pay any extra charges apart from the licensing costs."
"The licensing is on a yearly basis."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Marketing Services Firm
8%
Manufacturing Company
8%
Healthcare Company
7%
Manufacturing Company
17%
Healthcare Company
13%
Comms Service Provider
12%
Computer Software Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business8
Midsize Enterprise4
Large Enterprise10
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What do you like most about FireEye Email Security?
One of the valuable features of the product stems from the fact that it is easy to implement the tool in our environment.
What needs improvement with FireEye Email Security?
I have had challenges in the past with Trellix Collaboration Security for implementation because of issues related to compatibility. Since we worked in a global company with different operating sys...
What is your primary use case for FireEye Email Security?
In my field, I have been in the information security area for 17 years, and I am currently working in my position for a year and a half.I have worked with Trellix Collaboration Security for several...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
FireEye Email Security
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trellix Collaboration Security and other solutions. Updated: December 2025.
881,114 professionals have used our research since 2012.