Microsoft Defender for Office 365 vs Mimecast Email Security with Targeted Threat Protection comparison

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Comparison Buyer's Guide
Executive Summary
Updated on Aug 2, 2022

We performed a comparison between Microsoft Defender for Office 365 vs Mimecast Email Security with Targeted Threat Protection based on our users’ reviews in five categories. After reading all of the collected data, you can find our conclusion below.

  • Ease of Deployment: The majority of users of both solutions say the deployment is straightforward.
  • Features: Users of both solutions are happy with the products’ stability and scalability.

    Microsoft users like the solution’s ease of use, its anti-phishing feature, and its anti-malware features. Users say the product's security could be improved and that they would like to see more options to integrate it across multiple operating systems.

    Mimecast users like that the solution is user-friendly, has a great gateway, and has good sandboxing, security, and reporting. Users say its filtering features need more flexibility, that the solution could improve its detection rates, and that the user interface of the management console could be upgraded.
  • Pricing: Microsoft Defender for Office 365 users consider the pricing to be reasonable. Mimecast users say the solution is expensive.
  • Service and Support: Users of both solutions are satisfied with the technical support they receive.
  • ROI: Users of both solutions report an ROI.

Comparison Results: When all the parameters are compared, Microsoft Defender for Office 365 seems to be the more favorable choice because it is priced reasonably whereas users say Mimecast Email Security with Targeted Threat Protection is expensive.

653,757 professionals have used our research since 2012.
Featured Review
Quotes From Members
We asked business professionals to review the solutions they use.
Here are some excerpts of what they said:
Pros
"Anti-Spam and Advanced Malware Protection are the most valuable features... and we also have the option to block Zero-day attacks.""Cisco Secure Email Cloud Gateway has allowed our users to be able to concentrate on the emails that they do receive. Previously, our users had to deal with nine million additional emails across the organization, which is nearly 1,000 emails per user to have to deal with a month. That's a massive amount for our staff to deal with and probably several hours of their time. We have a lot of clinical staff, being a hospital. We want to make our staff as productive as possible. By removing a lot of that spam and phishing type emails, this allows them to do their job.""I love the Advanced Malware Protection feature. It works very well... The appliance has more security such as SDF, DKIM, DMARC, and encryption.""It is doing its work. It is doing what it was actually designed to do. It has ensured we don't have business email compromises, and it has also ensured that our brand Galaxy is unique all year round.""The solution is very configurable. It has enabled us to configure some specific filters to stop emails that general configurations didn't stop. It's a powerful solution. It can analyze a lot of emails simultaneously, with no problems of capacity or system load.""There is a huge return compared to if we didn't have a gateway appliance, as far as blocking malicious emails.""The filtering is definitely better at catching both spam and malicious messages, and there's a lot of extremely granular ability for setting up rules. You can do it the way you want to. The Microsoft solution tends to be pretty limited in how it allows some of that to be done.""The malicious URL scanning, as well as the anti-malware features, have been really useful for us in our environment."

More Cisco Secure Email Pros →

"The basic features are okay and I'm satisfied with the Defender.""Does a thorough job of examining email and URLs for malicious content.""The most valuable feature of Microsoft Defender for Office 365 is the ease of use.""Threat Explorer is one of the features that I very much like because it is a real-time report that allows you to identify, analyze, and trace security attacks.""It also gives the vulnerability status according to the versions you have selected. Let's say you have Google Chrome. It mentions the versions it has, and it updates. Within two hours of an update, it is reflected in the dashboard. That's really nice to have.""The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance.""The risk level notifications are most valuable. We get to know what kind of intrusion or attack is there, and we can fix a problem on time.""Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."

More Microsoft Defender for Office 365 Pros →

"Mimecast certainly helped my customers reduce phishing emails.""The piece that is most valuable from the Mimecast standpoint will be the sandboxing feature.""It's really quite user-friendly. In terms of technical superiority and the product itself, there are no complaints. It is really cutting edge.""The initial setup is very straightforward.""The product is good. To date, we have not faced any challenges.""In the current environment that the world is in, everyone is trying to hack everyone else, so Project+ definitely helps a lot there.""It's good, it keeps the spam out.""What I like about the integration is that it is directly into Microsoft 365, users can use their Microsoft 365 credentials to log into the portal and access their mail."

More Mimecast Email Security with Targeted Threat Protection Pros →

Cons
"The configuration UI should be made more intuitive. Currently, it takes a while to understand how to do the basic configurations.""They can do it better with web links, with the URLs. They have a technology called Outbreak but it doesn't work as well as we would like.""We have Microsoft and we have the E5 licenses, they have more EDR responses on certain emails. That's something that Cisco ESA on the cloud doesn't have. They don't do anything about MITRE attacks. They only detect if there is a malicious email or a threat and they remove it.""We have been struggling in the last month with Cisco encryption and with the S/MIME encryption. I don't know if it is an issue on our side or if these features of the solution are not working very well.""The Forged Email Detection feature needs improvement, particularly with domain. The sensors are not that good and the rules sets are unclear.""The interface is dated. It has looked pretty much the same for 15 years or so. It would be helpful to be able to do everything from one spot. The centralized quarantine and reporting are completely separate from policy administration.""The UI is definitely one area of improvement because it doesn't match other interfaces and the navigation can be a little clunky.""I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."

More Cisco Secure Email Cons →

"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement.""We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email.""Too many false positives and lacks an accurate capability to detect malicious SharePoint sites.""The company should focus on adding threats that the solution is currently unable to detect.""They can improve their security in a way where a customer can know if all their attachments are safe or not to open through a report. The solution does its job perfectly, but it never reports to the customer whether those attachments have been stopped before or not.""In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help.""It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers.""I'd like some additional features any product can give me to protect our environment in a better way."

More Microsoft Defender for Office 365 Cons →

"Their support should be improved. They are notorious for sending you to knowledge-based articles rather than actually talking to you, but that is, unfortunately, kind of becoming a trend with everything. In terms of features, I haven't had any complaints. However, I don't like the fact they moved to a paid training subscription model. They used to have a lot of free webinars for training, but they have started to charge for them in the past year.""The reaction time between a new threat being identified and Mimecast picking it up needs to be narrowed a bit.""From an administrative point of view, Mimecast is a little bit cumbersome and difficult. It's not something that the end-user can easily find navigate themselves.""The price could be better, it should be reduced.""The detection rates are an area for improvement.""While it's quick and easy, the initial setup could be more user-friendly.""The installation is not so straightforward.""As a user, the user interface of the management console could be upgraded, for example."

More Mimecast Email Security with Targeted Threat Protection Cons →

Pricing and Cost Advice
  • "The licensing was all transferred."
  • "Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
  • "Cisco Secure Email and the support are priced well. It's not cheap, but there are other solutions that offer less and cost so much. For example, Microsoft is more expensive than Cisco."
  • "There are additional fees for adding features."
  • "At times, we feel the pricing is a bit too high, but then, there is also room for discounts. We enjoy a lot of discounts, and that is why we are still with them. There are no costs in addition to the standard licensing fees."
  • "In my previous organization, avoiding four instances of CryptoLocker within an estimated six month period is approximately $600,000 in lost time and effort. Our five year cost was about a million dollars, and the four outages that we had equated to 65 percent of that five year cost."
  • "It is a super big router that costs a few hundred thousand dollars."
  • More Cisco Secure Email Pricing and Cost Advice →

  • "It's a user-base subscription."
  • "From the pricing point of view, like any other product in the market, there is scope for negotiation."
  • "Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
  • "For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
  • "Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
  • "Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
  • "The solution saves money so we have seen a return on investment."
  • More Microsoft Defender for Office 365 Pricing and Cost Advice →

  • "It's an expensive solution."
  • "The licensing costs are per-user for the product that you get with them."
  • "It is a bit expensive."
  • "I'm always going to say the price needs to be lower, but it's reasonable."
  • More Mimecast Email Security with Targeted Threat Protection Pricing and Cost Advice →

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    Questions from the Community
    Top Answer:It has an intuitive, clear graphical interface where you can deploy your policies and understand the overall flow. There… more »
    Top Answer:It is a super big router that costs a few hundred thousand dollars.
    Top Answer:You can consolidate on SMA if you want to spam or threats quarantined for multiple devices. It is not advisable for a… more »
    Top Answer:Threat Explorer is one of the features that I very much like because it is a real-time report that allows you to… more »
    Top Answer:I would recommend Microsoft Defender for Office 365. If you already have a deployment method, like CCM or something… more »
    Top Answer:There is room for improvement with the UI. The company should focus on adding threats that the solution is currently… more »
    Top Answer:It does a good job for us, and its admin console is easy to use.
    Top Answer:We typically use a subscription service. If there are version upgrades. We automatically get upgraded to the latest… more »
    Top Answer:Their support should be improved. They are notorious for sending you to knowledge-based articles rather than actually… more »
    Comparisons
    Also Known As
    Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
    MS Defender for Office 365
    Learn More
    Overview

    Customers of all sizes face the same daunting challenge: email is simultaneously the most important business communication tool and the leading attack vector for security breaches. Cisco Email Security enables users to communicate securely and helps organizations combat Business Email Compromise (BEC), ransomware, advanced malware, phishing, spam, and data loss with a multilayered approach to security.

    Microsoft Defender for Office 365 protects all of Office 365 against advanced threats like business email compromise and credential phishing, and automatically investigates and remediates attacks. With Defender for O365 you get Integrated threat protection for all of Office 365 that gives you:

    - Native protection for Office 365 with built-in protection that simplifies administration, lowers total cost of ownership, and boosts productivity.

    - Unparalleled scale and effectiveness with powerful automated workflows to improve SecOps efficiency.

    - A complete solution for collaboration that protects you from attacks across the kill chain.

    To learn more about our solution, ask questions, and share feedback, join our Microsoft Security, Compliance and Identity Community.

    Mimecast’s Advanced Email Security with Targeted Threat Protection uses multiple, sophisticated, detection engines and a diverse set of threat intelligence sources to protect email from spam, malware, phishing, and targeted attacks delivered as a 100% cloud-based service.

    Offer
    Learn more about Cisco Secure Email
    Learn more about Microsoft Defender for Office 365
    Learn more about Mimecast Email Security with Targeted Threat Protection
    Sample Customers
    SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
    Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
    Azizi Developments, Affinity Credit Union, Aftercare, Al Abbar Group
    Top Industries
    REVIEWERS
    Energy/Utilities Company19%
    Retailer14%
    Manufacturing Company10%
    Financial Services Firm10%
    VISITORS READING REVIEWS
    Computer Software Company20%
    Comms Service Provider14%
    Government7%
    Financial Services Firm7%
    REVIEWERS
    Comms Service Provider27%
    Financial Services Firm18%
    Manufacturing Company18%
    Performing Arts9%
    VISITORS READING REVIEWS
    Computer Software Company19%
    Comms Service Provider10%
    Government8%
    Financial Services Firm7%
    REVIEWERS
    Transportation Company22%
    Financial Services Firm22%
    Engineering Company11%
    Museum Or Institution11%
    VISITORS READING REVIEWS
    Computer Software Company22%
    Comms Service Provider8%
    Financial Services Firm6%
    Government6%
    Company Size
    REVIEWERS
    Small Business37%
    Midsize Enterprise23%
    Large Enterprise40%
    VISITORS READING REVIEWS
    Small Business27%
    Midsize Enterprise18%
    Large Enterprise56%
    REVIEWERS
    Small Business26%
    Midsize Enterprise26%
    Large Enterprise47%
    VISITORS READING REVIEWS
    Small Business28%
    Midsize Enterprise19%
    Large Enterprise54%
    REVIEWERS
    Small Business54%
    Midsize Enterprise8%
    Large Enterprise38%
    VISITORS READING REVIEWS
    Small Business35%
    Midsize Enterprise20%
    Large Enterprise46%
    Buyer's Guide
    Microsoft Defender for Office 365 vs. Mimecast Email Security with Targeted Threat Protection
    November 2022
    Find out what your peers are saying about Microsoft Defender for Office 365 vs. Mimecast Email Security with Targeted Threat Protection and other solutions. Updated: November 2022.
    653,757 professionals have used our research since 2012.

    Microsoft Defender for Office 365 is ranked 1st in Email Security with 15 reviews while Mimecast Email Security with Targeted Threat Protection is ranked 9th in Email Security with 11 reviews. Microsoft Defender for Office 365 is rated 8.0, while Mimecast Email Security with Targeted Threat Protection is rated 8.4. The top reviewer of Microsoft Defender for Office 365 writes "Essential security capabilities, plenty of email protection, and enhanced data loss prevention". On the other hand, the top reviewer of Mimecast Email Security with Targeted Threat Protection writes "Protects your organization from all types of threats". Microsoft Defender for Office 365 is most compared with Proofpoint Email Protection, Barracuda Email Security Gateway, Fortinet FortiMail, Microsoft Exchange Online Protection and Secure Email Threat Defense, whereas Mimecast Email Security with Targeted Threat Protection is most compared with Microsoft Exchange Online Protection, Fortinet FortiMail, Proofpoint Email Protection, Avanan and Barracuda Sentinel. See our Microsoft Defender for Office 365 vs. Mimecast Email Security with Targeted Threat Protection report.

    See our list of best Email Security vendors.

    We monitor all Email Security reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.