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MetaDefender vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

MetaDefender
Ranking in Advanced Threat Protection (ATP)
12th
Average Rating
8.8
Reviews Sentiment
6.0
Number of Reviews
15
Ranking in other categories
Anti-Malware Tools (4th), Threat Intelligence Platforms (TIP) (6th), Cloud Detection and Response (CDR) (5th)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of August 2026, in the Advanced Threat Protection (ATP) category, the mindshare of MetaDefender is 1.8%, up from 0.9% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
MetaDefender1.8%
Trellix Advanced Threat Defense1.9%
Other96.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

RS
Senior Associate at a educational organization with 11-50 employees
File protection has improved and now keeps millions of daily transfers secure and compliant
In my organization, while using this tool, we found that there were a few files flagged as suspicious; however, those were not suspicious and it was a false positive, so that can be improved. False positive results were an issue, and it took time to scan files if the file size was greater than 1 GB. For larger files greater than 1 GB, it needs to be improved. In some cases, the reconstruction of the file led to a failure of code deployment and it flagged a valid file as malicious, which was not effective; however, in other types of files, it was very effective and could scan files properly. We have already covered all the main suggestions; however, it can be improved to reduce false positive results, and scanning could be faster to process more files in a day.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"My advice to others looking into using MetaDefender is that if you are looking ahead at a solution which can be implemented quickly and at a lesser cost, go ahead with it."
"MetaDefender has strengthened file security, which is crucial in banking, by reducing the risk of malware through ensuring every file is scanned before reaching users and by improving efficiency with automated file inspection that significantly cuts down time spent on manual checks and reduces malware-related incidents and operational risks."
"The percentage of accuracy is great and the integration of multi-scanning and Content Disarm and Reconstruction affects my data security operations effectively because OPSWAT blocks the file types that we are not willing to have inside the company or are not approved."
"MetaDefender is 100% stable, making it one of the best cybersecurity solutions we offer, which provides confidence in promoting and recommending it to others."
"The best feature of MetaDefender is that it can isolate USB devices from the connected network, blocks malware and unsafe files, and ensures all endpoints follow security policy, so that my organization remains safe and reduces the risk of these threats."
"The best features of MetaDefender include its ability to detect malware and vulnerabilities, which I also use at server levels, including production and testing servers, helping me identify and address vulnerabilities by applying patch updates."
"MetaDefender is flexible because, for a free product, you can enroll up to 50 devices, and I have only used about eight devices so far."
"I like the simplicity, the way it works out of the box. It's pretty easy to run and configure. The integration of the network devices with the ICAP server was easily done."
"This solution is very easy to use and requires little to no training."
"It is stable and reliable."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The product is expensive, but it is better than the rest of them in the industry."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"I recommend this solution because of its ease of use."
 

Cons

"From the last year that we integrated OPSWAT in our company, I have not seen any improvements."
"The main improvement needed is pricing because, as an enterprise solution, smaller partners do not often receive the attention they deserve."
"I would rate it an eight because its interface can be improved and it can improve their integrations as well, so there is room for improvement."
"What I would like to see improved in MetaDefender includes reducing the high cost of the license, as the pricing is very high."
"In some cases, the reconstruction of the file led to a failure of code deployment and it flagged a valid file as malicious, which was not effective."
"While MetaDefender's mail gateway already gives fewer false positives, there is still room for improvement in reducing those even further."
"I would like to see improvements in the tool's automation capabilities."
"The documentation is not well written, and I often need to talk with support."
"The support on their side is not readily available. It takes a while."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"Lacks remote capabilities not dependent on the internet."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"This product does the job, but it is not flexible enough to do new environments yet."
"This solution needs to be made "cloud ready"."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
 

Pricing and Cost Advice

"We bought a three-year license, and that was pretty expensive. We agreed that it was really worth buying. It could be cheaper, but we understand that quality comes at a price."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
report
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
10%
Educational Organization
10%
Healthcare Company
9%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business9
Midsize Enterprise2
Large Enterprise11
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

What is your experience regarding pricing and costs for MetaDefender?
My experience with pricing, setup cost, and licensing is that it is good and at par with other competitors.
What needs improvement with MetaDefender?
I would like to see improvements in the tool's automation capabilities. It would be beneficial if it could automatically create tickets and notify responsible teams about any identified vulnerabili...
What is your primary use case for MetaDefender?
The major use cases of MetaDefender in my work environment involve preventing malware updates, data breaches, and compliance violations through scanning files for malware, vulnerabilities, and sens...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

OPSWAT MetaDefender, MetaDefender Core
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about MetaDefender vs. Trellix Advanced Threat Defense and other solutions. Updated: August 2026.
909,725 professionals have used our research since 2012.