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Palo Alto Networks WildFire vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jun 3, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Palo Alto Networks WildFire
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
72
Ranking in other categories
No ranking in other categories
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
23rd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Palo Alto Networks WildFire is 7.3%, down from 11.3% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.0%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Palo Alto Networks WildFire7.3%
Trellix Advanced Threat Defense2.0%
Other90.7%
Advanced Threat Protection (ATP)
 

Featured Reviews

RK
Engineer at Taalumgroup
Achieve effective threat prevention and seamless integration with powerful technical support
Integration with third-party products is possible. For example, connecting a mail gateway with Palo Alto Networks WildFire allows them to handle prevention. Palo Alto Networks WildFire is a cloud-based sandboxing solution. The firewall is connected to WildFire, and XDR performs sandboxing from the cloud. WildFire conducts malware scanning and emulation, then informs the firewall to block threats based on the response. It also generates reports regarding malware and other issues. The sandboxing process involves sending sample files to the cloud for scanning, checking file authenticity, certificates, and detecting malicious code. WildFire performs multiple checks and informs the XDR agent about file status. This automatic process occurs within minutes or seconds. For unknown or suspicious files, immediate blocking occurs while samples are sent to WildFire for identification. I rate Palo Alto Networks WildFire a 9 out of 10.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"WildFire's application encryption is useful."
"The graphic user interface of Palo Alto is good and it's easy to configure."
"From my perspective, Palo Alto is the best solution in the market."
"The primary use case for this solution is the attention to detail, and it is also easy to manage and easy to use."
"It catches modified signatures of known viruses."
"The backup is the best feature."
"We have used different solutions in the past but switched to Palo Alto Networks WildFire due to the fast analysis."
"The most valuable features of Palo Alto Networks WildFire are the good URL and file analysis that uses artificial intelligence, it has different interfaces such as REST, SMTP protocol, and HTTPS, the security incidents and event management are very good, additionally there are many file types that are supported and there is no limit to the number of files it can handle simultaneously, and it integrates well with SIEM solutions."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"The product is expensive, but it is better than the rest of them in the industry."
"It was easy to set up initially."
"I recommend this solution because of its ease of use."
"This solution is very easy to use and requires little to no training."
"The most valuable features are the administration console and its detection and response module."
 

Cons

"The size of Palo Alto's cloud is big but it could be easier to use from a product management perspective."
"As a firewall and 360 degrees of security, there needs to be more maturity."
"The cyber security visibility and forensics features to receive more information about incidents could improve in Palo Alto Networks WildFire."
"Perhaps an anti-spam feature could be considered."
"​The VPN and decryption need improvement."
"The support is quite difficult to access promptly. I rate it as seven out of ten."
"The solution needs more third-party integration."
"We also found that several websites do not function well with the SSL Decryption feature."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"Lacks remote capabilities not dependent on the internet."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"We'd like them to be better at dealing with script threats."
"This product does the job, but it is not flexible enough to do new environments yet."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
 

Pricing and Cost Advice

"The pricing and licensing option should be categorized for various countries such as for Bangladesh."
"It's pretty expensive but with respect to value for money, it's okay."
"The solution is a bit expensive."
"Setup costs and licensing for WildFire are comparable to other enterprise solutions."
"I think they should lower the price of this solution"
"We are on an annual subscription. When we purchased the firewall, we had activated this solutions license for a minimum of one year. The price of the solution is fair."
"The licensing fees are on an annual basis, and there are no costs in addition to the standard fees."
"The price of the Palo Alto Networks WildFire license is expensive. When it came time to renew the solution the price doubled."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Comparison Review

it_user206346 - PeerSpot reviewer
Security Consultant at Webernetz.net - Network Security Consulting
Mar 11, 2015
Cisco ASA vs. Palo Alto Networks
Cisco ASA vs. Palo Alto: Management Goodies You often have comparisons of both firewalls concerning security components. Of course, a firewall must block attacks, scan for viruses, build VPNs, etc. However, in this post I am discussing the advantages and disadvantages from both vendors concerning…
 

Top Industries

By visitors reading reviews
Manufacturing Company
11%
Computer Software Company
9%
Financial Services Firm
8%
Comms Service Provider
8%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business38
Midsize Enterprise15
Large Enterprise29
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How does Cisco Firepower NGFW Firewall compare with Palo Alto Networks Wildfire?
The Cisco Firepower NGFW Firewall is a very powerful and very complex piece of anti-viral software. When one considers that fact, it is all the more impressive that the setup is a fairly straightf...
Which is better - Wildfire or FortiGate?
FortiGate has a lot going for it and I consider it to be the best, most user-friendly firewall out there. What I like the most about it is that it has an attractive web dashboard with very easy nav...
How does Cisco ASA Firewall compare with Palo Alto's WildFire?
When looking to change our ASA Firewall, we looked into Palo Alto’s WildFire. It works especially in preventing advanced malware and zero-day exploits with real-time intelligence. The sandbox featu...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

No data available
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Novamedia, Nexon Asia Pacific, Lenovo, Samsonite, IOOF, Sinogrid, SanDisk Corporation
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Palo Alto Networks WildFire vs. Trellix Advanced Threat Defense and other solutions. Updated: June 2026.
902,270 professionals have used our research since 2012.