Microsoft Defender for Office 365 is a comprehensive security solution designed to protect organizations against advanced threats in their email, collaboration, and productivity environments. It combines the power of Microsoft's threat intelligence, machine learning, and behavioral analytics to provide real-time protection against phishing, malware, ransomware, and other malicious attacks.


| Product | Market Share (%) |
|---|---|
| Microsoft Defender for Office 365 | 10.4% |
| Proofpoint Email Protection | 7.7% |
| Abnormal Security | 6.0% |
| Other | 75.9% |
| Type | Title | Date | |
|---|---|---|---|
| Category | Email Security | Dec 29, 2025 | Download |
| Product | Reviews, tips, and advice from real users | Dec 29, 2025 | Download |
| Comparison | Microsoft Defender for Office 365 vs Check Point Harmony Email & Collaboration | Dec 29, 2025 | Download |
| Comparison | Microsoft Defender for Office 365 vs Proofpoint Email Protection | Dec 29, 2025 | Download |
| Comparison | Microsoft Defender for Office 365 vs Abnormal Security | Dec 29, 2025 | Download |
| Title | Rating | Mindshare | Recommending | |
|---|---|---|---|---|
| Microsoft Intune | 4.1 | N/A | 94% | 305 interviewsAdd to research |
| Microsoft Defender for Endpoint | 4.1 | N/A | 95% | 210 interviewsAdd to research |
| Company Size | Count |
|---|---|
| Small Business | 21 |
| Midsize Enterprise | 9 |
| Large Enterprise | 28 |
| Company Size | Count |
|---|---|
| Small Business | 1988 |
| Midsize Enterprise | 1095 |
| Large Enterprise | 2595 |
With Microsoft Defender for Office 365, organizations can safeguard their email communication by detecting and blocking malicious links, attachments, and unsafe email content. It employs advanced anti-phishing capabilities to identify and prevent sophisticated phishing attacks that attempt to steal sensitive information or compromise user credentials.
This solution also offers robust protection against malware and ransomware. It leverages machine learning algorithms to analyze email attachments and URLs in real-time, identifying and blocking malicious content before it reaches users' inboxes. Additionally, it provides advanced threat-hunting capabilities, allowing security teams to proactively investigate and respond to potential threats.
Microsoft Defender for Office 365 goes beyond email protection and extends its security features to other collaboration tools like SharePoint, OneDrive, and Teams. It scans files and documents stored in these platforms, ensuring that they are free from malware and other malicious content. It also provides visibility into user activities, helping organizations detect and mitigate insider threats.
Furthermore, this solution offers rich reporting and analytics capabilities, providing organizations with insights into their security posture and threat landscape. It enables security administrators to monitor and manage security incidents, track trends, and take proactive measures to enhance their overall security posture.
Microsoft Defender for Office 365 was previously known as MS Defender for Office 365.
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
| Author info | Rating | Review Summary |
|---|---|---|
| Cloud Solutions Architect at a tech services company with 201-500 employees | 5.0 | I've used Microsoft Defender for Office 365 for five years to protect emails, documents, and users from threats; it's stable, easy to deploy, improves threat visibility, and the attack simulation and response features are especially valuable. |
| Manager at a tech services company with 10,001+ employees | 3.5 | I've used Microsoft Defender for Office 365 extensively; it's insightful and integrates well with E5 licensing, but its cloud security lags behind competitors like Wiz and Palo Alto. Support and costs vary depending on the subscription model. |
| Senior Client Director and Advisory Service Leader at Crossfuze | 4.0 | Microsoft Defender for Office 365 protects well against phishing and malware, saves time, and reduces help desk calls. It's reliable and scalable, though Security Copilot costs are high. Setup is easy, and threat intelligence supports proactive incident response. |
| Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees | 4.5 | I use Microsoft Defender for Office 365 primarily for email, device, and identity security. Its improved anti-phishing features have reduced incidents and costs. However, navigating the multiple consoles is challenging. Prior solutions like McAfee were costlier and less user-friendly. |
| Designation Chief Consultant at Avtow | 4.0 | I use Microsoft Defender for Office 365 primarily for endpoint security. It offers robust threat response, threat visibility, and cost efficiency as part of the Microsoft 365 bundle. However, I believe the DLP capabilities could be improved. |
| Inside Solutions Architect at a retailer with 1,001-5,000 employees | 4.0 | I use Microsoft Defender for Office 365 mainly for email security, value its anti-impersonation and automation features, and find it reliable and cost-effective, though I’d like to see improved AI-driven threat prediction capabilities. |
| Head of Development at a consultancy with 1,001-5,000 employees | 4.0 | I've found Microsoft Defender for Office 365 reliable and unobtrusive, offering strong background protection and easy file scanning, though it can hinder development work due to strict policies. Overall, it's effective and centrally managed for consistent security. |
| Chief Architect at a tech vendor with 1,001-5,000 employees | 4.5 | We find the DLP feature of Microsoft Defender for Office 365 valuable for protecting sensitive data, but we encounter false positives that confuse users. While security is crucial for us as a public company, quantifying ROI remains challenging. We rely on Microsoft Azure. |