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Microsoft Defender for Endpoint vs Microsoft Defender for Office 365 comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.3
Organizations achieve financial gains and efficiency by using Microsoft Defender, eliminating third-party solutions, and enhancing security management.
Sentiment score
7.2
Microsoft Defender for Office 365 enhances email protection, reduces costs, and increases productivity, offering invaluable data security.
Without detection and protection measures, organizations would face substantial payments and reputational damage, including the necessity to inform customers about data breaches, potentially leading to loss of business.
We have seen a return on investment when using Microsoft Defender for Endpoint, as it saves labor by reducing the need for staff to focus on it.
The biggest return on investment for me when using Microsoft Defender for Endpoint is the time saving.
It has also decreased our time to detection and response by about 15 to 20 percent.
Overall, cost of owning and operating our system goes down.
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
 

Customer Service

Sentiment score
6.6
Microsoft's Defender for Endpoint support is generally effective but experiences vary; premium options offer swift, knowledgeable assistance.
Sentiment score
7.0
Microsoft Defender for Office 365 offers reliable support, praised for responsiveness, despite some challenges with clarity and third-party resolutions.
The level-one support seems disconnected from subject matter experts.
I rate Microsoft support 10 out of 10.
Due to our size, we don't have access to direct technical support, but the knowledge base, Microsoft Learn, and the articles available are really good.
Over the past two years, there have been no critical problems.
we opened tickets, and they typically resolve them quickly.
Customer service and support have been fantastic.
 

Scalability Issues

Sentiment score
7.6
Microsoft Defender for Endpoint efficiently scales with diverse enterprises, integrates seamlessly with Microsoft products, supporting growth effectively.
Sentiment score
8.2
Microsoft Defender for Office 365 scales seamlessly across configurations, supporting thousands of users with effortless integration and optimal performance.
We managed to scale it out in a short amount of time, with two months of planning and three months of implementation on 10,000 computers.
Microsoft Defender for Endpoint is scalable enough to handle various devices across environments, whether they are laptops, Android devices, or operating in hybrid environments.
Compatibility is its main feature.
We have never faced scalability problems, and Microsoft manages it effectively.
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
 

Stability Issues

Sentiment score
7.9
Microsoft Defender for Endpoint is praised for stability, efficiency, and low resource impact, despite minor occasional bugs.
Sentiment score
7.7
Microsoft Defender for Office 365 is highly reliable, offering stable performance, quick issue resolution, and high user satisfaction ratings.
I haven't seen any outages with Microsoft.
I rate Defender 10 out of 10 for stability.
Defender for Endpoint is extremely stable.
The solution is stable, as we have been using it for the past two years.
I would assess the stability and reliability of Microsoft Defender for Office 365 as very stable, with barely any issues.
Overall, the stability and reliability of Microsoft Defender for Office 365 are good.
 

Room For Improvement

Microsoft Defender for Endpoint struggles with support, integration, UI, performance issues, and lacks essential features and platform support.
Microsoft Defender for Office 365 needs enhanced virus protection, compatibility, UI, integration, reporting, and cost transparency to improve user experience.
Repeated interactions are necessary due to Level One's lack of tools and knowledge, hindering efficient problem-solving and negatively impacting our experience with Microsoft support.
We use Microsoft partners to help govern the platform, and as part of an alliance, we want to gather data from each tenant and combine them for a complete view.
Providing more detailed information on how Microsoft Defender for Endpoint detects vulnerabilities.
The main area for improvement is simplifying the implementation and rollout process.
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
There is a different console for different things; I just want one consolidated console.
 

Setup Cost

Microsoft Defender for Endpoint offers cost-effective, flexible pricing options integrated with Microsoft services, including discounts for education and volume.
Enterprise users find Microsoft Defender for Office 365 pricing complex but valuable due to integration with Office 365 features.
Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs.
It costs $15 per VM for the P2 plan, which is seen as affordable for customers.
The pricing, setup, and licensing were very easy and simple.
We've likely saved 30% of costs.
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Microsoft is quite affordable with a lot of features available for any size organization.
 

Valuable Features

Microsoft Defender for Endpoint offers seamless integration, real-time protection, and automated response, ensuring robust security with minimal impact.
Microsoft Defender for Office 365 offers comprehensive security with real-time updates and automated threat response, enhancing multi-platform enterprise safety.
Defender for Endpoint's coverage across different platforms in our environment is pretty good. We have devices running Linux, Mac OS, Windows, iOS, and Android. It covers all of them.
Microsoft Defender for Endpoint provides a unified management interface allowing customers to manage their on-premises and hybrid infrastructures from a single pane.
One of the best features of Microsoft Defender for Endpoint is its database for identifying zero-day attacks or malware attacks.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
4th
Ranking in Microsoft Security Suite
6th
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
197
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd)
Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Ranking in Microsoft Security Suite
10th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Email Security (1st), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of June 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 8.9%, down from 11.2% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 8.7%, down from 14.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Sudhen Swami - PeerSpot reviewer
Easy to update with good protection and a useful cloud portal
We've mainly used it for endpoints. However, we've also used it for DLP as well. We're also in the process of implementing it for cloud and identity as well. However, it's very good for endpoints, and that's our main focus. The malware protection is good. The visibility it provides is very useful. We can combine visibility with wider security features and alerts around malware, misconfiguration, or any other kinds of threats. The cloud portal is quite good. From there, we are able to see alerts and have colleagues review issues and monitor to see if any patterns arise. It's serving us quite well overall. It allows us to look at other items, like application and browser control. It helps us prioritize threats. We have a process in place now where we can review issues and remediate them effectively. We have been able to integrate a variety of Microsoft security products together. We use Azure AD, for example, and we've begun to implement DLP, among other items. We're looking at labeling and tagging and will expand into that soon. Defender has more stringent system requirements than, for example, Check Point. So when we implemented the Check Point Endpoint agent, that solution didn't mind what version of Windows you were using. When we moved to Defender, Defender had certain system prerequisites that had to be met. So we had to make sure that we're on a minimum version of Windows when we're utilizing Office, and Office has to be a particular version as well. It has more stringent system requirements that have to be met before you can implement it. It works natively together with other Microsoft solutions. Once you get more and more of those different components across the environment, then you start to get better visibility. So, rather than having lots of different solutions, you have fewer solutions and a single vendor solution. That way, you start getting into a position where you get better visibility and integration as well. The standardization is good. It's important. It's helping me with monitoring and learning. Updates and upgrades are quite smooth and seamless. Defender helps us automate routine tasks. Quite a lot of Microsoft is straightforward for us now. Previously, we didn't have enough resources and were unable to look at the alerts. Having this in place makes things a lot more straightforward for us. We have both the technology and the people in place now, alongside the process. We do see the benefits in that, and that's why we're continuing our adoption across the estate in terms of client and server as well. It's helping us avoid looking at multiple dashboards and centralized monitoring. We're not fully there yet. We're getting there. While we haven't witnessed time saving yet, once it's fully deployed, it will. By then, we'll have standardized processes across a single solution. We have saved money, however, as we continue to reduce non-Mircosft systems. Since we won't be using various competing technologies, we can save on licensing costs. We've likely so far saved 15%. While it's hard to estimate exactly how much, the solution has helped us decrease time to detection and time to respond.
Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
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Top Industries

By visitors reading reviews
Educational Organization
18%
Computer Software Company
12%
Government
8%
Financial Services Firm
7%
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published. It's essential to enhan...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
MS Defender for Office 365
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Microsoft Defender for Office 365 and other solutions. Updated: May 2025.
857,162 professionals have used our research since 2012.