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Microsoft Defender for Endpoint vs Microsoft Defender for Office 365 comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Endpoint offers significant ROI with cost savings, seamless integration, and real-time protection against ransomware attacks.
Sentiment score
6.9
Microsoft Defender for Office 365 offers strong ROI through security enhancements, cost savings, and improved company productivity despite measurement challenges.
Without detection and protection measures, organizations would face substantial payments and reputational damage, including the necessity to inform customers about data breaches, potentially leading to loss of business.
Consultant at ACT4SERVICES
We have seen a return on investment when using Microsoft Defender for Endpoint, as it saves labor by reducing the need for staff to focus on it.
IT CONSULTANT at a tech company with 10,001+ employees
The biggest return on investment for me when using Microsoft Defender for Endpoint is the time saving.
Lead security engineer at a computer software company with 11-50 employees
It has also decreased our time to detection and response by about 15 to 20 percent.
Technology support manager at Alfred State College
Overall, cost of owning and operating our system goes down.
Designation Chief Consultant at Avtow
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
Chief Architect at a tech vendor with 1,001-5,000 employees
 

Customer Service

Sentiment score
6.4
Many users find Microsoft Defender for Endpoint reliable, but support experiences vary, with premium support offering quicker assistance.
Sentiment score
5.8
Microsoft Defender for Office 365 users rate support highly, praising its responsiveness and 24/7 availability, despite occasional documentation and communication issues.
The Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, 'Just to set expectations, my lunch break is in an hour and I am going to go away then.'
Security Analyst III at a healthcare company with 10,001+ employees
The level-one support seems disconnected from subject matter experts.
Office 365 Subject Expert at a government with 10,001+ employees
I rate Microsoft support 10 out of 10.
Team manager of it department at a financial services firm with 501-1,000 employees
Over the past two years, there have been no critical problems.
Solution Consultant at BIM Group of Companies
we opened tickets, and they typically resolve them quickly.
Chief Architect at a tech vendor with 1,001-5,000 employees
With a subscription for Microsoft Defender for Office 365, it is an eight. Without it, it is a six.
Manager at a tech services company with 10,001+ employees
 

Scalability Issues

Sentiment score
7.4
Microsoft Defender for Endpoint is scalable and integrates well with Microsoft’s ecosystem, despite needing improvements for handling massive data.
Sentiment score
7.8
Microsoft Defender for Office 365 offers scalable, efficient protection for large enterprises, ensuring seamless growth across diverse industries.
We managed to scale it out in a short amount of time, with two months of planning and three months of implementation on 10,000 computers.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint is scalable enough to handle various devices across environments, whether they are laptops, Android devices, or operating in hybrid environments.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Compatibility is its main feature.
IT CONSULTANT at a tech company with 10,001+ employees
We have never faced scalability problems, and Microsoft manages it effectively.
Solution Consultant at BIM Group of Companies
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Chief Architect at a tech vendor with 1,001-5,000 employees
Microsoft Defender for Office 365 scales with the growing needs of my company well.
Senior Client Director and Advisory Service Leader at Crossfuze
 

Stability Issues

Sentiment score
7.9
Microsoft Defender for Endpoint is praised for its reliability and stability, with minor concerns about resource intensity and performance.
Sentiment score
7.7
Microsoft Defender for Office 365 provides 99.9% uptime with minor issues, ensuring reliable performance and seamless cloud integration.
I haven't seen any outages with Microsoft.
IT Security Engineer at a financial services firm with 1,001-5,000 employees
I rate Defender 10 out of 10 for stability.
Team manager of it department at a financial services firm with 501-1,000 employees
Defender for Endpoint is extremely stable.
Systems engineers at Delta Dental of Colorado
I would rate the stability of Microsoft Defender for Office 365 as 10 over 10 because it's highly available, it works, and it does the job it is meant to do.
Cloud Solutions Architect at a tech services company with 201-500 employees
I have not experienced any downtime, crashes, or performance issues because of Defender.
Technology Associate at a financial services firm with 51-200 employees
The solution is stable, as we have been using it for the past two years.
Solution Consultant at BIM Group of Companies
 

Room For Improvement

Microsoft Defender for Endpoint faces interface complexity, slow detection, high CPU usage, integration issues, and seeks improvements in multiple areas.
Users call for enhanced virus detection, cross-platform support, and pricing transparency in Microsoft Defender for Office 365.
Repeated interactions are necessary due to Level One's lack of tools and knowledge, hindering efficient problem-solving and negatively impacting our experience with Microsoft support.
Office 365 Subject Expert at a government with 10,001+ employees
In contrast, competing products offer reduced pricing for long-term commitments, which makes it difficult for us in that environment.
Solution Consultant at BIM Group of Companies
We use Microsoft partners to help govern the platform, and as part of an alliance, we want to gather data from each tenant and combine them for a complete view.
Team manager of it department at a financial services firm with 501-1,000 employees
The main area for improvement is simplifying the implementation and rollout process.
Infrastructure and Security Lead at Vedanta
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
Solution Consultant at BIM Group of Companies
There is a different console for different things; I just want one consolidated console.
Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees
 

Setup Cost

Microsoft Defender for Endpoint offers flexible pricing, making it competitive and cost-effective compared to standalone security products.
Microsoft Defender for Office 365 pricing is seen as flexible but potentially expensive, offering value in comprehensive security features.
That has been the trend we have seen with Microsoft lately—it is just getting more and more expensive.
Assistant Director, Hybrid Infrastructure & Operations at a insurance company with 501-1,000 employees
Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs.
Team manager of it department at a financial services firm with 501-1,000 employees
It costs $15 per VM for the P2 plan, which is seen as affordable for customers.
Snr. Infrastructure Architect (Data Centre) at LogicEra
We've likely saved 30% of costs.
Designation Chief Consultant at Avtow
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Infrastructure and Security Lead at Vedanta
Microsoft is quite affordable with a lot of features available for any size organization.
Solution Consultant at BIM Group of Companies
 

Valuable Features

Microsoft Defender for Endpoint excels with seamless integration, advanced threat intelligence, AI-driven protection, and continuous cloud-based security management.
Microsoft Defender for Office 365 enhances email security with anti-phishing, anti-malware, threat intelligence, and seamless integration for efficient management.
Defender for Endpoint's coverage across different platforms in our environment is pretty good. We have devices running Linux, Mac OS, Windows, iOS, and Android. It covers all of them.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint provides a unified management interface allowing customers to manage their on-premises and hybrid infrastructures from a single pane.
Snr. Infrastructure Architect (Data Centre) at LogicEra
One of the best features of Microsoft Defender for Endpoint is its database for identifying zero-day attacks or malware attacks.
Consultant at ACT4SERVICES
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Technology support manager at Alfred State College
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
Solution Consultant at BIM Group of Companies
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
Chief Architect at a tech vendor with 1,001-5,000 employees
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
3rd
Ranking in Microsoft Security Suite
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (2nd)
Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Ranking in Microsoft Security Suite
10th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Email Security (1st), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of January 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 6.4%, down from 7.7% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 9.7%, down from 16.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3659.7%
Microsoft Defender for Endpoint6.4%
Other83.9%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
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Top Industries

By visitors reading reviews
Computer Software Company
11%
Financial Services Firm
9%
Manufacturing Company
8%
Government
8%
Computer Software Company
13%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents, protecting my documents, and protecting attachments. I also use it to conduct ...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
MS Defender for Office 365
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Microsoft Defender for Office 365 and other solutions. Updated: December 2025.
880,745 professionals have used our research since 2012.