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ThreatLocker Zero Trust Endpoint Protection Platform vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Oct 5, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
6th
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
40
Ranking in other categories
Network Access Control (NAC) (4th), Endpoint Protection Platform (EPP) (6th), Application Control (1st), ZTNA (4th), Ransomware Protection (1st)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of January 2026, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.7%, up from 1.9% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
ThreatLocker Zero Trust Endpoint Protection Platform2.7%
Trellix Advanced Threat Defense1.9%
Other95.4%
Advanced Threat Protection (ATP)
 

Featured Reviews

CL
Supervisor, Client Security at a consultancy with 11-50 employees
World-class support and highly effective for application control and elevation
Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have. Their idea portal, unlike so many other vendors we deal with, shows movement. At least four to eight features of ThreatLocker exist because I made a request in the last five years, and it became a feature of the actual product. When it comes to improvements, we moved the product as customers, and we got to move the product by making suggestions. They seem to be very reactive to it, so there is not a whole lot that they actively need to change right now. It is one of those situations where when we run into something that would be nice to have, it happens. They make it work.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"ThreatLocker stands out because they understand application whitelisting and elevation controls deeply, addressing real issues effectively."
"The most valuable feature is selective elevation, which allows elevating an individual process to admin privilege without granting admin privilege to that user, which has been by far the most useful feature outside of the overall solution itself."
"I really enjoy ringfencing and elevation features. It makes my life easier because I do not have to get on a computer to elevate a prompt to allow users to run something they run every day as an admin."
"The application management on any workstation with the solution is valuable. I find it valuable that it indicates whether the software is part of our pre-approved list, adding a nice layer of protection. It works great because people cannot just install or download any app from the web."
"With ThreatLocker, we don't have shadow IT, and it has reduced ransomware."
"The pre-built policies and the fact that I get notified when a user requests an application are significant."
"The unified alerts are useful."
"It is a comprehensive platform that allows you to do a lot of things."
"Provides good exfiltration, and is an all-in-one product."
"The most valuable features are the administration console and its detection and response module."
"I recommend this solution because of its ease of use."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is stable and reliable."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"It is very scalable."
 

Cons

"It has not reduced helpdesk tickets. It has probably increased them by blocking applications and doing its job, resulting in people raising more tickets to know why they cannot use certain things."
"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."
"ThreatLocker could offer more flexible training, like online or offline classes after hours. The fact that they even provide weekly training makes it seem silly to suggest, but some people can't do it during the day, so they want to train after work. They could also start a podcast about issues they see frequently and what requires attention. A podcast would be helpful to keep us all apprised about what's going on and/or offline training for those people who can't train during the week."
"It would be beneficial if it became more recognized in the EU to gain respect."
"The support could be quicker."
"Some reporting areas need improvement. We need to generate more reports."
"Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have."
"Adding applications to the allowlist can sometimes feel overwhelming."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"This solution needs to be made "cloud ready"."
"Lacks remote capabilities not dependent on the internet."
"We'd like them to be better at dealing with script threats."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
 

Pricing and Cost Advice

"The pricing is reasonable and normal. I do not have any problems with the cost."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
"Its price is fair. They have added some additional things to it beyond allowlisting. They are up-charging for them, but in terms of the value we get and the way it impacts us, we get a bang for our buck with ThreatLocker than a lot of our other security tools."
"I find ThreatLocker's pricing to be reasonable for the services it provides."
"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."
"The pricing is fair and there is no hard sell."
"We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This was primarily a mistake on our part due to how we initially priced it to clients."
"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Computer Software Company
25%
Retailer
8%
Manufacturing Company
8%
Financial Services Firm
7%
Government
14%
Comms Service Provider
13%
Performing Arts
11%
University
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business32
Midsize Enterprise4
Large Enterprise3
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
Going with the theme of ThreatLocker Zero Trust Endpoint Protection Platform being a one-stop shop where they have just about everything, and they have a really good product stack as is. However, t...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about ThreatLocker Zero Trust Endpoint Protection Platform vs. Trellix Advanced Threat Defense and other solutions. Updated: December 2025.
879,422 professionals have used our research since 2012.