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ThreatLocker Zero Trust Endpoint Protection Platform vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 23, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
6th
Average Rating
9.2
Reviews Sentiment
7.6
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (6th), Application Control (2nd), ZTNA (3rd), Ransomware Protection (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
6.6
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of May 2025, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.9%, up from 1.8% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.8%, up from 1.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.
HS
Easy to set up and use with a nice interface
The scalability could be better. We'd like them to be better at dealing with script threats. In sandboxing, the time to respond is slower than we would like. We'd like them to be able to process faster. For example, Fortinet, they are doing 18,000 files per hour. For Wildfire, it is elastic. It can support as many files as you get. McAfee doesn't react like that. It does not support interfaces with HTTPS.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Being able to protect and trust nothing by default, known as zero trust, is the most important feature to me."
"The biggest improvement has been knowing that something unauthorized isn't going to get installed on anyone’s machines."
"ThreatLocker Zero Trust Endpoint Protection Platform provides no-sweat security that we can easily deploy."
"We use ThreatLocker's Allowlisting to whitelist specific applications and prevent unauthorized software from running."
"ThreatLocker provides visibility into user activity and application usage, empowering organizations to define acceptable applications and web browsers."
"Blocking is done comprehensively."
"I would rate it a ten out of ten."
"ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent."
"The most valuable features are the administration console and its detection and response module."
"I recommend this solution because of its ease of use."
"Provides good exfiltration, and is an all-in-one product."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is very scalable."
"It is stable and reliable."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
 

Cons

"We also have customers who are frustrated because they cannot do what they used to do, which was run anything they wanted to."
"Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have."
"ThreatLocker University offers many good training modules, but more in-depth training for advanced platforms would be beneficial."
"The company should strive to stay ahead of all the developments happening externally. If their progress accelerates more rapidly than the ongoing changes outside, it would prove advantageous."
"I find that the learning mode is too accessible. Technicians sometimes default to it instead of manually building policy controls."
"More visibility in the built-ins would be nice."
"It has not reduced helpdesk tickets. It has probably increased them by blocking applications and doing its job, resulting in people raising more tickets to know why they cannot use certain things."
"The snapshots used in the ThreatLocker University portal are outdated snippets and have not been updated in conjunction with the portal itself."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"Lacks remote capabilities not dependent on the internet."
"We'd like them to be better at dealing with script threats."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"This solution needs to be made "cloud ready"."
 

Pricing and Cost Advice

"Others say ThreatLocker is too expensive, and I tell them they're dreaming. It's well-priced for what it does."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."
"The pricing is fair and there is no hard sell."
"The pricing works fine for me. It's very reasonably priced."
"ThreatLocker's pricing seems justifiable."
"We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This was primarily a mistake on our part due to how we initially priced it to clients."
"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Computer Software Company
36%
Retailer
8%
Financial Services Firm
5%
Manufacturing Company
5%
Financial Services Firm
18%
Government
15%
Manufacturing Company
14%
Computer Software Company
12%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client.
What is your primary use case for McAfee Advanced Threat Defense?
We use the solution for client management and security. We used the whole suite for client Firewall, antivirus, and everything provided by Trellix.
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about ThreatLocker Zero Trust Endpoint Protection Platform vs. Trellix Advanced Threat Defense and other solutions. Updated: April 2025.
850,028 professionals have used our research since 2012.