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ThreatLocker Zero Trust Endpoint Protection Platform vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jun 29, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
9.2
Reviews Sentiment
7.5
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (7th), Application Control (1st), ZTNA (3rd), Ransomware Protection (1st)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
21st
Average Rating
7.8
Reviews Sentiment
6.6
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of August 2025, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 3.0%, up from 2.0% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.
HS
Easy to set up and use with a nice interface
The scalability could be better. We'd like them to be better at dealing with script threats. In sandboxing, the time to respond is slower than we would like. We'd like them to be able to process faster. For example, Fortinet, they are doing 18,000 files per hour. For Wildfire, it is elastic. It can support as many files as you get. McAfee doesn't react like that. It does not support interfaces with HTTPS.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The customer service is amazing."
"If all of our vendors would act and support us like ThreatLocker does, we would be happy."
"Unified Audit is excellent for identifying our denies and using those to dynamically create rules, as opposed to manually observing the logs and creating them. It saves so much time."
"ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent."
"What sets ThreatLocker apart from competitors offering similar solutions is ringfencing. The ringfencing controls, along with the application elevation features, keep it out of the user's line of sight while still protecting them."
"ThreatLocker Zero Trust Endpoint Protection Platform has helped reduce the incidents of clients getting exploits or ransomware put on their devices by 110 times."
"We are seeing a return on investment, especially with our managers and customers."
"Overall, I would rate ThreatLocker Zero Trust Endpoint Protection Platform a ten out of ten."
"Provides good exfiltration, and is an all-in-one product."
"It is stable and reliable."
"It is very scalable."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"I recommend this solution because of its ease of use."
"The most valuable features are the administration console and its detection and response module."
 

Cons

"Better visualizations of what exactly is happening in our logs would be helpful. There can be more visuals on what has been elevated. Presenting this in a more refined manner would be beneficial."
"It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down."
"This is my first Zero Trust conference, and so far, it has been good. The only thing I have noticed is that sometimes they encounter technical issues. For example, in one of the demo labs, the laptop trying to connect to the projector was not working, which affected the demonstration of the victim versus attacker laptop scenarios. It would be helpful to fix these issues."
"From my point of view, logging could be improved. Logging should be easier."
"The reporting could be improved."
"If ThreatLocker can design or build something for mobile devices, that would be brilliant."
"We use other vendors for other components. I'd like one vendor to control all aspects of the business, including backup, EDR solutions, email monitoring, and control, rather than using multiple vendors."
"More visibility in the built-ins would be nice."
"We'd like them to be better at dealing with script threats."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"Lacks remote capabilities not dependent on the internet."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"This solution needs to be made "cloud ready"."
 

Pricing and Cost Advice

"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."
"The pricing works fine for me. It's very reasonably priced."
"The pricing is fair and there is no hard sell."
"I do not deal with pricing, but I assume it is cost-effective for us. We choose a solution based on functionality and affordability."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
"Considering what this product does, ThreatLocker is very well-priced, if not too nicely priced for the customer."
"The price of ThreatLocker Allowlisting is reasonable in the market, but it is not fantastic."
"ThreatLocker's pricing seems justifiable."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Computer Software Company
31%
Retailer
8%
Manufacturing Company
6%
Financial Services Firm
6%
Government
18%
Comms Service Provider
13%
Financial Services Firm
11%
Computer Software Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client.
What is your primary use case for McAfee Advanced Threat Defense?
We use the solution for client management and security. We used the whole suite for client Firewall, antivirus, and everything provided by Trellix.
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about ThreatLocker Zero Trust Endpoint Protection Platform vs. Trellix Advanced Threat Defense and other solutions. Updated: July 2025.
865,384 professionals have used our research since 2012.