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Cisco Secure Endpoint vs Cortex XDR by Palo Alto Networks comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Sep 9, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.4
Cisco Secure Endpoint enhances productivity and reduces costs by streamlining threat detection, integrating tools, and minimizing manual intervention.
Sentiment score
7.7
Cortex XDR secures data, reduces malware, lowers costs, and replaces systems, enhancing user satisfaction and operational efficiency.
They appreciate the rich telemetry data from the solution, as it provides in-depth threat identification.
 

Customer Service

Sentiment score
6.1
Cisco Secure Endpoint support is praised for responsiveness and expertise, providing quick issue resolution and valuable user guidance.
Sentiment score
6.6
Cortex XDR support is praised for responsiveness but criticized for delayed responses and knowledge gaps in certain regions.
Cisco has good technical support, especially considering these are newer solutions compared to traditional routing and switching products.
Their support is efficient and responsive whenever I raise a ticket through my portal.
Every vendor has similar support; it depends on how the case is handled and raised.
 

Scalability Issues

Sentiment score
8.4
Cisco Secure Endpoint is scalable, integrates with SecureX for efficient management, and supports diverse industries without extra resources.
Sentiment score
7.6
Cortex XDR offers scalable, efficient data handling across Linux, Mac, and Windows, praised for simplifying large enterprise management.
Cisco Secure Endpoint is definitely scalable.
 

Stability Issues

Sentiment score
6.5
Cisco Secure Endpoint is highly stable, reliable, and trusted for performance, earning high ratings from users in various enterprises.
Sentiment score
8.1
Cortex XDR is praised for its stability and reliability, with minor issues noted but generally offering seamless protection.
We have not encountered any problems.
Cortex XDR is stable, offering high quality and reliable performance.
 

Room For Improvement

Cisco Secure Endpoint requires better integration, reporting, and UI enhancements, alongside improved pricing, AI capabilities, and IoT support.
Cortex XDR struggles with integration, high memory, false positives, limited features, complex setup, and lacks enhanced support and customization.
The forensic capabilities need enhancement, especially for deep forensic data collection.
The inclusion of this feature would allow the application of DLP policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products.
Cortex XDR could improve its sales support team, including better commission structures and referral programs.
 

Setup Cost

Cisco Secure Endpoint offers competitive and flexible pricing with value-rich features, despite some complexity in licensing.
Enterprise buyers view Cortex XDR as expensive yet flexible, offering scalable licensing with varying costs based on features and users.
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdStrike, Microsoft Defender, or SentinelOne.
Cortex XDR is perceived as expensive by some customers, yet offers dynamic pricing.
Compared to competitors such as CrowdStrike and Sophos, the pricing of Cortex XDR by Palo Alto Networks is similar to CrowdStrike but more expensive than Sophos.
 

Valuable Features

Cisco Secure Endpoint provides advanced security features, cross-platform support, and ease of use with strong threat intelligence and support.
Cortex XDR excels in cybersecurity with advanced detection, ease of use, and integration, offering scalable, efficient threat management.
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet.
It incorporates AI for normal behavior detection, distinguishing unusual operations.
The product provides automation responses in case of a threat attack, severity assessments, centralized manageability, and comprehensive compliance features, resulting in reduced costs.
 

Categories and Ranking

Cisco Secure Endpoint
Ranking in Endpoint Protection Platform (EPP)
12th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Detection and Response (EDR) (15th), Cisco Security Portfolio (6th)
Cortex XDR by Palo Alto Net...
Ranking in Endpoint Protection Platform (EPP)
4th
Average Rating
8.4
Reviews Sentiment
7.4
Number of Reviews
90
Ranking in other categories
Extended Detection and Response (XDR) (7th), Ransomware Protection (1st), AI-Powered Cybersecurity Platforms (4th)
 

Mindshare comparison

As of June 2025, in the Endpoint Protection Platform (EPP) category, the mindshare of Cisco Secure Endpoint is 1.5%, down from 1.9% compared to the previous year. The mindshare of Cortex XDR by Palo Alto Networks is 3.8%, down from 5.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP)
 

Featured Reviews

Ahmed-Dawood - PeerSpot reviewer
A tool that offers good performance and technical support along with great protection to endpoint devices
The vendor from Cisco takes care of the maintenance. We need three people to take care of the tool in case of crashes. From the dashboard, we come to know about everything related to the endpoint. You can take action unless it is not the physical hardware to which something wrong has happened, especially if something wrong happens to the operating system. I would definitely recommend the solution to those planning to use it. To provide endpoint protection, I feel the product should be speedy enough to detect malicious programs and trojans. There are a lot of tools that are not acting as signature-based but as behavior-based antivirus. Cisco Secure Endpoint is required, especially if the customers don't have a sandbox. Overall, I rate the product an eight out of ten.
NiteshSharma - PeerSpot reviewer
Automated threat response and behavioral control improve security measures
I recommend adding a data loss prevention (DLP ( /categories/data-loss-prevention-dlp )) solution to Cortex XDR ( /categories/extended-detection-and-response-xdr ) by Palo Alto Networks. The inclusion of this feature would allow the application of DLP ( /categories/data-loss-prevention-dlp ) policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products. Additionally, multi-tenancy and multi-cloud features are not available and should be considered for inclusion.
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Top Industries

By visitors reading reviews
Computer Software Company
21%
Manufacturing Company
8%
Financial Services Firm
8%
Government
8%
Computer Software Company
14%
Financial Services Firm
9%
Manufacturing Company
8%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Cisco Secure Endpoint?
The product's initial setup phase was very simple.
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdStrike, Microsoft Defender, or SentinelOne.
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with third-party tools need improvement. The forensic capabilities need enhancement,...
Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. The ability to reverse damage caused by ransomware with minimal interruptions to...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions that are very scalable, secure, and user-friendly. Cortex XDR by Palo Alto offers ...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
 

Also Known As

Cisco AMP for Endpoints
Cyvera, Cortex XDR, Palo Alto Networks Traps
 

Overview

 

Sample Customers

Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
CBI Health Group, University Honda, VakifBank
Find out what your peers are saying about Cisco Secure Endpoint vs. Cortex XDR by Palo Alto Networks and other solutions. Updated: May 2025.
856,874 professionals have used our research since 2012.