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Cisco Secure Email Threat Defense vs ESET Cloud Apps Protection comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
ESET Cloud Apps Protection
Ranking in Email Security
29th
Average Rating
9.6
Reviews Sentiment
7.4
Number of Reviews
2
Ranking in other categories
Vulnerability Management (40th), Patch Management (24th)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of ESET Cloud Apps Protection is 0.4%, up from 0.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
LA
Great protection, good privacy, and helpful support
The only thing I would like is a way to open the email that is going to quarantine. Based on the level of security, they cannot open the email to check the message. Even for the administrator, you have to create a security copy to be sent, which will lock the log support. It's not easy for an admin to check and decide if the email is good or not. That is the only thing that I'm seeing could be improved. Basically, ESET doesn't have the ability to let the administrator release an email showing the message on the email. It's not possible. If you want to have an email review, you have to select an option to send a copy. In the way that they designed the system, for security, they are not letting anyone even have the admin privileges to make this happen. Privacy is at a really high level.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"I would say that 90% of the spam and phishing attack emails get blocked right off the bat."
"We use Microsoft Defender for its ability to integrate with existing business technologies, which is beneficial for protecting business areas."
"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"The technical support is good and quick to resolve issues."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"Does a thorough job of examining email and URLs for malicious content."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"The solution is stable."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"It's very easy to deploy and configure."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"This solution is easy to use."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"Secure Email Threat Defense's scalability is good."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"We are close to having 99% or 98% detection."
"The most valuable features are the precision of detection and the level of customization of the policy."
 

Cons

"Several simulation options are available within 365, and the phishing simulation could be better."
"The product must provide better malware detection."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"There is a different console for different things; I just want one consolidated console."
"The GUI is sometimes slow to fetch the device report and could be improved."
"The phishing and spam filters could use some improvement."
"The physical appliance has been discontinued, although the platform still exists."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The pricing could always be better."
"The solution is a bit expensive."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The specific domain file for Apache needs to be well-defined."
"It's not easy for an admin to check and decide if the email is good or not."
 

Pricing and Cost Advice

"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"I know that the product is incredibly expensive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"The license is expensive because the cost is based on the number of users."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The pricing is normal. Considering its popularity, it's not overpriced."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"The solution provides affordable pricing for medium sized industries."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
29%
Healthcare Company
7%
Government
6%
Manufacturing Company
6%
Computer Software Company
15%
Comms Service Provider
13%
Media Company
8%
Wholesaler/Distributor
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What do you like most about ESET Mail Security?
The most valuable features are the precision of detection and the level of customization of the policy.
What is your experience regarding pricing and costs for ESET Mail Security?
The solution provides affordable pricing for medium sized industries.
What needs improvement with ESET Mail Security?
The specific domain file for Apache needs to be well-defined.
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
ESET Mail Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. ESET Cloud Apps Protection and other solutions. Updated: June 2025.
858,469 professionals have used our research since 2012.