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Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jul 27, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco HyperFlex HX-Series [...
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
90
Ranking in other categories
No ranking in other categories
Nutanix Cloud Infrastructur...
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
199
Ranking in other categories
Software Defined Storage (SDS) (5th), HCI (4th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)
 

Featured Reviews

Nuno Mendes - PeerSpot reviewer
High performance solution that makes it easy to efficiently manage VM resources
In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).
MahendraPanchotiya - PeerSpot reviewer
Offers a unified platform, reduces downtime, and simple updates
Nutanix offers a unified platform for managing databases, virtual machines, and applications. This simplifies management by consolidating everything into a single interface. While Nutanix may have a higher upfront cost compared to other hypervisors, it can significantly reduce the resources needed for infrastructure management. With our previous hypervisor, we needed nearly ten IT personnel. Nutanix has allowed us to streamline our team to just three members. We use a combination of database technologies, including SQL databases and web servers such as IIS, BHP, and NGINX. Nutanix features helped our organization reduce downtime. I don't recall the last time we had downtime related to Nutanix because it is such a stable product. Nutanix, a reliable product, helps us streamline our processes, which in turn improves company revenue. We began to see the benefits after two years, with a 40 percent reduction in operational costs. We migrated 200 servers from AWS to Nutanix. Nutanix may not consolidate applications, but it helps us run them more efficiently on its platform. Updating is simple with one click. I would rate the updating processes 10 out of 10. Adding compute and storage on demand is not difficult. However, we need to factor in the existing and new firmware and software requirements.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It is scalable and easy to use."
"The most valuable features are scalability and the easy operation - if it works. You can configure everything from just one window."
"Cisco HyperFlex HX has improved the way our organization functions on the storage side by having one big storage space for hosting VMs. We do not have to provision other ones. That's a positive aspect of it."
"The integration between the storage and the server applications is the most valuable feature of this solution. It cuts down on the necessity to buy a secondary storage system.. It saves money in the long-run."
"The scalability of the product is quite good overall - as long as you plan correctly from the outset."
"The software defines networking, storage, and processing."
"The most valuable feature is that you can manage the whole cluster from the traffic interconnect."
"When we use it for VDI solutions, it is very easy to deploy and support."
"The configuration is easy, and it's flexible."
"It is a good solution and it is easy to work on their platform."
"Nutanix Acropolis AOS is easy to use, integrates with other hardware configurations, and is simple to manage."
"The tool is simple, stable, and easy to upgrade. It also requires few resources to manage, which simplifies our work. The solution's ease of upgrading is its valuable feature. AHV, provided by Nutanix, is excellent in performance and ease of use. It's based on an open-source product called KVM, which I also use for other services."
"We are suggesting Nutanix to the management because of scalability and time efficiency."
"Nutanix Cloud Infrastructure's most valuable features are all the cloud facilities or benefits it provides for my data center."
"The most valuable feature is the one-click to update the firmware and software."
"One of the most valuable features is how well this solution performs. It's stable, aside from some patch issues, but it's great from a virtualization and scalability perspective."
 

Cons

"We would like HyperFlex to connect the storage directly into Fabric Interconnect along with the features of the solution. We have enough ports in HyperFlex. We don't want to buy another set of switches to connect to Fabric Interconnect, complicating the solution."
"Cisco should combine its features with its prices."
"The architecture separates data, computing, memory, and storage into different parts."
"I would like to see more analytics. It could use better infographs in the HyperFlex Connect on how traffic is running in the network. If you were reaching any capacity issues on the Fabric Interconnects, it should be able to cool all of the servers and Fabric Interconnects, then possibly integrate it with, e.g., Nexus Series switches. This should all be available in a single pane of glass."
"I have been receiving a memory overflow message every day when I use the solution."
"Maybe a better version is required to gather all of the information to allow HyperFlex to bring everything online more rapidly."
"The setup was complex, especially since we usually do all the planning, sizing, and workflows before integration."
"A stretch function is really needed. Germans think that because of the high availability and the security that two data centers are better but we want edge all in one cluster. This is a needed feature, the cluster feature, and we'd also like to see a possibility for ROBO offices."
"They have offered some new features that I have not deployed so I assume that these issues might have been addressed already, but, at my time there was a networking problem."
"Pricing and varieties of options could be better."
"It would be great if it could emulate some of the features that their competitor VMware has, for example port mirroring or Netflow output at hypervisor level."
"I believe that improvements could be made in regards to the DR in addition to deduplication and integration with others platforms. They also do not offer opportunities for network virtualization so it would be nice to see that in the future."
"In the future, I would like to see multi-tenancy in Nutanix Acropolis AOS."
"Benchmark testing indicated that workloads did slightly better on our Vblock by a few percentage"
"If they can simplify the software slightly for the installation, that would make all the difference."
"They could improve the graphical user interface."
 

Pricing and Cost Advice

"The product could be cheaper."
"There is a 30 percent additional premium that all the companies are charging for Cisco HyperFlex HX-Series because of the lack of chips and bottlenecks in the market. The cost of the solution is high right now."
"They are not the cheapest on the market. But there's an old saying I like to quote: "If you know that you are getting what you pay for, it's fine if it's expensive.""
"Cisco HyperFlex HX-Series is a bit pricier compared to other brands in the market...There is a need to make additional payments towards the maintenance and support of the solution."
"If you don't look at the costs of the systems, the scalability is quite good."
"Our licensing costs are large, but it is combined between all of the Cisco products that we have."
"The price is a bit too high."
"I would like the pricing to be cheaper."
"If a customer has been using VMware, the difference in pricing is lower. However, if they are looking to use the VMware, the price can be much higher depending on the license."
"The pricing is fair for the package."
"Nutanix Cloud Infrastructure is expensive."
"The software only licensing model is priced normally, but the licensing model that comes with hardware is priced very high. You can choose to pay the license yearly, or you can pay every three years, or every five years."
"The price of the solution is high."
"The price of the solution could improve. Nutanix has recently changed its pricing model from perpetual to subscription. They have identified there are challenges with the pricing model."
"The pricing is very competitive when compared with other vendors. As long as Nutanix goes forward with the same price and same type of offering, it will definitely have a large number of customers adopting the same solution very soon."
"We have a three-year license for the use of this solution."
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Comparison Review

it_user244362 - PeerSpot reviewer
Aug 30, 2015
Nutanix vs. VMware EVO:RAIL vs. FlexPod
Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…
 

Answers from the Community

NC
Aug 2, 2022
Aug 2, 2022
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrat...
See 2 answers
Oct 17, 2021
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.
Steffen Hornung - PeerSpot reviewer
Aug 2, 2022
With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.
 

Top Industries

By visitors reading reviews
Computer Software Company
18%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
16%
Manufacturing Company
8%
Financial Services Firm
8%
Government
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise17
Large Enterprise57
By reviewers
Company SizeCount
Small Business91
Midsize Enterprise77
Large Enterprise82
 

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...
How does VxRail compare with Cisco HyperFlex HX Series?
VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...
What makes Nutanix Cloud Infrastructure (NCI) worth using?
NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...
Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?
NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...
Do you think Nutanix Cloud Infrastructure (NCI) is a secure solution?
Nutanix Cloud Infrastructure is a very secure solution and ensures this through its Flow Network Security feature. The platform establishes a foundation through a Zero Trust strategy that is compat...
 

Also Known As

No data available
Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis
 

Overview

 

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest
St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.
Find out what your peers are saying about Dell Technologies, Broadcom, Nutanix and others in HCI. Updated: October 2025.
871,688 professionals have used our research since 2012.