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Microsoft Defender for Endpoint vs Trellix Endpoint Security Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 21, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Endpoint offers significant ROI with cost savings, seamless integration, and real-time protection against ransomware attacks.
Sentiment score
8.0
Trellix Endpoint Security offers strong ROI with enhanced security, cost savings, ease of management, and effective ransomware protection.
Without detection and protection measures, organizations would face substantial payments and reputational damage, including the necessity to inform customers about data breaches, potentially leading to loss of business.
Consultant at ACT4SERVICES
We have seen a return on investment when using Microsoft Defender for Endpoint, as it saves labor by reducing the need for staff to focus on it.
IT CONSULTANT at a tech company with 10,001+ employees
The biggest return on investment for me when using Microsoft Defender for Endpoint is the time saving.
Lead security engineer at a computer software company with 11-50 employees
We have observed tremendous return on investment after implementing Trellix Endpoint Security as it is a more cost-effective solution compared to other products.
Joint Director at PAA
Clients appreciate the solution’s customization capabilities and ongoing product improvements.
Information Security Engineer at Nhq Distribution Ltd
There are two parts: one is the encryption which is standard and no AI is needed, but the data protection part could benefit from AI to detect new types of data and protect it.
VP - Cyber Security at Olam International
 

Customer Service

Sentiment score
6.4
Many users find Microsoft Defender for Endpoint reliable, but support experiences vary, with premium support offering quicker assistance.
Sentiment score
7.4
Trellix Endpoint Security Platform's customer service is praised for efficiency but varies in consistency and response time regionally.
The Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, 'Just to set expectations, my lunch break is in an hour and I am going to go away then.'
Security Analyst III at a healthcare company with 10,001+ employees
The level-one support seems disconnected from subject matter experts.
Office 365 Subject Expert at a government with 10,001+ employees
I rate Microsoft support 10 out of 10.
Team manager of it department at a financial services firm with 501-1,000 employees
The response time is a notable issue.
Technical Associate at Valuepoint Systems
I would rate their customer service nine out of ten.
Joint Director at PAA
When we implemented Trellix Endpoint Security in their network, multiple malwares were detected.
Senior Vice President IT at AS IT Consulting Pvt. Ltd.
 

Scalability Issues

Sentiment score
7.4
Microsoft Defender for Endpoint is scalable and integrates well with Microsoft’s ecosystem, despite needing improvements for handling massive data.
Sentiment score
8.2
Trellix Endpoint Security excels in scalability, adaptability, and integration, supporting large enterprises with flexible deployment and resource management.
We managed to scale it out in a short amount of time, with two months of planning and three months of implementation on 10,000 computers.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint is scalable enough to handle various devices across environments, whether they are laptops, Android devices, or operating in hybrid environments.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Compatibility is its main feature.
IT CONSULTANT at a tech company with 10,001+ employees
I would rate the scalability of the solution as a six out of ten, indicating some challenges due to downtime requirements.
Technical Associate at Valuepoint Systems
Trellix Endpoint Security is scalable.
Joint Director at PAA
 

Stability Issues

Sentiment score
7.9
Microsoft Defender for Endpoint is praised for its reliability and stability, with minor concerns about resource intensity and performance.
Sentiment score
8.1
Trellix Endpoint Security Platform is reliable and well-rated, though occasional performance issues occur during updates or specific configurations.
I haven't seen any outages with Microsoft.
IT Security Engineer at a financial services firm with 1,001-5,000 employees
I rate Defender 10 out of 10 for stability.
Team manager of it department at a financial services firm with 501-1,000 employees
Defender for Endpoint is extremely stable.
Systems engineers at Delta Dental of Colorado
I would rate its stability as nine out of ten.
Joint Director at PAA
I would rate the stability of Trellix Endpoint Security as near perfect, close to ten out of ten.
Information Security Engineer at Nhq Distribution Ltd
I think it's stable enough; earlier it had glitches, but now it's stable enough.
VP - Cyber Security at Olam International
 

Room For Improvement

Microsoft Defender for Endpoint faces interface complexity, slow detection, high CPU usage, integration issues, and seeks improvements in multiple areas.
Trellix Endpoint Security needs improvements in speed, integration, user experience, resource usage, and compatibility for better security and support.
Repeated interactions are necessary due to Level One's lack of tools and knowledge, hindering efficient problem-solving and negatively impacting our experience with Microsoft support.
Office 365 Subject Expert at a government with 10,001+ employees
In contrast, competing products offer reduced pricing for long-term commitments, which makes it difficult for us in that environment.
Solution Consultant at BIM Group of Companies
We use Microsoft partners to help govern the platform, and as part of an alliance, we want to gather data from each tenant and combine them for a complete view.
Team manager of it department at a financial services firm with 501-1,000 employees
What needs improvement in Trellix Endpoint Security is the reduction of resource consumption by the scanning feature.
Technical Associate at Valuepoint Systems
Improvements are needed in forensic analytics to detect specific vulnerabilities.
Information Security Engineer at Nhq Distribution Ltd
The product does not seem to be cloud-native.
Architect at a government with 10,001+ employees
 

Setup Cost

Microsoft Defender for Endpoint offers flexible pricing, making it competitive and cost-effective compared to standalone security products.
Trellix Endpoint Security offers mid-range, flexible pricing with rich features, though renewal costs may rise and extras incur fees.
That has been the trend we have seen with Microsoft lately—it is just getting more and more expensive.
Assistant Director, Hybrid Infrastructure & Operations at a insurance company with 501-1,000 employees
Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs.
Team manager of it department at a financial services firm with 501-1,000 employees
It costs $15 per VM for the P2 plan, which is seen as affordable for customers.
Snr. Infrastructure Architect (Data Centre) at LogicEra
The license costs are very reasonable, around 1,000 to 1,200 rupees per year.
Technical Associate at Valuepoint Systems
Trellix Endpoint Security is cost-effective and provides excellent value for money.
Joint Director at PAA
My experience with pricing, setup cost, and licensing is good; compared to other tools, Trellix Endpoint Security Platform provides lower costs.
Senior Associate at a tech vendor with 10,001+ employees
 

Valuable Features

Microsoft Defender for Endpoint excels with seamless integration, advanced threat intelligence, AI-driven protection, and continuous cloud-based security management.
Trellix Endpoint Security excels with centralized management, integration, real-time monitoring, and adaptability for comprehensive threat protection.
Defender for Endpoint's coverage across different platforms in our environment is pretty good. We have devices running Linux, Mac OS, Windows, iOS, and Android. It covers all of them.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint provides a unified management interface allowing customers to manage their on-premises and hybrid infrastructures from a single pane.
Snr. Infrastructure Architect (Data Centre) at LogicEra
One of the best features of Microsoft Defender for Endpoint is its database for identifying zero-day attacks or malware attacks.
Consultant at ACT4SERVICES
Trellix Endpoint Security is a proven, robust, and cost-effective solution that protects the organization from different types of ransomware and attacks.
Joint Director at PAA
Including options like Application Control (formerly Solidcore), integrated monitoring, change control, DLP, and advanced threat protection, the solution offers comprehensive security.
Information Security Engineer at Nhq Distribution Ltd
The detection capability of Trellix Endpoint Security is higher than traditional antivirus solutions.
Senior Vice President IT at AS IT Consulting Pvt. Ltd.
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
2nd
Ranking in Endpoint Detection and Response (EDR)
2nd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Advanced Threat Protection (ATP) (3rd), Anti-Malware Tools (1st), Microsoft Security Suite (3rd)
Trellix Endpoint Security P...
Ranking in Endpoint Protection Platform (EPP)
7th
Ranking in Endpoint Detection and Response (EDR)
10th
Average Rating
7.8
Reviews Sentiment
7.2
Number of Reviews
159
Ranking in other categories
Extended Detection and Response (XDR) (9th)
 

Mindshare comparison

As of January 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Microsoft Defender for Endpoint is 8.2%, down from 11.5% compared to the previous year. The mindshare of Trellix Endpoint Security Platform is 3.7%, down from 4.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Endpoint8.2%
Trellix Endpoint Security Platform3.7%
Other88.1%
Endpoint Protection Platform (EPP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
Abhimanyu Das - PeerSpot reviewer
Senior Associate at a tech vendor with 10,001+ employees
Threat detection is effective, and the solution provides good control over device access, but it still needs better troubleshooting options for agent-related issues.
From an improvement perspective, I am looking for a way to troubleshoot situations where the endpoint agent becomes corrupted and requires reinstallation, as there is currently no option to resolve these issues without rebooting the system. I give it a rating of seven because, in today’s scenario, the portal is complicated to navigate. The Trellix Endpoint Security Platform dashboard is somewhat difficult to understand, and it takes considerable time to familiarize oneself with the tools and policies compared to other solutions. For on-premises deployment, I would also like to highlight that the architecture is quite complex, which is an area Trellix Endpoint Security Platform should consider improving.
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Top Industries

By visitors reading reviews
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
8%
Government
8%
Manufacturing Company
13%
Government
13%
Computer Software Company
10%
Financial Services Firm
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
By reviewers
Company SizeCount
Small Business67
Midsize Enterprise36
Large Enterprise61
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
How does McAfee Endpoint Security compare with MVISION?
The flexible manageability of McAfee Endpoint Security is one of our favorite aspects of this solution. You can deploy various components as desired with McAfee Endpoint Security, whereas many othe...
How does Crowdstrike Falcon compare with FireEye Endpoint Security?
The Crowdstrike Falcon program has a simple to use user interface, making it both an easy to use as well as an effective program. Its graphical design is such that it makes an extremely useful too...
What do you like most about McAfee Endpoint Security?
It provides a robust defense against cybersecurity threats while offering user-friendly features like notifications and approval prompts.
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Endpoint Security, McAfee Endpoint Protection, Intel Security Total Protection for Endpoint, McAfee Complete Endpoint Protection, Trellix Endpoint Security (ENS)
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
inHouseIT, Seagate Technology
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Endpoint Security Platform and other solutions. Updated: December 2025.
879,422 professionals have used our research since 2012.