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Microsoft Defender for Office 365 vs Trellix Network Detection and Response comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Office 365 offers strong ROI through security enhancements, cost savings, and improved company productivity despite measurement challenges.
Sentiment score
7.6
Trellix enhances security and productivity, offering nearly 200% ROI, faster threat detection, and broad client satisfaction.
It has also decreased our time to detection and response by about 15 to 20 percent.
Technology support manager at Alfred State College
Overall, cost of owning and operating our system goes down.
Designation Chief Consultant at Avtow
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
Chief Architect at a tech vendor with 1,001-5,000 employees
 

Customer Service

Sentiment score
5.8
Microsoft Defender for Office 365 users rate support highly, praising its responsiveness and 24/7 availability, despite occasional documentation and communication issues.
Sentiment score
7.2
Trellix Network Detection and Response offers reliable 24/7 support, though some users desire quicker response times during incidents.
Over the past two years, there have been no critical problems.
Solution Consultant at BIM Group of Companies
we opened tickets, and they typically resolve them quickly.
Chief Architect at a tech vendor with 1,001-5,000 employees
With a subscription for Microsoft Defender for Office 365, it is an eight. Without it, it is a six.
Manager at a tech services company with 10,001+ employees
Technical support needs improvement as sometimes engineers are not available promptly, especially during high-severity incidents.
Information Security Engineer at Nhq Distribution Ltd
The customer support for Trellix Network Detection and Response is great.
Agente De Servicios Técnicos at a computer software company with 11-50 employees
 

Scalability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 offers scalable, efficient protection for large enterprises, ensuring seamless growth across diverse industries.
Sentiment score
7.9
Trellix Network Detection and Response offers reliable cloud scalability, supporting diverse industries with high satisfaction despite varied admin support.
We have never faced scalability problems, and Microsoft manages it effectively.
Solution Consultant at BIM Group of Companies
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Chief Architect at a tech vendor with 1,001-5,000 employees
Microsoft Defender for Office 365 scales with the growing needs of my company well.
Senior Client Director and Advisory Service Leader at Crossfuze
 

Stability Issues

Sentiment score
7.7
Microsoft Defender for Office 365 provides 99.9% uptime with minor issues, ensuring reliable performance and seamless cloud integration.
Sentiment score
7.8
Trellix Network Detection and Response is reliable, with minor issues in performance requiring maintenance and expertise for optimal use.
I would rate the stability of Microsoft Defender for Office 365 as 10 over 10 because it's highly available, it works, and it does the job it is meant to do.
Cloud Solutions Architect at a tech services company with 201-500 employees
I have not experienced any downtime, crashes, or performance issues because of Defender.
Technology Associate at a financial services firm with 51-200 employees
The solution is stable, as we have been using it for the past two years.
Solution Consultant at BIM Group of Companies
 

Room For Improvement

Users call for enhanced virus detection, cross-platform support, and pricing transparency in Microsoft Defender for Office 365.
Trellix Network Detection and Response needs improved customization, integration, reporting, threat intelligence, AI, support, and dashboard visibility.
The main area for improvement is simplifying the implementation and rollout process.
Infrastructure and Security Lead at Vedanta
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
Solution Consultant at BIM Group of Companies
There is a different console for different things; I just want one consolidated console.
Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees
There should be improvements in AI intelligence, faster decision-making, and a more responsive technical support team.
Information Security Engineer at Nhq Distribution Ltd
I would like to see in Trellix Network Detection and Response more explanation about some details of the threat.
Agente De Servicios Técnicos at a computer software company with 11-50 employees
 

Setup Cost

Microsoft Defender for Office 365 pricing is seen as flexible but potentially expensive, offering value in comprehensive security features.
Trellix Network Detection and Response is perceived as costly, but valued for effective threat detection and competitive pricing.
We've likely saved 30% of costs.
Designation Chief Consultant at Avtow
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Infrastructure and Security Lead at Vedanta
Microsoft is quite affordable with a lot of features available for any size organization.
Solution Consultant at BIM Group of Companies
 

Valuable Features

Microsoft Defender for Office 365 enhances email security with anti-phishing, anti-malware, threat intelligence, and seamless integration for efficient management.
Trellix excels in zero-day threat detection, automatic responses, and enhancing security infrastructure with user-friendly dashboards and sandboxing.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Technology support manager at Alfred State College
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
Solution Consultant at BIM Group of Companies
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
Chief Architect at a tech vendor with 1,001-5,000 employees
Trellix NDR provides an essential defense by automatically responding to network incidents that firewalls may not catch.
Information Security Engineer at Nhq Distribution Ltd
What makes Trellix Network Detection and Response stand out for me compared to other tools is the way you can detect threats. It is very easy and comfortable to use, and the detection shows clearly on the screen, which is very easy to understand.
Agente De Servicios Técnicos at a computer software company with 11-50 employees
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Email Security (1st), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Trellix Network Detection a...
Ranking in Advanced Threat Protection (ATP)
11th
Average Rating
8.4
Reviews Sentiment
7.3
Number of Reviews
40
Ranking in other categories
Network Detection and Response (NDR) (10th)
 

Mindshare comparison

As of December 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 6.8%, down from 11.7% compared to the previous year. The mindshare of Trellix Network Detection and Response is 4.7%, down from 4.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3656.8%
Trellix Network Detection and Response4.7%
Other88.5%
Advanced Threat Protection (ATP)
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
Jose Vargas - PeerSpot reviewer
Agente De Servicios Técnicos at a computer software company with 11-50 employees
Has improved threat detection workflows and supports seamless customer monitoring
The best features Trellix Network Detection and Response offers include very good threat detection, and I believe that it is one of the best XDR tools. For example, ePO and XDR components are very comfortable and similar to many other tools for this type of monitoring, and I have received very good feedback for this tool. What makes Trellix Network Detection and Response stand out for me compared to other tools is the way you can detect threats. It is very easy and comfortable to use, and the detection shows clearly on the screen, which is very easy to understand. Regarding the features, I think that the integration with other platforms is very comfortable with the customer because we can integrate it with any switch or firewall, and it is comfortable to add this tool. Trellix Network Detection and Response has positively impacted my organization as I have improved my knowledge about detection and response. I have already used some other tools such as CrowdStrike and Umbrella, but Trellix is one of the best that I have tested. I believe that for my organization, Trellix has helped a lot with detection and supported our customers effectively. Trellix Network Detection and Response is a great tool that integrates with a lot of security tools such as Palo Alto, which is a good firewall. If you have these types of tools, your organization would benefit greatly.
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Comms Service Provider
13%
Manufacturing Company
12%
Financial Services Firm
12%
Government
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
By reviewers
Company SizeCount
Small Business20
Midsize Enterprise8
Large Enterprise19
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What do you like most about FireEye Network Security?
We wanted to cross-reference that activity with the network traffic just to be sure there was no lateral movement. With Trellix, we easily confirmed that there was no lateral network involvement an...
What is your experience regarding pricing and costs for FireEye Network Security?
My experience with pricing, setup cost, and licensing for Trellix Network Detection and Response is very great.
What needs improvement with FireEye Network Security?
I would like to see in Trellix Network Detection and Response more explanation about some details of the threat, and I wish it had more actions that you can take to contain the host or move it some...
 

Also Known As

MS Defender for Office 365
FireEye Network Security, FireEye
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
FFRDC, Finansbank, Japan Advanced Institute of Science and Technology, Investis, Kelsey-Seybold Clinic, Bank of Thailand, City of Miramar, Citizens National Bank, D-Wave Systems
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Network Detection and Response and other solutions. Updated: December 2025.
879,310 professionals have used our research since 2012.