Microsoft Defender for Cloud Apps vs Prisma Access by Palo Alto Networks comparison

Microsoft and Palo Alto Networks are both solutions in the Cloud Access Security Brokers (CASB) category. Microsoft is ranked #3 with an average rating of 8.4, while Palo Alto Networks is ranked #1 with an average rating of 8.3. Microsoft holds a 10.0% mindshare in CASB, compared to Palo Alto Networks’s 17.9% mindshare. Additionally, 100% of Microsoft users are willing to recommend the solution, compared to 92% of Palo Alto Networks users who would recommend it.

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Executive SummaryUpdated on Apr 20, 2025

Microsoft Defender for Cloud Apps and Prisma Access by Palo Alto Networks compete in the cloud security category, with each offering distinct advantages. Microsoft Defender excels in integration within the Microsoft ecosystem, while Prisma Access offers advanced zero-trust architecture and comprehensive threat prevention capabilities.

Features: Microsoft Defender for Cloud Apps is known for its cloud and identity management capabilities, excelling within Microsoft environments. It offers comprehensive threat detection and security posture management. Prisma Access provides a robust zero-trust architecture, extensive threat prevention, and app traffic protection, integrating effectively with Palo Alto's solutions.

Room for Improvement: Microsoft Defender for Cloud Apps could enhance integration with non-Windows environments, improve its user experience, and offer better integration with third-party solutions. Prisma Access can improve its user interface usability, offer more flexible configurations, and enhance integration with non-Palo Alto products.

Ease of Deployment and Customer Service: Microsoft Defender stands out for its seamless integration within Microsoft ecosystems, simplifying deployment for existing users. Prisma Access may present complexities in deployment for those not using Palo Alto products. Customer service experiences vary for both, with regional differences influencing Microsoft support and response times affecting Prisma Access support.

Pricing and ROI: Both products are premium-priced, but value can justify costs based on needs. Microsoft Defender offers cost efficiencies, especially when bundled within Microsoft E5 licenses, providing significant savings within its ecosystem. Prisma Access, though expensive, gives high returns for organizations requiring rigorous cloud security. Both demonstrate ROI through enhanced security and operational efficiencies.

To learn more, read our detailed Microsoft Defender for Cloud Apps vs. Prisma Access by Palo Alto Networks Report (Updated: June 2025).

Buyer's Guide

Microsoft Defender for Cloud Apps vs. Prisma Access by Palo Alto Networks

June 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

iboss

Mindshare comparison

As of June 2025, in the Cloud Access Security Brokers (CASB) category, the mindshare of iboss is 2.0%, up from 1.3% compared to the previous year. The mindshare of Microsoft Defender for Cloud Apps is 10.0%, down from 13.0% compared to the previous year. The mindshare of Prisma Access by Palo Alto Networks is 17.9%, down from 19.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Cloud Access Security Brokers (CASB)

Featured Reviews

Matt Crockford

Head of Cybersecurity at SES Water

It's easy to roll out, and their understanding of our business made it seamless

One aspect we value about iboss is its simplicity. Their customer service is brilliant, and they are super responsive and knowledgeable. It's easy to roll out, and their understanding of our business made it seamless. We were impressed by the solution's mental health function, which can detect if someone needs help. It scans what users are browsing and flags warning signs so we can check to see if they are okay. We've had to use it a couple of times. The user interface is highly intuitive. Our IT team picked it up with minimal training. It's arranged so that it's easy to find where things are. Another advantage is the single pane of glass console, which gives you visibility into what's happening. We're not fully there yet because we haven't implemented zero trust, but we're excited about the possibilities from the demos we've seen. We launched a POC of iboss' ChatGPT Risk Protection feature two weeks ago. AI is a great tool, but you need to be careful what you put into it. My biggest fear is employees inputting sensitive corporate information or customer PII data into one of these chatbots. I was impressed by our trial of the feature. It's exactly what we wanted. Now, when a user goes to ChatGPT, there's a banner warning them not to share information, and we can block conversations containing customer data like bank details and email addresses. I don't want to stop people from using it, but we need visibility. We've only tried it on a test group of 15 people. You can configure it to look for specific keywords or integrate it with your DLP policy if you have that configured

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Jagadeesh Gunasekaran

Cyber security engineer at a tech services company with 10,001+ employees

Saves us time, has good visibility, and a single dashboard

The solution is user-friendly and provides great visibility into threats. There are easy options available for specific workflow inspections. We can also get support by going through the Microsoft documentation, which is straightforward. Microsoft Defender for Cloud Apps helps us prioritize threats across our enterprise. It covers us from a compliance perspective and protects our organization's data. Data protection is a very important aspect of any new organization, as we need to protect our data from both external attacks and insider threats. Microsoft Defender for Cloud Apps helps us monitor for abnormal activity by insiders, which is one of the most important access points for attackers today. Additionally, the different cloud apps that Defender for Cloud Apps supports provide us with much more visibility into potential threats and activities on the internet. We have integrated Microsoft Defender for Cloud Apps alerts with Sentinel. The integration is straightforward. We can find the configuration details on Microsoft's official documentation website. If we are familiar with how Microsoft products work, we will be able to follow the instructions clearly. Microsoft Defender for Cloud Apps and Sentinel work natively together to deliver coordinated detection and response across our environment. Our integrated Microsoft solutions provide comprehensive threat protection, covering most of the tactics and techniques relevant to the MITRE ATT&CK framework. Sentinel allows us to ingest data from our entire ecosystem. When implementing an SIEM solution, there are always prerequisites such as Active Directory logs, security logs, firewall logs, and DNS logs. These are important logs that need to be ingested into the environment. Sentinel has many third-party connectors available that make integrations straightforward. Microsoft provides the configuration details in the Sentinel platform. It is important to integrate all relevant log sources into the SIEM solution so that we can detect and be alerted to any type of threat factor, whether it is from an internal or external source. Integrating third-party solutions into the platform requires a separate configuration, but Microsoft provides the necessary information. However, we need to have the appropriate permissions to execute these setups. Sentinel provides a centralized dashboard that covers threat management and configuration. It gives us complete insight into what entities are accessing, as well as full details for investigation. We can see how the alerts and threats are relevant to suspicious activities, whether they are related to malicious IP addresses, suspicious ASHAs, or any other indicators of compromise. All of this relevant data can be seen in a single pane. Recently, Microsoft introduced a new investigation experience in a single pane. This means that we can now get a lot of details in a single pane, without having to go there and execute a query. There are a lot of new insights being developed in the Sentinel platform these days. It has software intelligence. They recently introduced Microsoft Defender Threat Intelligence, which covers almost all IOCs. This protects organizational assets from threats and suspicious traffic associated with IOCs. If a match is found, alerts are generated. This is a very interesting feature. Another great feature is automation and logic apps. We can create a number of operations, such as posting in a team's channel if a severe incident occurs or sending an email notification. There are many operations available, so we can automate a lot of tasks. Microsoft Defender for Cloud Apps helps us stay compliant. It has predefined mechanisms in place to prevent attacks. For example, if an external user tries to access our SharePoint folders or files, an attack will be blocked. This is why it is important to give appropriate access to guest users. Microsoft Defender for Cloud Apps has many features and benefits. It provides a number of policies that can be configured to meet the specific needs of our security team. These policies can be used to customize cloud applications so that only authorized users can access them and perform operations that benefit the organization. In terms of safety and security, Microsoft Defender for Cloud Apps is top-notch. Using the solution's automation features, we can suppress false positive alerts. We can also close alerts, lower their severity from "high" to "low" or "informational," or close them immediately with the appropriate commands. This will depend on the configuration automation rule and the perspective from which we are testing. Microsoft Defender for Cloud Apps provides a single console. We are also provided with Microsoft templates to enable workbooks instantly. Alternatively, we can build our own customized workbooks to provide better insights and improve our SOC efficiency and overall performance. Consolidating all of our security data into one dashboard has saved our security operations team a significant amount of time. From an analyst's perspective, it is now much easier to correlate events, investigate alerts, and visualize specific entities. For example, an analyst can quickly see all of the alerts associated with a particular IP address, or they can view all of the activity for a specific entity over the past 24 hours or 7 days. This level of detail and insight would not be possible if our data were siloed in multiple dashboards. The single dashboard saves our operations approximately 20 hours per week by eliminating the need to access multiple consoles and tabs. Microsoft Defender for Cloud Apps threat intelligence can help us prepare for potential threats before they happen. However, it depends on how we develop the policies for the database to block or ignore things in our environment.

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Amar-Patil

Security Engineer at a tech services company with 1,001-5,000 employees

Enables seamless policy management and supports secure remote work

Our primary use case for Prisma Access by Palo Alto Networks is to control the internet and serve as an internet proxy. Additionally, we use it for secure remote work One of the most valuable features of Prisma Access by Palo Alto Networks is the ability to manage on-premise firewalls. We can…

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Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"iboss is among the few products providing inline filtering where no application is needed on the device."

"First of all, the security policies are essential. I do not have to rely solely on Active Directory for our users."

"We chose iboss for both zero trust and proxy (SWG) because their SWG was superior."

"I would definitely recommend iboss for web filtering purposes to other organizations or individuals."

"The security aspect of the solution, particularly the malware behind it, is excellent. That's something that really helped us out. It's not just a simple proxy that just blocks the insights of potential threats that come on behind it. They do malware detection and that helps us a lot."

"Content filtering is the most useful feature of iboss."

"Valuable features: Within the filter: Controls (Web categories, applications, and Allow/Block list) and Network (local Subnets). Within the reporter: Logs (Event Log) and Reports."

"iboss is among the few products providing inline filtering where no application is needed on the device. It operates on the network side and is not device-based. This feature was one of the main reasons why we stayed with them for so long."

More iboss pros

"Shadow IT discovery is the feature I like the most."

"The most valuable feature of Microsoft Defender for Cloud Apps is to stop shadow IT."

"If your business requirements are relatively simple, it can get the job done."

"In Microsoft Defender for Cloud Apps, there is an option to enable files. Once you enable that, it will give you all the files in your organization and where they are located in the cloud... That feature is very useful for investigation purposes."

"Everything from Microsoft is integrated. You receive regular reports on them all. You can push your reports, logs, and security alerts, which are all integrated. It is crucial that these solutions work natively together to deliver coordinated detection and response across our environment."

"The ability to sanction unsanctioned apps using Secure Score benchmarking, included in Cloud, is also beneficial."

"There are a lot of features with benefits, including discovery, investigation, and putting controls around things. You can't say that you like the investigation part but not the discovery. Everything is correlated; that's how the tool works."

"The ability to prevent users from using certain applications is one of the most valuable features. It doesn't require any configuration for implementation from the client perspective. It just works right away and gives you the information you need."

More Microsoft Defender for Cloud Apps pros

"GlobalProtect has been beneficial for its cloud security capabilities, which are vital as businesses seek hybrid options and need to support remote workers while addressing latency issues."

"Being able to use the user ID or Active Directory Group is one of the great features for control and providing more flexibility without worrying about IP addresses."

"Security is absolutely spot-on, really top-notch. It's the result of all the components that come together, such as the HIP [Host Information Profile] and components like Forcepoint, providing end-user content inspection, and antivirus. It incorporates DLP features and that's fantastic because Prisma Access makes sure that all of the essential prerequisites are in place before a user can log in or can be tunneled into."

"It supports auto-scaling for mobile users. It auto-scales depending on the mobile user traffic. For example, if 1,000 people are working from home today, and tomorrow, the number increases to 2,000, it is not going to be an issue."

"It's very stable. Sometimes after installing the boxes, we leave them for one or two years. We would just touch the box in the case of the customer needing new requirements or changes to the setup."

"We're now able to go after contracts that require a Zero Trust solution and Prisma's other technology solutions."

"It protects all app traffic so that users can gain access to all apps. Unlike other solutions that only work from ports 80 and 443, which are predominantly for web traffic, Prisma Access covers all protocols and works on all traffic patterns... The most sophisticated attacks can arise from sources that are not behind 80/443."

"Palo Alto Firewall is one of the best firewalls in the world."

More Prisma Access by Palo Alto Networks pros

Cons

"Sometimes the agent stops working in iboss, and we have to reinstall the agent."

"The reporting feature needs improvement."

"For zero trust implementation, we encountered complexity issues, especially with a large infrastructure company ExxonMobil."

"The solution could be stronger on the integration side and offer more cloud applications like G Suite or Oracle."

"Their on-premise hardware's network interface is capped at one gigabit, which is sort of a problem. If you stand a filter up where all traffic flows through that, according to them, in order to go above a gigabit, you have to have multiple devices, which in today's IT seems a little bit silly. They could easily put in an SFP port into their device that could accommodate 10 gigs or at least offer a box."

"Iboss is growing so fast that it is often hard for them to keep up with the challenges."

"The area I would like to see improvement in is the ability with in the reporter to navigate directly to the content the user is traversing. It is kind of there, but it's not perfect. Quite frequently, I receive links that lead me to pages with error messages."

"I'd like to see them accelerate development on the security side, particularly around data loss prevention."

More iboss cons

"An area of Microsoft Defender for Cloud Apps that needs to be improved or enhanced is the reporting function. In the beginning, there was a good reporting function which gave us a sort of monthly overview report. But that has gone away."

"There could be more granular roles that are out of the box included in the product."

"I would like more customization of notifications. Currently, you either get everything or you get limited information. I would like to have something in between where we can customize the data that is included in notifications."

"The insights could be improved, especially in reporting. While it is possible for me to see the usage from different cloud apps, determining if critical data has been uploaded or if it is just normal transport data is difficult."

"There are some features, such as user navigation content filtering, that are disabled by default, and it probably makes sense to enable them by default."

"Defender could integrate better with multi-cloud and hybrid environments. It requires some additional configuration to ingest data from non-Azure environments and integrate it with Sentinel."

"It takes some time to scan and apply the policies when there is some sensitive information. After it applies the policies, it works, but there is a delay. This is something for which we are working with Microsoft."

"Generally, the pricing can always be improved along with the management system."

More Microsoft Defender for Cloud Apps cons

"One area for improvement is for them to stay on top of keeping their CVEs on their platform up to date."

"We've run into some challenges, having hit a lot of bugs over the past year in the deployment of GlobalProtect. We've had our fair share of issues that I haven't been happy with. We're working with the support organization to remediate them and waiting for updated releases. The response on getting the bugs fixed has not been what I would consider adequate for a product like this."

"The BGP filtering options on Prisma Access should be improved."

"Though the monitoring is fine, the solution should improve its application graphs and interface monitoring."

"When it comes to integration mechanisms, Prisma SaaS does not support reverse proxy type of integrations."

"The initial support team is not very good. Most of the time, I have found that they are one to three years experienced only. They don't have network expertise. They know about Palo Alto products but don't know how to troubleshoot the issues. We have to guide them most of the time to troubleshoot correctly since their approach is not developed."

"Its integration with non-Palo Alto products can be improved. Currently, it is easy to integrate it with other Palo Alto products such as Cortex XDR. It integrates well with other Palo Alto products. A major part of our network is based on Palo Alto products, but for those companies that use multi-vendor products in their infrastructure, Palo Alto should optimize the integration of Prisma Access with the network devices from other vendors."

"It applies commits to the firewalls slowly. There isn't an API you can use for anything. We've previously had trouble with the egress IP addresses though we expressed to engineering that those mustn't change. They changed several times without warning, causing a lot of headaches."

More Prisma Access by Palo Alto Networks cons

Pricing and Cost Advice

"The overall pricing for iboss is very competitive and transparent."

"It is probably in line with other solutions, but I do not deal with the financial side."

"We had the cost of purchasing a new appliance along with the implementation and licensing costs. However, the following year, the cost of just licensing was similar to what was paid the previous year for a new appliance along with the implementation and licensing costs."

"It is not expensive, and it is also not cheap. iboss is priced right in the sweet spot for the number of features it offers."

"It is expensive compared to one of its competitors."

"We have not priced the solution recently, but they were competitive with other vendors in the past."

"This product is not expensive."

"The cost could be improved when you need to pay for anything. For example, refreshing files takes time to load, though it may be my Internet. To improve the refresh time, Microsoft says that we need to pay for a Premium license, and I don't like paying for things that help make a solution better."

"The E5 license offers everything bundled. People are moving to Microsoft because you buy one license and it gives you everything."

"We have an educational licensing agreement. It's a customer agreement for multiple years."

"Microsoft offers bundle discounts and a pay-as-you-go option."

"Where we are right now, this is an acceptable pricing. I would like to see more transparency given to the end user. The end user given to us is via the cloud service provider. There are different programs and license models. Some include this, and some include that. It is all over the place. There can be a little more consistency or simplification in the pricing so that your parts list is not ten pages long, and you are not trying to determine, "If I have an E3, does this cover that?", or "Do I need to pay separately for the license?" Simplification would probably be better."

"It has fair pricing. You pay for what you get. As far as I know, there are no costs in addition to the standard licensing fee."

"It is a little bit expensive. When you want to have the complete package with Office 365, Defender, and everything else, it is expensive."

More Microsoft Defender for Cloud Apps pricing and cost advice

"I would advise choosing your options according to your company's needs. Just go for what you want and do not pay for anything extra in terms of licensing. You need to determine how much bandwidth is required in your company network, and according to that, you should pay for the license. The mobile user license is based on the number of users who are going to use the VPN solution. You need to determine how many mobile users you are going to have in your network, and you should pay according to that. There are no other costs in addition to licensing, but if you go for the consultant services of Palo Alto networks to deliver the solution for you, then you need to pay something extra. That is not a part of licensing."

"The licensing model for this product is complicated and changes all the time, making it very hard for the user to comprehend the configuration."

"The pricing is very friendly. It's not confusing to figure out your workload and how much you'd be paying for the solution."

"The pricing can be difficult because it came to us with another agreement, but it can be negotiated. I highly recommend people to compare this product's performance and pricing against BetterCloud, because I feel BetterCloud is better than Prisma SaaS if they're starting from scratch."

"They price their products using credit modules."

"Prisma Access by Palo Alto Networks is an expensive solution, especially when compared to other solutions like Cisco. There are no additional charges apart from the standard licensing costs attached to the solution."

"In terms of pricing, considering that it is a two or three years old solution, they should apply big discounts for the next two or three years. This approach will be better for them to capture the market."

"The licensing fees are paid on a yearly basis and for what we get, the price is good."

More Prisma Access by Palo Alto Networks pricing and cost advice

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Top Industries

By visitors reading reviews

Computer Software Company

12%

Financial Services Firm

11%

Manufacturing Company

Government

Computer Software Company

16%

Financial Services Firm

12%

Manufacturing Company

Government

Computer Software Company

14%

Manufacturing Company

13%

Financial Services Firm

12%

Government

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

Questions from the Community

What do you like most about iboss?

Content filtering is the most useful feature of iboss.

See all answers

What needs improvement with iboss?

For zero trust implementation, we encountered complexity issues, especially with a large infrastructure company Exxon...

See all answers

What is your primary use case for iboss?

Previously when I used iboss, we did the POC for iboss for ExxonMobil. Four or five people wanted to move from our ol...

See all answers

Which is the better security solution - Cisco Umbrella or Microsoft Cloud App Security?

Cisco Umbrella is an integral component of the Cisco SASE architecture. It integrates security in a single, cloud-nat...

See all answers

What do you like most about Microsoft Cloud App Security?

It does a great job of monitoring and maintaining a security baseline. For us, that is a key element. The notificatio...

See all answers

What is your experience regarding pricing and costs for Microsoft Cloud App Security?

My impression on the pricing, setup costs, and licensing of Microsoft Defender for Cloud Apps is that it's fair. I do...

See all answers

What is the better solution - Prisma Access or Zscaler Private Access?

We looked into Prisma Access before choosing Zscaler Private Access (ZPA). Palo Alto’s Prisma Access is a secure ac...

See all answers

What do you like most about Prisma Access by Palo Alto Networks?

The most valuable features of the solution are in the areas of the secure remote access it provides while also being ...

See all answers

What is your experience regarding pricing and costs for Prisma Access by Palo Alto Networks?

From my experience, Palo Alto is more expensive compared to solutions like Netskope and Triscale.

See all answers

Comparisons

Zscaler Internet Access vs iboss

Compared 18% of the time

Netskope vs iboss

Compared 15% of the time

Cisco Umbrella vs iboss

Compared 14% of the time

Cloudflare One vs iboss

Compared 8% of the time

Menlo Secure vs iboss

Compared 3% of the time

More iboss Competitors

Zscaler Internet Access vs Microsoft Defender for Cloud Apps

Compared 21% of the time

Cisco Umbrella vs Microsoft Defender for Cloud Apps

Compared 14% of the time

Netskope vs Microsoft Defender for Cloud Apps

Compared 12% of the time

Skyhigh Security vs Microsoft Defender for Cloud Apps

Compared 6% of the time

Microsoft Defender for Cloud vs Microsoft Defender for Cloud Apps

Compared 3% of the time

More Microsoft Defender for Cloud Apps Competitors

Cisco Umbrella vs Prisma Access by Palo Alto Networks

Compared 12% of the time

Netskope vs Prisma Access by Palo Alto Networks

Compared 10% of the time

Zscaler Internet Access vs Prisma Access by Palo Alto Networks

Compared 7% of the time

FortiSASE vs Prisma Access by Palo Alto Networks

Compared 7% of the time

Netskope Private Access vs Prisma Access by Palo Alto Networks

Compared 2% of the time

More Prisma Access by Palo Alto Networks Competitors

Product Reports

Buyer's Guide

iboss

June 2025

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Buyer's Guide

Microsoft Defender for Cloud Apps

May 2025

Microsoft Defender for Cloud Apps report

Download Microsoft Defender for Cloud Apps product report

Buyer's Guide

Prisma Access by Palo Alto Networks

May 2025

Prisma Access by Palo Alto Networks report

Download Prisma Access by Palo Alto Networks product report

Also Known As

iBoss Cloud Platform

MS Cloud App Security, Microsoft Cloud App Security

Palo Alto Networks Prisma Access, Prisma Access, GlobalProtect, Palo Alto GlobalProtect Mobile Security Manager, Prisma SaaS by Palo Alto Networks, Prisma Access

Overview

iboss offers a comprehensive security platform designed for diverse use cases such as web filtering, data loss protection, corporate proxy services, and URL filtering.

iboss integrates advanced features to address dynamic security needs, leveraging its strength in SASE, ZTNA, AI initiatives, and cloud integration, while ensuring seamless operations for remote work. It excels in historical forensics, malware protection, and flexible cloud deployments. Users benefit from comprehensive traffic scanning, robust malware detection, and PaaS capabilities that reduce hardware management. An intuitive admin console ensures efficient management with content filtering and low false positives. SSL decryption enhances security, while DLP protects data in AI conversations. Deployment is rapid and scalable, allowing effortless integration with emerging technologies.

What features does iboss offer?

Granular Web Filtering: Provides precise control over web content access.
Traffic Scanning: Monitors data through multiple ports for security breaches.
Malware Detection: Ensures superior protection against malware threats.
PaaS Capabilities: Eliminates need for hardware management.
SSL Decryption: Enhances data protection by decrypting secure connections.
DLP Capabilities: Safeguards data during AI interactions.

What benefits and ROI should users consider?

Scalability: Adapts quickly to growing demands and emerging tech integration.
Rapid Deployment: Reduces time to implement security measures.
User-Friendly Admin Console: Facilitates efficient operations management.
Low False Positives: Increases accuracy of threat detection systems.

iboss finds significant application in sectors such as education, where web filtering for K-12 is crucial, and in corporate environments requiring robust proxy services and URL filtering for network security. Its adaptability is essential in scenarios demanding flexible, decentralized security frameworks, particularly for remote work setups.

iboss

Microsoft Defender for Cloud Apps is a comprehensive security solution that provides protection for cloud-based applications and services. It offers real-time threat detection and response, as well as advanced analytics and reporting capabilities. With Defender for Cloud Apps, organizations can ensure the security of their cloud environments and safeguard against cyber threats. Whether you're running SaaS applications, IaaS workloads, or PaaS services, Microsoft Defender for Cloud Apps can help you secure your cloud environment and protect your business from cyber threats.

Microsoft Defender for Cloud Apps Benefits:

Provides comprehensive security for cloud applications
Integrates with other Microsoft security tools
Easy to use and deploy
Provides real-time threat detection and response
Strong protection against phishing attacks and other common threats
Highly customizable to meet specific needs of different organizations

Microsoft Defender for Cloud Apps Use Cases:

Governance, authentication, security, and compliance.
Detects shadow IT and anomalous user behavior
Controls access to applications
Provides auditing and filtering setups
Used for end-user compute devices, file monitoring, user investigation, and activity
Used for data governance, threat detection, and getting visibility over cloud applications
Used to identify information about applications beyond organizational boundaries
Prevent exfiltration and data filtration of corporate data
Used to deal with spam emails and detect shadow IT

Reviews from Real Users

Ram-Krish, Cloud Security & Governance at a financial services firm, says that Microsoft Defender for Cloud Apps "Integrates well and helps us in protecting sensitive information, but takes time to scan and apply the policies and cannot detect everything we need".

PeerSpot user, Senior Cloud & Security Consultant at a tech services, writes that Microsoft Defender for Cloud Apps "Great for monitoring user activity and protecting data while integrating well with other applications".

Simon Burgess,Infrastructure Engineer at SBITSC, states that Microsoft Defender for Cloud Apps is "A fluid, intelligent product for great visibility, centralized management, and increased uptime".

Microsoft

Prisma Access by Palo Alto Networks provides consistent security for all users and applications across your remote networks. Prisma Access grants users safe access to the cloud and data center applications and the internet as well. In addition, the solution combines all of your security and networking capabilities into a single cloud-delivered platform, enabling flexible hybrid workforces.

Prisma Access can be managed two ways:

Cloud Managed
Panorama Managed

Prisma Access delivers both networking and security services, including:

SD-WAN
VPN
Zero Trust network access (ZTNA)
Quality of service (QoS)
Clean Pipe
Firewall as a service (FWaaS)
DNS Security
Threat Prevention
Cloud secure web gateway (SWG)
Data loss prevention (DLP)
Cloud access security broker (CASB)

Prisma Access by Palo Alto Networks Features

Prisma Access by Palo Alto Networks has many valuable key features including: App-ID, User-ID, Device-ID, SSL Decryption, Dynamic User Group (DUG) Monitoring, AI/ML-Based Detection, IoT Security, Reporting, URL Filtering, Enterprise Data Loss Prevention (DLP), Digital Experience Monitoring (DEM)*, Logging, Policy Automation, Intrusion Prevention System (IPS), and many more.

Prisma Access by Palo Alto Networks Benefits

Some of the benefits of using Prisma Access by Palo Alto Networks include:

Security: Prisma Access gives you consistent security to protect against cyberattacks, with enforcement of policy at every location. By implementing Prisma Access, you also gain protection that works to prevent known and unknown malware, exploits, credential theft, command and control, and many other attack vectors across all ports and protocols.
Global connectivity: Prisma Access provides global coverage through use of its connectivity layer.
Scalability: With Prisma Access, scaling is automatically managed and is scalable, flexible, and agile.
Instant deployment: Deployment is fast, eliminating wasted time that may otherwise be associated with setting up a solution, operating it, or shipping hardware in order to get started.

Reviews from Real Users

Below are some reviews and helpful feedback written by Microsoft Azure Synapse Analytics

users who are currently using the solution.

PeerSpot user Partha D., Global Network Tech Lead at a computer software company, speaks about his experience using the product, saying, "It protects all app traffic so that users can gain access to all apps. Unlike other solutions that only work from ports 80 and 443, which are predominantly for web traffic, Prisma Access covers all protocols and works on all traffic patterns... The most sophisticated attacks can arise from sources that are not behind 80/443."

Tejas J., a Sr. Cloud Security Architect at a computer software company, mentions that "it is geographically dispersed, and it sits on top of Google and AWS platforms. Therefore, you don't face the standard issues, such as latency or bandwidth issues, that you usually face in the case of on-prem data centers.”

Another PeerSpot reviewer, Max I., Associate Director at Cognizant, comments that "Security is absolutely spot-on, really top-notch. It's the result of all the components that come together, such as the HIP [Host Information Profile] and components like Forcepoint, providing end-user content inspection, and antivirus. It incorporates DLP features and that's fantastic because Prisma Access makes sure that all of the essential prerequisites are in place before a user can log in or can be tunneled into."

Palo Alto Networks

Sample Customers

More than 4,000 global enterprises trust the iboss Cloud Platform to support their modern workforces, including a large number of Fortune 50 companies.

Customers for Microsoft Defender for Cloud Apps include Accenture, St. Luke’s University Health Network, Ansell, and Nakilat.

Concord Hospital, State of Colorado, Essilor International, RheinLand Versicherungsgruppe, University of Westminster, Universidade Nove de Julho, SPAR Austria, CAME Group, ZipRealty, Greenhill & Co., IKT Agder, Aviva Stadium, Animal Logic, Management & Training Corporation, Brigham Young University Hawaii, School District of Chilliwack

Buyer's Guide

Microsoft Defender for Cloud Apps vs. Prisma Access by Palo Alto Networks

June 2025

Free Report: Microsoft Defender for Cloud Apps vs. Prisma Access by Palo Alto Networks

Find out what your peers are saying about Microsoft Defender for Cloud Apps vs. Prisma Access by Palo Alto Networks and other solutions. Updated: June 2025.

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