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High Performance Computing (HPC) vs Nutanix Cloud Infrastructure (NCI) comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jun 3, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

High Performance Computing ...
Ranking in Hybrid Cloud Computing Platforms
13th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
2
Ranking in other categories
No ranking in other categories
Nutanix Cloud Infrastructur...
Ranking in Hybrid Cloud Computing Platforms
5th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
199
Ranking in other categories
Software Defined Storage (SDS) (4th), HCI (2nd), Software Defined Data Center (SDDC) (1st)
 

Mindshare comparison

As of October 2026, in the Hybrid Cloud Computing Platforms category, the mindshare of High Performance Computing (HPC) is 4.0%, up from 3.4% compared to the previous year. The mindshare of Nutanix Cloud Infrastructure (NCI) is 9.0%, up from 7.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Hybrid Cloud Computing Platforms Mindshare Distribution
ProductMindshare (%)
Nutanix Cloud Infrastructure (NCI)9.0%
High Performance Computing (HPC)4.0%
Other87.0%
Hybrid Cloud Computing Platforms
 

Featured Reviews

MA
Global Datacenter Infrastructure and HPC Director at a manufacturing company with 10,001+ employees
Helps to run simulations and create prototypes which reduces the costs
HPC's neutral configuration is not difficult. The tool's deployment depends on your understanding of its architecture and use cases. I rate it a three out of five. A regular cluster will take two weeks to set up. OEMs helped us with the physical hardware installation. Once the cluster was running, our team configured the software and networks.
JD
Dsi at OFFICE PUBLIC DE L HABITAT DE ROUEN
Hyper-converged storage has improved performance and now supports high redundancy for our VMs
Nutanix Cloud Infrastructure (NCI) was transparent because we were on a regular infrastructure before. We went on NCI and were able to improve performance, but it did not really change how things worked. The performance was really better for applications and access times to the data. I regularly looked at the analytics to see what was going on in my servers and what it was saying to optimize performance. It was pretty interesting because it could analyze and give insights on how to get things working better. In the latest versions, the Prism interface has been replaced by Prism Central. This requires another machine to be deployed to manage the servers.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Our customers can publish scientific reports in prestigious magazines. HPC offers strong computing capabilities."
"HPC speeds up delivery time and reduces costs. It comes with the capability and flexibility to understand how engineering products work. You can understand the outcome without spending time and money."
"This operating system offers stability. Setup is straightforward."
"The technical support for this product is very good; we launched a lot of cases with their support team and we received a lot of help from them, and they also have a support portal that contains a lot of articles that help you resolve the issues more quickly."
"With the whole rack becoming a 2U Box, we had a smaller data center footprint and power consumption, and compute and storage became one, so it became easier to manage."
"For the industry they are in, Nutanix is some amazing stuff."
"Scaling is very easy and no limitations are set."
"In the world of IT operations, there is a lot of noise. Traditionally, systems would generate a great deal of alerts, events, and notifications, often leading to the operator either a) not seeing critical alerts since they are lost in the noise or b) disregarding the alerts/events."
"It's easy to manage with the one-click hypervisor and firmware upgrade, and we can also store data more efficiently with compression and deduplication."
"The product is easy to manage."
 

Cons

"There was a buzz around the integration of quantum computing and HPC. However, I don't see a real-life use case for it."
"The solution is expensive."
"Nutanix Cloud Infrastructure lacks compatibility with certain older processors."
"It would be nice to be able to converge the network switch required to connect the Nutanix nodes together."
"The installation for Nutanix was not easy. We needed to do many interactive things in order to install it, and there were many controllers."
"It would be ideal if it was more secure."
"This was a POC and due to the high cost of the solution we did not end up deploying the technology."
"I don't feel that I am receiving the performance which I am paying for."
"The solution is about 70% stable."
"The one disadvantage is relative, financially Nutanix Acropolis AOS is a little bit more expensive than the old solution."
 

Pricing and Cost Advice

Information not available
"It is slightly more expensive compared to a standard, on-prem, bare-metal configuration. There is about a 30 percent overhead there."
"They should lower the price. If they did they would fall into a more competitive market because the price does scare a lot of potential customers away when they get the quote."
"The basic license that comes with the box allows basic virtualization features but advanced automation features would require an upgrade of licenses."
"I know Nutanix and VxRail have similar prices and licenses. Nutanix is a go-ahead if AHV is used as hypervisor because it is already embedded in the price."
"Work close with your InfraTeam and discuss with Nutanix the best way to achieve sizing and price that are right for you."
"Nutanix Acropolis AOS is affordable, it has good value. The final price depends a lot on the hardware used, it's an appliance in the end. Whether you use HPE as the hardware vendor or Supermicro as the hardware vendor, it really depends on what hardware is used which is the main cost."
"Nutanix is cheaper than Cisco HyperFlex, although it depends on the configuration because Nutanix can also be expensive."
"It is not cheap, but if you look at the return on investment and the total cost of ownership, it is worth the price."
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Comparison Review

it_user244362 - PeerSpot reviewer
Managing Consultant with 51-200 employees
Aug 30, 2015
Nutanix vs. VMware EVO:RAIL vs. FlexPod
Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…
 

Top Industries

By visitors reading reviews
Comms Service Provider
10%
Financial Services Firm
9%
Construction Company
9%
University
9%
Outsourcing Company
11%
Manufacturing Company
9%
Computer Software Company
8%
Financial Services Firm
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
By reviewers
Company SizeCount
Small Business93
Midsize Enterprise76
Large Enterprise88
 

Questions from the Community

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How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...
What makes Nutanix Cloud Infrastructure (NCI) worth using?
NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...
Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?
NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...
 

Also Known As

No data available
Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis
 

Overview

 

Sample Customers

Information Not Available
St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.
Find out what your peers are saying about High Performance Computing (HPC) vs. Nutanix Cloud Infrastructure (NCI) and other solutions. Updated: September 2026.
915,341 professionals have used our research since 2012.