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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
15
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
6th
Average Rating
8.2
Reviews Sentiment
6.8
Number of Reviews
40
Ranking in other categories
Anti-Malware Tools (9th)
 

Mindshare comparison

As of August 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 6.0%, down from 8.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Amber Worth - PeerSpot reviewer
Retrieves data from quarantines and easy to read logs with robust security features
Some of the searchability when looking for specifics in Exchange logs is tedious. Although eventually the information is located, it can be difficult if detailed information is lacking. Improving the search process by allowing searches with different types of parameters and facilitating searches within emails would be advantageous. Simplifying interfaces would also be appreciated.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The solution is stable."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"Secure Email Threat Defense's scalability is good."
"It has an efficient email filtering feature."
"This solution is easy to use."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"It is scalable."
"It provides security to both on-premises and Azure infrastructures."
"Microsoft EOP's most valuable feature is a shared mailbox."
"Microsoft Exchange Online Protection has features like DLP (data loss protection), Safe Attachment, and Safe Links."
"It's definitely scalable."
"The email policy configuration options in Microsoft EOP are satisfactory."
"The product protects against malware."
"We can migrate seamlessly without any disruptions to our operations."
 

Cons

"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The physical appliance has been discontinued, although the platform still exists."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"It would be helpful for customers if Plan 1 features were included with EOP."
"We would like the solution to have more in-built intelligence in the way that it reviews potential security risks, rather than our team constantly having to update the policies."
"Microsoft has some training portals, but more could be developed."
"It doesn't protect against everything. We do need protection for, for example, endpoints."
"The solution lacks to elaborate on its spam policies."
"The security features could be better."
"The licensing can be on the expensive side, especially in the cloud space."
"Not all settings can be configured automatically and most still require manual configuration. However, there is an automation tool available that can be used to input all the configurations either as a script or a tool it would be helpful."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"Apart from the license fee for the solution, there are no additional costs."
"The solution should reduce the cost."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
"Online Protection is fairly expensive."
"The tool's pricing is excellent."
"It's a high price."
"On a scale of one to ten, where one is cheap, and ten is very expensive, I rate the pricing a six. For licensing, we can make monthly or yearly payments. Right now, we pay 5 USD per month to secure a person's license."
"It is a low-price solution."
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Top Industries

By visitors reading reviews
Computer Software Company
24%
Healthcare Company
8%
Manufacturing Company
6%
Government
6%
Computer Software Company
14%
Financial Services Firm
9%
Government
8%
Manufacturing Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
The pricing for Cisco Secure Email Threat Defense is relatively high. For an organization that already has the legacy system, it makes sense to continue hosting it. However, new organizations might...
What needs improvement with Secure Email Threat Defense?
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilitie...
What is your primary use case for Secure Email Threat Defense?
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering,...
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
Reporting could be one of the areas for improvement, as they could put more reporting into Microsoft Exchange Online Protection (EOP) natively rather than requiring additional licensing or connecti...
What is your primary use case for Microsoft Exchange Online Protection?
The company does work with this technology, but not me personally. I manage some other products currently, mainly in the modern workplace space, such as Azure Virtual Desktop and Microsoft 365. I d...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: July 2025.
865,576 professionals have used our research since 2012.