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Microsoft Defender XDR vs ReliaQuest GreyMatter comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
113
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Endpoint Detection and Response (EDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Endpoint Detection and Response (EDR) (8th), Microsoft Security Suite (4th)
ReliaQuest GreyMatter
Ranking in Extended Detection and Response (XDR)
25th
Average Rating
9.6
Reviews Sentiment
8.1
Number of Reviews
2
Ranking in other categories
Digital Risk Protection (11th), Managed Detection and Response (MDR) (18th)
 

Mindshare comparison

As of June 2026, in the Extended Detection and Response (XDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 4.6%, down from 5.1% compared to the previous year. The mindshare of Microsoft Defender XDR is 4.2%, down from 5.9% compared to the previous year. The mindshare of ReliaQuest GreyMatter is 0.9%, up from 0.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Extended Detection and Response (XDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks4.6%
Microsoft Defender XDR4.2%
ReliaQuest GreyMatter0.9%
Other90.3%
Extended Detection and Response (XDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
Zaid bin junaid  - PeerSpot reviewer
Product Manager at Flash
Improved threat detection has reduced incidents and has automated investigations with AI
There are multiple features of ReliaQuest GreyMatter which I love personally. The agentic AI, which helps in autonomous investigation and containment, is multiplying the speed of the task to be done. Features such as managed service integration and MDR with human expertise when needed are some major features which I love about ReliaQuest GreyMatter.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Palo Alto is the core of the security infrastructure in the environment."
"One thing that I like about Cortex XDR by Palo Alto Networks, it is detecting all the suspicious or malicious binaries, and it has integration with Palo Alto Firewall."
"The product has an intuitive dashboard."
"Once you become familiar with it, Cortex XDR by Palo Alto Networks is a more powerful tool and I would say that I prefer it over MDE because it is a stronger tool for me."
"The initial setup isn't too bad."
"The initial setup is pretty easy."
"The best feature of Cortex XDR by Palo Alto Networks is that it collects logs from different sections such as the endpoint, the network, and the cloud, making it easy to investigate alerts, collect some of the investigation packages related to the infected machines, and provide live response."
"It's a perfect solution. It integrates well into the environment."
"The proactive remediation aspects and the surfacing of suspicious activity for investigation and escalation are the key aspects we appreciate most."
"The best feature is probably the alert generation. When I do a security reset, the other session triggers instantly from the Defender console, and I can work on it. The policies are three times, but they are also ready to install it."
"For me, the advanced hunting capabilities have been really great. It allowed querying the dataset with their own language, which is KQL or Kusto Query Language. That has allowed me to get much more insight into the events that have occurred. The whole power of 365 Defender is that you can get the whole story. It allows you to query an email-based activity and then correlate it with an endpoint-based activity."
"I like the easy integration and advanced possibilities. We can implement it at customer sites in a few clicks, but we can also dive deep and drill down to extended features. There's a very good starting point to get into this product and all the features from Defender."
"365 Defender saves us a lot of money because we don't have to recover data or hire outside lawyers to help us with legal trouble."
"The ability to integrate and observe a more cohesive narrative across the products is crucial."
"The most valuable features are machine learning, AI, and auto-remediation of none malicious alerts."
"From the perspective of Microsoft 365 XDR, the main benefit is a single, centralized dashboard offering the holistic visibility organizations crave."
"ReliaQuest GreyMatter saves around 60% of time or resources."
"ReliaQuest GreyMatter has helped us to reduce security incidents by 89%, which is a significant amount of incidents we have seen."
 

Cons

"The deployment is pretty hard."
"If they had pulse rate detection, it would be better."
"If you compare it to SentinelOne, which has more functionalities and detection capabilities on an open platform, the pricing on SentinelOne is far more reasonable and cheaper than Cortex XDR by Palo Alto Networks."
"The configuration could be simplified. I would like to see better protection, specifically to protect email applications."
"There's room for improvement with Mac device installations, which can be challenging."
"Data privacy is a matter of concern. You have to be careful with data privacy, it can be sensitive and Cortex can have most of your access."
"In terms of areas of improvement, we have not completed our review of the product. We're also looking at other products. So, it's a little bit hard to tell what could be different because we have not completed the review of this product, but based on our experience so far, its implementation is quite complex."
"It's more focused on network communication. If a customer wants to increase the level of protection and start working with documents, it's impossible to integrate these features into the system. It's more of a communication-oriented system than a content security-oriented system."
"Microsoft Defender XDR could be improved in terms of speed, especially backend speed."
"The support from Microsoft could improve. There are times I have to wait for a response from a qualified specialist."
"For some scenarios, it provides good visibility into threats, and for some scenarios, it doesn't. For example, sometimes the URLs within the emails have destinations, and you do get a screenshot and all further details, but it's not always the case. It would be good if they did a better job of enabling that for all the emails that they identified as malicious. When you get an email threat, you can go into the email and see more details, but the URL destination feature doesn't always show you a screenshot of the URL in that email. It also doesn't always give you the characteristics relating to that URL. It would be quite good if the information is complete where it says that we identified this URL, and this is what it looks like. There should be some threat intel about it. It should give you more details."
"We should be able to use the product on devices like Apple, Linux, etc."
"Automated playbooks and automated dashboards would be preferable to the way the data is currently being presented."
"The cost can be high if you want to build custom license packages. Another area for improvement is the policies. In Azure, we need to implement policies in JSON format, but in 365 Defender 365, it would be helpful to use a different format so we can customize the platform."
"The AI could be improved. As an analyst, I want to be able to interact more with AI. The AI simply sends summaries. I can't ask it, for example, if it has seen any suspicious activity with device two. I have to go and check device two for myself."
"Troubleshooting in Microsoft 365 Defender can be inefficient."
"Areas that have room for improvement include user interface and integration."
 

Pricing and Cost Advice

"Traps pays for itself within the first 16 months of a three-year subscription. This is attributed to OPEX savings, as security teams spent less time trying to identify and isolate malware for analysis as a result of a reduction in malware incidents, false positives, and breach avoidance."
"It is cost-effective compared to similar solutions. It fits for the small businesses through to the big businesses."
"Our license will require renewal in August, after which the maintenance will continue as usual."
"The pricing is okay, although direct support can be expensive."
"Very costly product."
"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"The tool's price is moderate."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"We've managed to navigate it effectively through our enterprise agreement, and Microsoft's academic discounts have proven to be quite generous."
"While Microsoft Defender XDR carries a higher cost, its ease of use compared to Defender may justify the investment."
"Purchasing Microsoft Defender XDR as part of a Microsoft 365 bundle can be cost-effective, but acquiring it as a standalone product may be more expensive."
"I find the pricing to be quite competitive, especially considering its inclusion in our E5 subscription, which provides a comprehensive set of functionalities."
"The solution is affordable, and we haven't been hit with any hidden costs. The subscription model is straightforward, and it's easy to understand how much additional features cost. If we need to cancel a license or feature, we do that well in advance to avoid being charged for it, but overall, the pricing and licensing are simple and easy."
"On average, we pay around 55 euros per user for the services and features we receive."
"They have moved from a licensing model to pay-per-use... The question is: What happens if, for any reason, there's not enough budget to accept this model? That could be a great problem."
"The functionality is fantastic, but for medium and small-sized companies it's overpriced. It would be better if it were a little bit cheaper."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
11%
Comms Service Provider
9%
Computer Software Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
7%
Financial Services Firm
11%
Manufacturing Company
9%
Construction Company
7%
Retailer
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise21
Large Enterprise52
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with ReliaQuest GreyMatter?
Areas that have room for improvement include user interface and integration.
What is your primary use case for ReliaQuest GreyMatter?
I use ReliaQuest GreyMatter for detection and response, XDR, and SIEM. The best features I like about GreyMatter the ...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Information Not Available
Find out what your peers are saying about Microsoft Defender XDR vs. ReliaQuest GreyMatter and other solutions. Updated: June 2026.
902,456 professionals have used our research since 2012.