Microsoft Defender for Office 365 vs Trellix Collaboration Security comparison

Microsoft and Trellix are both solutions in the Email Security category. Microsoft is ranked #2 with an average rating of 8.5, while Trellix is ranked #11 with an average rating of 8.7. Microsoft holds a 6.3% mindshare in Email Security, compared to Trellix’s 2.3% mindshare. Additionally, 96% of Microsoft users are willing to recommend the solution, compared to 100% of Trellix users who would recommend it.

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Executive SummaryUpdated on Dec 3, 2024

Trellix Collaboration Security and Microsoft Defender for Office 365 are key players in cybersecurity, specifically in the protection of collaborative environments. Microsoft Defender for Office 365 has an upper hand due to its wide-ranging features and cloud integration, albeit with a higher price. Trellix is more appealing to budget-conscious buyers with its pricing support.

Features: Trellix Collaboration Security offers strong threat detection, protection for collaboration tools, and robust data privacy controls. Microsoft Defender for Office 365 provides advanced threat protection, phishing detection, and seamless integration within the Microsoft ecosystem.

Room for Improvement: Trellix could enhance its integration capabilities beyond collaboration tools and provide more advanced threat analytics. It might also benefit from diversifying its feature set to match broader enterprise needs. Microsoft Defender for Office 365 may improve by simplifying its deployment in non-Microsoft environments, enhancing its cost-effectiveness, and offering more personalized customer support options.

Ease of Deployment and Customer Service: Trellix supports easy deployment with a focus on customer support and seamless integration with various collaborative tools. Microsoft Defender for Office 365 has an advantage through native integration with Microsoft products, which streamlines setup. However, its deployment can be more complex in diverse environments. Microsoft's customer service is efficient due to extensive resources, while Trellix offers a personalized support model.

Pricing and ROI: Trellix Collaboration Security provides competitive setup costs and favorable ROI, especially for organizations focused on collaboration tool security. Microsoft Defender for Office 365, despite a higher setup cost, offers extensive coverage that leads to significant ROI for businesses already utilizing Microsoft solutions. Trellix is preferred by budget-focused organizations, while Microsoft is valued for its feature richness.

To learn more, read our detailed Microsoft Defender for Office 365 vs. Trellix Collaboration Security Report (Updated: May 2026).

Buyer's Guide

Microsoft Defender for Office 365 vs. Trellix Collaboration Security

May 2026

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Helped 902,270 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cloudflare One

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.3%, down from 12.6% compared to the previous year. The mindshare of Trellix Collaboration Security is 2.3%, up from 2.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Email Security Mindshare Distribution
Product	Mindshare (%)
Microsoft Defender for Office 365	6.3%
Trellix Collaboration Security	2.3%
Cloudflare One	1.6%
Other	89.8%

Email Security

Featured Reviews

Cobe Van Coller

Network Architect at IP Dimension

Cloud security has improved remote access and has reduced costs for smaller client sites

I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.

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Emeka Ndulu

Cloud Solutions Architect at a tech services company with 201-500 employees

Improves threat visibility and response while reducing manual tasks and training users against phishing

I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

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Felipe Antoniazzi

Cyber Security Lead at a healthcare company with 10,001+ employees

Real-time threat response has boosted detection accuracy and reduces manual investigation work

I have had challenges in the past with Trellix Collaboration Security for implementation because of issues related to compatibility. Since we worked in a global company with different operating systems, it was necessary to create different plans and different actions to implement the product.One thing I really do not prefer in Trellix Collaboration Security is not related to the console. I am a McAfee fan since the McAfee tool, and I find the console of Trellix Collaboration Security to be very user-friendly and easy to use. However, I do not know if it is related to the architecture of the product. Of course, we have modern threats based on behaviors and zero days. We have today CrowdStrike and SentinelOne, where we have better results based on threats and behavior, where it is possible to create a simulation environment based on the file detected and based on it, confirm if it really is malicious or not. In general, I believe Trellix Collaboration Security improved the console based on the last console of McAfee, but I think it is possible to improve more. It really is a good product, but in my view, it needs to improve detection based on behaviors. Regarding automations, I have implemented Trellix Collaboration Security here at Johnson & Johnson, and I implemented it in the same situation at Santander Bank and BNP Paribas Bank, where I created automations to export data for different metrics, including malicious detections, compliance, baselines, scans, last scans based on the seven days, and checking of patterns. I export everything to CSV files. Based on that, I create Power BI dashboards, and in these Power BI dashboards, I have a more executive view for different metrics to provide to myself, my manager, or director to create an executive view based on it. Another important point we use here at Johnson & Johnson and other companies is a data hub or a SIEM solution, such as Elastic or ArcSight, where we select some logs to be sent and use it to build reports and metrics.

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Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"Clover is the best product globally."

"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."

"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."

"Cloudflare Access is part of the Zero Trust philosophy."

"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."

"We mostly use Cloudflare WAF, and gets basic Cloudflaire DDoS, caching as extra bonus . We like the factor these features are all integrated into 1 console, simple to manage."

"The blocking feature is very good."

"It will take the blow rather than our applications should an attack occur."

More Cloudflare One pros

"It has helped us in improving our security posture; it detects any kind of attack or abnormal behavior in accessing the system and sends an alert to the administrator who can check, understand, and review on time to ensure that all activities are legit."

"It gives us visibility into threats and, for endpoints, it helps us to prioritize threats. We used to have a lack of visibility, but now our time to detect and respond has decreased."

"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."

"Microsoft Defender for Office 365 has decreased my time to detection and time to respond by one hundred percent."

"The feature I like the most about Microsoft Defender for Office 365 is that it typically runs in the background—you do not know it is there until you need to access it."

"The email protection is excellent, especially in terms of anti-phishing policies."

"Microsoft Defender for Office 365's most valuable feature is its performance."

"Microsoft Defender for Office 365 is a cloud-based email filtering service that helps protect our organization against unknown malware and viruses by providing robust zero-day protection and includes features to safeguard our organization from harmful links in real-time."

More Microsoft Defender for Office 365 pros

"The accessibility is one of the features that I love; we can control it from the cloud and we can access it from anywhere."

"One of the most valuable features is the protection against vulnerabilities, particularly through virtual patching."

"The solution offers almost every feature that customers need in one solution, for example, spam filtering, antivirus, et cetera, with almost zero false positives."

"Trellix Collaboration Security has positively impacted my organization by improving security, making teamwork more effective, and ensuring collaboration has become smoother."

"The auto-remediation feature is valuable."

"I'd recommend the product due to the fact that it can stop most of the phishing and malicious items from getting through our email."

"FireEye Email Security helps us prevent spam and phishing emails and all other business-compromised email attacks."

"Trellix Collaboration Security has positively impacted our organization by making our collaboration environment very safe, allowing our team to share files and links without worrying about threats."

More Trellix Collaboration Security pros

Cons

"For the topic of improvement, providing some training material is one of my suggestions."

"Our customers no longer use Cloudflare because its service is subpar."

"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."

"The software has automated alerts, but the automated alerts are not available in the mobile app."

"The response time for support must be reduced."

"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."

"Feedback could be enhanced."

"The onboarding process can be improved a little bit."

More Cloudflare One cons

"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."

"Its price should be improved. Its cost is a major concern for us."

"I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware."

"The certification training for Defender for 365 needs to be deeper and incorporate Sentinel. I took all the security courses except one, and Sentinel isn't included."

"The pre-sales cost calculations could be more transparent."

"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."

"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."

"The phishing and spam filters could use some improvement."

More Microsoft Defender for Office 365 cons

"The solution must provide features to scan QR codes for threats."

"I chose a nine out of ten because some improvements are required, especially concerning East-West traffic or zero-day vulnerabilities."

"Sometimes especially zero-day spam emails can be passed to the user's inbox."

"I would like to see this solution become more flexible."

"In general, our company should make the tool more robust to protect our systems."

"I would rate them as a 1.5. The new hub created in India is not good."

"I observe that the return on investment is hindered by the lack of adequate training opportunities, with Trellix's own training being quite costly, ranging from 2,000 to 4,000 dollars, which many small or medium-sized businesses cannot afford."

"There is a need for improved integration with totally different products, such as a rapid server."

More Trellix Collaboration Security cons

Pricing and Cost Advice

"The prices are slightly expensive."

"The solution's pricing lacks transparency."

"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."

"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."

"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."

"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."

"The solution is not that expensive."

"Cloudflare Zero Trust Platform's pricing is good."

"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."

"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."

"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."

"The pricing has become expensive."

"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."

"The product is expensive."

"From the pricing point of view, like any other product in the market, there is scope for negotiation."

"The license is expensive because the cost is based on the number of users."

More Microsoft Defender for Office 365 pricing and cost advice

"The solution requires a license to be purchased for every user."

"I rate the product price as nine out of ten, where ten is the most expensive, and one is the cheapest. There is no need to pay any extra charges apart from the licensing costs."

"The licensing is on a yearly basis."

"The cost is very high."

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Top Industries

By visitors reading reviews

Construction Company

19%

Comms Service Provider

10%

Financial Services Firm

Manufacturing Company

Computer Software Company

12%

Manufacturing Company

Financial Services Firm

Comms Service Provider

Construction Company

15%

Manufacturing Company

14%

Healthcare Company

12%

Comms Service Provider

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	10
Midsize Enterprise	1
Large Enterprise	12

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	11
Large Enterprise	32

By reviewers
Company Size	Count
Small Business	15
Midsize Enterprise	5
Large Enterprise	15

Questions from the Community

What is your experience regarding pricing and costs for Cloudflare Zero Trust Platform?

Pricing is competitive. Akamai is more expensive, in my view.

See all answers

What needs improvement with Cloudflare Zero Trust Platform?

In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...

See all answers

What is your primary use case for Cloudflare Zero Trust Platform?

Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...

See all answers

What is your experience regarding pricing and costs for Microsoft Defender for Office 365?

My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...

See all answers

What needs improvement with Microsoft Defender for Office 365?

I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...

See all answers

What is your primary use case for Microsoft Defender for Office 365?

My main use cases for Microsoft Defender for Office 365 include email hygiene.

See all answers

What needs improvement with FireEye Email Security?

I believe no improvements are needed for Trellix Collaboration Security as we are already using more tools from Trell...

See all answers

What is your primary use case for FireEye Email Security?

My main use case for Trellix Collaboration Security is to protect our platforms like Slack, Microsoft Teams, Google W...

See all answers

What advice do you have for others considering FireEye Email Security?

My advice for others looking into using Trellix Collaboration Security is to prevent insider threat vectors because a...

See all answers

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Twingate vs Cloudflare One

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FortiSASE vs Cloudflare One

Compared 3% of the time

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Proofpoint Email Protection vs Microsoft Defender for Office 365

Compared 6% of the time

Mimecast Advanced Email Security vs Microsoft Defender for Office 365

Compared 5% of the time

Check Point Email Security (formerly Harmony Email & Collaboration) vs Microsoft Defender for Office 365

Compared 5% of the time

Cisco Secure Email vs Microsoft Defender for Office 365

Compared 3% of the time

Barracuda Email Protection vs Microsoft Defender for Office 365

Compared 3% of the time

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Cisco Secure Email vs Trellix Collaboration Security

Compared 59% of the time

Mimecast Advanced Email Security vs Trellix Collaboration Security

Compared 5% of the time

MetaDefender Email Security Solutions vs Trellix Collaboration Security

Compared 4% of the time

Barracuda Email Security Gateway vs Trellix Collaboration Security

Compared 4% of the time

Fortinet FortiMail vs Trellix Collaboration Security

Compared 3% of the time

More Trellix Collaboration Security Competitors

Product Reports

Buyer's Guide

Cloudflare One

June 2026

Download Cloudflare One product report

Buyer's Guide

Microsoft Defender for Office 365

June 2026

Microsoft Defender for Office 365 report

Download Microsoft Defender for Office 365 product report

Buyer's Guide

Trellix Collaboration Security

May 2026

Download Trellix Collaboration Security product report

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform

MS Defender for Office 365

FireEye Email Security

Overview

Cloudflare One is a comprehensive platform for security, performance, and connectivity. It provides features like rate limiting, DDoS protection, and application access, tailored to enhance user experience while securing internet access and accelerating communications.

Designed to integrate security measures with ease of use and scalability, Cloudflare One offers a secure web gateway and zero trust network access. These features ensure seamless setup and operation, making connectivity reliable and protected. Users appreciate its integrated console, intuitive interface, and the ability to manage risk effectively. It offers straightforward deployment, improves latency, and boasts cost-effectiveness. While its onboarding process and documentation need enhancement, its value in content delivery and application shielding is notable. Despite challenges in integrating Cloudflare Access with existing VPNs and the need for better automation and support, it remains vital for DNS and infrastructure protection.

What features make Cloudflare One stand out?

Rate Limiting: Controls the traffic rate to prevent abuse.
DDoS Protection: Shields applications from distributed denial-of-service attacks.
Secure Web Gateway: Provides secure internet access with seamless operation.
Zero Trust Network Access: Ensures secure, application-based connectivity without relying on traditional VPNs.
Access for Connectivity: Facilitates access to internal applications securely.

What benefits should users look for in reviews?

Security: Robust measures for DNS and browsing protection.
Performance: Enhanced site accessibility and communication speed.
Cost-Effectiveness: Offers competitive pricing for its features.
Ease of Deployment: Straightforward and efficient setup process.

In industries like finance, retail, and technology, Cloudflare One is crucial for enabling secure remote access and protecting web applications against dynamic threats. It supports compliance access policies and enhances content delivery, playing a key role in safeguarding digital infrastructure.

Cloudflare

Microsoft Defender for Office 365 offers real-time email security, enhancing threat detection through integration within the Microsoft ecosystem. Its user-friendly interface and central management streamline operations, providing robust protection against phishing, ransomware, and malware.

Defender for Office 365 is focused on efficiently securing email communication by safeguarding against phishing, malware, and spam threats. With its strong integration with other Microsoft services, it is tailored to improve endpoint security and identity protection. Its centralized management tools simplify threat prioritization, while the automated threat response capabilities ensure swift actions against potential risks. Organizations leverage its capabilities to efficiently manage their cybersecurity efforts, particularly in remote work environments, while maintaining a secure system across Office 365 applications and Azure-hosted services.

What are the key features?

Real-time Email Protection: Continuously monitors and protects email communications.
Safe Attachments and Links: Scans attachments and links for potential threats.
Anti-Phishing Measures: Provides tools to detect and block phishing attempts.
Integration with Microsoft Services: Seamlessly connects with other Microsoft applications for enhanced security.
Automated Threat Responses: Activates immediate responses to detected threats.

What benefits should users expect from reviews?

Time Savings: Automates processes to reduce manual threat management efforts.
Improved Cybersecurity: Strengthens organizational defenses against various cyber threats.
Efficient Remote Work: Enhances protection for remote teams and virtual collaborations.
Comprehensive Coverage: Extends protection across Office 365 and Azure services.

Implementations of Defender for Office 365 vary across industries, optimizing email security for sectors such as finance, healthcare, and education. In finance, it aids in protecting sensitive financial data from phishing and fraud. Healthcare benefits from secure communications, ensuring patient data privacy. Educational institutions use it to maintain secure virtual learning environments against cyber threats.

Microsoft

Trellix Collaboration Security enhances communication platforms with robust protective measures, utilizing threat intelligence, secure file sharing, customizable dashboards, and cloud compatibility. Its design fosters real-time threat prevention with features like deep packet inspection and automatic mail scans.

Established to secure communications, Trellix Collaboration Security employs advanced technologies like GTI threat intelligence and SSL to ensure data safety. Users benefit from real-time threat detection, streamlined cloud integration, and a responsive interface. Its functionalities include automatic email scanning, firewall and anti-spam capabilities that build a reliable security infrastructure revered for its scalability and straightforward deployment. Trellix also integrates threat intelligence tools and enhances control over security operations, encouraging efficient prevention strategies.

What are the essential features of Trellix Collaboration Security?

GTI Threat Intelligence: Provides insights into potential threats.
Deep Packet Inspection: Examines data packets to detect malicious activities.
Secure File Sharing: Facilitates secure exchanging of files.
Customizable Dashboards: Offers adaptable views for tailored monitoring.
Automatic Mail Scans: Identifies and filters threats in emails.

Which benefits and ROI should be considered?

Real-Time Threat Response: Ensures immediate action against detected threats.
Cloud Platform Compatibility: Supports hybrid environments for flexible operations.
Scalability: Adapts to the growing security needs without compromising efficiency.
User-Friendly Interface: Enhances user interaction and ease of use.

In distinct industries like finance and healthcare, Trellix Collaboration Security plays a crucial role in ensuring email protection and secure data exchange. It helps these sectors combat threats like phishing and unauthorized access by leveraging advanced scanning methods and integrating management tools such as LDAP. Organizations value its ability to safeguard network communications and manage large-scale endpoints effectively, whether on-premise or in the cloud. The solution's customization and configuration capabilities allow tailored implementations, ensuring optimal protection across diverse operational needs.

Trellix

Sample Customers

23andMe

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.

Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market

Buyer's Guide

Microsoft Defender for Office 365 vs. Trellix Collaboration Security

May 2026

Free Report: Microsoft Defender for Office 365 vs. Trellix Collaboration Security

Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Collaboration Security and other solutions. Updated: May 2026.

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See our Microsoft Defender for Office 365 vs. Trellix Collaboration Security report.

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We monitor all Email Security reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.