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Microsoft Defender for Office 365 vs Morphisec comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
53
Ranking in other categories
Email Archiving (1st), Email Security (1st), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Morphisec
Ranking in Advanced Threat Protection (ATP)
34th
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
21
Ranking in other categories
Vulnerability Management (64th), Endpoint Protection Platform (EPP) (54th), Endpoint Detection and Response (EDR) (61st), Cloud Workload Protection Platforms (CWPP) (31st), Threat Deception Platforms (15th)
 

Mindshare comparison

As of October 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 7.7%, down from 12.1% compared to the previous year. The mindshare of Morphisec is 1.2%, up from 0.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3657.7%
Morphisec1.2%
Other91.1%
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Rick Schibler - PeerSpot reviewer
Offers in-memory protection at a lower price than competitors
Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
"It gives us visibility into threats and, for endpoints, it helps us to prioritize threats. We used to have a lack of visibility, but now our time to detect and respond has decreased."
"The deployment capability is a great feature."
"Microsoft Defender has a feature to protect each and every attachment. Even if it's an encrypted attachment, it will check for any potential threats."
"The initial setup was easy."
"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"Morphisec makes use of deterministic attack prevention that doesn’t require investigation of security alerts. It changes the memory locations of where certain applications run. If you think of Excel, opening a PDF, running an Excel macro, or opening a webpage and clicking on a link, all of those actions run in a certain area of memory. Morphisec changes the memory locations of where those run."
"I really like the integration with Microsoft Defender. In addition to having third-party endpoint protection, we're also enabling Defender... I like the reporting that we get from Defender, when it comes in. I like that it's one console showing both Morphisec and Defender where it provides me with full visibility into security events from Defender and Morphisec."
"Morphisec provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. Defender and Morphisec are integrated. It's important because it lowers the total cost of maintenance on the engineer's time, more or less. So the administrative time is dramatically reduced in maintaining the product. This saves an engineer around four to five hours a week."
"Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it."
"Morphisec has absolutely helped save money on our security stack. The ransomware at the end of the day can cost organizations millions upon millions of dollars. Investing in tools like Morphisec is a great reduction in that cost. If I can spend $10,000 in a year to protect assets that could be ransomed for $20,000,000, that's definitely a bet that one should pursue. Morphisec absolutely it's worth the investment."
"It provides full visibility into security events and from both solutions in one dashboard. I'm not a big security guy, if I have a threat that looks like there's a problem, I will ask Morphisec to dissect it for me, and tell me what might be happening. Because it tends to be all hash codes, so I can tell what's going on. They've been pretty good with that."
"Morphisec stops attacks without needing to know what type of threat it is, just that it is foreign. It is based on injections, so it would know when a software launches. If a software launches and something else also launches, then it would count that as anomalous and block it. Because the software looks at the code, and if it executes something else that is not related, then Morphisec would block it. That is how it works."
"Morphisec is a straightforward solution that is efficient and very stable."
 

Cons

"There is a different console for different things; I just want one consolidated console."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"There needs to be an improvement in integrating the product to work across multiple operating systems, and to have better support for non-Microsoft file types."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"The product must provide better malware detection."
"In the areas of improvement for Microsoft Defender for Office 365, the console is the biggest challenge for me."
"Microsoft Defender for Office 365 must improve the overall management style, including the GUI. It also needs to change the filters so that it is easy to whitelist and blacklist data."
"We started in the Linux platform and we deployed to Linux. The licensing of that has been kind of confusing between Linux licensing and Windows licensing. The overall simplicity of licensing or offering an enterprise license to just cover everything and then we don't have to count needs improvement."
"Those are some of the features that I was looking for on my on-prem platform that they've already instituted in the cloud and that I'm sure will be instituting on their on-prem platform as well. Having to have an on-prem server required a lot of administration. Being able to push that to the cloud and have it managed up there for us is a real nice addition."
"We sometimes have to depend on the support team to know what action we should take. If the solution for an alert can be built into the report that we are getting, it will save time, and the interaction with support would be less. At times, corrective action is required, but at times, we don't need to take any action. It would be good if we get to know in the report that a particular infection doesn't require any action. It will save us time and effort."
"The weakest point of this product is how difficult it is to understand the reasons for an alert. This is a problem because it is hard to determine whether an attack is real or not."
"I haven't been able to get the cloud deployment to work. When there's an update, I'm supposed to be able to roll it out for the cloud solution, but right now I'm continuing to use our SCCM solution to update it."
"From a company standpoint, a little more interaction with the customers throughout the year might be beneficial. I would like check-ins from the Morphisec account executives about any type of Morphisec news as well as a bit more interaction with customers throughout the year to know if anything new is coming out with Morphisec, e.g., what they are working on in regards to their development roadmap. We tend not to get that up until the time that we go for a yearly renewal. So, we end up talking to people from Morphisec once a year, but it is usually at renewal time."
"Sometimes it generates false positive alerts. They need to continue working on that. They have provided solutions for it and have fixed issues with updated versions. The service is quite good but they need to work on it more so that there are no false positive alerts."
"We wanted to have multi-tenants in their cloud platform, so every entity can look into their own systems and not see other systems in other entities. I have a beta version on that now. I would like them to incorporate that in the cloud solution."
 

Pricing and Cost Advice

"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The product is expensive."
"The pricing is normal. Considering its popularity, it's not overpriced."
"The product is very expensive."
"The license is expensive because the cost is based on the number of users."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"The pricing has become expensive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."
"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."
"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."
"The pricing is definitely fair for what it does."
"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."
"Our licensing is tied into our contract. Because we have a long-term contract, our pricing is a little bit lower. It is per year, so we don't get charged per endpoint, but we do have a cap. Our cap is 80 endpoints. If we were to go over 80, when we renewed our contract, which is not until three years are over. Then, they would reevaluate, and say, "Well, you have more than 80 devices active right now. This is going to be the price change." They know that we are installing and replacing computers, so the numbers will be all over the place depending on whether you archive or don't archive, which is the reason why we just have to keep up on that stuff."
"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."
"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Outsourcing Company
16%
Manufacturing Company
12%
Computer Software Company
9%
Financial Services Firm
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise8
Large Enterprise27
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise8
Large Enterprise8
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download. VirusTotal helps to identify viruses, malware, troja...
Ask a question
Earn 20 points
 

Also Known As

MS Defender for Office 365
Morphisec, Morphisec Moving Target Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Morphisec and other solutions. Updated: September 2025.
869,566 professionals have used our research since 2012.