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Microsoft Defender for Office 365 vs Morphisec comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
53
Ranking in other categories
Email Archiving (1st), Email Security (1st), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Morphisec
Ranking in Advanced Threat Protection (ATP)
35th
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
21
Ranking in other categories
Vulnerability Management (64th), Endpoint Protection Platform (EPP) (53rd), Endpoint Detection and Response (EDR) (60th), Cloud Workload Protection Platforms (CWPP) (33rd), Threat Deception Platforms (17th)
 

Mindshare comparison

As of August 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 8.0%, down from 13.2% compared to the previous year. The mindshare of Morphisec is 1.1%, up from 0.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Rick Schibler - PeerSpot reviewer
Offers in-memory protection at a lower price than competitors
Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."
"The stability of Microsoft Defender for Office 365 is fantastic."
"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"We have seen it successfully block attacks that a traditional antivirus did not pick up."
"All the alerts are on the dashboard, which is quite simple and useful for us. You can easily check all the alerts that are being blocked or allowed, or whatever the action is. You can easily see that and you can take the necessary actions. You can add a PowerShell extension or any activities for blocking at your network level or for endpoints."
"We don't have to do anything as a user or as an admin. It does everything by default with its coding and inbuilt AI-based intelligence. We don't have to instruct it about what to do. It automatically takes corrective actions and quarantines or deletes a virus, malware, etc. That is the best part that I like about it."
"Morphisec is a straightforward solution that is efficient and very stable."
"Morphisec provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. Defender and Morphisec are integrated. It's important because it lowers the total cost of maintenance on the engineer's time, more or less. So the administrative time is dramatically reduced in maintaining the product. This saves an engineer around four to five hours a week."
"Morphisec makes use of deterministic attack prevention that doesn’t require investigation of security alerts. It changes the memory locations of where certain applications run. If you think of Excel, opening a PDF, running an Excel macro, or opening a webpage and clicking on a link, all of those actions run in a certain area of memory. Morphisec changes the memory locations of where those run."
"Morphisec makes it very easy for IT teams of any size to prevent breaches of critical systems because of the design of their tool. When we evaluated Morphisec, the CIO and I sat and listened. What attracted us to them is the fact that it stops activity at the point of detection. That saves a lot of time because now we are not investigating and trying to trace down what to turn off. We have already prevented it, which makes it very much safer and more secure."
"Morphisec Guard enables us to see at a glance whether our users have device control and disk encryption enabled properly. This is important because we are a global company operating with multiple entities. Previously, we didn't have that visibility. Now, we have visibility so we can pinpoint some locations where there are machines that are not really protected, offline, etc. It gives us visibility, which is good."
 

Cons

"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"We still see many false positives from time to time with Microsoft Defender for Office 365, so it would be good if we can reduce those false positives and provide better workflows for our end users, as sometimes they may not know what to do when they encounter a false positive."
"I think that Microsoft Defender for Office 365 could be improved if it could use VirusTotal to compare the programs or anything that I download."
"The pre-sales cost calculations could be more transparent."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"We sometimes have to depend on the support team to know what action we should take. If the solution for an alert can be built into the report that we are getting, it will save time, and the interaction with support would be less. At times, corrective action is required, but at times, we don't need to take any action. It would be good if we get to know in the report that a particular infection doesn't require any action. It will save us time and effort."
"Right now, it's just their auto-update feature. I know they are currently working on that. When they release a new version of the threat prevention platform, I do have to update that, rolling out to every computer. They have said, "From version 5, you would be able to do an auto-update." While this is very minor, that is the only thing that I would say needs to be upgraded. It would just make life a lot easier for other IT teams. However, I have simplified the process, so all I need to do is just download one file."
"I haven't been able to get the cloud deployment to work. When there's an update, I'm supposed to be able to roll it out for the cloud solution, but right now I'm continuing to use our SCCM solution to update it."
"We wanted to have multi-tenants in their cloud platform, so every entity can look into their own systems and not see other systems in other entities. I have a beta version on that now. I would like them to incorporate that in the cloud solution."
"The dashboard is the area that requires the most improvement. We have about, I would say 5,500 computers currently, and searching through all of those takes some time to filter. So as soon as you apply the filter, it takes a few seconds. It crunches, it thinks, and then it brings up the clients that match."
"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."
"It would be nice if they could integrate Morphisec with other traditional antivirus solutions beyond Microsoft Defender. That is probably my biggest gripe."
"We have discovered some bugs in the new releases that they've had to fix, so I would like to see more testing and QA on their side before they release."
 

Pricing and Cost Advice

"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"The license is expensive because the cost is based on the number of users."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The pricing has become expensive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Our licensing is tied into our contract. Because we have a long-term contract, our pricing is a little bit lower. It is per year, so we don't get charged per endpoint, but we do have a cap. Our cap is 80 endpoints. If we were to go over 80, when we renewed our contract, which is not until three years are over. Then, they would reevaluate, and say, "Well, you have more than 80 devices active right now. This is going to be the price change." They know that we are installing and replacing computers, so the numbers will be all over the place depending on whether you archive or don't archive, which is the reason why we just have to keep up on that stuff."
"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."
"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."
"It does not have multi-tenants. If South Africa wants to show only the machines that they have, they need their own cloud incidence. It is not possible to have that in a single cloud incidence with multiple tenants in it, instead you need to have multiple cloud incidences. Then, if you have that, it will be more expensive. However, they are going to change that, which is good."
"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."
"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."
"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."
"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Outsourcing Company
15%
Manufacturing Company
11%
Computer Software Company
10%
Financial Services Firm
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published. It's essential to enhan...
Ask a question
Earn 20 points
 

Also Known As

MS Defender for Office 365
Morphisec, Morphisec Moving Target Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Morphisec and other solutions. Updated: July 2025.
865,384 professionals have used our research since 2012.