Try our new research platform with insights from 80,000+ expert users

Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jul 27, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco HyperFlex HX-Series [...
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
90
Ranking in other categories
No ranking in other categories
Nutanix Cloud Infrastructur...
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
199
Ranking in other categories
Software Defined Storage (SDS) (5th), HCI (4th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)
 

Featured Reviews

Nuno Mendes - PeerSpot reviewer
High performance solution that makes it easy to efficiently manage VM resources
In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).
MahendraPanchotiya - PeerSpot reviewer
Offers a unified platform, reduces downtime, and simple updates
Nutanix offers a unified platform for managing databases, virtual machines, and applications. This simplifies management by consolidating everything into a single interface. While Nutanix may have a higher upfront cost compared to other hypervisors, it can significantly reduce the resources needed for infrastructure management. With our previous hypervisor, we needed nearly ten IT personnel. Nutanix has allowed us to streamline our team to just three members. We use a combination of database technologies, including SQL databases and web servers such as IIS, BHP, and NGINX. Nutanix features helped our organization reduce downtime. I don't recall the last time we had downtime related to Nutanix because it is such a stable product. Nutanix, a reliable product, helps us streamline our processes, which in turn improves company revenue. We began to see the benefits after two years, with a 40 percent reduction in operational costs. We migrated 200 servers from AWS to Nutanix. Nutanix may not consolidate applications, but it helps us run them more efficiently on its platform. Updating is simple with one click. I would rate the updating processes 10 out of 10. Adding compute and storage on demand is not difficult. However, we need to factor in the existing and new firmware and software requirements.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The initial setup is easy."
"The most valuable feature was the backup - it was easy to back up. It was also very easy to administrate and manage the system; much easier and faster. Finally, it was easy to extend the disk capacities."
"The initial setup is very straightforward."
"The ease of use and the graphical user interface (GUI) are two of the most valuable features of this solution."
"The initial setup was straightforward. With our partners and the consultancy that we had, we knew what we wanted to do. Therefore, we didn't have any problems with the installation and parametrization."
"When we use it for VDI solutions, it is very easy to deploy and support."
"The feature that we are most interested in is the scalability. When needed, we are able to add more nodes and scale it up further."
"It is a stable and scalable solution."
"It is a good solution and it is easy to work on their platform."
"Acropolis AOS's networking concept is excellent."
"Their Google operating system is more mature, so their results are much better."
"The ease of deployment is very good."
"The most valuable features are simple management and one-click upgrades."
"Regarding Nutanix AOS, fault tolerance is great."
"Acropolis AOS is scalable to nodes and the cloud."
"Nutanix Acropolis AOS is flexible and has helped people to work from home during the pandemic."
 

Cons

"We'd like the product to offer better integration with other products."
"Technical support is very good. Not excellent, but good. There's still not enough data available on the web. For example, for the integration to VMware, I had a case recently and I searched for more information but didn't find any."
"The product needs work in the area of deduplication which currently is inefficient."
"They should give us a little more information about how to use the CLI and offer more commands."
"If we compare it with VMware, the VMware product is basically very open, and it can be easily integrated with any platform. VMware product is also available on the cloud and is not an appliance-based product, whereas Cisco HyperFlex is an appliance-based product. Companies that want to use HCI as a platform or as a service would prefer something without an appliance. A SaaS-based product is better for a customer who is using the cloud and has multiple resources, workflows, and devices on the cloud and wants to go for a hyper-converged solution. This is where improvement is needed. In addition to an appliance-based product, Cisco should provide a SaaS-based product. Its price should be lower. Cisco needs to work on the pricing model for this product. Its price is a big road blocker when competing against Nutanix and VMware, which are its main competitors."
"Sometimes when there are multiple technologies involved in a support case, this is when there is a bit of a lag."
"The initial setup of profiles and templates could be improved. Maybe some end profiles that you can use based on your type of deployment would be good."
"The infrastructure team thinks that there are a lot of issues."
"They need to improve the look and feel of the interface. The functionality is fine, but the appearance could be better."
"There is a need is to be able to consume Nutanix storage from outside the cluster for other, non-Nutanix workloads."
"In the future, I would like Acropolis to add support for publishing external storage."
"In the future, I would like to see multi-tenancy in Nutanix Acropolis AOS."
"I would like better integration of XenServer into the AOS and Prism Central."
"The solution has more features than required"
"I feel like the flow chart and the automated processes have some room for improvement. They're nearly there, and the rest is fine. They've improved a lot over the past few years."
"It's lacking in some features but overcompensating in others."
 

Pricing and Cost Advice

"Pricing is better if you buy more Cisco products."
"I would like a clearer licensing model. It should explain a bit more what you receive if you buy the more expensive license rather than the standard one."
"It is highly priced compared to other vendors."
"Here in Brazil... it is very expensive. It's very hard for almost all companies to buy even the small version of this solution."
"It's roughly $30,000 per Hyperflex license, so that would be about $60,000 a year."
"The product could be cheaper."
"We negotiated with Cisco and we got some price benefit from that."
"There is a 30 percent additional premium that all the companies are charging for Cisco HyperFlex HX-Series because of the lack of chips and bottlenecks in the market. The cost of the solution is high right now."
"It is slightly more expensive compared to a standard, on-prem, bare-metal configuration. There is about a 30 percent overhead there."
"It's a bit expensive, but it's worth it."
"Our licensing fee on the total setup up was about R900 000."
"NCI is quite expensive compared to other products. It would help us if Nutanix considered affordability when releasing new products. We have an annual license and are considering extending it for another year."
"There is a license required for this solution and my clients usually purchase a two-year license with extended support. The price of the solution could be reduced, it is more expensive than competitors."
"The product’s licensing fee is moderately expensive."
"I know Nutanix and VxRail have similar prices and licenses. Nutanix is a go-ahead if AHV is used as hypervisor because it is already embedded in the price."
"They should lower the price. If they did they would fall into a more competitive market because the price does scare a lot of potential customers away when they get the quote."
report
Use our free recommendation engine to learn which HCI solutions are best for your needs.
867,676 professionals have used our research since 2012.
 

Comparison Review

it_user244362 - PeerSpot reviewer
Aug 30, 2015
Nutanix vs. VMware EVO:RAIL vs. FlexPod
Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…
 

Answers from the Community

NC
Aug 2, 2022
Aug 2, 2022
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrat...
See 2 answers
Oct 17, 2021
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.
Steffen Hornung - PeerSpot reviewer
Aug 2, 2022
With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.
 

Top Industries

By visitors reading reviews
Computer Software Company
18%
Financial Services Firm
9%
Government
8%
Manufacturing Company
7%
Computer Software Company
17%
Financial Services Firm
9%
Manufacturing Company
8%
Government
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise17
Large Enterprise57
By reviewers
Company SizeCount
Small Business91
Midsize Enterprise76
Large Enterprise82
 

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...
How does VxRail compare with Cisco HyperFlex HX Series?
VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...
What is the biggest difference between Nutanix Acropolis and VMware vSphere?
We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...
Which would you choose - Nutanix Acropolis AOS or VMware vSAN?
We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...
What makes Nutanix Cloud Infrastructure (NCI) worth using?
NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...
 

Also Known As

No data available
Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis
 

Overview

 

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest
St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.
Find out what your peers are saying about Dell Technologies, VMware, Nutanix and others in HCI. Updated: September 2025.
867,676 professionals have used our research since 2012.