Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

Cisco and Nutanix are both solutions in the HCI category. Additionally, 89% of Cisco users are willing to recommend the solution, compared to 94% of Nutanix users who would recommend it.

Cisco HyperFlex HX-Series [...

Read 90 Cisco HyperFlex HX-Series [EOL] reviews

89% willing to recommend

Nutanix Cloud Infrastructur...

Read 200 Nutanix Cloud Infrastructure (NCI) reviews

14,323 Views
7,305 Comparison Views

94% willing to recommend

Cisco HyperFlex HX-Series [...

Nutanix Cloud Infrastructur...

Comparison Buyer's Guide

Download the report

Executive SummaryUpdated on Nov 2, 2025

Nutanix Cloud Infrastructure (NCI) and Cisco HyperFlex HX-Series are leaders in hyper-converged infrastructure solutions, competing in enterprise IT environments. NCI seems to have an edge in ease of management and cost-effectiveness, whereas HyperFlex stands out with its strong integration and high availability.

Features: NCI boasts high performance, ease of administration, and seamless integration with its distributed file system. Valued features include data protection, storage auto-tiering, and one-click upgrades. HyperFlex, however, integrates compute, storage, and network, excelling in its ability to integrate with Cisco’s network solutions and offers robust support for various hypervisors, with high availability being a notable strength.

Room for Improvement: NCI could improve network switch convergence, DRC solutions, and enhance built-in backup features, with demands for a more user-friendly interface. HyperFlex's scalability options require enhancement, along with integration tools for external solutions, and users have highlighted the high cost and complexity as deterrents. Better analytics and cloud integration would benefit HyperFlex further.

Ease of Deployment and Customer Service: NCI enables rapid deployment with its intuitive interface and outstanding technical support, consistently appreciated for responsiveness and expertise. HyperFlex's deployment, while effective, can seem complex, with a need for better guidance and documentation. Cisco’s comprehensive support is perceived as slightly less agile than Nutanix, affecting the customer service experience.

Pricing and ROI: NCI is seen as cost-effective, benefiting deployment and operational expenses through inclusive features and reduced infrastructure needs, contributing to faster ROI. Nutanix’s licensing simplicity is favored, albeit with notable upfront costs. HyperFlex, with a higher initial cost, is justified by its integrations and support, although annual subscription costs and licensing complexities suggest areas for improvement.

To learn more, read our detailed HCI Report (Updated: December 2025).

Buyer's Guide

HCI

December 2025

Download the complete report

Helped 880,844 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cisco HyperFlex HX-Series [...

Average Rating

8.0

Reviews Sentiment

6.7

Number of Reviews

Ranking in other categories

No ranking in other categories

Nutanix Cloud Infrastructur...

Average Rating

8.6

Reviews Sentiment

7.3

Number of Reviews

200

Ranking in other categories

Software Defined Storage (SDS) (6th), HCI (5th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)

Featured Reviews

reviewer2133501

Assistant VP, Information Technology at a financial services firm with 1,001-5,000 employees

Effective deduplication feature, but lacks a unified architecture

Cisco HyperFlex HX-Series could be improved by reducing the number of nodes. Currently, the architecture separates data, computing, memory, and storage into different parts. For example, if I need around 200 servers with a requirement of TB of storage, I would need 200 clusters, which can be quite cumbersome. Other solutions like Dell and Nutanix have a single combined unit that includes computing, memory, and storage, which can reduce the number of nodes required and also reduce licensing and power consumption. Therefore, I suggest improving the architecture of the Cisco HyperFlex HX-Series by combining computing, memory, and storage into a single unit, making it more efficient and easier to manage. It will also reduce the number of nodes required and licensing costs and help to reduce power consumption. I would like to see improved internal integration capabilities in the next release. Currently, it is constrained only to VMware only. So, there is no integration part of the RAC or IEL or anything, and it isn't easy to manage it. If I want to hold another partner, then that part will not be possible. So, you have to manage that particular integration. Another feature could be in terms of memory usage.

Read full review

Obasanjo Biliaminu

Head Systems Administration/Security at Nigeria Inter-Bank Settlement System PLC

Infrastructure efficiency has improved significantly with quick server provisioning, though physical to virtual migrations need a streamlined in-house tool

From my experience with Nutanix Cloud Infrastructure (NCI), there is one area that needs improvement. When moving a critical infrastructure from a physical machine to Nutanix Cloud Infrastructure (NCI), we currently have to use a third-party tool to convert the physical machine to a VM. We have to use VMware converter to perform this conversion before moving it to Nutanix Cloud Infrastructure (NCI). I would suggest that Nutanix Cloud Infrastructure (NCI) should develop their own P2V (physical to VM) tools instead of requiring users to rely on third-party solutions.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The product is easy to manage and flexible for upgrading without major changes."

"On the VDI side, because the storage is local to the HyperFlex, it was very easy and convenient. The performance is exceptional."

"The automation is a valuable feature, it's interesting."

"The most valuable feature is that you can manage the whole cluster from the traffic interconnect."

"The feature that we are most interested in is the scalability. When needed, we are able to add more nodes and scale it up further."

"It is a hyper-converged solution which integrates with the network instead of the product."

"The integration between the storage and the server applications is the most valuable feature of this solution. It cuts down on the necessity to buy a secondary storage system.. It saves money in the long-run."

"I find the usability very valuable."

More Cisco HyperFlex HX-Series [EOL] pros

"Nutanix Cloud Infrastructure's most valuable features are all the cloud facilities or benefits it provides for my data center."

"It is very easy to clone systems using the solution."

"Hyperconverged Infrastructure is the most valuable feature of Nutanix Cloud Infrastructure."

"The solution is very stable. We haven't had any issues."

"Nutanix has the best virtual desktop infrastructure."

"The solution offers impressive performance."

"Data locality provides super-fast data access and ultra-low latency."

"The solution is easy to use and the pricing is affordable."

More Nutanix Cloud Infrastructure (NCI) pros

Cons

"Maybe a better version is required to gather all of the information to allow HyperFlex to bring everything online more rapidly."

"There are sometimes issues with memory failure."

"Cisco is a bit more challenging in terms of deployment. The admin must be knowledgeable in order to complete the task. Without that knowledge, it will be difficult to complete."

"I would like to see more analytics. It could use better infographs in the HyperFlex Connect on how traffic is running in the network. If you were reaching any capacity issues on the Fabric Interconnects, it should be able to cool all of the servers and Fabric Interconnects, then possibly integrate it with, e.g., Nexus Series switches. This should all be available in a single pane of glass."

"Sometimes when there are multiple technologies involved in a support case, this is when there is a bit of a lag."

"We are operating two clusters for site resiliency. I would like to support running redundant/resilient vCenter server instances on each rather than a supported external server."

"The problem is that we always have to keep an eye out for new releases to make sure that the version we're running is up-to-date."

"Cisco's technical support originally was outstanding, but it has declined over the last 12 months. I've heard they're trying to do better, but I haven't been overly impressed with their support recently for HyperFlex."

More Cisco HyperFlex HX-Series [EOL] cons

"In the future, I would like to see integration with external storage using the fiber channel"

"The product could be improved with more security. The product needs a bit more experience in the market. I think you don't have the possibility to add other hardware. It could be improved with the ability to add and extend."

"There is a need is to be able to consume Nutanix storage from outside the cluster for other, non-Nutanix workloads."

"While the customer support is truly incredible, for Spanish speakers it would be appropriate to have support in their native language to further improve problem-solving conditions."

"I would like to see a fuller integration with the public cloud. It would help the user enter the hybrid cloud infrastructure."

"The licenses for Nutanix are very complicated."

"In Thailand, there really isn't a cloud version of Nutanx available to us."

"One of the improvements I would like to have is related to naming. It is getting confusing because they are using three-letter acronyms, which are more or less misleading. What I do not like is that they changed names and reused names. They had a meaning in the past and they are still using the names for something similar."

More Nutanix Cloud Infrastructure (NCI) cons

Pricing and Cost Advice

"The price is a bit high. It could be better, but the product is worth the cost."

"The price is a bit too high."

"Here in Brazil... it is very expensive. It's very hard for almost all companies to buy even the small version of this solution."

"The cost is expensive, but there is a chance to save money in the future."

"Initially HyperFlex was a little costly, it was higher, but Cisco wanted to get into our company, so they gave us a fair discount."

"Cisco HyperFlex HX-Series is expensive. It's a standard license, and we pay for it yearly. I think we pay about 700."

"It's roughly $30,000 per Hyperflex license, so that would be about $60,000 a year."

"There is a 30 percent additional premium that all the companies are charging for Cisco HyperFlex HX-Series because of the lack of chips and bottlenecks in the market. The cost of the solution is high right now."

More Cisco HyperFlex HX-Series [EOL] pricing and cost advice

"While cost may seem higher than your traditional 3-tier architecture, you need to look at the bigger picture. You're not just buying hardware here. You're buying a complete environment."

"It is not cheap, but if you look at the return on investment and the total cost of ownership, it is worth the price."

"The setup cost, pricing, and licensing are very competitive and TCO is very low compared to three-tier solutions."

"Nutanix Cloud Infrastructure is expensive."

"The price of the solution could improve. Nutanix has recently changed its pricing model from perpetual to subscription. They have identified there are challenges with the pricing model."

"Cost-wise, it is very good. It is like the hypervisor cost is not there. We only need to pay for the system and AOS licenses."

"This product is less expensive than some of the competing HCI solutions."

"They offer multiple tier licensing which means that lower level licensing will have less features."

More Nutanix Cloud Infrastructure (NCI) pricing and cost advice

See which vendors are best for you

Use our free recommendation engine to learn which HCI solutions are best for your needs.

See recommendations

880,844 professionals have used our research since 2012.

Comparison Review

it_user244362

Managing Consultant with 51-200 employees

Aug 30, 2015

Nutanix vs. VMware EVO:RAIL vs. FlexPod

Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…

Read full review

Answers from the Community

Netanya Carmi

Content Manager at PeerSpot

Aug 2, 2022

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

See 2 answers

Leah Fainchtein Buenavida

Tech Blogger

Oct 17, 2021

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

Read full answer

Steffen Hornung

Administrator at Neuberger Gebäudeautomation GmbH

Aug 2, 2022

With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.

Read full answer

Top Industries

By visitors reading reviews

Computer Software Company

12%

Manufacturing Company

Financial Services Firm

Construction Company

Computer Software Company

13%

Manufacturing Company

Government

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	17
Large Enterprise	57

By reviewers
Company Size	Count
Small Business	92
Midsize Enterprise	77
Large Enterprise	82

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...

See all answers

How does VxRail compare with Cisco HyperFlex HX Series?

VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...

See all answers

What makes Nutanix Cloud Infrastructure (NCI) worth using?

NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...

See all answers

Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?

NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...

See all answers

Do you think Nutanix Cloud Infrastructure (NCI) is a secure solution?

Nutanix Cloud Infrastructure is a very secure solution and ensures this through its Flow Network Security feature. The platform establishes a foundation through a Zero Trust strategy that is compat...

See all answers

Comparisons

HPE SimpliVity vs Cisco HyperFlex HX-Series [EOL]

Compared 15% of the time

Dell PowerFlex vs Cisco HyperFlex HX-Series [EOL]

Compared 12% of the time

Sangfor HCI - Hyper Converged Infrastructure vs Cisco HyperFlex HX-Series [EOL]

Compared 12% of the time

VxRail vs Cisco HyperFlex HX-Series [EOL]

Compared 11% of the time

HPE Alletra dHCI vs Cisco HyperFlex HX-Series [EOL]

Compared 10% of the time

More Cisco HyperFlex HX-Series [EOL] Competitors

VMware vSAN vs Nutanix Cloud Infrastructure (NCI)

Compared 8% of the time

VxRail vs Nutanix Cloud Infrastructure (NCI)

Compared 7% of the time

HPE SimpliVity vs Nutanix Cloud Infrastructure (NCI)

Compared 7% of the time

Sangfor HCI - Hyper Converged Infrastructure vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Azure Local vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

More Nutanix Cloud Infrastructure (NCI) Competitors

Product Reports

Buyer's Guide

Cisco HyperFlex HX-Series [EOL]

January 2026

Download Cisco HyperFlex HX-Series [EOL] product report

Buyer's Guide

Nutanix Cloud Infrastructure (NCI)

January 2026

Nutanix Cloud Infrastructure (NCI) report

Download Nutanix Cloud Infrastructure (NCI) product report

Also Known As

No data available

Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis

Overview

The Cisco HyperFlex HX Data Platform is a purpose-built, high-performance, scale-out file system with a wide array of enterprise-class data management services. The data platform’s innovations redefine distributed storage technology, giving you complete hyper-convergence with enterprise storage features:

Enterprise-class data management
Continuous data optimization
Securely encrypted storage
Dynamic data placement
Clusterwide parallel data distribution
Linear and incremental scaling
API-based data platform architecture
A simplified approach

Cisco

Nutanix Cloud Infrastructure delivers high performance and scalability with central management and one-click upgrades. It enhances data protection and reduces deployment complexities, perfect for businesses seeking efficient virtualization.

Nutanix Cloud Infrastructure offers a comprehensive platform integrating compute, storage, and network for optimal infrastructure management. It supports multiple hypervisors, offering flexibility, efficiency, and ease of use. With features like Prism for centralized management, organizations can manage resources effectively while benefiting from data protection enhancements such as deduplication and compression. Hyper-convergence enables seamless integration, reducing operational costs and increasing scalability. Though the pricing is high, and setup and administration can be complex, the ability to support hybrid cloud implementations and critical infrastructures like VDI and databases provides notable advantages.

What are the key features of Nutanix Cloud Infrastructure?

Prism for Centralized Management: Simplifies resource management with a single control interface.
High Performance: Offers efficient I/O operations to enhance processing efficiency.
Scalability: Easily adjusts to growing business needs with one-click upgrades.
Data Protection: Uses deduplication and compression for secure data handling.
Hyper-Convergence: Integrates compute, storage, and network to optimize infrastructure.
Multi-Hypervisor Support: Provides flexibility to choose preferred hypervisors.

What benefits should users look for in Nutanix Cloud Infrastructure?

Cost Effectiveness: Reduces operational costs through resource optimization.
Ease of Management: Centralized control enhances administrative efficiency.
Scalability: Grows seamlessly with business demand.
Data Protection: Increases security and reliability of data management.
Performance Improvement: Streamlines server provisioning and resource management.

Nutanix Cloud Infrastructure finds adoption across industries for virtualization, cloud services, and infrastructure consolidation. Organizations utilize it for hybrid clouds and virtual server hosting, supporting applications like databases and virtual desktop infrastructures. They report enhanced data protection, disaster recovery capabilities, and improved performance, facilitating effective resource management.

Nutanix

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest

St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.

Find out what your peers are saying about Dell Technologies, Broadcom, StarWind and others in HCI. Updated: December 2025.

DOWNLOAD NOW

880,844 professionals have used our research since 2012.

See our list of best HCI vendors.

We monitor all HCI reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.