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Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco HyperFlex HX-Series [...
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
90
Ranking in other categories
No ranking in other categories
Nutanix Cloud Infrastructur...
Average Rating
8.6
Reviews Sentiment
7.4
Number of Reviews
198
Ranking in other categories
Software Defined Storage (SDS) (5th), HCI (3rd), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)
 

Featured Reviews

Nuno Mendes - PeerSpot reviewer
High performance solution that makes it easy to efficiently manage VM resources
In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).
Andrea Beccia - PeerSpot reviewer
Offers satisfying data protection and workload movement features with exceptional stability
Nutanix Cloud Infrastructure can be used up to 100% of its capacity, but our company is presently using 80% of the solution's resources. Our company manufactures iron casting products in the metal industry, and Nutanix Cloud Infrastructure is also used. For virtualization purposes, Nutanix Acropolis is used as a full-stack solution. For the Windows virtual machines in our company's server, Nutanix Acropolis is utilized instead of solutions like VMware Hypervisor. One of the main reasons our company adopted Nutanix Cloud Infrastructure was its data protection features. The solution is also used in disaster recovery through the automatic snapshots feature on the local site. Next year, our organization will try to join clusters in the network using the solution. Network clustering will help our organization's team move workloads into the geographical cluster automatically. Nutanix Cloud Infrastructure is considered an ideal solution for disaster recovery where data protection remains embedded. The solution is capable of even capturing auto snapshots for remote sites. Next year, our company plans to test new features of Nutanix Cloud Infrastructure that will assist in automated workload movements on two sides at a distance of 60 kilometers. I would recommend others use the solution for its exceptional stability, performance, hardware compatibility, and overall flexibility. Nutanix Cloud Infrastructure allows the use of varying hardware for the same cluster. I would rate the solution a nine out of ten overall.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It is a hyper-converged solution which integrates with the network instead of the product."
"The scalability of the product is quite good overall - as long as you plan correctly from the outset."
"It saves space for data centers, which is good."
"It is a stable and scalable solution."
"The UCS, which is by far the best management tool there is on the market, regardless of vendor. It's the only tool I see that gives you the opportunity to size and scale all the assets and capacity you have in your data center, from a unified view."
"When we use it for VDI solutions, it is very easy to deploy and support."
"The integration between the storage and the server applications is the most valuable feature of this solution. It cuts down on the necessity to buy a secondary storage system.. It saves money in the long-run."
"Easily facilitates remote work opportunities with storage and compute resources."
"The most valuable feature would be the ease of deployment. That is the most significant feature for me because I've worked with multiple vendors and it's always been very complicated to install the software and get everything running."
"The solution is very stable. We haven't had any issues."
"Nutanix Acropolis AOS is stable. We didn't receive any concerns regarding any problems, The customers have no concerns about the reliability."
"It consolidates our servers, and improves our electricity consumption and cooling as well."
"The most valuable features are the RBAC, role-based access control, and the reporting. NCI also provides a single platform, a single pane with a dashboard, to manage the entire infrastructure. We have complete information about overall utilization, performance, and a forecast for our platform in that single pane."
"Single-click upgrades are the most valuable feature. In the sector in which we work, it is tough to have downtime and arrange firmware upgrades."
"The initial setup is straightforward."
"Technical support is okay."
 

Cons

"Maybe a better version is required to gather all of the information to allow HyperFlex to bring everything online more rapidly."
"The initial setup is very complex because there were some issues. It is not clear to how set up this solution."
"There is a VMware plugin for HyperFlex, which sometimes it hangs up in our environment, and doesn't function well."
"Some of our customers do not want to adopt the Cisco ACI solution. They want to manage Cisco HyperFlex by integrating it with their own management solution."
"The initial setup can be complex."
"The problem is that we always have to keep an eye out for new releases to make sure that the version we're running is up-to-date."
"It would have been nice if the product provided some cloud integrations."
"Does not support the stretch cluster, and the interface is not good."
"It would be fantastic if there was a built-in layer, in Nutanix, that acted like a cloud interface. So far, we need to integrate a cloud interface on top of Nutanix for billing the usage for specific customers' domains. It would be great if a cloud gateway was built-in, inside Nutanix."
"The process of migrating from old hardware to new could improve."
"One thing to keep in mind is that only experts can use it. It has to be in the proper hands, instead of going to XYZ people just for some cost savings. So lift-and-shift and migrations might be tricky, because it is not like a VMware."
"They should support more VM, which is not currently supported."
"An area for improvement would be the cyber security features."
"One disadvantage of Nutanix Acropolis AOS is it doesn't support external storage. Connecting external SAN storage to Nutanix, it's not supported."
"The self-service side of the product needs to be improved. We should be able to add two-factor authentication and more security layers to it."
"We could always use a performance upgrade, or simplified management."
 

Pricing and Cost Advice

"Cisco HyperFlex HX-Series is a bit pricier compared to other brands in the market...There is a need to make additional payments towards the maintenance and support of the solution."
"We are on an annual subscription and the price is fair."
"Here in Brazil... it is very expensive. It's very hard for almost all companies to buy even the small version of this solution."
"Initially HyperFlex was a little costly, it was higher, but Cisco wanted to get into our company, so they gave us a fair discount."
"The cost is expensive, but there is a chance to save money in the future."
"The pricing is a bit expensive."
"Comparable solutions with switches, storage, and services are cheaper than HyperFlex. It should be cheaper."
"When we negotiated with Cisco for the HyperFlex solution, they gave us a good price because they wanted to break into the market in Portugal for the first time. However, in general, I think it's a very expensive solution. It's a huge amount of money to acquire this kind of infrastructure."
"Nutanix Cloud Infrastructure’s pricing is very good and competitive."
"The price of the solution is high."
"The pricing of Nutanix is not cheap but there are options available."
"Our licensing fee on the total setup up was about R900 000."
"We renew our license on a yearly basis and have no costs in addition to the standard fee."
"Work close with your InfraTeam and discuss with Nutanix the best way to achieve sizing and price that are right for you."
"It's a cost-effective solution"
"I would rate the price seven out of ten with ten being the most expensive."
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Comparison Review

it_user244362 - PeerSpot reviewer
Aug 30, 2015
Nutanix vs. VMware EVO:RAIL vs. FlexPod
Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…
 

Answers from the Community

NC
Aug 2, 2022
Aug 2, 2022
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrat...
See 2 answers
Oct 17, 2021
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.
Steffen Hornung - PeerSpot reviewer
Aug 2, 2022
With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.
 

Top Industries

By visitors reading reviews
Computer Software Company
23%
Financial Services Firm
9%
Government
8%
Manufacturing Company
7%
Educational Organization
27%
Computer Software Company
14%
Financial Services Firm
7%
Manufacturing Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...
How does VxRail compare with Cisco HyperFlex HX Series?
VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...
What is the biggest difference between Nutanix Acropolis and VMware vSphere?
We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...
Which would you choose - Nutanix Acropolis AOS or VMware vSAN?
We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...
What makes Nutanix Cloud Infrastructure (NCI) worth using?
NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...
 

Also Known As

No data available
Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis
 

Overview

 

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest
St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.
Find out what your peers are saying about Dell Technologies, VMware, Nutanix and others in HCI. Updated: May 2025.
860,168 professionals have used our research since 2012.