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Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco HyperFlex HX-Series [...
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
90
Ranking in other categories
No ranking in other categories
Nutanix Cloud Infrastructur...
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
199
Ranking in other categories
Software Defined Storage (SDS) (6th), HCI (5th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)
 

Featured Reviews

Nuno Mendes - PeerSpot reviewer
IT Manager - Resp.Department at Parvalorem
High performance solution that makes it easy to efficiently manage VM resources
In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).
OB
Head Systems Administration/Security at Nigeria Inter-Bank Settlement System PLC
Infrastructure efficiency has improved significantly with quick server provisioning, though physical to virtual migrations need a streamlined in-house tool
From my experience with Nutanix Cloud Infrastructure (NCI), there is one area that needs improvement. When moving a critical infrastructure from a physical machine to Nutanix Cloud Infrastructure (NCI), we currently have to use a third-party tool to convert the physical machine to a VM. We have to use VMware converter to perform this conversion before moving it to Nutanix Cloud Infrastructure (NCI). I would suggest that Nutanix Cloud Infrastructure (NCI) should develop their own P2V (physical to VM) tools instead of requiring users to rely on third-party solutions.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The price of the solution is good, especially when it comes to complex network solutions, such as UCS and Connect."
"The most valuable feature is that it is something small that can be more easily deployed than a full data center set of servers."
"It saves space for data centers, which is good."
"It is a hyper-converged solution which integrates with the network instead of the product."
"I love the Cisco design, the visual interface to manage and use the platform."
"Most of our users are Cisco customers, so it fits in within the suites we use. Primarily for me, as a solution architect, it's the technology and architecture that is the most valuable. I know from my technical colleagues that it's easy to use and for the customer, the up-time is the most valuable asset. It's running, has low failure, and so on which is why we use it."
"The UCS, which is by far the best management tool there is on the market, regardless of vendor. It's the only tool I see that gives you the opportunity to size and scale all the assets and capacity you have in your data center, from a unified view."
"The technical support has been very good for this solution."
"One of the most valuable features of Nutanix is that it's easy to use. I love this solution—it's easy to maintain and update, and I think it's almost perfect."
"Scaling is very easy and no limitations are set."
"It gives us a single dashboard to control multiple sites and multiple zones. It helps to do things on a single platform and data sharing is quite easy. The network and the security are easy to manage."
"The snapshots, cloning, and replication are all effective in helping to reduce downtime. It can replicate cluster data for disaster recovery and it provides high availability in case a node or a disk fails."
"Most beneficial feature is simplicity, ease of use."
"We really love the Lifecycle manager and one-click upgrades."
"The ease of deployment is very good."
"Karbon is a must-have as it drastically simplifies the deployment of Kubernetes."
 

Cons

"Cisco's technical support originally was outstanding, but it has declined over the last 12 months. I've heard they're trying to do better, but I haven't been overly impressed with their support recently for HyperFlex."
"It needs improvements in terms of I/O. Sometimes I have felt it is slightly slow while we are trying to provision VMs or access VMs."
"Cisco is a bit more challenging in terms of deployment. The admin must be knowledgeable in order to complete the task. Without that knowledge, it will be difficult to complete."
"With the cache disk fails in Cisco, the whole node fails, and the workload goes down."
"They can't get a POC to work because there are big latencies between the two sites we have. Even though we have a private fiber connection and everything else works well, they can't get the two products to talk to each other. They are not able to build it up. It looks like it's a firmware issue. They said it isn't but now it's looking like it is. I hope we can sort it out."
"Unlike other options, you need to pay a subscription to Cisco yearly instead of paying for the hardware outright, which makes it more expensive in the long run."
"HyperFlex could be improved by reducing the minimum number of nodes supported from three to two."
"I would like it to be easier to manage the server, create VMs, and manage the VMs on the client."
"I believe that improvements could be made in regards to the DR in addition to deduplication and integration with others platforms. They also do not offer opportunities for network virtualization so it would be nice to see that in the future."
"In terms of the IT different categories, I would like for the governing sections to be able to use it in the IT department. If they can have something like a one view management portal or software similar to VMware that would be an added value."
"I would enjoy an advanced mode where experienced users can leverage their knowledge to do advanced things currently only allowed using the command line tools on the CVM."
"In the future, I would like to see integration with external storage using the fiber channel"
"It would be great if they could improve the GUI features."
"Native File-Services are under heavy development and Container Services just came out."
"When moving a critical infrastructure from a physical machine to Nutanix Cloud Infrastructure (NCI), we currently have to use a third-party tool to convert the physical machine to a VM."
"An area for improvement would be the cyber security features."
 

Pricing and Cost Advice

"Initially HyperFlex was a little costly, it was higher, but Cisco wanted to get into our company, so they gave us a fair discount."
"When we negotiated with Cisco for the HyperFlex solution, they gave us a good price because they wanted to break into the market in Portugal for the first time. However, in general, I think it's a very expensive solution. It's a huge amount of money to acquire this kind of infrastructure."
"The product could be cheaper."
"Cisco HyperFlex HX-Series is a bit pricier compared to other brands in the market...There is a need to make additional payments towards the maintenance and support of the solution."
"There is a recurring cost for the VMware license and the HyperFlex licenses."
"Comparable solutions with switches, storage, and services are cheaper than HyperFlex. It should be cheaper."
"The price is a bit too high."
"Our licensing costs are large, but it is combined between all of the Cisco products that we have."
"The solution is quite expensive."
"I don't feel that I am receiving the performance which I am paying for."
"Nutanix Cloud Infrastructure could be cheaper. It's costly to upgrade the solution. There are no additional costs aside from the license."
"We just have a support license for Nutanix."
"NCI is quite expensive compared to other products. It would help us if Nutanix considered affordability when releasing new products. We have an annual license and are considering extending it for another year."
"I would rate the price seven out of ten with ten being the most expensive."
"It is less expensive than the VMware alternative."
"Its price is fine. I can't really complain about that."
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Comparison Review

it_user244362 - PeerSpot reviewer
Managing Consultant with 51-200 employees
Aug 30, 2015
Nutanix vs. VMware EVO:RAIL vs. FlexPod
Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…
 

Answers from the Community

NC
Content Manager at PeerSpot
Aug 2, 2022
Aug 2, 2022
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrat...
See 2 answers
Oct 17, 2021
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.
Steffen Hornung - PeerSpot reviewer
Administrator at Neuberger Gebäudeautomation GmbH
Aug 2, 2022
With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.
 

Top Industries

By visitors reading reviews
Computer Software Company
14%
Manufacturing Company
8%
Financial Services Firm
8%
Construction Company
7%
Computer Software Company
15%
Manufacturing Company
9%
Government
8%
Financial Services Firm
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise17
Large Enterprise57
By reviewers
Company SizeCount
Small Business91
Midsize Enterprise77
Large Enterprise82
 

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?
Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...
How does VxRail compare with Cisco HyperFlex HX Series?
VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...
What makes Nutanix Cloud Infrastructure (NCI) worth using?
NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...
Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?
NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...
Do you think Nutanix Cloud Infrastructure (NCI) is a secure solution?
Nutanix Cloud Infrastructure is a very secure solution and ensures this through its Flow Network Security feature. The platform establishes a foundation through a Zero Trust strategy that is compat...
 

Also Known As

No data available
Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis
 

Overview

 

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest
St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.
Find out what your peers are saying about Dell Technologies, Broadcom, StarWind and others in HCI. Updated: December 2025.
879,259 professionals have used our research since 2012.