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ThreatLocker Zero Trust Platform vs Uptycs comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 17, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
ThreatLocker Zero Trust Pla...
Ranking in Endpoint Protection Platform (EPP)
5th
Average Rating
9.2
Reviews Sentiment
7.1
Number of Reviews
83
Ranking in other categories
Network Access Control (NAC) (3rd), Advanced Threat Protection (ATP) (5th), Application Control (1st), ZTNA as a Service (5th), ZTNA (6th), Ransomware Protection (1st)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
44th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (36th), Endpoint Detection and Response (EDR) (48th), Cloud Workload Protection Platforms (CWPP) (23rd), Extended Detection and Response (XDR) (40th), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of September 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.8% compared to the previous year. The mindshare of ThreatLocker Zero Trust Platform is 1.3%, up from 0.9% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.8%
ThreatLocker Zero Trust Platform1.3%
Uptycs0.5%
Other94.4%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Santo Joy - PeerSpot reviewer
Head Of Cyber Security at a outsourcing company with 201-500 employees
Security controls have been strengthened with granular application, ringfencing, and access policies
The features of ThreatLocker Zero Trust Endpoint Protection Platform that I like the most are the Ringfencing, elevation control, storage control, and application whitelisting functionality. For examples of how these features benefit my company, we were looking for a solution across various vendors to actually implement application whitelisting controls. ThreatLocker's agent, which is very lightweight and does not use much CPU or RAM, helped us achieve that solution. Ringfencing was an add-on that ticked off a lot of Australian framework security controls, which is the reason we chose it. My impression of the allowlisting feature in terms of managing which software, scripts, and libraries run on my devices is that ThreatLocker's community page has a lot of information around this, which is very helpful. Not only that, the Cyber Hero support that ThreatLocker provides gives us insights and best practices, helping us achieve that solution and guiding us to the right platform. The impact of Ringfencing on controlling the behavior of approved applications has been a big winner for us because it is something that many other platforms do not provide as a functionality. Having that allowed us to identify what applications talk to each other, which is something that many other platforms do not do. The network control feature impacts my ability to manage network traffic across my endpoints and servers. We have not used this widely across all our partners, but wherever required, we use it. It has been an easy solution for those customers to get that control implemented. The elevation feature's role in facilitating just-in-time administrative access for approved applications shows that elevation control helps in many use cases involving remote control platforms, door usage, and security system platforms that require local admins. There are many solutions that provide this functionality, but the licensing cost seems to be expensive, and it also adds another solution into the mix. Rather than doing that, we try to use ThreatLocker Zero Trust Endpoint Protection Platform to achieve that control. Regarding the storage control feature, I have used it. The primary function is USB blocking, which is very widely adopted, and also just locking down and allowing certain users to access certain file locations helps us there. When it comes to enforcing policy-driven access over various storage devices, it depends on the business risk adapted by the companies that we support, but generally the use case is USB and external storage devices where companies know that is a risk, but they do not have appropriate solutions. There are EDR platforms that claim to do this, but ThreatLocker Zero Trust Endpoint Protection Platform does it at an advanced level. My assessment of the efficiency of the real-time threat intelligence and category controls employed by Web Control in blocking malicious and non-compliant sites leads me to think that Web Control is another functionality within ThreatLocker Zero Trust Endpoint Protection Platform that is an add-on on top of the current set. That is another solution that we use based on what is required for the company, but again, that is not widely adapted yet for our partners.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Once you become familiar with it, Cortex XDR by Palo Alto Networks is a more powerful tool and I would say that I prefer it over MDE because it is a stronger tool for me."
"The integrations are out-of-the-box, as are the playbooks."
"The normal protection was really effective, and we detected situations that if we didn't have Cortex XDR by Palo Alto Networks, it's highly likely that we would have been affected, but it protected the infrastructure."
"We think that this product will help us grow, as it meets our needs currently and we can grow with it over time."
"From the Palo Alto side, whatever they buy, they integrate that really well into their integration suite, and that makes a massive difference."
"Cortex XDR lets us manage several clients from the same console, and its endpoint defense is more advanced than traditional antivirus."
"Cortex XDR is a very capable solution for protecting large networks and a lot of endpoints. It's very useful because the automation is very high, and if you combine it with the features on Palo Alto firewalls, it provides very strong protection."
"Palo Alto is the core of the security infrastructure in the environment."
"The great thing is that if you get a malicious email and you try to run something, ThreatLocker is not going to let it do anything. It is not going to let anything infect your network."
"The sandbox functionality is fantastic."
"As for the customer service and technical support of ThreatLocker Zero Trust Endpoint Protection Platform, I would rate them from one to 10 as a 20."
"Zero-Touch is the future, and ThreatLocker Zero Trust Endpoint Protection Platform is the easiest way to accomplish that."
"The application management on any workstation with the solution is valuable. I find it valuable that it indicates whether the software is part of our pre-approved list, adding a nice layer of protection. It works great because people cannot just install or download any app from the web."
"With ThreatLocker, we don't have shadow IT, and it has reduced ransomware."
"The most valuable feature is its learning capability."
"Ringfencing is a valuable feature."
"They have multiple great features."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
 

Cons

"It is an enterprise-level solution. Its price could be less expensive."
"In some cases, there are too many options for me, and it is a bit too hard to find some settings which I really need to implement."
"Whenever the tool releases a new version when deploying the product across the organization, I feel like there are some disturbances in the CPU usage after upgrading the tool to the latest version."
"When it comes to malware files, it should be a little quick because, at times, it would give a wrong result in the sense of what it might be on malware, even if it still might be a normal one."
"If Palo Alto reduces the pricing slightly for their products, it would make them more scalable in markets such as India and globally for cybersecurity."
"It automatically detects security issues. It should be able to protect our network devices while operating autonomously."
"It is not easy to sell Cortex XDR, not because it isn't a good tool. Its marketing needs to be improved."
"Previously, the endpoint would leave the environment, not being on our VPN, essentially unable to interact with the server to upload files. It was unable to retrieve new file verdicts. It was using a thing called "local analysis" to determine if something was a malicious file or not. There was no dynamic analysis."
"The reporting could be improved."
"It's very annoying to uninstall. You have to go into the online control panel and disable tampering for a device before it'll let you uninstall it without complaining really loudly."
"If I have to say what they can improve, one area would be making policy tuning and onboarding simpler for large enterprise environments."
"I'm not sure if I'm using it wrong; however, I find that I have to babysit it too much."
"The user experience could be improved. Most complaints we get are based on users wanting certain functionality."
"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."
"From one to ten, I would rate the solution overall as a nine out of ten just because the initial setup was a little confusing."
"Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"The solution is expensive. It's pricing is on a yearly-basis."
"This is an expensive solution."
"It has reasonable pricing for the use cases it provides to the company."
"The pricing is a little high. It is per user per year."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"The price is on the higher side, but it's okay."
"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"I find ThreatLocker's pricing to be reasonable for the services it provides."
"We have not had any real issues with the pricing. As they have added more features, due to the way our contracts are structured with our customers, we have had to hold off on adopting the new features because they do add costs."
"The pricing is reasonable and normal. I do not have any problems with the cost."
"The pricing works fine for me. It's very reasonably priced."
"I can't complain. Cheaper would always be nice, but I think it's reasonable compared to other software in the cybersecurity market."
"The price is very reasonable, and we have been able to integrate ThreatLocker with all of our clients."
"ThreatLocker's pricing seems justifiable."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
Information not available
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Manufacturing Company
9%
Manufacturing Company
11%
Financial Services Firm
11%
Computer Software Company
10%
Outsourcing Company
9%
Computer Software Company
13%
Construction Company
11%
Comms Service Provider
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business58
Midsize Enterprise14
Large Enterprise15
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
I am not sure about operational or cost expenses because we have not really experienced that.
What needs improvement with ThreatLocker Allowlisting?
When it comes to ThreatLocker Zero Trust Platform's policy making, it is very granular, but the moment you zoom out, ...
What is your primary use case for ThreatLocker Allowlisting?
ThreatLocker Zero Trust Platform's main use case for us was data storage access control.We used ThreatLocker Zero Tru...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Protect, Allowlisting, Network Control, Ringfencing
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Information Not Available
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about ThreatLocker Zero Trust Platform vs. Uptycs and other solutions. Updated: September 2026.
914,394 professionals have used our research since 2012.