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Microsoft Defender for Endpoint vs Uptycs comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Ranking in Endpoint Detection and Response (EDR)
6th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
113
Ranking in other categories
Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
1st
Ranking in Endpoint Detection and Response (EDR)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (5th), Anti-Malware Tools (1st), Microsoft Security Suite (3rd)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
44th
Ranking in Endpoint Detection and Response (EDR)
51st
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (37th), Cloud Workload Protection Platforms (CWPP) (23rd), Extended Detection and Response (XDR) (39th), Cloud Security Posture Management (CSPM) (33rd), Cloud-Native Application Protection Platforms (CNAPP) (22nd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of July 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.7% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.8%, down from 10.5% compared to the previous year. The mindshare of Uptycs is 0.4%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.8%
Cortex XDR by Palo Alto Networks3.8%
Uptycs0.4%
Other89.0%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The stability is pretty good except for one or two cases, and based on the performance, it's been okay with pretty high performance, no bugs or glitches, and it doesn't crash or freeze."
"The initial setup is easy."
"The policy configuration is great, the granularity of policies that are available is very helpful, it is straightforward to set up, and it has pretty much everything we need and works well within the Palo Alto ecosystem."
"After installing this solution, it identified, blocked, and provided the complete attack chain, which was very helpful."
"The product has an intuitive dashboard."
"We have a complete overview of all our PCs and it's very easy to handle and to use the interface. It has a lot of benefits for us."
"The product is very good, it has caught a lot of exploits that most products would not."
"I recommend this solution to others because it is easy to manage, reliable, and overall good to use."
"For the end user it's good to know that everything is safe and well protected."
"In my opinion, the most valuable aspects are the reporting analytics and integration with Sentinel. Defender does an excellent job of correlating the different entities that comprise threat analysis, analytics data, and log analytics. It helps to piece together investigations into any exploit or malicious activity within a specific tenant. AI and analytics tools are probably the most valuable components."
"We had some problem and, after four hours, we had new signatures for the environment by our customers for more than a thousand clients so that we can protect and improve the new setup."
"We used CrowdStrike but we switched to Microsoft because of the price."
"Overall, I recommend Microsoft Defender for Endpoint due to its features and capabilities, which cover more loopholes than other EDR solutions."
"It's a very complete application. I have all the controls in one site. I can track emails, attacks, and threats, and I can research information. I really like this configuration because I have all the information in place."
"We use Microsoft Defender for the antivirus."
"The price of Microsoft Defender for Endpoint is reasonable, as other solutions, such as ClowdStrike, are more expensive."
"They have multiple great features."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
 

Cons

"The onboarding process could be better."
"There's room for improvement with Mac device installations, which can be challenging."
"It's very time-consuming to log support issues and the people that answer the tickets aren't very knowledgeable."
"The negative aspect I see is the economic model used by Palo Alto."
"In reporting they should have a customizable dashboard due to the fact that C-level people don't like reporting to the IT department. They prefer to have a real-time dashboard. That kind of dashboard needs to have various customizations."
"The playbooks could be improved to include more functionalities or actions."
"The solution could improve by providing better integration with their own products and others."
"One thing that was missing was the integration part. Currently, they don't have out-of-box integration with IBM QRadar, or if they have the integration, the integration doesn't work well."
"There is a need for improvement in reducing false positives."
"Notifications are always popping up — I hate that."
"Right now, there's a portal for Azure, portals for Microsoft Office, and portals for endpoints. It would be good to have only one portal and integrate everything."
"It's a good product but it is limited in some cases."
"I am not sure if I will be using this product in the future because of the price."
"Lowering the price would be an improvement."
"At times, the other antivirus products are now doing AI, in terms of understanding the behavior of the system and determining when there's an anomaly. This is something that Defender can improve on."
"Microsoft Defender for Endpoint does not offer default templates for alerts, requiring us to configure everything ourselves to avoid numerous false positives."
"We end up facing a lot of issues after upgrades."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
 

Pricing and Cost Advice

"The pricing is a little bit on the expensive side."
"The pricing is okay, although direct support can be expensive."
"Every customer has to pay for a license because it doesn't work with what you get from a managed services provider."
"It is cost-effective compared to similar solutions. It fits for the small businesses through to the big businesses."
"The cost of Cortex XDR by Palo Alto Networks is $55 to $90 USD per endpoint per month."
"The price was fine."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"Cortex XDR's pricing is ok."
"The cost is high for E5 licenses, but if we go with the E3 license, most of the features are not covered."
"Compared to ESET, the pricing for Microsoft Defender for Endpoint is on the higher side."
"AV solutions are pretty expensive because they are necessary, not just for protection, but many businesses need them to comply with regulatory bodies and receive accreditation. We recently purchased an E5 license, which gives us access to the entire Microsoft suite. I would say the pricing is competitive; most tools of this kind are similarly priced. There are minor differences between the competitors, but they aren't spectacularly different. Defender for Endpoint makes sense because all our solutions are in the same place, paid for with a single license. The subscription price is around £50 per user per month, though it may have increased slightly."
"Pricing can always be lower."
"Because Microsoft Defender comes as an add-on, it can be a bit expensive if you're trying to buying it separately. Another option is to upgrade, but the enterprise licenses for Microsoft can also be quite a bit pricey. Overall, the cost of Microsoft Defender compared to that of other endpoint detection solutions is slightly higher."
"Licensing models of Microsoft are renowned for being complex. We just purchased the whole E5 stack. With E5 licenses for users, we get access to a bunch of features that are not just related to security. I would rate them a three out of five in terms of pricing."
"We went for Microsoft Defender once we were informed that it would be part of our Office 365 package. So, we combined the licensing for the OS with Office 365. Yeah. We thought it was a good bargain."
"The solution is free with Windows."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Manufacturing Company
10%
Financial Services Firm
10%
Computer Software Company
9%
Comms Service Provider
8%
Financial Services Firm
19%
Construction Company
13%
Insurance Company
6%
Transportation Company
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise21
Large Enterprise52
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Petrofrac, Metro CSG, Christus Health
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Uptycs and other solutions. Updated: June 2026.
902,988 professionals have used our research since 2012.