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Microsoft Defender for Endpoint vs Uptycs comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
115
Ranking in other categories
Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
1st
Ranking in Endpoint Detection and Response (EDR)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (5th), Anti-Malware Tools (1st), Microsoft Security Suite (3rd)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
44th
Ranking in Endpoint Detection and Response (EDR)
50th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (36th), Cloud Workload Protection Platforms (CWPP) (23rd), Extended Detection and Response (XDR) (39th), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of August 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.9%, up from 3.7% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.7%, down from 10.2% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.7%
Cortex XDR by Palo Alto Networks3.9%
Uptycs0.5%
Other88.9%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The tool's use cases are relevant to security."
"The most valuable features are incident creation, policy-based protection, IP whitelisting, and device encryption. These are beneficial for endpoint and server security."
"From the Palo Alto side, whatever they buy, they integrate that really well into their integration suite, and that makes a massive difference."
"I generally believe that Cortex XDR by Palo Alto Networks is probably the best in the market right now."
"Cortex XDR by Palo Alto Networks has changed the way my security team detects, investigates, and responds to threats, as we are able to see the files, unwanted files, unsecured files, and unauthorized files, so we are quarantining them."
"This software helps us understand any issues that may arise when someone is not at work."
"The solution's most valuable feature is the user interface."
"What I like about Cortex XDR by Palo Alto Networks is that it is a comprehensive solution that contains everything the organization may need when using endpoints."
"Defender's analytics are much better than CrowdStrike's."
"It works well with different solutions from Microsoft."
"I like the simplicity of the portal and the integration with Microsoft Intune. Microsoft Defender for Endpoint is easy to use and implement."
"We have very good visibility on our endpoints. The level of information it throws back is helpful."
"Microsoft's technical support is fantastic."
"It is a straightforward setup."
"The initial setup is not difficult or complex; it's very simple and straightforward."
"This solution absolutely eliminated the need to look at multiple dashboards because we have one XDR."
"They have multiple great features."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
 

Cons

"It is not easy to sell Cortex XDR, not because it isn't a good tool. Its marketing needs to be improved."
"The solution should enhance the ADR and reporting."
"I have seen lagging with Cortex XDR by Palo Alto Networks. There was one time when we faced a threat actor trying to gain access to our system. When our team utilized the tool, we were all on the same dashboard and we faced a lag issue at that time of around five minutes, which was quite significant."
"It is not a suitable solution if you are looking for a single product with multiple features such as DLP, encryption, rollback, etc."
"The solution can never really be an on-premises solution based simply on the way it is set up. It needs metadata to run and improve. Having an on-premises solution would cut it off from making improvements."
"If Palo Alto reduces the pricing slightly for their products, it would make them more scalable in markets such as India and globally for cybersecurity."
"For Cortex XDR by Palo Alto Networks, if I had to point out improvements, I would say the UI is still somewhat difficult for beginners."
"Whenever the tool releases a new version when deploying the product across the organization, I feel like there are some disturbances in the CPU usage after upgrading the tool to the latest version."
"The solution can be more user-friendly."
"This solution needs to move beyond relying on virus definitions alone and protect the system using behavioral analysis of the processes that are running."
"The solution could be even more secure and provide an even higher level of security."
"Sometimes it is a little lacking, but for the most part, they are able to provide exactly what I need."
"Defender by itself is not a solution."
"The UI for Microsoft Defender for Endpoint needs to be better."
"Initially, I experienced performance issues that hampered our servers. However, after setting appropriate exclusions, everything seemed to work fine."
"They're in the process of pulling more things together. They can continue with the integrations and provide a better way of seeing the impact of security changes, especially on the endpoint side. Before we actually flip the switch, we should be able to see the impact of security changes on the business or business applications. It would prevent breaking any business applications."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"It is present, but when compared to other competitive products, I would say it is not less expensive; however, when all of the other added values are considered, the price is reasonable."
"It has a yearly renewal."
"The pricing is a little high. It is per user per year."
"It's about $55 per license on a yearly basis."
"The solution is expensive. It's pricing is on a yearly-basis."
"Compared to CrowdStrike, Cortex XDR is an expensive solution."
"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"Microsoft Defender for Endpoint comes with Windows 10, and it's free. But for you to be able to manage it in the cloud and use the console, you need to have either an Office 365 E5 subscription or a Microsoft M365 subscription. You need to buy an extra license."
"Even if you are not registered as a not-for-profit, the offering that they have is definitely worth consideration. This is in the sense that the E5 stack just gives you so many benefits. You get your entire productivity suite through Microsoft 365 apps. You get all your security and identity protection. You get the Defender for Endpoint and Defender for Identity. You get the cloud access security broker as well. You get Azure Active Directory Premium P2, which gives you so many good things that you can configure and deploy. You don't have to configure them on day one, but you have access to so many different tools that will protect your data, security, endpoints, and identities that you could build out a security strategy 18 months long, and slowly work your way through it, based on what you have available to you through your license."
"The solution is an open source version and was free with a paid version of Windows 10."
"There is an annual license required."
"Its price at the moment is very good because you get a lot of value for your money, especially with the subscriptions. If you have the E1, E3, or E5 enterprise subscription, you pay per month per user, and you get almost an infinite number of solutions. If you compare the price to the number of solutions that you get, it is a very good deal."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"For me, the pricing is very good, but for management it's very expensive. Other solutions are less expensive. But when I present all the information and all the reports they say, "Well, it's expensive, but the cost-benefit is very good.""
"We went for Microsoft Defender once we were informed that it would be part of our Office 365 package. So, we combined the licensing for the OS with Office 365. Yeah. We thought it was a good bargain."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Comms Service Provider
10%
Financial Services Firm
10%
Manufacturing Company
10%
Manufacturing Company
10%
Financial Services Firm
9%
Computer Software Company
8%
Comms Service Provider
8%
Computer Software Company
14%
Construction Company
13%
Financial Services Firm
12%
Outsourcing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise21
Large Enterprise54
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Petrofrac, Metro CSG, Christus Health
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Uptycs and other solutions. Updated: July 2026.
909,725 professionals have used our research since 2012.