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Microsoft Defender for Endpoint vs Uptycs comparison

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Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Extended Detection and Response (XDR) (3rd), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
2nd
Ranking in Endpoint Detection and Response (EDR)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (4th), Anti-Malware Tools (1st), Microsoft Security Suite (3rd)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
43rd
Ranking in Endpoint Detection and Response (EDR)
47th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (36th), Cloud Workload Protection Platforms (CWPP) (22nd), Extended Detection and Response (XDR) (42nd), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of October 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.7% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.5%, down from 9.9% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.5%
Cortex XDR by Palo Alto Networks3.8%
Uptycs0.5%
Other89.2%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cortex XDR by Palo Alto Networks has accelerated the response time for my security team, so we have been able to resolve issues faster than usual."
"One of the things that I enjoy the most is using policy extensions. It's like having host firewalls to control USB connections. I think it's a wonderful tool to restrict use when connecting to our computers. Another important tool is Home Insights. That is an add-on to the Cortex solution. I like that because we can see all the vulnerabilities in the environment and control what assets are connected to our network."
"From a single pane of glass, you can easily manage all of your endpoints."
"I can highlight that we have not faced any security incidents with Cortex XDR by Palo Alto Networks, and even though our environment is quite dynamic, we have not faced any security incident with Cortex XDR by Palo Alto Networks until now."
"Stability-wise, it is good; I did not hear about any issues in terms of stability, and Cortex XDR by Palo Alto Networks can be trusted completely."
"The protection offered by this product is good, as is the endpoint reporting."
"The main benefit of using Cortex XDR by Palo Alto Networks while employing Palo Alto Firewall at the internet edge is that it improves security on our endpoint devices, integrating seamlessly with Palo Alto Firewalls to deliver comprehensive network, analyst, and security details all in a single dashboard, which allows us to manage everything from our network devices."
"The solution allows us to gain remote access without the user's knowledge and take the necessary actions on the device."
"The whole bundle of the product, which is similar to other Microsoft products, is valuable. Ten years ago, you had third-party stuff for different things. You had one solution for email archiving and another third-party one for something else. Nowadays, Microsoft Office covers all the stuff that was formerly covered by third-party solutions. It is the same with antivirus. The functionality is just basic. You have the scanning, and then you also have a kind of cloud-based protection and reporting about your environment. With Microsoft Security Center, you have a complete overview of your environment. You know the software inventory, and you have security recommendations. You can not only see that the antivirus is up to date; you can also see where are the vulnerabilities in your system. Microsoft Security Center tells you where you have old, deprecated software and what kind of CVEs are addressed. It's really cool stuff."
"For companies that are Microsoft shops, I would recommend the product."
"The most valuable aspect is information, specifically the automatic investigation of packages."
"Its simplicity is the most valuable. It also has very good integration. We like it."
"Defender works in the background monitoring the traffic for viruses."
"The most valuable feature is its ability to effectively detect threats. It has the EDR feature, endpoint detection and response, and that is very good."
"For the most of it, it seems like Defender is well truly up there with the other best players in the market."
"You have endpoint security to keep your devices safe. That's the feature that we're interested in."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
"They have multiple great features."
 

Cons

"If Palo Alto reduces the pricing slightly for their products, it would make them more scalable in markets such as India and globally for cybersecurity."
"Currently, we are monitoring all USB drives and ports but we would like to improve our device control capabilities."
"In the next release, I would like to see more UI improvements. Their UI is a bit basic. When we are speaking about Palo Alto Networks they are the big company, so they can improve the UI a little bit. The UI, the reports, the log system can all be improved."
"We have found that there are times Cortex XDR by Palo Alto Networks does not detect some of the viruses, we have to use another protection solution called Kaspersky."
"A better pricing plan would make this product more competitive."
"Dashboards do not allow everyone to see what's happening."
"The negative aspect I see is the economic model used by Palo Alto."
"There's room for improvement with Mac device installations, which can be challenging."
"The user interface could use some improvement."
"A challenge is that it is not a multi-tenant solution. Microsoft's tenant is a licensed tenant. I'm an MSSP. So, I have multiple customers. In Microsoft's world, that means that I can't just buy an E5 license and give that out to all my customers. That won't work because all of the customer data resides within a single tenant in Microsoft's world. Other products—such as SentinelOne, Palo Alto Cortex, CrowdStrike, et cetera—are multi-tenant. So, I can have it at the top of the pyramid for my analyst to look into it and see all the customers, but each customer's data is separate. If the customer wants to look at what we see, they would only see their data, whereas in the Microsoft world, if I've got multiple customers connected to the same Microsoft tenant, they would see everybody else's data, which is a privacy problem in Europe. It is not possible to share the data, and it is a breach of privacy."
"Microsoft Defender in the basic form is not very useful for managing the security environment. The free version is not capable of covering the needs of centralized management, EDR, and behavioral analysis. If you don't have the commercial version, you can't have centralized management and set up the policies and other things. Each client is a standalone installation, which is not useful for security in an enterprise model."
"Their support is okay. We get support through Insight, which is also our CSP."
"It's not quite a mature solution just yet. It needs more time to grow and develop."
"Its interface can be improved a little bit. We would like to have some sort of centralization. It should have something like a central server that is managing all the other clients. There are solutions from Kaspersky or ESET NOD32 that are really doing this kind of thing currently. We would like to see something similar from Microsoft."
"Sometimes, there are different skews. In a basic skew, they should have basic log analysis without the need to integrate with any third-party or SIEM solutions, like Sentinel. This would make it so much easier for users who don't have log collection or log analysis."
"Its detection is not as quick. There should also be more frequent updates."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"The price of the solution is high for the license and in general."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"I don't have any issues with the pricing. We are satisfied with the price."
"The pricing is a little high. It is per user per year."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"Every customer has to pay for a license because it doesn't work with what you get from a managed services provider."
"Traps pays for itself within the first 16 months of a three-year subscription. This is attributed to OPEX savings, as security teams spent less time trying to identify and isolate malware for analysis as a result of a reduction in malware incidents, false positives, and breach avoidance."
"The solution is expensive. It's pricing is on a yearly-basis."
"Its price at the moment is very good because you get a lot of value for your money, especially with the subscriptions. If you have the E1, E3, or E5 enterprise subscription, you pay per month per user, and you get almost an infinite number of solutions. If you compare the price to the number of solutions that you get, it is a very good deal."
"Pricing can always be lower."
"Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs."
"For most people, the price of the license is not something that they have to worry about."
"Licenses depend upon what you are looking for and what kind of security do you want to implement. There are costs in addition to the standard licensing fees. When we used to buy Symantec, we used to spend on 100 licenses. We used to spend approximately $2,700 for those many licenses, and they came in packs. To add one more license, I had to buy a pack with a minimum of 10 licenses. I had to spend on nine extra licenses because I can't get a single license, whereas when we go for Microsoft, we can get as many licenses as we want. If I have 100 users today, and tomorrow, I have 90 users, I can release my 10 licenses next month. With any other software vendor, you buy licenses for one year, and you have to stick with that. If today you have 100 licenses, and tomorrow, you have 50, you have already paid for one year's license. You can't go back and tell them that I don't require these 50 licenses because I have lost my 50 users, but with Microsoft Defender, licensing is on a monthly basis. It gives you both options. You can go yearly and save on it, or you can go monthly. You will, again, save on it. It is very fair everywhere."
"You need a license to use this solution."
"Because Microsoft Defender comes as an add-on, it can be a bit expensive if you're trying to buying it separately. Another option is to upgrade, but the enterprise licenses for Microsoft can also be quite a bit pricey. Overall, the cost of Microsoft Defender compared to that of other endpoint detection solutions is slightly higher."
"The nice thing about Defender and Sentinel is that the cost is based on the data logs that you ingest from the Defender endpoints and data connectors. I don't have to buy a 25- or 50- or 1,000-user or enterprise license. I can buy one license at a time."
Information not available
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Manufacturing Company
10%
Manufacturing Company
10%
Financial Services Firm
9%
Comms Service Provider
8%
Computer Software Company
8%
Computer Software Company
13%
Comms Service Provider
11%
Construction Company
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise97
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Petrofrac, Metro CSG, Christus Health
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Uptycs and other solutions. Updated: September 2026.
915,341 professionals have used our research since 2012.