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Microsoft Defender for Business vs Uptycs comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender for Busi...
Ranking in Endpoint Protection Platform (EPP)
14th
Average Rating
7.6
Reviews Sentiment
6.6
Number of Reviews
20
Ranking in other categories
Microsoft Security Suite (14th)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
44th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (36th), Endpoint Detection and Response (EDR) (48th), Cloud Workload Protection Platforms (CWPP) (23rd), Extended Detection and Response (XDR) (40th), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of September 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.8% compared to the previous year. The mindshare of Microsoft Defender for Business is 1.4%, down from 2.1% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.8%
Microsoft Defender for Business1.4%
Uptycs0.5%
Other94.3%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Paritosh Jani - PeerSpot reviewer
Associate VP (Managed Information Technology Services) at Dev Information Tech Pvt Ltd
Has delivered automated threat response and streamlined integration with advanced tools
The best features of Microsoft Defender for Business include it coming as an XDR solution which provides automated investigations, remediations, and endpoint detection and response. Moreover, it can be tightly integrated with vulnerability management or detecting vulnerabilities and pushing them to the SIEM solution. I utilize the advanced threat hunting feature of Microsoft Defender for Business and find it helpful; it's good and improving with every update. Microsoft Defender for Business integrates effectively with the Microsoft ecosystem as with Azure Sentinel, and it has a two-way natural integration. Apart from that, it also integrates with industry SIEM solutions such as Splunk.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The best feature of Cortex XDR by Palo Alto Networks is that it collects logs from different sections such as the endpoint, the network, and the cloud, making it easy to investigate alerts, collect some of the investigation packages related to the infected machines, and provide live response."
"Implementing Cortex XDR by Palo Alto Networks has had a significant impact on my security analyst workload because it becomes much easier."
"The biggest positive impact I see from Cortex XDR by Palo Alto Networks is a significant reduction in the number of people required to manage it."
"The initial setup is easy."
"The initial setup isn't too bad."
"The most valuable feature of Cortex XDR by Palo Alto Networks is the low consumption of system resources. The solution uses a lot of AI and machine learning."
"Stability is a primary factor, and then there's the ease of distribution and policy management; Cortex XDR by Palo Alto Networks is very easy to work with, and we're quite happy with them."
"It detected stuff that other things wouldn't detect."
"I haven't had any problems with the tool's stability."
"Defender's main strength is its integration with Microsoft Sentinel, offering valuable insights."
"Because Microsoft Defender for Business is a native solution to Microsoft 365, it has contributed to my organization's proactive defense strategies by saving time on integration."
"I rate Microsoft Defender for Business a 10 out of 10."
"A few things are valuable. One is the alerting we see when any kind of intrusion is happening, any kind of malware is being deployed across the endpoints, or any kind of suspicious activity is going on. We have a footprint across all of North America, Canada, and Mexico, so we want to make sure that all our endpoints are protected and we are able to look for any anomalous activity."
"The most valuable feature of the solution is its central console."
"If you're an Intune user, you can bring in certain capabilities like system-hardening policies, which further enhances the security."
"Using Microsoft Defender for Business is beneficial for my company."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
"They have multiple great features."
 

Cons

"There are some limitations on the Traps agents."
"Being able to filter the events to see those that are related to the actual alert would save time spent by the engineer."
"Cortex XDR should have a lightweight agent, and the agent size should not be heavy."
"For working with the solution, you only really need a web browser, however, we've found that working on Chrome, for example, is horrible."
"Cortex XDR is trickier to configure than other Palo Alto products. This is one area where we are not so satisfied."
"Currently, if you use Palo Alto endpoint protection as the only solution it's very complicated to remove pre-existing threats."
"There is a severe gap in functionality between Windows, Linux, and Mac versions. For example all folder restriction settings are Windows only. Traps 5.0+ does not have SAML / LDAP integration."
"Technology evolves every day, so it would be nice if it gets more secure. It can also have more integration with other platforms."
"Threat protection could be improved even though it is already a built-in feature."
"I have an open case for close to two months with no responses or updates, except for an email response, and I've made four or five phone calls regarding the Microsoft Interconnect for AD and cloud tenant."
"Defender's threat protection should be fine-tuned to reduce false positives. It could be more targeted, reflecting a continuous evolution in detecting. Also, it could be easier to integrate into other environments."
"The biggest one is that Defender needs to be more proactive to the emerging threats. There can be tighter integration with email, especially how it integrates with our email system, which is the Microsoft Outlook suite. There should be the ability to react a lot quicker to emerging threats because sometimes, it takes a few days before some of these new threats are fully identified, and we need that to be a few hours."
"I see room for improvement in Microsoft Defender for Business, particularly regarding the consolidation of all security solutions in one place and the integration of AI and data security into the same platform."
"The tool's support is an area of concern where improvements are needed."
"I am not satisfied with Microsoft's technical support. There are challenges with the knowledge and experience of the support staff, frequent redirection between departments, and slow response times."
"Additionally, the pricing policy poses a challenge, particularly in multi-year contracts, where other solutions like Trend Micro offer more affordable options."
"We end up facing a lot of issues after upgrades."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
 

Pricing and Cost Advice

"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"Every customer has to pay for a license because it doesn't work with what you get from a managed services provider."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"Our license will require renewal in August, after which the maintenance will continue as usual."
"It is present, but when compared to other competitive products, I would say it is not less expensive; however, when all of the other added values are considered, the price is reasonable."
"Its pricing is kind of in line with its competitors and everybody else out there."
"I don't recall what the cost was, but it wasn't really that expensive."
"Since we're a nonprofit, we get pretty good discounts on the tool."
"The tool is cheap, while some other solutions are more expensive. I remember the tool cost about five euros for a workstation or for a user on a monthly basis."
"The tool's cost has been a little high, but I do not think it was terrible."
"It has to get more competitive because we are starting to see some of the competitors providing better pricing, and some of it, of course, is to gain market share. The Defender product pricing is probably a little higher than the competitors."
"Defender for Business is included by default with an Office 365 premium subscription."
Information not available
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Manufacturing Company
9%
Computer Software Company
14%
Comms Service Provider
10%
Outsourcing Company
10%
Financial Services Firm
8%
Computer Software Company
13%
Construction Company
11%
Comms Service Provider
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business15
Midsize Enterprise2
Large Enterprise4
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft Defender for Business?
Our thoughts on the pricing for Microsoft Defender for Business are that we wish it could be better. If the pricing w...
What needs improvement with Microsoft Defender for Business?
I see room for improvement in Microsoft Defender for Business, particularly regarding the consolidation of all securi...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
No data available
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Information Not Available
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender for Business vs. Uptycs and other solutions. Updated: September 2026.
914,394 professionals have used our research since 2012.