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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
7th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
108
Ranking in other categories
Endpoint Protection Platform (EPP) (5th), Extended Detection and Response (XDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (2nd)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
25th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (34th), Cisco Security Portfolio (7th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
75th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cortex XDR features advanced threat detection capabilities."
"The interface is easy to use and it is more up to date than our previous solution."
"Traps pays for itself within the first 16 months of a three-year subscription."
"Its interface and pricing are most valuable. It is better than other vendors in terms of security."
"Palo Alto is the core of the security infrastructure in the environment."
"Cortex is the best tool for endpoint detection, with playbooks that automate and gather endpoint logs, block malicious processes, and update incident tickets, showcasing end-to-end processes with automation in investigation and reducing the analysis workflow."
"Since they've done their most recent update, the ease to isolate endpoints is valuable. If we find one where there is a virus on it, we can easily isolate it. We don't even have to contact the user. We don't have to manually take them off the network. We can easily isolate them."
"The one feature of Palo Alto Networks Traps that our organization finds most valuable is the App ID service."
"One of the best features of AMP is its cloud feature. It doesn't matter where the device is in regards to whether it's inside or outside of your network environment, especially right now when everybody's remote and taken their laptops home. You don't have to be VPNed into the environment for AMP to work. AMP will work anywhere in the world, as long as it has an Internet connection. You get protection and reporting with it. No matter where the device is, AMP has still got coverage on it and is protecting it. You still have the ability to manage and remediate things. The cloud feature is the magic bullet. This is what makes the solution a valuable tool as far as I'm concerned."
"Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet."
"The biggest lesson that I have learned from using this product is that there is a lot more malware slipping through my email filters than I expected."
"The integration with other Cisco products seemed to be really effective. We had Umbrella in place and we were using AnyConnect as well as Firepower. Once a threat was detected, being able to do the threat lookups and the live tracking was really useful."
"I am told that we get over 100 million emails a month. This filters them down and allows only somewhere about three million emails, which is a great help."
"It used to take us a month to find out that something is infected, we now know that same day, as soon it is infected."
"Cisco has definitely improved our organization a lot. In terms of business, our company feels safer. We actually switched from legacy signature-based solutions to threat intelligence-based and machine learning-based solutions, which is Cisco Secure. This has improved our security significantly, from 10% of signature-based technology security to 99.9% of the current one which we are running. We were happy."
"The product provides sandboxing options like file reputation and file analysis."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"The solution should add unwanted malicious hash values to a block list so that whenever the action is triggered, it will automatically prevent the malicious content."
"I would like to see better protection, specifically to protect email applications."
"They have the worst support, as a company, that I have ever worked with, as they are difficult to get a hold of and keep on the phone."
"There are some limitations on the Traps agents."
"It is not a suitable solution if you are looking for a single product with multiple features such as DLP, encryption, rollback, etc."
"Managing the product should be easier."
"Cortex XDR by Palo Alto Networks could improve by adding a sandbox feature to better compete with their competitors which have it."
"Previously, the endpoint would leave the environment, not being on our VPN, essentially unable to interact with the server to upload files. It was unable to retrieve new file verdicts. It was using a thing called "local analysis" to determine if something was a malicious file or not. There was no dynamic analysis."
"The reporting and analytics areas of the solution need to be improved."
"The product does not provide options like tunnel creation or virtual appliances."
"The room for improvement would be on event notifications. I have mine tuned fairly well. I do feel that if you subscribe to all the event notification types out-of-the-box, or don't really go through and take the time to filter out events, the notifications can become overwhelming with information. Sometimes, when you're overwhelmed with information, you just say, "I'm not going to look at anything because I'm receiving so much." I recommend the vendor come up with a white paper on the best practices for event notifications."
"Previously, there were options to uninstall the agent without a password if you had admin access, and this could be improved."
"The thing I hate the most, which they have not fixed, is when it creates duplicate entries within a console. If you have a computer and you upgrade from Windows 7 to Windows 10, or you upgrade your agent from version 6 to 7, it creates a new instance in there instead of updating the information. Instead of paying a license for one computer, I have to license two computers until I manually go in, search for all the duplicate entries, and clean them out myself."
"In the next release, I would for it to have back up abilities. I would like the ability to go back to a point in time to when my PC was uninfected and to the moment of when the infection happened."
"It cannot currently block URLs over websites."
"The initial setup is a bit complex because you need to execute existing antiviruses or security software that you have on your device."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"Cortex XDR by Palo Alto Networks is an expensive solution."
"When we first bought it, it was a bit expensive, but it was worth it. The licensing was straightforward."
"I don't recall what the cost was, but it wasn't really that expensive."
"Traps pays for itself within the first 16 months of a three-year subscription. This is attributed to OPEX savings, as security teams spent less time trying to identify and isolate malware for analysis as a result of a reduction in malware incidents, false positives, and breach avoidance."
"The cost of Cortex XDR by Palo Alto Networks is $55 to $90 USD per endpoint per month."
"The tool's price is moderate."
"The cost depends on your chosen license type, like Pro or other licenses."
"If one wishes to work with another team or large number of users at a future point, he must purchase a license for them."
"We can know if something bad is potentially happening instantaneously and prevent it from happening. We can go to a device and isolate it before it infects other devices. In our environment, that's millions of dollars saved in a matter of seconds."
"...the licensing needs to be improved. All the product features we need are there. It's just a matter of the complexity and the different offerings and trying to figure things out."
"The costs of 50 licenses of AMP for three years is around $9,360."
"In our case, it is a straightforward annual payment through our Enterprise Agreement."
"I rate the pricing a five or six on a scale of one to ten, where one is expensive, and ten is cheap."
"​Pricing can be more expensive than similar software that does less functionality, but not recognized by customers.​"
"The pricing and licensing of the security solutions of Cisco are very good in comparison with the competitors, but sometimes, it's difficult to see all the discounts and other kinds of things. So, you have to be careful, but the pricing is good."
"Because we do see the value of what it's bringing, I think they have priced it well."
Information not available
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Top Industries

By visitors reading reviews
Computer Software Company
9%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
10%
Computer Software Company
10%
Government
8%
Healthcare Company
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business44
Midsize Enterprise20
Large Enterprise47
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What do you like most about Cisco Secure Endpoint?
The product's initial setup phase was very simple.
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
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