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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
6th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
110
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (5th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (32nd), Cisco Security Portfolio (8th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
70th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cortex XDR lets us manage several clients from the same console, and its endpoint defense is more advanced than traditional antivirus."
"I generally believe that Cortex XDR by Palo Alto Networks is probably the best in the market right now."
"Monitoring is most valuable."
"Stability is one of the features we like the most."
"It's very stable. I've never experienced downtime for the ASM console or ASM core."
"One thing that I like about Cortex XDR by Palo Alto Networks, it is detecting all the suspicious or malicious binaries, and it has integration with Palo Alto Firewall."
"I have found the solution to be very easy in respect of the integration and configurable."
"It integrates well into the environment."
"The visibility and insight this solution gives you into threats is pretty granular. It has constant monitoring. You can get onto the device trajectory to look at a threat, but you can also see what happened prior to the threat. You can see what happened after the threat. You can see what other applications were incorporated into the execution of the threat. For example, you have the event, but you see that the event was launched by Google Chrome, which was launched by something else. Then, after the event, something else was launched by whatever the threat was. Therefore, it gives you great detail, a timeline, and continuity of events leading up to whatever the incident is, and then, after. This helps you understand and nail down what the threat is and how to fix it."
"It used to take us a month to find out that something is infected, we now know that same day, as soon it is infected."
"It doesn't impact the devices. It is an agent-based solution, and we see no performance knock on cell phones. That was a big thing for us, especially in the mobile world. We don't see battery degradation like you do with other solutions which really drain the battery, as they're constantly doing things. That can shorten the useful life of a device."
"If you are looking for a long term security solution, this particular solution is going to add value to your cybersecurity strategy."
"The entirety of our network infrastructure is Cisco and the most valuable feature is the integration."
"The solution's integration capabilities are excellent. It's one of the best features."
"The integration with other Cisco products seemed to be really effective. We had Umbrella in place and we were using AnyConnect as well as Firepower. Once a threat was detected, being able to do the threat lookups and the live tracking was really useful."
"Any alert that we get is an actionable alert. Immediately, there is information that we can just click through, see the point in time, what happened, what caused it, and what automatic actions were taken. We can then choose to take any manual actions, if we want, or start our investigation. We're no longer looking at digging into information or wading through hundreds of incidents. There's a list which says where the status is assigned, e.g., under investigation or investigation finished. That is all in the console. It has taken away a lot of the administration, which we would normally be doing, and integrated it into the console for us."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"The solution should offer more dashboards and they should be better customized."
"I would like to see some additional features related to email protection included."
"They've been having some issues with updating their endpoint agents, and it has been quite frustrating."
"I feel that it should not be a licensed activity because a feature should allow us to see applications running on end devices."
"I have seen lagging with Cortex XDR by Palo Alto Networks. There was one time when we faced a threat actor trying to gain access to our system. When our team utilized the tool, we were all on the same dashboard and we faced a lag issue at that time of around five minutes, which was quite significant."
"In the next release, I would like to see more UI improvements. Their UI is a bit basic. When we are speaking about Palo Alto Networks they are the big company, so they can improve the UI a little bit. The UI, the reports, the log system can all be improved."
"The MAC agent is not as robust feature-wise as the PC version."
"Every 30 or 40 days, there's a new version and we need to go and make sure our customer's laptops are upgraded."
"It does not include encryption and decryption of local file shares."
"The billing process for us is hard where we've got those two users."
"The thing I hate the most, which they have not fixed, is when it creates duplicate entries within a console. If you have a computer and you upgrade from Windows 7 to Windows 10, or you upgrade your agent from version 6 to 7, it creates a new instance in there instead of updating the information. Instead of paying a license for one computer, I have to license two computers until I manually go in, search for all the duplicate entries, and clean them out myself."
"The initial setup is a bit complex because you need to execute existing antiviruses or security software that you have on your device."
"I would recommend that the solution offer more availability in terms of the product portfolio and integration with third-party products."
"Maybe there is room for improvement in some of the automated remediation. We have other tools in place that AMP feeds into that allow for that to happen, so I look at it as one seamless solution. But if you're buying AMP all by itself, I don't know if it can remove malicious software after the fact or if it requires the other tools that we use to do some of that."
"The room for improvement would be on event notifications. I do feel that if you subscribe to all the event notification types out-of-the-box, or don't really go through and take the time to filter out events, the notifications can become overwhelming with information."
"We don't have issues. We think that Cisco covers all of the security aspects on the market. They continue to innovate in the right way."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"Every customer has to pay for a license because it doesn't work with what you get from a managed services provider."
"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"The pricing is a little bit on the expensive side."
"It's way too expensive, but security is expensive. You pay for your licensing, and then you pay for someone to monitor the stuff."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"Cortex XDR’s pricing is very reasonable."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"We can know if something bad is potentially happening instantaneously and prevent it from happening. We can go to a device and isolate it before it infects other devices. In our environment, that's millions of dollars saved in a matter of seconds."
"The price is very good."
"The costs of 50 licenses of AMP for three years is around $9,360."
"Because we do see the value of what it's bringing, I think they have priced it well."
"The pricing and licensing fees are okay."
"Licensing fees are on a yearly basis and I am happy with the pricing."
"Cisco's pricing is reasonable. We also do not need to opt for niche players, which would have charged us significantly more than Cisco for ecosystem solutions. We are highly satisfied with the pricing structure of Cisco's solutions they are reasonable."
"It is a subscription-based product."
Information not available
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Top Industries

By visitors reading reviews
Financial Services Firm
12%
Construction Company
12%
Comms Service Provider
9%
Manufacturing Company
8%
Manufacturing Company
10%
Comms Service Provider
8%
Government
8%
Financial Services Firm
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business45
Midsize Enterprise21
Large Enterprise48
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What do you like most about Cisco Secure Endpoint?
The product's initial setup phase was very simple.
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
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