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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (26th), Cisco Security Portfolio (7th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
70th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of September 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.6%, down from 3.9% compared to the previous year. The mindshare of Cisco Secure Endpoint is 1.3%, down from 1.6% compared to the previous year. The mindshare of MetaDefender Endpoint is 0.4%. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.6%
Cisco Secure Endpoint1.3%
MetaDefender Endpoint0.4%
Other94.7%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"On a scale from one to ten, I would rate Cortex XDR by Palo Alto Networks a nine."
"Overall, it's a great platform; it integrates very well with other solutions from Palo Alto and also with our vendors, the ease of use is excellent, I love the root cause analysis from Cortex, which is amazing, and in a few clicks you can have the full root cause."
"The most valuable features of this product are the management capabilities, which allow an IT organization to get quite a good picture of attempted cyber attacks, and its out-of-the-box investigation capabilities."
"One of the main benefits of the solution is its intelligence to correlate the events into an incident."
"Cortex XDR by Palo Alto Networks should be a stable solution."
"The most valuable feature of Cortex XDR by Palo Alto Networks is the low consumption of system resources. The solution uses a lot of AI and machine learning."
"We think that this product will help us grow, as it meets our needs currently and we can grow with it over time."
"The solution is a new generation XDR that has a lot of artificial intelligence modules."
"With Cisco AMP, Threat Response, and Orbital, we are 100 percent certain that we got every trace of malicious software."
"I can't think of a case where a computer was infected and AMP did not let us know or missed it."
"For the initial first level of support, we provide it from our side. If there's escalation required, we use Cisco tech for the AMP. And again, they are perfect. I mean, one of the best, compared to any other vendors."
"The entirety of our network infrastructure is Cisco and the most valuable feature is the integration."
"The product provides sandboxing options like file reputation and file analysis."
"I am told that we get over 100 million emails a month. This filters them down and allows only somewhere about three million emails, which is a great help."
"The product itself is pretty reliable. The security features that it has make it reliable."
"I did the initial setup myself and it was really easy and straightforward."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"It'll help if customization was easier."
"They are charging for Network Traffic Analyzer (NTA) services, so if the per GB data could be provided at a certain level free of cost or at the same cost which the customer is taking for the entire bundle, that would be better."
"Impact on system performance is horrible, adding a lot of delays for users."
"The MAC agent is not as robust feature-wise as the PC version."
"It's not an ideal choice for smaller businesses, as you need a minimum of 200 endpoints to even use the solution at all."
"Product might have some bugs."
"As an improvement, I would like to see enhanced connection speeds."
"If he is using a smaller company, he can depend on some other tools because Cortex XDR by Palo Alto Networks is a bit expensive."
"In the next release, I would for it to have back up abilities. I would like the ability to go back to a point in time to when my PC was uninfected and to the moment of when the infection happened."
"We have had some problems with updates not playing nice with our environment."
"In Orbital, there are tons of prebuilt queries, but there is not a lot of information in lay terms."
"The technical support is very slow."
"I would like more seamless integration, because I have a security solution based on Cisco and I'm looking at integration for the old solution."
"It cannot currently block URLs over websites."
"...the greatest value of all, would be to make the security into a single pane of glass. Whilst these products are largely integrated from a Talos perspective, they're not integrated from a portal perspective. For example, we have to look at an Umbrella portal and a separate AMP portal. We also have to look at a separate portal for the firewalls. If I could wave a magic wand and have one thing, I would put all the Cisco products into one, simple management portal."
"It is not very stable because we have new versions four times a year, which fixes bugs. We had some problems with some deployments."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"I don't have any issues with the pricing. We are satisfied with the price."
"Very costly product."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"Its pricing is kind of in line with its competitors and everybody else out there."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"Its price is fair for us."
"The solution is highly affordable; I believe we pay $2 or $3 per endpoint. It's significantly cheaper than the competitors on the market."
"We had faced some license issues, but it has been improved. At the beginning of the implementation, we faced a lot of licensing issues, but now, we have EA licensing, which gives us an opportunity to grow."
"It is an expensive solution."
"The pricing and licensing are reasonable. The cost of AMP for Endpoints is inline with all the other software that has a monthly endpoint cost. It might be a little bit higher than other antivirus type products, but we're only talking about a dollar a month per user. I don't see that cost as being an issue if it's going to give us the confidence and security that we're looking for. We have had a lot of success and happiness with what we're using, so there's no point in changing."
"​Pricing can be more expensive than similar software that does less functionality, but not recognized by customers.​"
"It is a subscription-based product."
"Because we do see the value of what it's bringing, I think they have priced it well."
Information not available
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Financial Services Firm
9%
Manufacturing Company
10%
Outsourcing Company
8%
Financial Services Firm
8%
Construction Company
8%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise15
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What is your primary use case for Cisco Secure Endpoint?
We deployed Cisco Secure Endpoint for our customers two to three years back. The use case was to secure their endpoin...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
Find out what your peers are saying about SentinelOne, CrowdStrike, Microsoft and others in Endpoint Detection and Response (EDR). Updated: September 2026.
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