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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.6
Reviews Sentiment
6.7
Number of Reviews
122
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (3rd), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
27th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (28th), Cisco Security Portfolio (8th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
69th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of November 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, down from 3.8% compared to the previous year. The mindshare of Cisco Secure Endpoint is 1.4%, down from 1.6% compared to the previous year. The mindshare of MetaDefender Endpoint is 0.4%, up from 0.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.8%
Cisco Secure Endpoint1.4%
MetaDefender Endpoint0.4%
Other94.4%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Stability is one of the features we like the most."
"The correlation with the firewall and the creation of policies by areas have facilitated security management in my company by allowing me to create more fine-tuned policies that take into account multiple aspects of the operation, multiple effects, multiple sources, and multiple destinations."
"The most valuable aspect of Cortex XDR by Palo Alto Networks for me is its integration with AI detection, where we get to know the behavioral detection based on users, traffic patterns, and different services that we consume."
"The stability is pretty good except for one or two cases, and based on the performance, it's been okay with pretty high performance, no bugs or glitches, and it doesn't crash or freeze."
"The most valuable features are incident creation, policy-based protection, IP whitelisting, and device encryption. These are beneficial for endpoint and server security."
"One major outcome our organization achieved with Cortex XDR by Palo Alto Networks is that it is a good tool for analysis, remediation, and incident response, with no negative points in terms of budget and overall effectiveness."
"The solution's most valuable feature is the user interface."
"Technical support is the best in class, in my opinion, because they have invested heavily in research and development."
"The most valuable feature is signature-based malware detection."
"We have been very happy with it."
"The most valuable feature is its threat protection and data privacy, including its cyber attack and data protection, as we need to cover and protect data on user devices."
"If somebody has been compromised, the question always is: How has it affected other devices in the network? Cisco AMP gives you a very neat view of that."
"The solution is easy to deploy and applies multi-factor authentication."
"Cisco AMP is the broadest, most integrated security platform that connects the breadth of Cisco's integrated security portfolio and the customer's infrastructure for a consistent experience."
"The most valuable feature of the solution is its technical support."
"The solution's stability is perfect."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"It is a complex solution to implement."
"I would rate it an 8 rather than a 10 mainly because there is still room to improve the user experience around complex investigations, including alert tuning and third-party integration."
"Technology evolves every day, so it would be nice if it gets more secure. It can also have more integration with other platforms."
"Cortex XDR should have a lightweight agent, and the agent size should not be heavy."
"I think sometimes Cortex XDR agent automatically stops event capturing from the device, and then even the dashboard does not get any notifications from the agent."
"The tool needs to be improved in terms of integration and interface."
"The solution should offer more dashboards and they should be better customized."
"There are some third-party solutions that are difficult to integrate with, which is something that can be improved."
"The integration of the Cisco products for security could be better in the sense that not everything is integrated, and they aren't working together. In addition, not all products are multi-tenant, so you can't separate different customer environments from each other, which makes it a little bit hard for a managed service provider to deliver services to the customers."
"In terms of the user experience, if the UX design could be much simpler [that would improve things]... if they could make it more intuitive for someone who is not an engineer so that they still can read what's going on in their webpage and understand, that would be something."
"...the greatest value of all, would be to make the security into a single pane of glass. Whilst these products are largely integrated from a Talos perspective, they're not integrated from a portal perspective. For example, we have to look at an Umbrella portal and a separate AMP portal. We also have to look at a separate portal for the firewalls. If I could wave a magic wand and have one thing, I would put all the Cisco products into one, simple management portal."
"One of the things that Cisco Secure Endpoint really needs is that it's not just Secure Endpoint, it's a point product, and I think we really need to move into solution-based selling, designing, and architecting. So that we're not worried about putting things on endpoints and selling 'x' amount of endpoints, but to provide a solution that covers all of the remote access and sell them as solutions that cover multiple things."
"Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with third-party tools need improvement."
"It could be improved in connection with artificial intelligence and IoT."
"This product has issues with the number of false positives that it reports."
"The initial setup is a bit complex because you need to execute existing antiviruses or security software that you have on your device."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"The price of the solution is high for the license and in general."
"It is "expensive" and flexible."
"This is an expensive solution."
"The price is on the higher side, but it's okay."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"I am using the Community edition."
"The pricing is a little high. It is per user per year."
"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"The price is very good."
"The costs of 50 licenses of AMP for three years is around $9,360."
"We had faced some license issues, but it has been improved. At the beginning of the implementation, we faced a lot of licensing issues, but now, we have EA licensing, which gives us an opportunity to grow."
"Our company was very happy with the price of Cisco AMP. It was about a third of what we were paying for System Center Endpoint Protection."
"The visibility that we have into the endpoint and the forensics that we're able to collect give us value for the price. This is not an overly expensive solution, considering all the things that are provided. You get great performance and value for the cost."
"It is a subscription-based product."
"In our case, it is a straightforward annual payment through our Enterprise Agreement."
"There are a couple of different consumption models: Pay up front, or if you have an enterprise agreement, you can do a monthly thing. Check your licensing possibilities and see what's best for your organization."
Information not available
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Top Industries

By visitors reading reviews
Comms Service Provider
14%
Outsourcing Company
12%
Construction Company
10%
Manufacturing Company
10%
Manufacturing Company
12%
Outsourcing Company
9%
Financial Services Firm
9%
Construction Company
8%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business50
Midsize Enterprise21
Large Enterprise57
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise15
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
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Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What is your primary use case for Cisco Secure Endpoint?
We deployed Cisco Secure Endpoint for our customers two to three years back. The use case was to secure their endpoin...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
Find out what your peers are saying about CrowdStrike, SentinelOne, Microsoft and others in Endpoint Detection and Response (EDR). Updated: October 2026.
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