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Cisco Secure Email Threat Defense vs SafeGuard Cyber Security comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
SafeGuard Cyber Security
Ranking in Email Security
35th
Average Rating
8.0
Reviews Sentiment
6.8
Number of Reviews
1
Ranking in other categories
Data Loss Prevention (DLP) (33rd)
 

Mindshare comparison

As of May 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.9%, down from 18.3% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of SafeGuard Cyber Security is 0.0%, up from 0.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Sonu Kumar - PeerSpot reviewer
Helps to monitor everything – from the firewall to endpoint protection, all within a single software
The tool lets us monitor everything – from the firewall to endpoint protection, all within a single software We use different vendors for various aspects like cybersecurity policy and DLP implementation. SafeGuard Cyber Security is expensive. It needs to improve the data server as well.  I have…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Overall, I would rate Microsoft Defender for Office 365 at a ten."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"Defender helps us prioritize threats across our organization."
"The stability of Microsoft Defender for Office 365 is fantastic."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"It has an efficient email filtering feature."
"Secure Email Threat Defense's scalability is good."
"It's very easy to deploy and configure."
"This solution is easy to use."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"The tool lets us monitor everything – from the firewall to endpoint protection, all within a single software."
 

Cons

"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"There's room for improvement regarding the time frame for retrieving emails."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"We still see many false positives from time to time with Microsoft Defender for Office 365, so it would be good if we can reduce those false positives and provide better workflows for our end users, as sometimes they may not know what to do when they encounter a false positive."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"The XDR dashboard has room for improvement."
"The pricing could always be better."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The solution is a bit expensive."
"We encounter issues while searching for missing emails."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The physical appliance has been discontinued, although the platform still exists."
"We use different vendors for various aspects like cybersecurity policy and DLP implementation. SafeGuard Cyber Security is expensive. It needs to improve the data server as well."
 

Pricing and Cost Advice

"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"The pricing has become expensive."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is expensive."
"It's a user-base subscription."
"The solution’s pricing is manageable."
"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
Information not available
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
8%
Manufacturing Company
8%
Government
6%
Computer Software Company
35%
Financial Services Firm
6%
Government
5%
Healthcare Company
5%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What do you like most about SafeGuard Cyber Security?
The tool lets us monitor everything – from the firewall to endpoint protection, all within a single software.
What needs improvement with SafeGuard Cyber Security?
We use different vendors for various aspects like cybersecurity policy and DLP implementation. SafeGuard Cyber Securi...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
No data available
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Microsoft, Proofpoint, Cisco and others in Email Security. Updated: May 2025.
851,042 professionals have used our research since 2012.