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Cisco Secure Email Threat Defense vs MetaDefender Email Security Solutions comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
MetaDefender Email Security...
Ranking in Email Security
28th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
3
Ranking in other categories
Secure Email Gateway (SEG) (10th)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of MetaDefender Email Security Solutions is 0.4%, up from 0.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Aaron Alornyenu - PeerSpot reviewer
Helps us stay compliant, has excellent malware detection, and is stable
The solution helped our organization stay 100 percent compliant with industry standards. MetaDefender Email Security can be set to be very aggressive for identifying attacks. This can be done based on how we want it. If we set it to this level, most of our emails will be blocked because the system will block anything that looks suspicious. We will also need to set the spam severity. This is the severity of everything, including phishing, spoofing, and other types of attacks. I would give the solution's ability to identify attacks a nine out of ten. MetaDefender helps us improve our spam catch rate. Any spam we receive is usually due to user subscriptions. We can specify rules of exclusion to meet our requirements as well. It also detects and blocks the links with suspicious codes. MetaDefender Email Security's multi-scanning capabilities for malware detection work based on how we set the parameters. The solution perfectly detects malware. MetaDefender can identify and disarm emails in zero-day attacks.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"It also gives the vulnerability status according to the versions you have selected. Let's say you have Google Chrome. It mentions the versions it has, and it updates. Within two hours of an update, it is reflected in the dashboard. That's really nice to have."
"Defender helps us prioritize threats across our organization."
"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."
"Microsoft Defender has a feature to protect each and every attachment. Even if it's an encrypted attachment, it will check for any potential threats."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"We use Microsoft Defender for its ability to integrate with existing business technologies, which is beneficial for protecting business areas."
"Microsoft Defender for Office 365 is a stable solution."
"The solution is stable."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"I highly recommend it as one of the best choices."
"It's very easy to deploy and configure."
"It has an efficient email filtering feature."
"The product offers protection, email security, anti-spam, and antivirus."
"This solution is easy to use."
"The most valuable feature is called summary reconstruction which is used to deliver encrypted files to users."
"The sanitization is very good."
"The most valuable feature of MetaDefender Email Security is the CDR. Customers purchase this solution specifically for data communication, as the other features can be obtained through other technologies that most customers already possess. Therefore, data communication serves as the foundation for the platform."
 

Cons

"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"There's room for improvement regarding the time frame for retrieving emails."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"The GUI is sometimes slow to fetch the device report and could be improved."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"The UI needs to be more user-friendly."
"They can improve their security in a way where a customer can know if all their attachments are safe or not to open through a report. The solution does its job perfectly, but it never reports to the customer whether those attachments have been stopped before or not."
"There needs to be an improvement in integrating the product to work across multiple operating systems, and to have better support for non-Microsoft file types."
"We encounter issues while searching for missing emails."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The pricing could always be better."
"The solution is a bit expensive."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The DLP should be upgraded and has room for improvement."
"Although the number of AV engines is good, it could be better."
"They offer a feature called SmartLink neutralization. I have tried it before. It seemed to work most of the time; however, I had a few users for whom it just wouldn't work. Whenever they click on a link, it stays on the MetaDefender page, saying that it's scanning it and never moves forward."
 

Pricing and Cost Advice

"The pricing has become expensive."
"The product is expensive."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"I know that the product is incredibly expensive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"According to our customers, the price of MetaDefender is high and it continues to increase by almost 15 percent each year."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
29%
Healthcare Company
7%
Government
6%
Manufacturing Company
6%
Computer Software Company
14%
Comms Service Provider
12%
Educational Organization
11%
Financial Services Firm
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is your experience regarding pricing and costs for MetaDefender Email Security Solutions?
We paid for a three-year agreement. The cost is kind of high. For smaller companies, it may be outside of their budge...
What needs improvement with MetaDefender Email Security Solutions?
They offer a feature called SmartLink neutralization. I have tried it before. It seemed to work most of the time; how...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
OPSWAT MetaDefender Email Security, MetaDefender Email Gateway Security, MetaDefender Email Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. MetaDefender Email Security Solutions and other solutions. Updated: June 2025.
858,469 professionals have used our research since 2012.