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Cisco Secure Email Threat Defense vs MetaDefender Email Security Solutions comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
MetaDefender Email Security...
Ranking in Email Security
25th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
3
Ranking in other categories
Secure Email Gateway (SEG) (10th)
 

Mindshare comparison

As of May 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.9%, down from 18.3% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of MetaDefender Email Security Solutions is 0.4%, up from 0.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Aaron Alornyenu - PeerSpot reviewer
Helps us stay compliant, has excellent malware detection, and is stable
The solution helped our organization stay 100 percent compliant with industry standards. MetaDefender Email Security can be set to be very aggressive for identifying attacks. This can be done based on how we want it. If we set it to this level, most of our emails will be blocked because the system will block anything that looks suspicious. We will also need to set the spam severity. This is the severity of everything, including phishing, spoofing, and other types of attacks. I would give the solution's ability to identify attacks a nine out of ten. MetaDefender helps us improve our spam catch rate. Any spam we receive is usually due to user subscriptions. We can specify rules of exclusion to meet our requirements as well. It also detects and blocks the links with suspicious codes. MetaDefender Email Security's multi-scanning capabilities for malware detection work based on how we set the parameters. The solution perfectly detects malware. MetaDefender can identify and disarm emails in zero-day attacks.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Scalability-wise, I do not think there are any issues so far."
"My experience with customer support and technical support for Microsoft Defender for Office 365 has been excellent."
"The email protection is excellent, especially in terms of anti-phishing policies."
"The technical support is good and quick to resolve issues."
"The ability to respond to threats if very important."
"Microsoft Defender for Office 365 helps people to work remotely. It is a secure solution. We don't need to use our company's computers or get VPN connections to the networks. I can control how they share screens and what they send to the devices. It keeps our organizations confidential and sensitive information safe."
"Some of the valuable features on the email side are anti-phishing, anti-malware, and Safe Links."
"The two main features that prove most beneficial for us are URL scanning and attachment scanning."
"This solution is easy to use."
"It has an efficient email filtering feature."
"I highly recommend it as one of the best choices."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The solution is stable."
"It's very easy to deploy and configure."
"Secure Email Threat Defense's scalability is good."
"The sanitization is very good."
"The most valuable feature of MetaDefender Email Security is the CDR. Customers purchase this solution specifically for data communication, as the other features can be obtained through other technologies that most customers already possess. Therefore, data communication serves as the foundation for the platform."
"The most valuable feature is called summary reconstruction which is used to deliver encrypted files to users."
 

Cons

"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"Several simulation options are available within 365, and the phishing simulation could be better."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"The certification training for Defender for 365 needs to be deeper and incorporate Sentinel. I took all the security courses except one, and Sentinel isn't included."
"The pre-sales cost calculations could be more transparent."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats. For example, information about best practices on how to protect their own devices against hackers and scammers, such as educational information or training. This would help others have a better understanding of cyber security. Additionally, there can be more security features added."
"There is room for improvement in terms of reporting."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"The solution is a bit expensive."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The physical appliance has been discontinued, although the platform still exists."
"This solution could be improved by integration with Sandbox."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"We encounter issues while searching for missing emails."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Although the number of AV engines is good, it could be better."
"The DLP should be upgraded and has room for improvement."
"They offer a feature called SmartLink neutralization. I have tried it before. It seemed to work most of the time; however, I had a few users for whom it just wouldn't work. Whenever they click on a link, it stays on the MetaDefender page, saying that it's scanning it and never moves forward."
 

Pricing and Cost Advice

"The license is expensive because the cost is based on the number of users."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"The product is expensive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"According to our customers, the price of MetaDefender is high and it continues to increase by almost 15 percent each year."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
8%
Manufacturing Company
8%
Government
6%
Computer Software Company
36%
Healthcare Company
5%
Manufacturing Company
5%
Comms Service Provider
5%
Computer Software Company
12%
Educational Organization
11%
Comms Service Provider
11%
Government
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Money-wise, it is a part of the Office 365 ( /products/office-365-reviews ) suite, making it slightly more expensive ...
What needs improvement with Microsoft Defender for Office 365?
The main area for improvement is simplifying the implementation and rollout process. There are many conditions to be ...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is your experience regarding pricing and costs for MetaDefender Email Security Solutions?
We paid for a three-year agreement. The cost is kind of high. For smaller companies, it may be outside of their budge...
What needs improvement with MetaDefender Email Security Solutions?
They offer a feature called SmartLink neutralization. I have tried it before. It seemed to work most of the time; how...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
OPSWAT MetaDefender Email Security, MetaDefender Email Gateway Security, MetaDefender Email Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. MetaDefender Email Security Solutions and other solutions. Updated: April 2025.
850,236 professionals have used our research since 2012.