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Palo Alto Networks VM-Series vs Trellix Advanced Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Palo Alto Networks VM-Series
Ranking in Advanced Threat Protection (ATP)
16th
Average Rating
8.6
Reviews Sentiment
6.9
Number of Reviews
66
Ranking in other categories
Firewalls (15th)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of October 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Palo Alto Networks VM-Series is 2.6%, up from 2.2% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Palo Alto Networks VM-Series2.6%
Trellix Advanced Threat Defense2.1%
Other95.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

MuhammadNadeem - PeerSpot reviewer
Sr. Network Engineer at a tech services company with 1-10 employees
Has supported urgent deployments and enabled inline threat protection but pricing and features could be more flexible
I am not using Palo Alto Networks VM-Series mostly, but based on my experience, there are some deficiencies in Palo Alto Networks VM-Series. Having those features missing, we are not proposing Palo Alto Networks VM-Series to all customers. However, for urgency and for some solutions that customers need for some of their other sites and subdivisions, we are providing the same.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I highly recommend this service compared to other vendors."
"In the newer version, there are 3850s, all of them are scalable. They fit better into the medium or small businesses."
"It scales linearly with load and no issues."
"The most effective features for threat prevention include the threat prevention signature level, the application filter capability, and the visibility provided by the firewalls."
"It is very stable. It is fairly easy to use."
"The initial setup was straightforward."
"Scalability is a strength of Palo Alto VM-Series."
"In Palo Alto the most important feature is the App-ID."
"I recommend this solution because of its ease of use."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"This solution is very easy to use and requires little to no training."
"The product is expensive, but it is better than the rest of them in the industry."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"The most valuable features are the administration console and its detection and response module."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"Provides good exfiltration, and is an all-in-one product."
 

Cons

"It is not very easy to scale up the solution."
"We don't know how it will scale once we start putting more load on it."
"An improvement could be the integration of security intelligence with Palo Alto cloud via APIs."
"The solution needs to improve its visibility. It's not straightforward to use. Understanding the policies, authorizations, and initializing features requires careful review. The product needs to offer proper training."
"Its web interface is a bit outdated, and it needs to be updated. They can also improve the NAT functionality. We have had issues with the NAT setup."
"The one issue that I didn't like is that the SNMP integration with interfaces didn't record the interface counters."
"With Palo Alto Networks VM-Series, it is hard for me to manage its network configuration part."
"The product could provide protection above Layer 3, which gets into the application layer and provides better visibility into those aspects of application security."
"This solution needs to be made "cloud ready"."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"This product does the job, but it is not flexible enough to do new environments yet."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"Make the ATD appliance a part of the whole product offering and take the whole thing onto the cloud."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
 

Pricing and Cost Advice

"Palo Alto Networks VM-Series is an expensive product but the best one in the market."
"The price is not bad. They have a yearly renewal fee, and the pricing is exactly where we expect it to be."
"We found purchasing process the product on the AWS Marketplace to be very good."
"The VM series is licensed annually."
"The pricing and licensing of this product on AWS should be from $1.28/hr or $4,500.00/yr. Then, it would be a good price for the performance that it delivers."
"The cost of this product varies from customer to customer and the relationship with IBM, including how many offerings from IBM are already being used."
"It is not the cheapest on the market. The total cost for two firewall instances is $75,000. This includes licenses, deployment fees, and support for two years."
"The pricing and licensing are reasonable."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Outsourcing Company
14%
Comms Service Provider
11%
Manufacturing Company
11%
Financial Services Firm
9%
Construction Company
15%
Outsourcing Company
15%
Comms Service Provider
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise15
Large Enterprise24
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

Features comparison between Palo Alto and Fortinet firewalls
In the best tradition of these questions, Feature-wise both are quite similar, but each has things it's better at, it kind of depends what you value most. PA is good at app control, web filtering a...
How does Azure Firewall compare with Palo Alto Networks VM Series?
Both products are very stable and easily scalable. The setup of Azure Firewall is easy and very user-friendly and the overall cost is reasonable. Azure Firewall offers a solid threat awareness, can...
What is your experience regarding pricing and costs for Palo Alto Networks VM-Series?
The pricing is more on the expensive side, but it is justified due to its functionality, reliability, and throughput, even with all features enabled. In comparison to FortiGate ( /products/fortinet...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

No data available
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Warren Rogers Associates
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Palo Alto Networks VM-Series vs. Trellix Advanced Threat Defense and other solutions. Updated: September 2026.
915,341 professionals have used our research since 2012.