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Cisco Secure Email Threat Defense vs Trend Micro InterScan Messaging Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
15
Ranking in other categories
No ranking in other categories
Trend Micro InterScan Messa...
Ranking in Email Security
35th
Average Rating
7.0
Reviews Sentiment
7.1
Number of Reviews
3
Ranking in other categories
Secure Email Gateway (SEG) (14th)
 

Mindshare comparison

As of August 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Trend Micro InterScan Messaging Security is 0.6%, up from 0.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Abdul  Waris - PeerSpot reviewer
Deploy features like DLP and BEC for enhanced security
Multiple clients are using email security. We provide solutions based on what they need, and we configure them accordingly as per the requirement With Trend Micro email security gateway, we can deploy features like DLP and BEC. It includes Office 365 protection and sandboxing. This provides…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"I highly recommend it as one of the best choices."
"It has an efficient email filtering feature."
"Secure Email Threat Defense's scalability is good."
"The product offers protection, email security, anti-spam, and antivirus."
"It's very easy to deploy and configure."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The technical support services are excellent."
"The solution provides protection with its Email Track Records and Machine Manual features."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
"With Trend Micro email security gateway, we can deploy features like DLP and BEC."
 

Cons

"The physical appliance has been discontinued, although the platform still exists."
"This solution could be improved by integration with Sandbox."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"We encounter issues while searching for missing emails."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
"The solution's pricing could be improved."
"There is room for improvement in content filtration, expressions, file sharing, and policy configuration."
"The product's pricing could be more flexible."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"Trend Micro is an expensive solution."
"I rate Trend Micro InterScan Messaging Security’s pricing a seven out of ten."
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Top Industries

By visitors reading reviews
Computer Software Company
23%
Healthcare Company
8%
Government
6%
Manufacturing Company
6%
Performing Arts
12%
Manufacturing Company
11%
Financial Services Firm
10%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
The pricing for Cisco Secure Email Threat Defense is relatively high. For an organization that already has the legacy system, it makes sense to continue hosting it. However, new organizations might...
What needs improvement with Secure Email Threat Defense?
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilitie...
What is your primary use case for Secure Email Threat Defense?
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering,...
What is your experience regarding pricing and costs for Trend Micro InterScan Messaging Security?
The price is a bit high because the market is highly competitive. Multiple platforms are available, so we have to choose based on comparison.
What needs improvement with Trend Micro InterScan Messaging Security?
There is room for improvement in content filtration, expressions, file sharing, and policy configuration. We could decrease the price in email security gateway and cloud security services.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
InterScan Messaging Security
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Copa Airlines, Air21, BookMyShow, Bulgarian American Credit Bank, Canadian Museum of History, CIBIL, Community National Bank, Dar Al-Handasah
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Trend Micro InterScan Messaging Security and other solutions. Updated: July 2025.
865,384 professionals have used our research since 2012.