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Microsoft Exchange Online Protection (EOP) vs Proofpoint Email Protection comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.2
Microsoft Defender for Office 365 enhances email protection, reduces costs, and increases productivity, offering invaluable data security.
Sentiment score
7.6
Microsoft Exchange Online Protection enhances email security, reducing incidents and boosting productivity, yielding strong ROI in the US market.
Sentiment score
7.0
Proofpoint Email Protection effectively reduced threats and costs, excelling in phishing defense, leading to significant efficiency improvements.
It has also decreased our time to detection and response by about 15 to 20 percent.
Overall, cost of owning and operating our system goes down.
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
 

Customer Service

Sentiment score
7.0
Microsoft Defender for Office 365 offers reliable support, praised for responsiveness, despite some challenges with clarity and third-party resolutions.
Sentiment score
6.8
Microsoft Exchange Online Protection support quality varies, with premium users generally reporting more consistent and timely assistance.
Sentiment score
7.3
Proofpoint Email Protection's customer service is praised for responsiveness and expertise, though some report slow responses or portal issues.
Over the past two years, there have been no critical problems.
we opened tickets, and they typically resolve them quickly.
Customer service and support have been fantastic.
Microsoft offers excellent 24/7 support.
My team is able to get the help they need when necessary.
 

Scalability Issues

Sentiment score
8.2
Microsoft Defender for Office 365 scales seamlessly across configurations, supporting thousands of users with effortless integration and optimal performance.
Sentiment score
8.0
Microsoft Exchange Online Protection offers scalable, adaptable security, supporting diverse organizational needs with ease and high user satisfaction.
Sentiment score
7.6
Proofpoint Email Protection excels in adaptability and scalability, serving both small and large enterprises with ease and flexibility.
We have never faced scalability problems, and Microsoft manages it effectively.
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Proofpoint is scalable for multi-site organizations with thousands of users.
 

Stability Issues

Sentiment score
7.7
Microsoft Defender for Office 365 is highly reliable, offering stable performance, quick issue resolution, and high user satisfaction ratings.
Sentiment score
8.1
Microsoft Exchange Online Protection is highly rated for reliability and stability, with occasional management and configuration challenges noted.
Sentiment score
8.2
Users rate Proofpoint Email Protection highly for reliability and performance, with minor UI challenges and rare stability issues.
The solution is stable, as we have been using it for the past two years.
I would assess the stability and reliability of Microsoft Defender for Office 365 as very stable, with barely any issues.
Overall, the stability and reliability of Microsoft Defender for Office 365 are good.
 

Room For Improvement

Microsoft Defender for Office 365 needs enhanced virus protection, compatibility, UI, integration, reporting, and cost transparency to improve user experience.
Users desire improved automation, integration, security, pricing, reporting, email handling, stability, functionality, support, and clearer product distinctions in EOP.
Proofpoint Email Protection struggles with setup complexity, feature enhancements, pricing issues, and requires improved support and interface design.
The main area for improvement is simplifying the implementation and rollout process.
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
There is a different console for different things; I just want one consolidated console.
Improving the search process by allowing searches with different types of parameters and facilitating searches within emails would be advantageous.
Proofpoint could expand its phishing detection capabilities to improve its efficiency.
More security could be implemented.
I may advise Proofpoint to adjust marketing solutions based on each country.
 

Setup Cost

Enterprise users find Microsoft Defender for Office 365 pricing complex but valuable due to integration with Office 365 features.
Microsoft Exchange Online Protection offers valued security features despite varying costs, with flexible licensing in Microsoft 365 bundles.
Proofpoint Email Protection is considered costly, with pricing starting at $8 per user and varying by features.
We've likely saved 30% of costs.
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Microsoft is quite affordable with a lot of features available for any size organization.
The pricing is reasonable.
Microsoft Exchange is more expensive compared to other services like Gmail.
Customers pay around $90,000 yearly for a 1,000-user organization, with the subscription license being the main expense, apart from implementation fees.
Additional costs do come in, but it enhances security.
 

Valuable Features

Microsoft Defender for Office 365 offers comprehensive security with real-time updates and automated threat response, enhancing multi-platform enterprise safety.
Microsoft Exchange Online Protection provides scalable, user-friendly security with AI, ensuring robust anti-phishing and anti-malware protection for all businesses.
Proofpoint Email Protection offers advanced threat defense, user-friendly interface, and seamless Office 365 integration for comprehensive email security.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
The security features provided by Microsoft are robust.
It offers more features and better security, making it the best option for corporate environments.
In the last three years, has resulted in no antivirus problems.
The main feature I find most effective is that Proofpoint Email Protection scans emails and quarantines the doubtful ones.
The most beneficial feature of Proofpoint Email Protection is mostly spam filtering; it was very efficient, and we were very happy with the functionality as only relevant emails were allowed for mailboxes.
 

Categories and Ranking

Microsoft Defender for Offi...
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Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Microsoft Exchange Online P...
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
38
Ranking in other categories
Anti-Malware Tools (7th)
Proofpoint Email Protection
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Security Awareness Training (2nd), Digital Risk Protection (3rd), Office 365 Protection (2nd), Secure Email Gateway (SEG) (3rd)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 6.6%, down from 9.0% compared to the previous year. The mindshare of Proofpoint Email Protection is 8.2%, down from 11.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Amber Worth - PeerSpot reviewer
Retrieves data from quarantines and easy to read logs with robust security features
Some of the searchability when looking for specifics in Exchange logs is tedious. Although eventually the information is located, it can be difficult if detailed information is lacking. Improving the search process by allowing searches with different types of parameters and facilitating searches within emails would be advantageous. Simplifying interfaces would also be appreciated.
AhmedRamadan - PeerSpot reviewer
Optimize email security with effective sandboxing and auto Pull for quarantine
Proofpoint is used as an email security gateway for big enterprises, primarily for their on-premises servers. Many customers also use it alongside Office 365 Proofpoint offers a complete solution for email security with features like DLP, email archiving, and encryption. The most valuable…
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856,873 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
15%
Financial Services Firm
9%
Government
9%
Manufacturing Company
7%
Educational Organization
18%
Computer Software Company
14%
Financial Services Firm
9%
Manufacturing Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
I would like to improve the setting of rules in Microsoft Exchange Online Protection (EOP) as it is currently working...
What is your primary use case for Microsoft Exchange Online Protection?
I am using Microsoft Exchange Online Protection (EOP) ( /products/microsoft-exchange-online-protection-eop-reviews ) ...
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enh...
What needs improvement with Proofpoint Email Protection?
In terms of improvement, the price could be better. Additionally, more security could be implemented.
 

Also Known As

MS Defender for Office 365
Microsoft EOP, MS Exchange Online Protection
Proofpoint Enterprise Protection, Cofense PhishMe, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Information Not Available
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Microsoft Exchange Online Protection (EOP) vs. Proofpoint Email Protection and other solutions. Updated: June 2025.
856,873 professionals have used our research since 2012.