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Cisco Secure Client (including AnyConnect) vs ThreatLocker Zero Trust Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 17, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Cisco Secure Client enhances remote connectivity with robust security, ease of use, and varied ROI experiences across organizations.
Sentiment score
6.2
ThreatLocker enhances security, reduces costs, boosts productivity, and facilitates growth by blocking unauthorized applications and preventing malware.
With Cisco Secure Network Analytics implemented, we have achieved collaboration as an IT support team where we reached out to network-related members to understand how they work on Cisco Secure Network Analytics-related issues.
Intune Administrator at a consultancy with 11-50 employees
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
Tier 1 IT Engineer at a retailer with 11-50 employees
Based on what we use ThreatLocker Zero Trust Endpoint Protection Platform for with the same functionalities and packaging, it was around 13 or 14 hours.
Head Of Cyber Security at a outsourcing company with 201-500 employees
We have the MDR package as well, and just knowing someone is watching those endpoints at 3:00 a.m. is a lifesaver that you cannot put a dollar figure on.
System Administrator at Gwynedd Mercy University
 

Customer Service

Sentiment score
6.8
Cisco Secure Client provides reliable performance, with support generally quick and effective, though access sometimes requires contracts and has delays.
Sentiment score
7.8
ThreatLocker Zero Trust Platform excels in customer support with quick resolutions, expert assistance, and effective live chat services.
Cisco offers very high-quality customer service.
Manager - Network Services at a tech vendor with 10,001+ employees
Cisco technical support is difficult, and it requires lots of contracts.
Technical Manager at Gannexion BV
Over the years, there's been a decline in the quality, mainly in areas such as the experience level of support engineers and the time taken to address and escalate issues.
Director/ Senior Network Specialist at a computer software company with 51-200 employees
They have been very responsive, helpful, and knowledgeable.
Systems Security Analyst & Deputy Security Officer at a financial services firm with 201-500 employees
I would rate their customer support a ten out of ten.
Director, Managed Services at a consultancy with 11-50 employees
Their support is world-class.
Supervisor, Client Security at a consultancy with 11-50 employees
 

Scalability Issues

Sentiment score
7.3
Cisco Secure Client efficiently scales for organizations, providing secure access while integrating with existing infrastructures despite potential hardware challenges.
Sentiment score
7.8
ThreatLocker Zero Trust Platform seamlessly scales across organizations, managing thousands of endpoints, ensuring performance, and easy user integration.
A smaller firewall can handle fewer sessions, while a larger one can handle tens of thousands of sessions.
Director/ Senior Network Specialist at a computer software company with 51-200 employees
The scalability of Cisco Secure Client depends on the hardware I choose.
Network Architect at Sysnet Solutions Bangladesh Limited
Regarding scalability, Cisco Secure Client (including AnyConnect) rates as excellent because we can scale out by simply buying more licenses from the vendor.
Senior Network Engineer Specialist at Zenith Comp Co.,Ltd.
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
Technical Engineer at Cloud 1 Solutions
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
Systems Security Analyst & Deputy Security Officer at a financial services firm with 201-500 employees
ThreatLocker Zero Trust Endpoint Protection Platform scales very smoothly with our growing needs.
CEO at Mostro
 

Stability Issues

Sentiment score
8.0
Cisco Secure Client is praised for its stability and reliability, effectively handling remote connectivity despite minor flaws.
Sentiment score
7.9
Organizations find ThreatLocker Zero Trust Platform stable and reliable, with minor issues quickly resolved by support.
I would rate the stability ten out of ten.
Sr. I&C Enginner at Reliance Industries Ltd
The stability is really good, and I would rate it up to nine.
Manager - Network Services at a tech vendor with 10,001+ employees
Regarding the performance of Cisco Secure Client (including AnyConnect), I have not seen any issues because performance-wise it functions properly.
Manager - Projects at airtel
For five years, we have not had a problem.
Supervisor, Client Security at a consultancy with 11-50 employees
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
Information Cybersecurity Technology Specialist at Freez.it
It has been very stable, reliable, and accessible.
COO at Panda Technology
 

Room For Improvement

Cisco Secure Client faces usability and integration challenges, including outdated support, cumbersome authentication, and issues with pricing and technical support.
Users seek improved training, integrations, transparency, UI, and communication in ThreatLocker Zero Trust Platform for enhanced usability and administration.
I am using Intune for deployments, and it's not easy to create an automated deployment where users do not need to register server addresses.
Chief Technologies Officer at ASTORG PARTNERS
Vendors offer more features, such as a kill switch.
Technical Manager at Gannexion BV
Cisco's security portfolio, including Secure Client and the firewalls, is falling behind.
Director/ Senior Network Specialist at a computer software company with 51-200 employees
Controlling the cloud environment, not just endpoints, is crucial.
COO at Panda Technology
ThreatLocker Zero Trust Endpoint Protection Platform could improve by being a little more hands-off, perhaps by having a team inside ThreatLocker that does all the vetting of patches; having one person hired by ThreatLocker to check out patches means that a million other industries using ThreatLocker Zero Trust Endpoint Protection Platform do not have to vet the same patch, ultimately saving time and money around the world.
Technical Support Engineer at CMIT Solutions of Central Orlando
This feedback would help us understand what is learned in real-time, especially during a one-hour learning mode setup, ensuring we remain aware of potentially unnecessary learned items.
Server Administrator at Clay County Sheriff's Office
 

Setup Cost

Cisco Secure Client licensing offers flexible annual terms but is sometimes considered costly compared to Fortinet and Palo Alto.
ThreatLocker Zero Trust Platform provides flexible, scalable pricing with tiered plans and negotiable deals, ensuring cost-effectiveness and transparency.
Palo Alto and Fortinet provide free VPN connections, but Cisco Secure Client (including AnyConnect) requires a license purchase.
Senior Network Engineer Specialist at Zenith Comp Co.,Ltd.
I perceive the pricing to be a seven, however, I have perpetual licenses.
Technical Manager at Gannexion BV
The pricing seems to align equally with other competitors like Palo Alto during a competitive situation.
Director/ Senior Network Specialist at a computer software company with 51-200 employees
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
Director, Managed Services at a consultancy with 11-50 employees
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
Supervisor, Client Security at a consultancy with 11-50 employees
Money is saved because it is not costly, and I would suggest it for other companies.
Helpdesk Engineer at Computer Network Infrastructure (CNI) Consultants
 

Valuable Features

Cisco Secure Client provides reliable, cross-platform VPN access with multi-factor authentication and seamless Active Directory integration for enhanced security.
ThreatLocker Zero Trust Platform excels in app control, security features, and support, enhancing IT efficiency and company security.
Beneficial for businesses needing secure access outside the office.
Director/ Senior Network Specialist at a computer software company with 51-200 employees
Additionally, it gives the user flexibility of working from anywhere, which is a major feature we are looking at.
Manager - Projects at airtel
Cisco Secure Network Analytics filled the gap between the monitoring and management side, allowing us to check end user activity clearly from the Cisco Secure Network Analytics console.
Intune Administrator at a consultancy with 11-50 employees
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
Cyber Security Specialist at Bremmar Consulting
It protects our customers.
CTO at Zettabytes
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.
Tier 1 IT Engineer at a retailer with 11-50 employees
 

Categories and Ranking

Cisco Secure Client (includ...
Ranking in ZTNA as a Service
12th
Average Rating
8.4
Reviews Sentiment
6.6
Number of Reviews
79
Ranking in other categories
SSL VPN (3rd), Enterprise Infrastructure VPN (6th), Cisco Security Portfolio (5th)
ThreatLocker Zero Trust Pla...
Ranking in ZTNA as a Service
5th
Average Rating
9.2
Reviews Sentiment
7.1
Number of Reviews
82
Ranking in other categories
Network Access Control (NAC) (4th), Endpoint Protection Platform (EPP) (5th), Advanced Threat Protection (ATP) (4th), Application Control (1st), ZTNA (5th), Ransomware Protection (1st)
 

Mindshare comparison

As of August 2026, in the ZTNA as a Service category, the mindshare of Cisco Secure Client (including AnyConnect) is 2.8%, down from 3.6% compared to the previous year. The mindshare of ThreatLocker Zero Trust Platform is 1.3%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
ZTNA as a Service Mindshare Distribution
ProductMindshare (%)
ThreatLocker Zero Trust Platform1.3%
Cisco Secure Client (including AnyConnect)2.8%
Other95.9%
ZTNA as a Service
 

Featured Reviews

AS
Manager - Projects at airtel
Offers work-from-anywhere flexibility but navigates occasional proxy confusion
The analytics I downloaded from your site as a free download did not carry the information that was actually required. I was looking at the market segmentation and market share, along with some USPs which differentiated them from each other. The free download had two issues: many things were repetitive, and it was designed to not release any relevant information. Only headers were present, so I was not able to determine whether the final report would be worthwhile. I have not worked with enterprise tools that I could share feedback on for website publication. I see benefits from using Cisco Secure Client (including AnyConnect). However, I would not recommend it because future adoptions will be towards Zscaler, as SSC is a better model than VPN. On a scale of 1-10, I rate this solution a 7.
Santo Joy - PeerSpot reviewer
Head Of Cyber Security at a outsourcing company with 201-500 employees
Security controls have been strengthened with granular application, ringfencing, and access policies
The features of ThreatLocker Zero Trust Endpoint Protection Platform that I like the most are the Ringfencing, elevation control, storage control, and application whitelisting functionality. For examples of how these features benefit my company, we were looking for a solution across various vendors to actually implement application whitelisting controls. ThreatLocker's agent, which is very lightweight and does not use much CPU or RAM, helped us achieve that solution. Ringfencing was an add-on that ticked off a lot of Australian framework security controls, which is the reason we chose it. My impression of the allowlisting feature in terms of managing which software, scripts, and libraries run on my devices is that ThreatLocker's community page has a lot of information around this, which is very helpful. Not only that, the Cyber Hero support that ThreatLocker provides gives us insights and best practices, helping us achieve that solution and guiding us to the right platform. The impact of Ringfencing on controlling the behavior of approved applications has been a big winner for us because it is something that many other platforms do not provide as a functionality. Having that allowed us to identify what applications talk to each other, which is something that many other platforms do not do. The network control feature impacts my ability to manage network traffic across my endpoints and servers. We have not used this widely across all our partners, but wherever required, we use it. It has been an easy solution for those customers to get that control implemented. The elevation feature's role in facilitating just-in-time administrative access for approved applications shows that elevation control helps in many use cases involving remote control platforms, door usage, and security system platforms that require local admins. There are many solutions that provide this functionality, but the licensing cost seems to be expensive, and it also adds another solution into the mix. Rather than doing that, we try to use ThreatLocker Zero Trust Endpoint Protection Platform to achieve that control. Regarding the storage control feature, I have used it. The primary function is USB blocking, which is very widely adopted, and also just locking down and allowing certain users to access certain file locations helps us there. When it comes to enforcing policy-driven access over various storage devices, it depends on the business risk adapted by the companies that we support, but generally the use case is USB and external storage devices where companies know that is a risk, but they do not have appropriate solutions. There are EDR platforms that claim to do this, but ThreatLocker Zero Trust Endpoint Protection Platform does it at an advanced level. My assessment of the efficiency of the real-time threat intelligence and category controls employed by Web Control in blocking malicious and non-compliant sites leads me to think that Web Control is another functionality within ThreatLocker Zero Trust Endpoint Protection Platform that is an add-on on top of the current set. That is another solution that we use based on what is required for the company, but again, that is not widely adapted yet for our partners.
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Top Industries

By visitors reading reviews
Financial Services Firm
13%
Manufacturing Company
9%
Government
7%
Construction Company
6%
Computer Software Company
11%
Financial Services Firm
11%
Manufacturing Company
11%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business28
Midsize Enterprise10
Large Enterprise49
By reviewers
Company SizeCount
Small Business56
Midsize Enterprise14
Large Enterprise13
 

Questions from the Community

What is your experience regarding pricing and costs for Cisco AnyConnect Secure Mobility Client?
Cisco Secure Client (including AnyConnect) is somewhat expensive compared to others such as Fortinet or Palo Alto, which provide free VPN when the firewall is purchased. Palo Alto and Fortinet prov...
What needs improvement with Cisco AnyConnect Secure Mobility Client?
There are no features that I wish Cisco Secure Client (including AnyConnect) had that it does not currently provide. If I could change one thing about it, I would have no changes to suggest.
What is your primary use case for Cisco AnyConnect Secure Mobility Client?
I primarily use Cisco Secure Client (including AnyConnect) for VPN connections and network-related activities. We have Cisco APIs and Cisco VPN that serve as the foundation for our operations. As a...
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
My experience with pricing, setup cost, and licensing for ThreatLocker Zero Trust Platform is that the pricing is reasonable, the cost is fair, and the licensing is not too high.
What needs improvement with ThreatLocker Allowlisting?
I would suggest adding an AI-based policy recommendation feature to ThreatLocker Zero Trust Platform because we have to create every policy manually. If there were a custom AI that could help with ...
What is your primary use case for ThreatLocker Allowlisting?
Our main use case for ThreatLocker Zero Trust Platform is to provide endpoint security and to control each and every application end-to-end that can run on the company's devices, primarily to secur...
 

Also Known As

Cisco AnyConnect Secure Mobility Client
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

MST, Molina Healthcare, Ritchie Bros. Auctioneers, Arup, New South Wales Rural FireService
Information Not Available
Find out what your peers are saying about Cisco Secure Client (including AnyConnect) vs. ThreatLocker Zero Trust Platform and other solutions. Updated: August 2026.
909,725 professionals have used our research since 2012.