BizTalk Server vs MuleSoft Anypoint Platform comparison

Microsoft and Salesforce are both solutions in the Business-to-Business Middleware category. Microsoft is ranked #8 with an average rating of 6.8, while Salesforce is ranked #1 with an average rating of 7.9. Microsoft holds a 4.7% mindshare in BBM, compared to Salesforce’s 9.8% mindshare. Additionally, 75% of Microsoft users are willing to recommend the solution, compared to 92% of Salesforce users who would recommend it.

BizTalk Server

Read 16 BizTalk Server reviews

1,276 Views
574 Comparison Views

75% willing to recommend

MuleSoft Anypoint Platform

Read 60 MuleSoft Anypoint Platform reviews

10,293 Views
1,132 Comparison Views

92% willing to recommend

BizTalk Server

MuleSoft Anypoint Platform

Comparison Buyer's Guide

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Executive SummaryUpdated on Dec 28, 2025

BizTalk Server and MuleSoft Anypoint Platform both compete in the integration platform category. MuleSoft has the upper hand due to its advanced API management, cloud capabilities, and flexibility, despite its higher cost compared to BizTalk, which offers affordability and ease of XML transaction integration.

Features: BizTalk Server offers sophisticated orchestration features, robust Visual Studio integration, and tools like an orchestration debugger and mapper tool. MuleSoft Anypoint Platform provides advanced API management, a wide range of connectors, and visual tools for integration tasks, supporting hybrid cloud deployments.

Room for Improvement: BizTalk Server needs to address performance bottlenecks with high message volumes, outdated technology, and complex debugging and deployment processes. MuleSoft Anypoint Platform could enhance runtime management, improve technical support responsiveness, and simplify its complex pricing model.

Ease of Deployment and Customer Service: BizTalk Server is mainly deployed on-premises, receiving mixed reviews on technical support due to reliance on knowledgeable engineers. MuleSoft Anypoint Platform offers flexible public, private, and hybrid cloud deployment and robust support but faces criticism for its complex pricing model.

Pricing and ROI: BizTalk Server is affordable for larger enterprises but may underwhelm smaller businesses. Its licensing can be costly if not fully utilized. MuleSoft Anypoint Platform is expensive but justifies its cost with extensive features and flexibility in scaling usage, providing higher ROI for complex enterprise needs.

To learn more, read our detailed BizTalk Server vs. MuleSoft Anypoint Platform Report (Updated: December 2025).

Buyer's Guide

BizTalk Server vs. MuleSoft Anypoint Platform

December 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

ROI

Sentiment score

5.8

BizTalk Server offers great ROI for large industries, but smaller businesses might prefer cloud solutions for more flexible options.

Sentiment score

5.5

MuleSoft Anypoint Platform provides ROI through cost efficiency, reduced maintenance expenses, and enabling reuse in enterprises and smaller businesses.

BizTalk Server's ROI is comparatively higher than Boomi and Workato.

reviewer2759421

Service Owner at a logistics company with 10,001+ employees

Now the direction is to move away from BizTalk Server to IBM WebMethods, which has more features compared to BizTalk Server.

Taqi-Hasan

Senior Application Specialist at Taqa Distribution

For more quotes and insights, download the BizTalk Server report

No quotes available

For more quotes and insights, download the MuleSoft Anypoint Platform report

Customer Service

Sentiment score

4.8

User experiences vary, with praised documentation, competent engineers, and mix of Microsoft's support and external consulting for assistance.

Sentiment score

6.7

MuleSoft Anypoint has highly-rated support with fast response times, though documentation and response times need improvement.

No quotes available

For more quotes and insights, download the BizTalk Server report

I would probably rate the support for MuleSoft Anypoint Platform a nine on a scale from one to ten.

Greg O

Senior Validation Engineer at Weir Group PLC

The support team is responsive and helpful.

PietroDell'Erba

Solutions Architect at a manufacturing company with 10,001+ employees

The Salesforce team offers different levels of support.

Satish Vardhani

Senior Consultant at Radiotechnologies

For more quotes and insights, download the MuleSoft Anypoint Platform report

Scalability Issues

Sentiment score

6.0

BizTalk Server's scalability receives mixed reviews; some find it expandable, others face issues with increasing message volumes.

Sentiment score

7.3

MuleSoft Anypoint Platform offers scalable, flexible solutions for enterprises, though automated scalability and data demands can be limiting.

It is time for low-code, no-code, and a quick go-to-market should be faster.

reviewer2759421

Service Owner at a logistics company with 10,001+ employees

For more quotes and insights, download the BizTalk Server report

MuleSoft Anypoint Platform is quite scalable, and it meets our use cases with no issues preventing implementation.

PietroDell'Erba

Solutions Architect at a manufacturing company with 10,001+ employees

MuleSoft provides the ability to scale, yet it is costly to do so.

reviewer2591856

Integration Lead at a retailer with 10,001+ employees

For more quotes and insights, download the MuleSoft Anypoint Platform report

Stability Issues

Sentiment score

6.8

BizTalk Server is stable but struggles with large data, losing relevance as users increasingly transition to cloud solutions.

Sentiment score

7.7

MuleSoft Anypoint Platform is stable, though users report occasional connector issues and variability in scalability and performance.

BizTalk Server is good for small companies but not for big companies.

Taqi-Hasan

Senior Application Specialist at Taqa Distribution

BizTalk Server's stability rates about eight or nine out of ten.

Dipl.Ing. Johann Pointner

Consultant at EC live! Hans Pointner

For more quotes and insights, download the BizTalk Server report

No quotes available

For more quotes and insights, download the MuleSoft Anypoint Platform report

Room For Improvement

BizTalk Server needs better debugging, deployment, scalability, cloud integration, JSON support, API management, and task management to stay competitive.

MuleSoft users seek faster updates, improved support, better pricing, enhanced UI, and expanded Anypoint MQ and integration capabilities.

BizTalk Server needs improvements, especially because we use it for EDI messaging, and it would be very useful to have enhanced tracking capabilities for message tracking and archiving of messages.

Dipl.Ing. Johann Pointner

Consultant at EC live! Hans Pointner

We initially planned to move to Azure Integration Services, but there are challenges with AIS, so now we are evaluating WebMethods IO.

reviewer2759421

Service Owner at a logistics company with 10,001+ employees

For more quotes and insights, download the BizTalk Server report

MuleSoft is considered expensive, so pricing is a major concern.

reviewer2591856

Integration Lead at a retailer with 10,001+ employees

Currently, it uses other standards, but adopting OpenAPI, the standard in the market, would be beneficial.

PietroDell'Erba

Solutions Architect at a manufacturing company with 10,001+ employees

When dealing with multiple transactions or trading, the system can lose control, and tracking becomes hectic.

Satish Vardhani

Senior Consultant at Radiotechnologies

For more quotes and insights, download the MuleSoft Anypoint Platform report

Setup Cost

BizTalk Server offers flexible deployment but can be costly compared to Azure, with users favoring cloud solutions for efficiency.

MuleSoft Anypoint Platform is costly, best for larger organizations, offering workload reduction but requires careful cost planning.

The only thing I heard is that it's not inexpensive.

Dipl.Ing. Johann Pointner

Consultant at EC live! Hans Pointner

For more quotes and insights, download the BizTalk Server report

I do not know the specific costs, but given that it is part of MuleSoft, I suspect it is not cheap.

PietroDell'Erba

Solutions Architect at a manufacturing company with 10,001+ employees

MuleSoft is considered one of the more expensive products in the market.

reviewer2591856

Integration Lead at a retailer with 10,001+ employees

The platform reduces manual workload in maintaining infrastructure, but it does come with some cost considerations.

Satish Vardhani

Senior Consultant at Radiotechnologies

For more quotes and insights, download the MuleSoft Anypoint Platform report

Valuable Features

BizTalk Server excels in seamless integrations, data processing, and reliability with its workflows, adapters, and low-code configurations.

MuleSoft Anypoint Platform excels in API management, seamless integration, user-friendly design, scalability, and connectivity for hybrid environments.

Boomi has advantages over BizTalk Server because it is more flexible, low-code, no-code, easy to implement, and has a fast go-to-market.

reviewer2759421

Service Owner at a logistics company with 10,001+ employees

BizTalk Server offers workflow functionality that I find very effective for process automation.

Dipl.Ing. Johann Pointner

Consultant at EC live! Hans Pointner

For more quotes and insights, download the BizTalk Server report

The most valuable feature is the full lifecycle management, including Anypoint Designer and Exchange, as well as Discofolio API.

reviewer2591856

Integration Lead at a retailer with 10,001+ employees

MuleSoft Anypoint Platform helps to standardize data integration approaches, making it easier to implement integration projects.

PietroDell'Erba

Solutions Architect at a manufacturing company with 10,001+ employees

The platform is integrated with Salesforce, making it preferable when using Salesforce products.

Satish Vardhani

Senior Consultant at Radiotechnologies

For more quotes and insights, download the MuleSoft Anypoint Platform report

Categories and Ranking

BizTalk Server

Ranking in Business-to-Business Middleware

8th

Average Rating

7.2

Reviews Sentiment

6.1

Number of Reviews

Ranking in other categories

Process Automation (13th)

MuleSoft Anypoint Platform

Ranking in Business-to-Business Middleware

1st

Average Rating

8.0

Reviews Sentiment

6.6

Number of Reviews

Ranking in other categories

Message Queue (MQ) Software (4th), Workload Automation (5th), Cloud Data Integration (4th), Integration Platform as a Service (iPaaS) (2nd)

Mindshare comparison

As of December 2025, in the Business-to-Business Middleware category, the mindshare of BizTalk Server is 4.7%, up from 3.6% compared to the previous year. The mindshare of MuleSoft Anypoint Platform is 9.8%, down from 13.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Business-to-Business Middleware Market Share Distribution
Product	Market Share (%)
MuleSoft Anypoint Platform	9.8%
BizTalk Server	4.7%
Other	85.5%

Business-to-Business Middleware

Featured Reviews

Taqi-Hasan

Senior Application Specialist at Taqa Distribution

Offers valuable integration services but requires better cloud adaptation

Biztalk server doesn't have API management so that our exposed can be protected against the SQL injection, DOS attacks. However, this is available in IBM WebMethods. The positive impact of BizTalk Server was initially limited because of scalability issues. That is the reason why management has decided to implement IBM WebMethods. We are going to decommission BizTalk Server next year. I believe the API response could be improved in BizTalk Server. We need to increase the number of servers in BizTalk Server. We used to have two servers; later on, we increased to a third server, which has improved performance. We can make it more highly available and scale out to improve BizTalk Server. Scale out means we can increase the number of servers horizontally.

Read full review

Greg O

Senior Validation Engineer at Weir Group PLC

Integration workflows have become transparent and secure while error tracking is streamlined

The best features in MuleSoft Anypoint Platform for me are transparency between logging in or deploying and using different environments. Managing different environments for the transparency of error logins or how to trace traceability is very important. It's very easy to use and sort, so you can see where everything has gone right and everything has gone wrong. I'm aware of the drag-and-drop interface in MuleSoft Anypoint Platform, and it's very, very quick. It's very time-saving and very efficient. The security features on MuleSoft Anypoint Platform help maintain data integrity in my organization; I would say it's second to none. It's one of the best out there that I have worked with because of the encryption and decryption, and there are a lot of security aspects. I would assess the platform's data mapping and transformation capabilities as amazing. Automation has been straightforward; the transformation and mapping have been easy to use, easy to source, and from the source to the target. I would say it has been very good.

Read full review

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Top Industries

By visitors reading reviews

Financial Services Firm

14%

Manufacturing Company

13%

Computer Software Company

11%

Healthcare Company

Financial Services Firm

12%

Manufacturing Company

11%

Computer Software Company

11%

Government

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	7
Large Enterprise	9

By reviewers
Company Size	Count
Small Business	22
Midsize Enterprise	12
Large Enterprise	30

Questions from the Community

What do you like most about BizTalk Server?

The tool's most valuable feature is its integration with the banks. Its messaging and routing capabilities are good.

See all answers

What needs improvement with BizTalk Server?

I am generally satisfied with BizTalk Server, but there are some gaps, as we have multiple integration tools. Thus, there is associated cost, operation cost, license cost, and CapEx, so we are tryi...

See all answers

What advice do you have for others considering BizTalk Server?

I have not worked with Amazon API Gateway or Mule ESB; I am just testing them. I am using Boomi iPaaS and WebMethods. I did not purchase it on AWS Marketplace; those are product API systems, and in...

See all answers

What advice do you have for others considering Mule Anypoint Platform?

I architected solutions using Oracle SOA/OSB, Spring Boot, MuleSoft Anypoint Platform on cloud / on-premises and hybrid modes; What I see is though if you are an enterprise and have enough money th...

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How does TIBCO BusinessWorks compare with Mule Anypoint Platform?

Our organization ran comparison tests to determine whether TIBCO BusinessWorks or Mule Anypoint platform integration and connectivity software was the better fit for us. We decided to go with Mule...

See all answers

What can Mule Anypoint Platform be used for and what do you use it for most often?

This is a very flexible solution that comes with multiple uses. My organization mostly uses Mule Anypoint Platform for API management, as it lets us build new APIs easily and design new interfaces...

See all answers

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Boomi iPaaS vs MuleSoft Anypoint Platform

Compared 3% of the time

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Product Reports

Buyer's Guide

BizTalk Server

December 2025

Download BizTalk Server product report

Buyer's Guide

MuleSoft Anypoint Platform

December 2025

Download MuleSoft Anypoint Platform product report

Also Known As

No data available

Data Integrator, Anypoint MQ

Overview

Connects systems both inside and across organizations, exchange data and orchestrate business processes across multiple systems.

Microsoft

MuleSoft Anypoint Platform provides API management and integration capabilities with scalability, ensuring seamless connectivity across systems.

MuleSoft Anypoint Platform offers API management and integration capabilities within a user-friendly interface. With a range of connectors and the ability to handle integration patterns, it enables data integration across environments with support for API-led connectivity. High scalability, observability, batch processing, and tooling are key features, enhancing performance while simplifying deployment.

What are the standout features of MuleSoft Anypoint Platform?

API Management: Comprehensive tools for managing APIs effectively.
Integration Capabilities: Facilitates diverse integration patterns.
Connectors: Extensive library for connecting various systems.
Observability: Enhances monitoring and performance tracking.
Batch Processing: Manages large volumes of data efficiently.

What benefits and ROI should users expect?

Scalability: Adaptable to growing data demands across platforms.
Performance: Simplifies complex deployments and improves processing.
Flexibility: Supports multiple environments, from cloud to on-premises.
User-Friendly: Streamlines integration processes with robust tools.

MuleSoft Anypoint Platform is employed by organizations for API management and seamless integration across systems in industries like retail and e-commerce. It connects enterprise applications in environments such as SAP and Salesforce. Users leverage it for data transformation and synchronization, achieving efficient real-time processing and a middleware layer across systems.

Salesforce

Sample Customers

Centrebet, Seoul National University Bundang Hospital, QualCare, Wªrth Handelsges.m.b.H, DTEK, Allscripts, United BioSource, Hogg Robinson

VMware, Gucci, MasterCard, Target, Time Inc, Hershey's, Tesla, Spotify, Office Depot, Intuit, CBS, Amtrak, Salesforce, Gap, Ralph Lauren

Buyer's Guide

BizTalk Server vs. MuleSoft Anypoint Platform

December 2025

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