

Microsoft Defender for Office 365 and ThreatLocker Zero Trust Endpoint Protection Platform compete in cybersecurity solutions for business environments. Defender for Office 365 offers strong email security, while ThreatLocker excels in granular application control, giving it an advantage in environments emphasizing zero trust and application monitoring.
Features: Microsoft Defender for Office 365 delivers robust email security through features like safe attachments, safe links, and anti-phishing capabilities. It integrates seamlessly with Microsoft applications, enhancing threat detection and response. Additionally, it offers thorough data loss prevention across Office 365 applications. ThreatLocker provides strong application control using allowlisting and zero trust strategies, allowing for strict policy-based software approval. Its learning mode and ease of integration enhance security with minimal manual oversight. ThreatLocker also delivers visibility into user actions and application usage, essential for effective monitoring and management.
Room for Improvement: Microsoft Defender for Office 365 needs better cross-platform compatibility and integration with non-Microsoft solutions. Improvements in user-friendly alerts and notifications are needed, along with clearer licensing models. ThreatLocker should improve software deployment efficiency to avoid network saturation and enhance support ticket management. Integrating a VirusTotal score for files and refining the user interface would further boost usability.
Ease of Deployment and Customer Service: Microsoft Defender for Office 365 is compatible with various cloud deployments but struggles with complex documentation and inconsistent support response times. Technical support experiences differ based on agreements. ThreatLocker offers quick deployment across cloud and on-premises setups and provides excellent support despite occasional network issues during policy updates.
Pricing and ROI: Microsoft Defender for Office 365 is bundled with Office 365, leading to a complex cost structure. Although competitively priced, it might be high for smaller entities. ThreatLocker, on the other hand, offers clarity and flexibility in its pricing model, appreciated for its reasonable cost relative to features. ThreatLocker provides better pricing transparency and flexibility, whereas Defender's pricing complexities could pose challenges for some customers.
It has also decreased our time to detection and response by about 15 to 20 percent.
Overall, cost of owning and operating our system goes down.
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
The main return on investment is peace of mind, knowing that with ThreatLocker on any endpoint, it will almost always block all malicious code or exploits, even zero-day exploits.
It keeps malware, Trojans, and ransomware at bay.
Over the past two years, there have been no critical problems.
we opened tickets, and they typically resolve them quickly.
Customer service and support have been fantastic.
They have been very responsive, helpful, and knowledgeable.
I would rate their customer support a ten out of ten.
Their support is world-class.
We have never faced scalability problems, and Microsoft manages it effectively.
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
I would rate it a ten out of ten for scalability.
The solution is stable, as we have been using it for the past two years.
I would assess the stability and reliability of Microsoft Defender for Office 365 as very stable, with barely any issues.
Overall, the stability and reliability of Microsoft Defender for Office 365 are good.
For five years, we have not had a problem.
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
It has been very stable, reliable, and accessible.
The main area for improvement is simplifying the implementation and rollout process.
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
There is a different console for different things; I just want one consolidated console.
Controlling the cloud environment, not just endpoints, is crucial.
This is problematic when immediate attention is needed.
Comprehensive 24-hour log monitoring is a valuable enhancement for both business and enterprise-level users.
We've likely saved 30% of costs.
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Microsoft is quite affordable with a lot of features available for any size organization.
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
I had a really good deal at the time, and it continues to be cost-effective.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
It protects our customers.
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.


| Product | Market Share (%) | 
|---|---|
| Microsoft Defender for Office 365 | 7.7% | 
| ThreatLocker Zero Trust Endpoint Protection Platform | 3.1% | 
| Other | 89.2% | 


| Company Size | Count | 
|---|---|
| Small Business | 23 | 
| Midsize Enterprise | 8 | 
| Large Enterprise | 27 | 
| Company Size | Count | 
|---|---|
| Small Business | 32 | 
| Midsize Enterprise | 4 | 
| Large Enterprise | 3 | 









Microsoft Defender for Office 365 is a comprehensive security solution designed to protect organizations against advanced threats in their email, collaboration, and productivity environments. It combines the power of Microsoft's threat intelligence, machine learning, and behavioral analytics to provide real-time protection against phishing, malware, ransomware, and other malicious attacks.
With Microsoft Defender for Office 365, organizations can safeguard their email communication by detecting and blocking malicious links, attachments, and unsafe email content. It employs advanced anti-phishing capabilities to identify and prevent sophisticated phishing attacks that attempt to steal sensitive information or compromise user credentials.
This solution also offers robust protection against malware and ransomware. It leverages machine learning algorithms to analyze email attachments and URLs in real-time, identifying and blocking malicious content before it reaches users' inboxes. Additionally, it provides advanced threat-hunting capabilities, allowing security teams to proactively investigate and respond to potential threats.
Microsoft Defender for Office 365 goes beyond email protection and extends its security features to other collaboration tools like SharePoint, OneDrive, and Teams. It scans files and documents stored in these platforms, ensuring that they are free from malware and other malicious content. It also provides visibility into user activities, helping organizations detect and mitigate insider threats.
Furthermore, this solution offers rich reporting and analytics capabilities, providing organizations with insights into their security posture and threat landscape. It enables security administrators to monitor and manage security incidents, track trends, and take proactive measures to enhance their overall security posture.
ThreatLocker Zero Trust Endpoint Protection Platform offers robust endpoint security through application control and allowlisting, safeguarding servers and workstations from unauthorized software execution.
ThreatLocker Zero Trust Endpoint Protection Platform provides extensive application control with features like ring-fencing and selective elevation, ensuring meticulous execution management. Offering learning mode and extensive support, it integrates threat detection and activity monitoring to enhance compliance, reduce costs, and bolster cybersecurity through alerts and approvals. Despite its strengths, there are areas for improvement in training flexibility, policy updates, and interface enhancements, along with challenges in handling non-digitally signed software. Deployed across environments, it works well with existing cybersecurity instruments for real-time threat prevention.
What are the top features of ThreatLocker?ThreatLocker Zero Trust Endpoint Protection Platform is widely implemented to safeguard IT infrastructures against unauthorized access and application use. In sectors where data security is paramount, this platform enables users to prevent unauthorized software installations and control device applications, ensuring real-time threat prevention and compliance with industry regulations.
We monitor all Advanced Threat Protection (ATP) reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.