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Microsoft Defender for Endpoint vs VirusTotal comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Anti-Malware Tools
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
197
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Advanced Threat Protection (ATP) (4th), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (4th)
VirusTotal
Ranking in Anti-Malware Tools
3rd
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
11
Ranking in other categories
Threat Intelligence Platforms (3rd)
 

Mindshare comparison

As of July 2025, in the Anti-Malware Tools category, the mindshare of Microsoft Defender for Endpoint is 15.6%, down from 21.0% compared to the previous year. The mindshare of VirusTotal is 5.1%, down from 6.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Anti-Malware Tools
 

Featured Reviews

Sudhen Swami - PeerSpot reviewer
Easy to update with good protection and a useful cloud portal
We've mainly used it for endpoints. However, we've also used it for DLP as well. We're also in the process of implementing it for cloud and identity as well. However, it's very good for endpoints, and that's our main focus. The malware protection is good. The visibility it provides is very useful. We can combine visibility with wider security features and alerts around malware, misconfiguration, or any other kinds of threats. The cloud portal is quite good. From there, we are able to see alerts and have colleagues review issues and monitor to see if any patterns arise. It's serving us quite well overall. It allows us to look at other items, like application and browser control. It helps us prioritize threats. We have a process in place now where we can review issues and remediate them effectively. We have been able to integrate a variety of Microsoft security products together. We use Azure AD, for example, and we've begun to implement DLP, among other items. We're looking at labeling and tagging and will expand into that soon. Defender has more stringent system requirements than, for example, Check Point. So when we implemented the Check Point Endpoint agent, that solution didn't mind what version of Windows you were using. When we moved to Defender, Defender had certain system prerequisites that had to be met. So we had to make sure that we're on a minimum version of Windows when we're utilizing Office, and Office has to be a particular version as well. It has more stringent system requirements that have to be met before you can implement it. It works natively together with other Microsoft solutions. Once you get more and more of those different components across the environment, then you start to get better visibility. So, rather than having lots of different solutions, you have fewer solutions and a single vendor solution. That way, you start getting into a position where you get better visibility and integration as well. The standardization is good. It's important. It's helping me with monitoring and learning. Updates and upgrades are quite smooth and seamless. Defender helps us automate routine tasks. Quite a lot of Microsoft is straightforward for us now. Previously, we didn't have enough resources and were unable to look at the alerts. Having this in place makes things a lot more straightforward for us. We have both the technology and the people in place now, alongside the process. We do see the benefits in that, and that's why we're continuing our adoption across the estate in terms of client and server as well. It's helping us avoid looking at multiple dashboards and centralized monitoring. We're not fully there yet. We're getting there. While we haven't witnessed time saving yet, once it's fully deployed, it will. By then, we'll have standardized processes across a single solution. We have saved money, however, as we continue to reduce non-Mircosft systems. Since we won't be using various competing technologies, we can save on licensing costs. We've likely so far saved 15%. While it's hard to estimate exactly how much, the solution has helped us decrease time to detection and time to respond.
Chinmay Banerjee - PeerSpot reviewer
Helps businesses collect threat data while keeping privacy in mind and apable of detecting, blocking, and removing viruses and malware
There are two gray areas I still need to explore. I have worked with VirusTotal because it easily integrates with over seventy antivirus scanners and blacklisting services. In addition to those there is much scope to improve and add other services or integrations. The areas for improvement are that VirusTotal is not using much AI or generative AI models, while other competitors are starting to build them. For example, VirusTotal's work is based on the setup done by their engineers. If you want to do scanning or protection activities for a specific site, app, or device, that is the area VirusTotal is currently focused on. But other competitors are building AI models that can do things like left-side scanning and provide auto-generated reports. VirusTotal has predefined reports, but there is a lot of manual effort involved. Secondly, the API is very limited if I want to integrate VirusTotal with other applications. They need to build more connectors and provide support for Webhook connectors for the API. If you can't build your own connector, it's always good to have provisions for Webhook setup connectors across platforms. Thirdly, Kaspersky, a competitor of VirusTotal, is using a methodology called "gatekeeper." A gatekeeper is a security system that protects the inside of a building from outside threats. This is the model Kaspersky is currently using. You have your website set up, but the entire army of VirusTotal or Kaspersky is standing guard, protecting you from the first gate itself. Right now, VirusTotal detects threats from your domain, but it is always better to verify inside the domain and protect it from the first level when people or malware are entering. This first level of protection is lacking in VirusTotal right now. The security bridge and protection gate are missing.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The technical support from Microsoft is very good. We are part of the Microsoft Suite, and from being part of this we have consistent news regarding Microsoft Defender for Endpoint."
"It is stable and easy to use. Everything is okay, and there are no performance issues."
"The protection that it provides is quite good."
"This solution definitely increases our security posture. When you are reviewing your existing fleet or endpoints and based on the configuration that you put out of your Defender for Endpoint, you then receive a security score from Microsoft. Depending on what rules you have configured, what policies you have deployed, and what attack surface reduction rules that you have set up and deployed, it is almost gamifying information security in the sense that you are always trying to achieve a higher score. The more hardening you perform on your endpoints, the better score you receive. This generally tends to give you a better peace of mind, but also makes you secure at the same time."
"You have endpoint security to keep your devices safe. That's the feature that we're interested in."
"Microsoft Defender for Endpoint is easy to load and it runs quietly in the background, unlike other solutions."
"Defender is stable enough and is competitive with the other products in the market."
"I've started to test it from the security point of view. There are plenty of features that are interesting, but at this time, the XDR functionality is most valuable. It is endpoint security on steroids."
"It is quite simple for anyone if they just want to check some suspicious URLs."
"It can scan the dark web and find if an email ID has been compromised. This is another area that we have not explored yet."
"The initial setup is easy."
"The feature I like the most is the ability to see the MD5 or SHA-256 signature of the file, and also the composition of the file according to its segments."
"The most valuable feature is the worldwide malware information database."
"The product is easy to use with coding, such as Python or Java, via its API."
"VirusTotal provides 95% to 98% accurate information."
"It provides detailed insights into possible malicious behavior, dropped files, and TCP connections."
 

Cons

"We'd like the stability to be better."
"There could be an increase in security for the solution."
"A single dashboard would be a significant improvement."
"Localization is always a challenge, especially with new products you typically want. Solutions are designed to be deployed where the most licenses are being consumed, such as in the United States. They focus on US products, devices, and networks. Specialized deployments for other countries would allow for a smoother experience in transition."
"Sometimes, there are difficulties in downloading a file considered as malicious."
"The onboarding and deployment could be more user-friendly, and there is room to grow in some of the reports. I don't want them to be oversimplified or overly complex, but there is room for improvement in the reporting it can do. It's relatively minor."
"Updates are not coming out of preview quickly enough and it is holding back on the development of the product."
"We encountered some misbehavior between Microsoft Office Suite and Defender. We had issues of old macros being blocked and some stuff going around the usage of Win32 APIs. There is some improvement between the Office products and Defender, and there is a bunch of stuff that you can configure in your antivirus solutions, but you have several baselines, such as security baselines for Edge, security baselines for Defender, and security baselines for MDM. You have configuration profiles as well. So, there a lot of parts where we can configure our antivirus solution, and we're getting conflicting configurations. This is the major part with which we're struggling in this solution. We are having calls and calls with Microsoft for getting rid of all configuration conflicts that we have. That's really the part that needs to be improved."
"VirusTotal has predefined reports, but there is a lot of manual effort involved."
"VirusTotal is hard to understand because you need to know Google Docs to create queries, and it doesn't have documentation for that."
"I would like to see improvements in the score consistency and accuracy."
"There should be room for improvement, particularly in the API side of things."
"They can improve the telemetry. Whenever we handle a sample, they cannot provide any information about a victim."
"VirusTotal has different versions, and sometimes the parameters of the API are not very clear."
"There is room for improvement, particularly in making some of the most useful features more accessible in the non-paid version."
"I would like to see an improved user interface and some automation."
 

Pricing and Cost Advice

"Buying individual point products would've cost us a lot more money than one integrated solution that also capitalizes on Teams Voice and things of that nature. Given our size, buying individual products would have easily cost us a million dollars."
"The price is fair for the features Microsoft delivers. If you want tailor-made features, you have to mix different licenses. It isn't straightforward."
"You just pay Windows 10 prices, then you have antivirus software. As a price comparison, Defender's costs are very low."
"It's all pretty easy. For some clients, it's an easier sell because it's just an add-on to their existing Microsoft licensing and Office 365 licensing."
"The subscription is part of Windows, so we don't have to pay anything extra for this product."
"Microsoft Defender for Endpoint is included with a Microsoft E5 license."
"Microsoft Defender for Endpoint is more affordable compared to some other endpoint solutions."
"For me, the pricing is very good, but for management it's very expensive. Other solutions are less expensive. But when I present all the information and all the reports they say, "Well, it's expensive, but the cost-benefit is very good.""
"The pricing is very economical."
"VirusTotal is an expensive solution."
"We are using VirusTotal with free licenses, managing the license limits across three or four accounts, thus incurring no costs."
"The pricing is reasonable."
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Top Industries

By visitors reading reviews
Computer Software Company
13%
Educational Organization
11%
Financial Services Firm
8%
Government
8%
Computer Software Company
19%
Financial Services Firm
8%
Government
8%
University
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about VirusTotal?
With VirusTotal, I can check for any hash, malware, file, domain, IP URL, or malicious URL, and Kaspersky stays clean.
What is your experience regarding pricing and costs for VirusTotal?
I do not know about the pricing or licensing as our organization services VirusTotal for our clients.
What needs improvement with VirusTotal?
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the categ...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Information Not Available
Find out what your peers are saying about Microsoft Defender for Endpoint vs. VirusTotal and other solutions. Updated: June 2025.
861,390 professionals have used our research since 2012.