Try our new research platform with insights from 80,000+ expert users

Microsoft Defender for Endpoint vs VirusTotal comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Anti-Malware Tools
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
197
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Advanced Threat Protection (ATP) (4th), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (6th)
VirusTotal
Ranking in Anti-Malware Tools
3rd
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
11
Ranking in other categories
Threat Intelligence Platforms (3rd)
 

Mindshare comparison

As of June 2025, in the Anti-Malware Tools category, the mindshare of Microsoft Defender for Endpoint is 16.0%, down from 21.7% compared to the previous year. The mindshare of VirusTotal is 5.1%, down from 7.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Anti-Malware Tools
 

Featured Reviews

Sudhen Swami - PeerSpot reviewer
Easy to update with good protection and a useful cloud portal
We've mainly used it for endpoints. However, we've also used it for DLP as well. We're also in the process of implementing it for cloud and identity as well. However, it's very good for endpoints, and that's our main focus. The malware protection is good. The visibility it provides is very useful. We can combine visibility with wider security features and alerts around malware, misconfiguration, or any other kinds of threats. The cloud portal is quite good. From there, we are able to see alerts and have colleagues review issues and monitor to see if any patterns arise. It's serving us quite well overall. It allows us to look at other items, like application and browser control. It helps us prioritize threats. We have a process in place now where we can review issues and remediate them effectively. We have been able to integrate a variety of Microsoft security products together. We use Azure AD, for example, and we've begun to implement DLP, among other items. We're looking at labeling and tagging and will expand into that soon. Defender has more stringent system requirements than, for example, Check Point. So when we implemented the Check Point Endpoint agent, that solution didn't mind what version of Windows you were using. When we moved to Defender, Defender had certain system prerequisites that had to be met. So we had to make sure that we're on a minimum version of Windows when we're utilizing Office, and Office has to be a particular version as well. It has more stringent system requirements that have to be met before you can implement it. It works natively together with other Microsoft solutions. Once you get more and more of those different components across the environment, then you start to get better visibility. So, rather than having lots of different solutions, you have fewer solutions and a single vendor solution. That way, you start getting into a position where you get better visibility and integration as well. The standardization is good. It's important. It's helping me with monitoring and learning. Updates and upgrades are quite smooth and seamless. Defender helps us automate routine tasks. Quite a lot of Microsoft is straightforward for us now. Previously, we didn't have enough resources and were unable to look at the alerts. Having this in place makes things a lot more straightforward for us. We have both the technology and the people in place now, alongside the process. We do see the benefits in that, and that's why we're continuing our adoption across the estate in terms of client and server as well. It's helping us avoid looking at multiple dashboards and centralized monitoring. We're not fully there yet. We're getting there. While we haven't witnessed time saving yet, once it's fully deployed, it will. By then, we'll have standardized processes across a single solution. We have saved money, however, as we continue to reduce non-Mircosft systems. Since we won't be using various competing technologies, we can save on licensing costs. We've likely so far saved 15%. While it's hard to estimate exactly how much, the solution has helped us decrease time to detection and time to respond.
Chinmay Banerjee - PeerSpot reviewer
Helps businesses collect threat data while keeping privacy in mind and apable of detecting, blocking, and removing viruses and malware
There are two gray areas I still need to explore. I have worked with VirusTotal because it easily integrates with over seventy antivirus scanners and blacklisting services. In addition to those there is much scope to improve and add other services or integrations. The areas for improvement are that VirusTotal is not using much AI or generative AI models, while other competitors are starting to build them. For example, VirusTotal's work is based on the setup done by their engineers. If you want to do scanning or protection activities for a specific site, app, or device, that is the area VirusTotal is currently focused on. But other competitors are building AI models that can do things like left-side scanning and provide auto-generated reports. VirusTotal has predefined reports, but there is a lot of manual effort involved. Secondly, the API is very limited if I want to integrate VirusTotal with other applications. They need to build more connectors and provide support for Webhook connectors for the API. If you can't build your own connector, it's always good to have provisions for Webhook setup connectors across platforms. Thirdly, Kaspersky, a competitor of VirusTotal, is using a methodology called "gatekeeper." A gatekeeper is a security system that protects the inside of a building from outside threats. This is the model Kaspersky is currently using. You have your website set up, but the entire army of VirusTotal or Kaspersky is standing guard, protecting you from the first gate itself. Right now, VirusTotal detects threats from your domain, but it is always better to verify inside the domain and protect it from the first level when people or malware are entering. This first level of protection is lacking in VirusTotal right now. The security bridge and protection gate are missing.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable aspect lies in its automation capabilities, particularly within security automation."
"Defender works in the background monitoring the traffic for viruses."
"The primary advantage is that you don't need to install it. It's included in the Windows 10 delivery."
"This is a very go, proactive solution to threat protection using advanced analysis."
"The most valuable feature is that it comes with the package, so there is no additional installation of third-party software. It's also easy to use."
"The fact that it's from Microsoft, you don't have many false positives, unlike products from other vendors might have."
"Defender is stable. The performance is good."
"Its simplicity is the most valuable. It also has very good integration. We like it."
"The most valuable feature is the worldwide malware information database."
"It provides detailed insights into possible malicious behavior, dropped files, and TCP connections."
"VirusTotal provides 95% to 98% accurate information."
"VirusTotal provides 95% to 98% accurate information."
"It allows us to see if there have been previous reports on certain indicators of compromise, providing insights from other security professionals."
"The feature I like the most is the ability to see the MD5 or SHA-256 signature of the file, and also the composition of the file according to its segments."
"It gives detailed information about suspicious IPs, which is one of its most valuable features."
"It is quite simple for anyone if they just want to check some suspicious URLs."
 

Cons

"There could be an increase in security for the solution."
"On the Mac OS platform, there is no parity between Windows and Mac OS. The solution is very feature-rich and very well-integrated into Windows, and I guess baked into Windows 10 and Windows 11. Whereas, on the Mac OS platform, there is still some work there to give it a more feature-reach platform."
"The pricing could be a bit better."
"The price, in general, could always be a little bit cheaper."
"The file scanning has room for improvement. Many people use macros within their files, so there should be a mechanism that helps us to scan them for malicious payloads."
"Sometimes the software doesn't work the way we expect it to, and in those cases, we can't communicate with a device because it may be infected."
"We encountered some issues when we were trying to enable automatic updates from our group policy."
"Cortex... has good investigation capabilities, out-of-the-box, in case there is an event that you'd like to investigate. It's quite convenient. Microsoft has those capabilities as well, but you need a bit more training on the product to get the basic information that you can get out-of-the-box with Cortex."
"I would like to see improved correlation with other threat intelligence sources, not just reliant on its own database, to enhance the database of threat intelligence that VirusTotal offers."
"The platform could improve in the areas of endpoints and networks."
"There is room for improvement, particularly in making some of the most useful features more accessible in the non-paid version."
"VirusTotal is hard to understand because you need to know Google Docs to create queries, and it doesn't have documentation for that."
"VirusTotal needs better advertisement and promotion, especially in the Middle East, since it is not yet widely recognized or popular in that region."
"They can improve the telemetry. Whenever we handle a sample, they cannot provide any information about a victim."
"VirusTotal has predefined reports, but there is a lot of manual effort involved."
"VirusTotal has different versions, and sometimes the parameters of the API are not very clear."
 

Pricing and Cost Advice

"This solution is part of Windows and comes included with it."
"The base price for an E5 license, which includes Enterprise Mobility + Security E5, is $57 per user per month."
"For most people, the price of the license is not something that they have to worry about."
"The subscription is part of Windows, so we don't have to pay anything extra for this product."
"Microsoft Defender is an expensive product in my country."
"Its price at the moment is very good because you get a lot of value for your money, especially with the subscriptions. If you have the E1, E3, or E5 enterprise subscription, you pay per month per user, and you get almost an infinite number of solutions. If you compare the price to the number of solutions that you get, it is a very good deal."
"The solution comes free with Microsoft Windows 10."
"If we are acquiring everything in a single place, the front end becomes cost-effective."
"The pricing is very economical."
"VirusTotal is an expensive solution."
"The pricing is reasonable."
"We are using VirusTotal with free licenses, managing the license limits across three or four accounts, thus incurring no costs."
report
Use our free recommendation engine to learn which Anti-Malware Tools solutions are best for your needs.
856,873 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Educational Organization
19%
Computer Software Company
12%
Government
7%
Financial Services Firm
7%
Computer Software Company
18%
Financial Services Firm
9%
Government
8%
University
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about VirusTotal?
With VirusTotal, I can check for any hash, malware, file, domain, IP URL, or malicious URL, and Kaspersky stays clean.
What is your experience regarding pricing and costs for VirusTotal?
I do not know about the pricing or licensing as our organization services VirusTotal for our clients.
What needs improvement with VirusTotal?
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the categ...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Information Not Available
Find out what your peers are saying about Microsoft Defender for Endpoint vs. VirusTotal and other solutions. Updated: June 2025.
856,873 professionals have used our research since 2012.