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Microsoft Defender for Cloud Apps vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 23, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.7
Microsoft Defender for Cloud Apps increases ROI with enhanced security, cost efficiency, seamless integration, and proactive application monitoring.
Sentiment score
8.1
ThreatLocker Zero Trust Platform enhances security, improves efficiency, saves costs, increases revenue, and supports business growth by reducing threats.
The biggest return on investment so far has been visibility, knowing what we have in our environment.
As a small team, Microsoft Defender for Cloud Apps allowed us to manage systems with just one or two people.
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
The main return on investment is peace of mind, knowing that with ThreatLocker on any endpoint, it will almost always block all malicious code or exploits, even zero-day exploits.
It keeps malware, Trojans, and ransomware at bay.
 

Customer Service

Sentiment score
7.2
Microsoft Defender for Cloud Apps support is knowledgeable but inconsistent, with delays and first-level engineers lacking problem-solving skills.
Sentiment score
8.8
ThreatLocker Zero Trust's responsive customer service, highlighted by the Cyber Hero program, is praised for speed, professionalism, and effectiveness.
Their customer service is pretty good, but it's frustrating to go through three or four channels before reaching the right person.
The support is excellent, and the speed of response is commendable.
There were instances where the engineers were knowledgeable and helpful, but at other times it felt like a ping pong game, with unnecessary transfers until the right person was found.
They have been very responsive, helpful, and knowledgeable.
I would rate their customer support a ten out of ten.
Their support is world-class.
 

Scalability Issues

Sentiment score
8.0
Microsoft Defender for Cloud Apps offers excellent scalability and integration, enhancing security and interoperability in diverse corporate environments.
Sentiment score
8.2
ThreatLocker Zero Trust Platform offers seamless scalability and adaptability, efficiently managing diverse environments and dynamic growth across endpoints.
For what I know about the log collector and how much data it can take in, it is super scalable and capable of handling high workloads.
Microsoft Defender for Cloud Apps is very scalable, provided you have the right subscription.
In my experience, Microsoft Defender for Cloud Apps is good enough for small to medium businesses.
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
I would rate it a ten out of ten for scalability.
 

Stability Issues

Sentiment score
8.1
Microsoft Defender for Cloud Apps is praised for stability, reliability, minimal downtime, and user satisfaction despite rare external issues.
Sentiment score
7.5
ThreatLocker Zero Trust Platform is praised for stability and reliability, with minor issues swiftly addressed by support.
I would rate it a ten because I have not experienced any stability issues so far with Defender for Cloud Apps.
Like any other Microsoft product, the uptime is good.
The current stability of Microsoft Defender for Cloud Apps is quite good.
For five years, we have not had a problem.
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
It has been very stable, reliable, and accessible.
 

Room For Improvement

Microsoft Defender for Cloud Apps requires better integration, user-friendliness, pricing, and improved features like reporting, support, and threat detection.
ThreatLocker needs UI improvements, better integrations, expanded training, enhanced analytics, restricted Learning Mode, and faster support.
For data loss prevention, it would be useful to be able to drill down into the kind of data being transferred over CloudApp.
A significant improvement I would like to see is the integration into a single pane of glass.
Specifically, integration with CASB for on-premise and cloud did not work as anticipated back in 2019.
Controlling the cloud environment, not just endpoints, is crucial.
This is problematic when immediate attention is needed.
Comprehensive 24-hour log monitoring is a valuable enhancement for both business and enterprise-level users.
 

Setup Cost

Microsoft Defender for Cloud Apps is cost-effective and competitive due to integration with Microsoft 365, despite pricing concerns.
Enterprise buyers find ThreatLocker's pricing competitive and flexible, valuing its affordability, transparency, and accessible setup costs.
The pricing for Microsoft Defender for Cloud Apps is acceptable.
My organization is currently revisiting pricing, but previously, the cost was a bit expensive, yet comparable to other solutions with similar functionalities and features.
It's not the cheapest, but also not the most expensive, placing it in the mid-level range.
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
I had a really good deal at the time, and it continues to be cost-effective.
 

Valuable Features

Microsoft Defender for Cloud Apps offers seamless integration, real-time threat detection, and enhanced security monitoring across platforms and applications.
ThreatLocker Zero Trust Platform enhances security with features like application control, selective elevation, and robust network access controls.
The ability to sanction unsanctioned apps using Secure Score benchmarking, included in Cloud, is also beneficial.
Microsoft Defender for Cloud Apps is very comprehensive, providing a complete 360-degree view of applications within an organization.
The most valuable features of Microsoft Defender for Cloud Apps include live, up-to-date information, which provided real-time alerts.
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
It protects our customers.
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.
 

Categories and Ranking

Microsoft Defender for Clou...
Ranking in Advanced Threat Protection (ATP)
12th
Average Rating
8.4
Reviews Sentiment
7.3
Number of Reviews
37
Ranking in other categories
Cloud Access Security Brokers (CASB) (5th), Microsoft Security Suite (13th)
ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
6th
Average Rating
9.2
Reviews Sentiment
7.6
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (6th), Application Control (2nd), ZTNA (3rd), Ransomware Protection (3rd)
 

Mindshare comparison

As of May 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Cloud Apps is 1.6%, up from 1.3% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.9%, up from 1.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Jagadeesh Gunasekaran - PeerSpot reviewer
Saves us time, has good visibility, and a single dashboard
The solution is user-friendly and provides great visibility into threats. There are easy options available for specific workflow inspections. We can also get support by going through the Microsoft documentation, which is straightforward. Microsoft Defender for Cloud Apps helps us prioritize threats across our enterprise. It covers us from a compliance perspective and protects our organization's data. Data protection is a very important aspect of any new organization, as we need to protect our data from both external attacks and insider threats. Microsoft Defender for Cloud Apps helps us monitor for abnormal activity by insiders, which is one of the most important access points for attackers today. Additionally, the different cloud apps that Defender for Cloud Apps supports provide us with much more visibility into potential threats and activities on the internet. We have integrated Microsoft Defender for Cloud Apps alerts with Sentinel. The integration is straightforward. We can find the configuration details on Microsoft's official documentation website. If we are familiar with how Microsoft products work, we will be able to follow the instructions clearly. Microsoft Defender for Cloud Apps and Sentinel work natively together to deliver coordinated detection and response across our environment. Our integrated Microsoft solutions provide comprehensive threat protection, covering most of the tactics and techniques relevant to the MITRE ATT&CK framework. Sentinel allows us to ingest data from our entire ecosystem. When implementing an SIEM solution, there are always prerequisites such as Active Directory logs, security logs, firewall logs, and DNS logs. These are important logs that need to be ingested into the environment. Sentinel has many third-party connectors available that make integrations straightforward. Microsoft provides the configuration details in the Sentinel platform. It is important to integrate all relevant log sources into the SIEM solution so that we can detect and be alerted to any type of threat factor, whether it is from an internal or external source. Integrating third-party solutions into the platform requires a separate configuration, but Microsoft provides the necessary information. However, we need to have the appropriate permissions to execute these setups. Sentinel provides a centralized dashboard that covers threat management and configuration. It gives us complete insight into what entities are accessing, as well as full details for investigation. We can see how the alerts and threats are relevant to suspicious activities, whether they are related to malicious IP addresses, suspicious ASHAs, or any other indicators of compromise. All of this relevant data can be seen in a single pane. Recently, Microsoft introduced a new investigation experience in a single pane. This means that we can now get a lot of details in a single pane, without having to go there and execute a query. There are a lot of new insights being developed in the Sentinel platform these days. It has software intelligence. They recently introduced Microsoft Defender Threat Intelligence, which covers almost all IOCs. This protects organizational assets from threats and suspicious traffic associated with IOCs. If a match is found, alerts are generated. This is a very interesting feature. Another great feature is automation and logic apps. We can create a number of operations, such as posting in a team's channel if a severe incident occurs or sending an email notification. There are many operations available, so we can automate a lot of tasks. Microsoft Defender for Cloud Apps helps us stay compliant. It has predefined mechanisms in place to prevent attacks. For example, if an external user tries to access our SharePoint folders or files, an attack will be blocked. This is why it is important to give appropriate access to guest users. Microsoft Defender for Cloud Apps has many features and benefits. It provides a number of policies that can be configured to meet the specific needs of our security team. These policies can be used to customize cloud applications so that only authorized users can access them and perform operations that benefit the organization. In terms of safety and security, Microsoft Defender for Cloud Apps is top-notch. Using the solution's automation features, we can suppress false positive alerts. We can also close alerts, lower their severity from "high" to "low" or "informational," or close them immediately with the appropriate commands. This will depend on the configuration automation rule and the perspective from which we are testing. Microsoft Defender for Cloud Apps provides a single console. We are also provided with Microsoft templates to enable workbooks instantly. Alternatively, we can build our own customized workbooks to provide better insights and improve our SOC efficiency and overall performance. Consolidating all of our security data into one dashboard has saved our security operations team a significant amount of time. From an analyst's perspective, it is now much easier to correlate events, investigate alerts, and visualize specific entities. For example, an analyst can quickly see all of the alerts associated with a particular IP address, or they can view all of the activity for a specific entity over the past 24 hours or 7 days. This level of detail and insight would not be possible if our data were siloed in multiple dashboards. The single dashboard saves our operations approximately 20 hours per week by eliminating the need to access multiple consoles and tabs. Microsoft Defender for Cloud Apps threat intelligence can help us prepare for potential threats before they happen. However, it depends on how we develop the policies for the database to block or ignore things in our environment.
Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
12%
Manufacturing Company
8%
Government
7%
Computer Software Company
36%
Retailer
8%
Financial Services Firm
5%
Manufacturing Company
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

Which is the better security solution - Cisco Umbrella or Microsoft Cloud App Security?
Cisco Umbrella is an integral component of the Cisco SASE architecture. It integrates security in a single, cloud-native solution, unifying multiple features like DNS-layer security, threat intelli...
What do you like most about Microsoft Cloud App Security?
It does a great job of monitoring and maintaining a security baseline. For us, that is a key element. The notifications are pretty good.
What is your experience regarding pricing and costs for Microsoft Cloud App Security?
The pricing for Microsoft Defender for Cloud Apps is acceptable. If a product is of high quality, it justifies the expense.
What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...
 

Also Known As

MS Cloud App Security, Microsoft Cloud App Security
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

Customers for Microsoft Defender for Cloud Apps include Accenture, St. Luke’s University Health Network, Ansell, and Nakilat.
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Find out what your peers are saying about Microsoft Defender for Cloud Apps vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: April 2025.
850,028 professionals have used our research since 2012.