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Cisco Secure Email Threat Defense vs Vade for M365 comparison

 

Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
27th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Vade for M365
Ranking in Email Security
40th
Average Rating
0.0
Reviews Sentiment
7.4
Number of Reviews
1
Ranking in other categories
Office 365 Protection (9th)
 

Mindshare comparison

As of November 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 0.9% compared to the previous year. The mindshare of Vade for M365 is 0.8%, down from 0.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Cisco Secure Email Threat Defense1.1%
Vade for M3650.8%
Other98.1%
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Bruno Rolland - PeerSpot reviewer
A stable tool capable of detecting malware while focusing on anti-phishing to protect its users
I don't see ISO 27001 in the solution. While working on the solution, sometimes a customer needs to have a conformity level of SOC 1 or SOC 2 or some other conformity level. I did not see the aforementioned conformity levels added to the solution. Concerning a bank, data can be confidential, and when a bank needs to transfer such data, it has to be specific to a certain level of conformity, which I did not see in the product. Vade needs to incorporate the aforementioned aspects to improve their solution.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I highly recommend it as one of the best choices."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Secure Email Threat Defense's scalability is good."
"It's very easy to deploy and configure."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"This solution is easy to use."
"It is a stable solution...My company has no worries about the deployment phase of Vade for Office 365."
 

Cons

"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"This solution could be improved by integration with Sandbox."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"We encounter issues while searching for missing emails."
"Concerning a bank, data can be confidential, and when a bank needs to transfer such data, it has to be specific to a certain level of conformity, which I did not see in the product."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"Vade for Office 365 is a solution offered at competitive prices in the market...Payment has to be made for the whole bundle of Vade products."
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Top Industries

By visitors reading reviews
Computer Software Company
18%
Healthcare Company
8%
Manufacturing Company
7%
Marketing Services Firm
7%
Computer Software Company
18%
Comms Service Provider
14%
Insurance Company
11%
Manufacturing Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
No data available
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
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Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Vade for Office 365, Vade Secure Office 365
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
HTG 360, Weida IT Solutions, KVC Health Systems
Find out what your peers are saying about Microsoft, Abnormal AI, Proofpoint and others in Email Security. Updated: November 2025.
873,003 professionals have used our research since 2012.