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Cisco Secure Email Threat Defense vs Cloudflare One comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jun 22, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
Cloudflare One
Ranking in Email Security
12th
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
20
Ranking in other categories
Secure Web Gateways (SWG) (9th), Data Loss Prevention (DLP) (7th), Cloud Access Security Brokers (CASB) (8th), Distributed Denial-of-Service (DDoS) Protection (5th), Access Management (5th), Bot Management (3rd), ZTNA as a Service (5th), ZTNA (1st), Secure Access Service Edge (SASE) (7th), Remote Browser Isolation (RBI) (2nd)
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of Cloudflare One is 1.5%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Carlos Alam Hernandez Baruch - PeerSpot reviewer
The solution enables seamless security management and fosters a learning environment
Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions. For the solution stopping us for e-learning, I appreciate the concept yet need more resources or courses in Mexico, preferably in Spanish. Certifications are easy, however, I require more real-world environments and instructors.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"The initial setup was easy."
"My experience deploying Microsoft Defender for Office 365 was seamless."
"Scalability-wise, I do not think there are any issues so far."
"Microsoft Defender for Office 365 has improved my organization's security. It makes it easier to manage the infrastructure without the help of third-party applications."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"It's very easy to deploy and configure."
"The product offers protection, email security, anti-spam, and antivirus."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"It has an efficient email filtering feature."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"This solution is easy to understand and easy to configure."
"The blocking feature is very good."
"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"Cloudflare is by far the most effective solution that I have come across."
"Cloudflare, in my opinion, was easy to implement."
"The solution has different options that can be used to differentiate DDoS attacks."
 

Cons

"The UI needs to be more user-friendly."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"The custom alerts have to improve a lot."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"The changes to customer service, specifically the new model for support agreements, are not favorable."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"This solution could be improved by integration with Sandbox."
"The solution is a bit expensive."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The pricing could always be better."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"Operating and tuning the product is difficult."
"Lacks a VPN feature to provide a secure connection to the data center."
"Cloudflare DDoS has poor technical support."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"Our customers no longer use Cloudflare because its service is subpar."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
 

Pricing and Cost Advice

"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"The product is expensive."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"The license is expensive because the cost is based on the number of users."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The pricing is normal. Considering its popularity, it's not overpriced."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"The solution is not that expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
29%
Healthcare Company
7%
Government
6%
Manufacturing Company
6%
Computer Software Company
16%
Financial Services Firm
10%
Comms Service Provider
10%
Manufacturing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What do you like most about Cloudflare Access?
The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good.
What is your experience regarding pricing and costs for Cloudflare Access?
The price of Cloudflare Access is the same as compared to Akamai, but I get better performance from Cloudflare. My co...
What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
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Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Cloudflare One and other solutions. Updated: June 2025.
858,469 professionals have used our research since 2012.