Morphisec vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

Morphisec and ThreatLocker are both solutions in the Endpoint Protection Platform (EPP) category. Morphisec is ranked #53, while ThreatLocker is ranked #6 with an average rating of 9.2. Morphisec holds a 0.6% mindshare in EPP, compared to ThreatLocker’s 1.1% mindshare. Additionally, 100% of Morphisec users are willing to recommend the solution, compared to 97% of ThreatLocker users who would recommend it.

Morphisec

Read 21 Morphisec reviews

2,216 Views
1,086 Comparison Views

100% willing to recommend

ThreatLocker Zero Trust End...

Read 40 ThreatLocker Zero Trust Endpoint Protection Platform reviews

3,305 Views
1,851 Comparison Views

97% willing to recommend

Morphisec

ThreatLocker Zero Trust End...

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Executive SummaryUpdated on Oct 5, 2025

Morphisec and ThreatLocker compete in the cybersecurity software category, both offering specialized features for endpoint protection. Morphisec seems to have the upper hand due to its seamless integration with Microsoft Defender and ease of use for non-IT specialists, providing significant peace of mind.

Features: Morphisec integrates with Microsoft Defender, providing comprehensive visibility into security events through a unified dashboard and employs a deterministic approach to prevent zero-day attacks without needing prior knowledge or signatures. It is lightweight and operates silently without hindering endpoint performance. ThreatLocker's platform focuses on whitelist-based protection, emphasizing application control, ring-fencing, and selective elevation to secure endpoints and ensure application compliance with cybersecurity guidelines. It offers excellent support resources to enhance the user experience and features a robust admin approval process for application access.

Room for Improvement: Morphisec could improve customer interaction and alert clarity, as some users find it challenging to understand the protection level. Its reporting capabilities and network discovery features could be expanded. ThreatLocker faces comments about its steep learning curve, with users desiring a more intuitive interface and additional training resources. Challenges with policy application bandwidth management and better integration with PSA systems are noted.

Ease of Deployment and Customer Service: Both Morphisec and ThreatLocker offer on-premises, cloud, and hybrid deployment options, ensuring flexibility. Morphisec is praised for its customer service, although time zone differences with Israeli-based teams can pose challenges. ThreatLocker is known for high-quality support with quick responses, though more advanced queries and policy setup complexities sometimes require improvement.

Pricing and ROI: Morphisec is competitively priced, offering savings compared to solutions like CrowdStrike, with a straightforward pricing model. ThreatLocker is perceived as reasonably priced, providing a comprehensive feature set with flexibility in pricing. Both platforms report positive ROI, mainly through reduced security incidents and less administrative workload, enabling teams to focus on strategic tasks.

To learn more, read our detailed Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform Report (Updated: December 2025).

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

December 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Morphisec

Ranking in Endpoint Protection Platform (EPP)

53rd

Ranking in Advanced Threat Protection (ATP)

33rd

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Vulnerability Management (55th), Endpoint Detection and Response (EDR) (61st), Cloud Workload Protection Platforms (CWPP) (34th), Threat Deception Platforms (18th)

ThreatLocker Zero Trust End...

Ranking in Endpoint Protection Platform (EPP)

6th

Ranking in Advanced Threat Protection (ATP)

7th

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Network Access Control (NAC) (5th), Application Control (1st), ZTNA (4th), Ransomware Protection (1st)

Mindshare comparison

As of January 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Morphisec is 0.6%, up from 0.4% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 1.1%, up from 0.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Endpoint Protection Platform (EPP) Market Share Distribution
Product	Market Share (%)
ThreatLocker Zero Trust Endpoint Protection Platform	1.1%
Morphisec	0.6%
Other	98.3%

Endpoint Protection Platform (EPP)

Featured Reviews

Rick Schibler

VP of Information Technology at Kentucky Trailer

Offers in-memory protection at a lower price than competitors

Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Read full review

Charles Loveland

Supervisor, Client Security at a consultancy with 11-50 employees

World-class support and highly effective for application control and elevation

Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have. Their idea portal, unlike so many other vendors we deal with, shows movement. At least four to eight features of ThreatLocker exist because I made a request in the last five years, and it became a feature of the actual product. When it comes to improvements, we moved the product as customers, and we got to move the product by making suggestions. They seem to be very reactive to it, so there is not a whole lot that they actively need to change right now. It is one of those situations where when we run into something that would be nice to have, it happens. They make it work.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"It provides full visibility into security events and from both solutions in one dashboard. I'm not a big security guy, if I have a threat that looks like there's a problem, I will ask Morphisec to dissect it for me, and tell me what might be happening. Because it tends to be all hash codes, so I can tell what's going on. They've been pretty good with that."

"All the alerts are on the dashboard, which is quite simple and useful for us. You can easily check all the alerts that are being blocked or allowed, or whatever the action is. You can easily see that and you can take the necessary actions. You can add a PowerShell extension or any activities for blocking at your network level or for endpoints."

"Morphisec provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. Defender and Morphisec are integrated. It's important because it lowers the total cost of maintenance on the engineer's time, more or less. So the administrative time is dramatically reduced in maintaining the product. This saves an engineer around four to five hours a week."

"Morphisec stops attacks without needing to know what type of threat it is, just that it is foreign. It is based on injections, so it would know when a software launches. If a software launches and something else also launches, then it would count that as anomalous and block it. Because the software looks at the code, and if it executes something else that is not related, then Morphisec would block it. That is how it works."

"Morphisec also provides full visibility into security events for Microsoft Defender and Morphisec in one dashboard... in the single pane of glass provided by Morphisec, it's all right there at your fingertips: easy to access and easy to understand. And if you choose to go down further to know everything from the process to the hash behind it, you can."

"Since using Morphisec we have seen a downturn in attacks because Morphisec protects us versus Defenders and whatnot that are signature-based. I know we have not had any issues with ransomware or other zero-day attacks that we've seen with machines that, all of a sudden, have become before we instituted the product. Now the machine had to be re-imaged and there was a loss of data because something was on the machine. You couldn't really determine what was on the machine because nothing was picking it up. The products we were using weren't picking it up."

"The biggest feature is that it hides everything from your operating system that's running in-memory from anything to try to run against it. That's the most unique thing that's on the market. There's nothing else out there that's quite like that. That's a big selling point and why we went with it. It does exactly what the design does. If you can't find it, you can't execute against it."

"Morphisec makes use of deterministic attack prevention that doesn’t require investigation of security alerts. It changes the memory locations of where certain applications run. If you think of Excel, opening a PDF, running an Excel macro, or opening a webpage and clicking on a link, all of those actions run in a certain area of memory. Morphisec changes the memory locations of where those run."

More Morphisec pros

"The Zero Trust factor is valuable because it blocks everything. That helps us to stay ahead of bad actors. We do not have to be in recovery mode."

"The control list is the best feature. For our company, it provides value to our customers since they can see we are improving our security."

"Feature-wise, the learning mode and the fact that it's blocking everything are the most valuable. I don't see why more companies don't use the type of product."

"ThreatLocker Protect has improved my organization greatly."

"Being able to protect and trust nothing by default, known as zero trust, is the most important feature to me."

"What sets ThreatLocker apart from competitors offering similar solutions is ringfencing. The ringfencing controls, along with the application elevation features, keep it out of the user's line of sight while still protecting them."

"Every single feature has been invaluable."

"We use it most heavily for elevation control, blocking and giving rights only to certain people or devices, and not allowing the rest to access the software. Elevation control has been second to none for me."

More ThreatLocker Zero Trust Endpoint Protection Platform pros

Cons

"We have discovered some bugs in the new releases that they've had to fix, so I would like to see more testing and QA on their side before they release."

"If anything, tech support might be their weakest link. The process of getting someone involved sometimes takes a little time. It seems to me that they should have all the data they need to let me know whether an alert is legitimate or not, but they tend to need a lot of information from me to get to the bottom of something. It usually takes a little longer than I would expect."

"We started in the Linux platform and we deployed to Linux. The licensing of that has been kind of confusing between Linux licensing and Windows licensing. The overall simplicity of licensing or offering an enterprise license to just cover everything and then we don't have to count needs improvement."

"The only area that really needs improvement is the reporting functionality. Gathering the detailed information that is in the system for an executive, or for me as a director, could be better. Some of the interface and reporting aspects are a little bit dated. They're working on it."

"It would be nice if they could integrate Morphisec with other traditional antivirus solutions beyond Microsoft Defender. That is probably my biggest gripe."

"From a company standpoint, a little more interaction with the customers throughout the year might be beneficial. I would like check-ins from the Morphisec account executives about any type of Morphisec news as well as a bit more interaction with customers throughout the year to know if anything new is coming out with Morphisec, e.g., what they are working on in regards to their development roadmap. We tend not to get that up until the time that we go for a yearly renewal. So, we end up talking to people from Morphisec once a year, but it is usually at renewal time."

"We sometimes have to depend on the support team to know what action we should take. If the solution for an alert can be built into the report that we are getting, it will save time, and the interaction with support would be less. At times, corrective action is required, but at times, we don't need to take any action. It would be good if we get to know in the report that a particular infection doesn't require any action. It will save us time and effort."

"I haven't been able to get the cloud deployment to work. When there's an update, I'm supposed to be able to roll it out for the cloud solution, but right now I'm continuing to use our SCCM solution to update it."

More Morphisec cons

"It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down."

"If you have a thousand computers with ThreatLocker agents on them, when you approve or create a new policy saying that Adobe Reader that matches this hashtag and meets certain criteria is allowed to be installed, it applies at the top level or the organization level. It applies to every computer in the company. When you make that new policy and push it out and it goes out and updates all of the clients. Unfortunately, at this time, it does not look like they stagger the push-out."

"Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have."

"ThreatLocker Allowlisting needs to improve its user interface and overall workflow."

"There could be options for handling a bulk amount of machines simultaneously."

"From my point of view, logging could be improved. Logging should be easier."

"If ThreatLocker can design or build something for mobile devices, that would be brilliant."

"Some reporting areas need improvement."

More ThreatLocker Zero Trust Endpoint Protection Platform cons

Pricing and Cost Advice

"Our licensing is tied into our contract. Because we have a long-term contract, our pricing is a little bit lower. It is per year, so we don't get charged per endpoint, but we do have a cap. Our cap is 80 endpoints. If we were to go over 80, when we renewed our contract, which is not until three years are over. Then, they would reevaluate, and say, "Well, you have more than 80 devices active right now. This is going to be the price change." They know that we are installing and replacing computers, so the numbers will be all over the place depending on whether you archive or don't archive, which is the reason why we just have to keep up on that stuff."

"It does not have multi-tenants. If South Africa wants to show only the machines that they have, they need their own cloud incidence. It is not possible to have that in a single cloud incidence with multiple tenants in it, instead you need to have multiple cloud incidences. Then, if you have that, it will be more expensive. However, they are going to change that, which is good."

"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."

"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."

"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."

"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."

"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."

"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."

More Morphisec pricing and cost advice

"The price of ThreatLocker Allowlisting is reasonable in the market, but it is not fantastic."

"Considering what this product does, ThreatLocker is very well-priced, if not too nicely priced for the customer."

"The pricing is fair and there is no hard sell."

"The pricing is reasonable and normal. I do not have any problems with the cost."

"Its price is fair. They have added some additional things to it beyond allowlisting. They are up-charging for them, but in terms of the value we get and the way it impacts us, we get a bang for our buck with ThreatLocker than a lot of our other security tools."

"I do not deal with pricing, but I assume it is cost-effective for us. We choose a solution based on functionality and affordability."

"ThreatLocker's pricing seems justifiable."

"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."

More ThreatLocker Zero Trust Endpoint Protection Platform pricing and cost advice

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Top Industries

By visitors reading reviews

Outsourcing Company

16%

Manufacturing Company

11%

Computer Software Company

Financial Services Firm

Computer Software Company

25%

Retailer

Manufacturing Company

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	5
Midsize Enterprise	8
Large Enterprise	8

By reviewers
Company Size	Count
Small Business	32
Midsize Enterprise	4
Large Enterprise	3

Questions from the Community

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What do you like most about ThreatLocker Allowlisting?

The interface is clean and well-organized, making it simple to navigate and find what we need.

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What is your experience regarding pricing and costs for ThreatLocker Allowlisting?

Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...

See all answers

What needs improvement with ThreatLocker Allowlisting?

Going with the theme of ThreatLocker Zero Trust Endpoint Protection Platform being a one-stop shop where they have just about everything, and they have a really good product stack as is. However, t...

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Comparisons

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Compared 18% of the time

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Compared 14% of the time

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Compared 11% of the time

SentinelOne Singularity Complete vs Morphisec

Compared 8% of the time

Hyver vs Morphisec

Compared 8% of the time

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CrowdStrike Falcon vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 10% of the time

Airlock Digital Application Control vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 8% of the time

Microsoft Defender for Endpoint vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 6% of the time

ManageEngine Application Control Plus vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 5% of the time

Ivanti Application Control vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 4% of the time

More ThreatLocker Zero Trust Endpoint Protection Platform Competitors

Product Reports

Buyer's Guide

Morphisec

December 2025

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Buyer's Guide

ThreatLocker Zero Trust Endpoint Protection Platform

December 2025

ThreatLocker Zero Trust Endpoint Protection Platform report

Download ThreatLocker Zero Trust Endpoint Protection Platform product report

Also Known As

Morphisec, Morphisec Moving Target Defense

Protect, Allowlisting, Network Control, Ringfencing

Overview

Morphisec integrates seamlessly with platforms like Microsoft Defender, offering signatureless protection against zero-day threats and ransomware. It enhances existing endpoint solutions with minimal maintenance through its set-and-forget deployment, providing heightened security and reduced false positives.

Morphisec strengthens defense strategies by merging memory morphing and signatureless protection to effectively block zero-day attacks and ransomware. It operates efficiently within existing infrastructure, reducing system impact and maintenance needs. Users find its full visibility dashboard invaluable. Despite its strengths, cloud deployment and reporting features can be improved. Stability, alerts, and integration with other systems pose challenges for users, impacting usability and support quality.

What are Morphisec's key features?

Seamless Integration: Works with Microsoft Defender for comprehensive dashboard visibility
Memory Morphing: Hides processes to reduce attack surfaces
Signatureless Protection: Prevents threats without impacting performance
Automatic Threat Blocking: Uses inbuilt intelligence to detect risks
Set-and-Forget Deployment: Simplifies management and reduces maintenance

What benefits should users consider in reviews?

Quick Deployment: Fast setup without disrupting operations
Enhanced Protection: Provides an additional defense layer against advanced threats
Cost-Effectiveness: Works with existing licenses, minimizing extra investments
Improved Compatibility: Integrates smoothly with current antivirus systems
Minimal System Impact: Operates efficiently without overloading resources

In security-focused industries, Morphisec is crucial for protecting workstations and servers against sophisticated attacks like ransomware. Its signatureless technology offers early threat detection, while compatibility with existing systems ensures seamless integration, providing advanced protection without additional licensing costs.

Morphisec

ThreatLocker Zero Trust Endpoint Protection Platform empowers organizations with application control, selective elevation, and ring-fencing to enhance security and prevent unauthorized access.

ThreatLocker provides comprehensive security management using application allowlisting to ensure only approved software operates across servers and workstations. The platform's centralized management simplifies security processes by consolidating multiple tools, and its robust capabilities align with zero-trust strategies by actively blocking unauthorized applications and ensuring compliance. Users note intuitive features such as mobile access, helpful training resources, and responsive support, which effectively reduce operational costs and help desk inquiries. The managed service providers prefer ThreatLocker to maintain network integrity by preventing malicious scripts and unauthorized access attempts. However, users identify room for growth in training and support flexibility, the interface, and certain technical challenges like network saturation from policy updates.

What are the most important features?

Application Control: Ensures only approved applications can be executed, minimizing security risks.
Selective Elevation: Provides granular control over application permissions without compromising security.
Ring-Fencing: Isolates applications to limit possible damage from compromised software.
Comprehensive Blocking: Blocks unauthorized applications, supporting zero-trust strategies.
Centralized Management: Offers a unified platform for managing security tools efficiently.

What benefits should users look for in reviews?

Intuitive Interface: Simplifies complex security processes, making them manageable for non-expert users.
Reduced Operational Costs: Minimizes resource expenditure through effective security management.
Enhanced Security: Provides robust protection against unauthorized access and malicious scripts.
Responsive Support: Offers quick and effective assistance to minimize downtime and issues.

Organizations utilize ThreatLocker for application allowlisting, ensuring only authorized software operates to prevent unauthorized access efficiently. Deployed across servers and workstations, its features support zero-trust principles and are favored by managed service providers for application management and network integrity.

ThreatLocker

Sample Customers

Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center

Information Not Available

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

December 2025

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