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Morphisec vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

Morphisec and ThreatLocker are both solutions in the Endpoint Protection Platform (EPP) category. Morphisec is ranked #53, while ThreatLocker is ranked #7 with an average rating of 9.2. Morphisec holds a 0.5% mindshare in EPP, compared to ThreatLocker’s 0.8% mindshare. Additionally, 100% of Morphisec users are willing to recommend the solution, compared to 97% of ThreatLocker users who would recommend it.

Morphisec

Read 21 Morphisec reviews

1,876 Views
1,069 Comparison Views

100% willing to recommend

ThreatLocker Zero Trust End...

Read 39 ThreatLocker Zero Trust Endpoint Protection Platform reviews

3,098 Views
2,045 Comparison Views

97% willing to recommend

Morphisec

ThreatLocker Zero Trust End...

Comparison Buyer's Guide

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Executive SummaryUpdated on Jun 29, 2025

Morphisec and ThreatLocker are both players in the endpoint protection category. Morphisec seems to have an edge in intuitive usability and seamless Microsoft Defender integration, whereas ThreatLocker excels with its comprehensive application control and zero trust approach.

Features: Morphisec provides visibility into security events alongside Microsoft Defender in a single dashboard, offers a signatureless and lightweight endpoint protection that doesn't affect performance, and employs deterministic attack prevention against zero-day and ransomware threats. ThreatLocker emphasizes application control and zero trust with allowlisting, ring-fencing, and elevation control, providing robust application management and enhanced visibility without requiring user intervention.

Room for Improvement: Morphisec could improve its reporting, dashboard functionality, and integration with other antivirus solutions to streamline operations. There are also challenges with false positives and update notifications. ThreatLocker has room to improve its UI and policy management, as well as its integration with PSA systems. The product has a steep learning curve and could benefit from enhanced training resources and an improved customer ticketing system for better responsiveness.

Ease of Deployment and Customer Service: Both Morphisec and ThreatLocker offer flexible deployment options, including on-premises, cloud, and hybrid environments. Morphisec's deployment is supported by strong technical assistance though it sometimes faces challenges with time zone differences. ThreatLocker benefits from effective support and proactive communication, though its learning curve and support during non-standard hours can be improved. Both companies are committed to customer service, with Morphisec having an effective follow-up system and ThreatLocker known for customer collaboration.

Pricing and ROI: Morphisec is competitively priced, offering a simple licensing model and significant ROI through reduced workloads and comprehensive threat coverage without additional costs. ThreatLocker is seen as reasonably priced with flexible pricing models that support business growth and are well-aligned with the perceived value, offering a strong cost-benefit ratio. Both solutions demonstrate compelling ROI through operational efficiency and robust threat prevention.

To learn more, read our detailed Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform Report (Updated: August 2025).

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

August 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Morphisec

Ranking in Endpoint Protection Platform (EPP)

53rd

Ranking in Advanced Threat Protection (ATP)

35th

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Vulnerability Management (64th), Endpoint Detection and Response (EDR) (60th), Cloud Workload Protection Platforms (CWPP) (33rd), Threat Deception Platforms (17th)

ThreatLocker Zero Trust End...

Ranking in Endpoint Protection Platform (EPP)

7th

Ranking in Advanced Threat Protection (ATP)

5th

Average Rating

9.2

Reviews Sentiment

7.5

Number of Reviews

Ranking in other categories

Network Access Control (NAC) (5th), Application Control (1st), ZTNA (3rd), Ransomware Protection (1st)

Mindshare comparison

As of August 2025, in the Endpoint Protection Platform (EPP) category, the mindshare of Morphisec is 0.5%, up from 0.3% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 0.8%, up from 0.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Endpoint Protection Platform (EPP)

Featured Reviews

Rick Schibler

VP of Information Technology at Kentucky Trailer

Offers in-memory protection at a lower price than competitors

Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Read full review

Johnathan Bodily

Technical Engineer at Cloud 1 Solutions

Ensures ransomware protection and reduces phishing chaos

The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The simplicity of the solution, how easy it is to deploy and how small it is when deployed as an agent on a device, is probably the biggest aspect, given what it can do."

"It provides full visibility into security events and from both solutions in one dashboard. I'm not a big security guy, if I have a threat that looks like there's a problem, I will ask Morphisec to dissect it for me, and tell me what might be happening. Because it tends to be all hash codes, so I can tell what's going on. They've been pretty good with that."

"Morphisec is a straightforward solution that is efficient and very stable."

"The biggest feature is that it hides everything from your operating system that's running in-memory from anything to try to run against it. That's the most unique thing that's on the market. There's nothing else out there that's quite like that. That's a big selling point and why we went with it. It does exactly what the design does. If you can't find it, you can't execute against it."

"Morphisec makes it very easy for IT teams of any size to prevent breaches of critical systems because of the design of their tool. When we evaluated Morphisec, the CIO and I sat and listened. What attracted us to them is the fact that it stops activity at the point of detection. That saves a lot of time because now we are not investigating and trying to trace down what to turn off. We have already prevented it, which makes it very much safer and more secure."

"The fact that Morphisec uses deterministic attack prevention that does not require human intervention has affected our security team's operations by making things much simpler. We don't have to really track down various alerts anymore, they've just stopped. At that point, we can go in and we can clean up whatever needs to be cleaned up. There are some things that Morphisec detects that we can't really remove, it's parts of Internet Explorer, but it's being blocked anyway. So we're happy with that."

"Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it."

"We don't have to do anything as a user or as an admin. It does everything by default with its coding and inbuilt AI-based intelligence. We don't have to instruct it about what to do. It automatically takes corrective actions and quarantines or deletes a virus, malware, etc. That is the best part that I like about it."

More Morphisec pros

"A few years back, we had an attack on one of our biggest clients."

"The sandbox functionality is fantastic."

"The great thing is that if you get a malicious email and you try to run something, ThreatLocker is not going to let it do anything. It is not going to let anything infect your network."

"The most valuable feature is its learning capability."

"The customer service is excellent, ten out of ten."

"ThreatLocker's most valuable feature is its scanning capability, which executes all types of executable files."

"The biggest one that we focus on is the application control with ringfencing. That combination is very beneficial."

"The application control is highly valued by me."

More ThreatLocker Zero Trust Endpoint Protection Platform pros

Cons

"If anything, tech support might be their weakest link. The process of getting someone involved sometimes takes a little time. It seems to me that they should have all the data they need to let me know whether an alert is legitimate or not, but they tend to need a lot of information from me to get to the bottom of something. It usually takes a little longer than I would expect."

"Right now, it's just their auto-update feature. I know they are currently working on that. When they release a new version of the threat prevention platform, I do have to update that, rolling out to every computer. They have said, "From version 5, you would be able to do an auto-update." While this is very minor, that is the only thing that I would say needs to be upgraded. It would just make life a lot easier for other IT teams. However, I have simplified the process, so all I need to do is just download one file."

"We sometimes have to depend on the support team to know what action we should take. If the solution for an alert can be built into the report that we are getting, it will save time, and the interaction with support would be less. At times, corrective action is required, but at times, we don't need to take any action. It would be good if we get to know in the report that a particular infection doesn't require any action. It will save us time and effort."

"Those are some of the features that I was looking for on my on-prem platform that they've already instituted in the cloud and that I'm sure will be instituting on their on-prem platform as well. Having to have an on-prem server required a lot of administration. Being able to push that to the cloud and have it managed up there for us is a real nice addition."

"The dashboard is the area that requires the most improvement. We have about, I would say 5,500 computers currently, and searching through all of those takes some time to filter. So as soon as you apply the filter, it takes a few seconds. It crunches, it thinks, and then it brings up the clients that match."

"It might be a bit much to ask, but we are now beginning to use Morphisec Scout, which provides vulnerability information. At this time, it's recognizing vulnerabilities and reporting them to us, but it's not necessarily resolving them. There's still a separate manual process to resolve those vulnerabilities, primarily through upgrades. We have to do that outside of Morphisec. If Morphisec could somehow have that capability built into it, that would be very effective."

"We have discovered some bugs in the new releases that they've had to fix, so I would like to see more testing and QA on their side before they release."

"The only area that really needs improvement is the reporting functionality. Gathering the detailed information that is in the system for an executive, or for me as a director, could be better. Some of the interface and reporting aspects are a little bit dated. They're working on it."

More Morphisec cons

"ThreatLocker Allowlisting needs to improve its user interface and overall workflow."

"It would be beneficial if it became more recognized in the EU to gain respect."

"I find that the learning mode is too accessible. Technicians sometimes default to it instead of manually building policy controls."

"It has not helped reduce our help desk tickets. We are still in learning mode, and after we are fully knowledgeable, we will be able to see some ticket reductions."

"The snapshots used in the ThreatLocker University portal are outdated snippets and have not been updated in conjunction with the portal itself."

"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."

"There could be options for handling a bulk amount of machines simultaneously."

"We also have customers who are frustrated because they cannot do what they used to do, which was run anything they wanted to."

More ThreatLocker Zero Trust Endpoint Protection Platform cons

Pricing and Cost Advice

"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."

"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."

"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."

"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."

"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."

"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."

"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."

"The pricing is definitely fair for what it does."

More Morphisec pricing and cost advice

"I do not deal with pricing, but I assume it is cost-effective for us. We choose a solution based on functionality and affordability."

"The price is very reasonable, and we have been able to integrate ThreatLocker with all of our clients."

"We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This was primarily a mistake on our part due to how we initially priced it to clients."

"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."

"Others say ThreatLocker is too expensive, and I tell them they're dreaming. It's well-priced for what it does."

"Its price is fair. They have added some additional things to it beyond allowlisting. They are up-charging for them, but in terms of the value we get and the way it impacts us, we get a bang for our buck with ThreatLocker than a lot of our other security tools."

"ThreatLocker's pricing seems justifiable."

"The pricing is fair and there is no hard sell."

More ThreatLocker Zero Trust Endpoint Protection Platform pricing and cost advice

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Top Industries

By visitors reading reviews

Outsourcing Company

15%

Manufacturing Company

11%

Computer Software Company

10%

Financial Services Firm

Computer Software Company

31%

Retailer

Manufacturing Company

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

Questions from the Community

Ask a question

Earn 20 points

What do you like most about ThreatLocker Allowlisting?

The interface is clean and well-organized, making it simple to navigate and find what we need.

See all answers

What is your experience regarding pricing and costs for ThreatLocker Allowlisting?

Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...

See all answers

What needs improvement with ThreatLocker Allowlisting?

For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...

See all answers

Comparisons

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Compared 24% of the time

Halcyon vs Morphisec

Compared 16% of the time

SentinelOne Singularity Complete vs Morphisec

Compared 11% of the time

Deep Instinct Prevention Platform vs Morphisec

Compared 10% of the time

Hyver vs Morphisec

Compared 9% of the time

More Morphisec Competitors

CrowdStrike Falcon vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 14% of the time

Microsoft Defender for Endpoint vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 11% of the time

SentinelOne Singularity Complete vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 11% of the time

Ivanti Application Control vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 5% of the time

ManageEngine Application Control Plus vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 5% of the time

More ThreatLocker Zero Trust Endpoint Protection Platform Competitors

Product Reports

Buyer's Guide

Morphisec

August 2025

Download Morphisec product report

Buyer's Guide

ThreatLocker Zero Trust Endpoint Protection Platform

July 2025

ThreatLocker Zero Trust Endpoint Protection Platform report

Download ThreatLocker Zero Trust Endpoint Protection Platform product report

Also Known As

Morphisec, Morphisec Moving Target Defense

Protect, Allowlisting, Network Control, Ringfencing

Overview

Morphisec integrates seamlessly with platforms like Microsoft Defender, offering signatureless protection against zero-day threats and ransomware. It enhances existing endpoint solutions with minimal maintenance through its set-and-forget deployment, providing heightened security and reduced false positives.

Morphisec strengthens defense strategies by merging memory morphing and signatureless protection to effectively block zero-day attacks and ransomware. It operates efficiently within existing infrastructure, reducing system impact and maintenance needs. Users find its full visibility dashboard invaluable. Despite its strengths, cloud deployment and reporting features can be improved. Stability, alerts, and integration with other systems pose challenges for users, impacting usability and support quality.

What are Morphisec's key features?

Seamless Integration: Works with Microsoft Defender for comprehensive dashboard visibility
Memory Morphing: Hides processes to reduce attack surfaces
Signatureless Protection: Prevents threats without impacting performance
Automatic Threat Blocking: Uses inbuilt intelligence to detect risks
Set-and-Forget Deployment: Simplifies management and reduces maintenance

What benefits should users consider in reviews?

Quick Deployment: Fast setup without disrupting operations
Enhanced Protection: Provides an additional defense layer against advanced threats
Cost-Effectiveness: Works with existing licenses, minimizing extra investments
Improved Compatibility: Integrates smoothly with current antivirus systems
Minimal System Impact: Operates efficiently without overloading resources

In security-focused industries, Morphisec is crucial for protecting workstations and servers against sophisticated attacks like ransomware. Its signatureless technology offers early threat detection, while compatibility with existing systems ensures seamless integration, providing advanced protection without additional licensing costs.

Morphisec

ThreatLocker Zero Trust Endpoint Protection Platform offers robust endpoint security through application control and allowlisting, safeguarding servers and workstations from unauthorized software execution.

ThreatLocker Zero Trust Endpoint Protection Platform provides extensive application control with features like ring-fencing and selective elevation, ensuring meticulous execution management. Offering learning mode and extensive support, it integrates threat detection and activity monitoring to enhance compliance, reduce costs, and bolster cybersecurity through alerts and approvals. Despite its strengths, there are areas for improvement in training flexibility, policy updates, and interface enhancements, along with challenges in handling non-digitally signed software. Deployed across environments, it works well with existing cybersecurity instruments for real-time threat prevention.

What are the top features of ThreatLocker?

Intuitive Interface: User-friendly design simplifies endpoint protection management.
Application Blocking: Prevents unauthorized applications from running.
Selective Elevation: Grants control over application permissions.
Ring-Fencing: Isolates applications to limit interactions.
Allowlisting: Ensures only trusted software can execute.
Learning Mode: Facilitates configuration by observing user behavior.
Real-Time Support: Access to assistance and training resources.

What benefits should reviewers seek?

Compliance: Meets regulatory standards.
Operational Cost Reduction: Consolidated alerts and approvals.
Enhanced Cybersecurity: Prevention of unauthorized applications.
Regulatory Alignment: Helps ensure adherence to legal requirements.

ThreatLocker Zero Trust Endpoint Protection Platform is widely implemented to safeguard IT infrastructures against unauthorized access and application use. In sectors where data security is paramount, this platform enables users to prevent unauthorized software installations and control device applications, ensuring real-time threat prevention and compliance with industry regulations.

ThreatLocker

Sample Customers

Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center

Information Not Available

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

August 2025

Free Report: Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

Find out what your peers are saying about Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: August 2025.

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