Morphisec vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

Morphisec and ThreatLocker are both solutions in the Endpoint Protection Platform (EPP) category. Morphisec is ranked #54, while ThreatLocker is ranked #7 with an average rating of 9.2. Morphisec holds a 0.5% mindshare in EPP, compared to ThreatLocker’s 0.9% mindshare. Additionally, 100% of Morphisec users are willing to recommend the solution, compared to 97% of ThreatLocker users who would recommend it.

Morphisec

Read 21 Morphisec reviews

1,975 Views
1,067 Comparison Views

100% willing to recommend

ThreatLocker Zero Trust End...

Read 40 ThreatLocker Zero Trust Endpoint Protection Platform reviews

3,141 Views
1,947 Comparison Views

97% willing to recommend

Morphisec

ThreatLocker Zero Trust End...

Comparison Buyer's Guide

Download the report

Executive SummaryUpdated on Oct 5, 2025

Morphisec and ThreatLocker compete in the cybersecurity software category, both offering specialized features for endpoint protection. Morphisec seems to have the upper hand due to its seamless integration with Microsoft Defender and ease of use for non-IT specialists, providing significant peace of mind.

Features: Morphisec integrates with Microsoft Defender, providing comprehensive visibility into security events through a unified dashboard and employs a deterministic approach to prevent zero-day attacks without needing prior knowledge or signatures. It is lightweight and operates silently without hindering endpoint performance. ThreatLocker's platform focuses on whitelist-based protection, emphasizing application control, ring-fencing, and selective elevation to secure endpoints and ensure application compliance with cybersecurity guidelines. It offers excellent support resources to enhance the user experience and features a robust admin approval process for application access.

Room for Improvement: Morphisec could improve customer interaction and alert clarity, as some users find it challenging to understand the protection level. Its reporting capabilities and network discovery features could be expanded. ThreatLocker faces comments about its steep learning curve, with users desiring a more intuitive interface and additional training resources. Challenges with policy application bandwidth management and better integration with PSA systems are noted.

Ease of Deployment and Customer Service: Both Morphisec and ThreatLocker offer on-premises, cloud, and hybrid deployment options, ensuring flexibility. Morphisec is praised for its customer service, although time zone differences with Israeli-based teams can pose challenges. ThreatLocker is known for high-quality support with quick responses, though more advanced queries and policy setup complexities sometimes require improvement.

Pricing and ROI: Morphisec is competitively priced, offering savings compared to solutions like CrowdStrike, with a straightforward pricing model. ThreatLocker is perceived as reasonably priced, providing a comprehensive feature set with flexibility in pricing. Both platforms report positive ROI, mainly through reduced security incidents and less administrative workload, enabling teams to focus on strategic tasks.

To learn more, read our detailed Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform Report (Updated: September 2025).

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

September 2025

Download the complete report

Helped 869,566 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Morphisec

Ranking in Endpoint Protection Platform (EPP)

54th

Ranking in Advanced Threat Protection (ATP)

34th

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Vulnerability Management (64th), Endpoint Detection and Response (EDR) (61st), Cloud Workload Protection Platforms (CWPP) (31st), Threat Deception Platforms (15th)

ThreatLocker Zero Trust End...

Ranking in Endpoint Protection Platform (EPP)

7th

Ranking in Advanced Threat Protection (ATP)

6th

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Network Access Control (NAC) (5th), Application Control (1st), ZTNA (4th), Ransomware Protection (1st)

Mindshare comparison

As of October 2025, in the Endpoint Protection Platform (EPP) category, the mindshare of Morphisec is 0.5%, up from 0.4% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 0.9%, up from 0.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Endpoint Protection Platform (EPP) Market Share Distribution
Product	Market Share (%)
ThreatLocker Zero Trust Endpoint Protection Platform	0.9%
Morphisec	0.5%
Other	98.6%

Endpoint Protection Platform (EPP)

Featured Reviews

Rick Schibler

VP of Information Technology at Kentucky Trailer

Offers in-memory protection at a lower price than competitors

Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Read full review

Johnathan Bodily

Technical Engineer at Cloud 1 Solutions

Ensures ransomware protection and reduces phishing chaos

The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"Morphisec makes it very easy for IT teams of any size to prevent breaches of critical systems because of the design of their tool. When we evaluated Morphisec, the CIO and I sat and listened. What attracted us to them is the fact that it stops activity at the point of detection. That saves a lot of time because now we are not investigating and trying to trace down what to turn off. We have already prevented it, which makes it very much safer and more secure."

"I really like the integration with Microsoft Defender. In addition to having third-party endpoint protection, we're also enabling Defender... I like the reporting that we get from Defender, when it comes in. I like that it's one console showing both Morphisec and Defender where it provides me with full visibility into security events from Defender and Morphisec."

"Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it."

"Morphisec has absolutely helped save money on our security stack. The ransomware at the end of the day can cost organizations millions upon millions of dollars. Investing in tools like Morphisec is a great reduction in that cost. If I can spend $10,000 in a year to protect assets that could be ransomed for $20,000,000, that's definitely a bet that one should pursue. Morphisec absolutely it's worth the investment."

"The fact that Morphisec uses deterministic attack prevention that does not require human intervention has affected our security team's operations by making things much simpler. We don't have to really track down various alerts anymore, they've just stopped. At that point, we can go in and we can clean up whatever needs to be cleaned up. There are some things that Morphisec detects that we can't really remove, it's parts of Internet Explorer, but it's being blocked anyway. So we're happy with that."

"Morphisec also provides full visibility into security events for Microsoft Defender and Morphisec in one dashboard... in the single pane of glass provided by Morphisec, it's all right there at your fingertips: easy to access and easy to understand. And if you choose to go down further to know everything from the process to the hash behind it, you can."

"What's valuable is really the whole kit and caboodle of the Morphisec agent. What it does is genius, in a way, until the bad guys get wise to it. You set it up and then you watch the dashboard. There isn't really much tinkering."

"Morphisec makes use of deterministic attack prevention that doesn’t require investigation of security alerts. It changes the memory locations of where certain applications run. If you think of Excel, opening a PDF, running an Excel macro, or opening a webpage and clicking on a link, all of those actions run in a certain area of memory. Morphisec changes the memory locations of where those run."

More Morphisec pros

"We use ThreatLocker's Allowlisting to whitelist specific applications and prevent unauthorized software from running."

"The great thing is that if you get a malicious email and you try to run something, ThreatLocker is not going to let it do anything. It is not going to let anything infect your network."

"ThreatLocker Protect has improved my organization greatly."

"A few years back, we had an attack on one of our biggest clients."

"It's easy to use in regards to reducing attack surfaces."

"ThreatLocker’s support has been second to none."

"We use it most heavily for elevation control, blocking and giving rights only to certain people or devices, and not allowing the rest to access the software. Elevation control has been second to none for me."

"The unified alerts are useful."

More ThreatLocker Zero Trust Endpoint Protection Platform pros

Cons

"Automating reports needs improvement. I would like to have better reporting capabilities within it or automated reporting to be a little bit more dynamic. That's something I know they're working on. We literally are in the process. We started the process a week and a half ago of going to their latest version, so I've not seen their latest one up and running yet."

"It would be useful for them if they had some kind of network discovery. That kind of functionality I think would give IT administrators a little bit more confidence that they have 100 percent coverage, and it gives them something to audit against. Network discovery would be one area I would definitely suggest that they put some effort into."

"It might be a bit much to ask, but we are now beginning to use Morphisec Scout, which provides vulnerability information. At this time, it's recognizing vulnerabilities and reporting them to us, but it's not necessarily resolving them. There's still a separate manual process to resolve those vulnerabilities, primarily through upgrades. We have to do that outside of Morphisec. If Morphisec could somehow have that capability built into it, that would be very effective."

"In the Windows Defender integration, they have put in a report of computers that need Windows Defender updates. If those updates could be kicked off directly from the dashboard, instead of having to go to another system entirely, that would be good."

"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."

"We have only had four attacks in the last year, "attacks" being some benign PDF from a vendor that, for some reason, were triggered. There were no actual attacks. They were just four false positives, or something lowly like adware. There have been false positives with both the on-premises solution and the cloud solution."

"Right now, it's just their auto-update feature. I know they are currently working on that. When they release a new version of the threat prevention platform, I do have to update that, rolling out to every computer. They have said, "From version 5, you would be able to do an auto-update." While this is very minor, that is the only thing that I would say needs to be upgraded. It would just make life a lot easier for other IT teams. However, I have simplified the process, so all I need to do is just download one file."

"It would be nice if they could integrate Morphisec with other traditional antivirus solutions beyond Microsoft Defender. That is probably my biggest gripe."

More Morphisec cons

"I was discussing with someone the other day, and it seems there is currently no solution for mobile users."

"The company should strive to stay ahead of all the developments happening externally. If their progress accelerates more rapidly than the ongoing changes outside, it would prove advantageous."

"More visibility in the built-ins would be nice."

"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."

"We identified several areas that we would like to see improved."

"Adding applications to the allowlist can sometimes feel overwhelming."

"The support could be quicker."

"The reporting could be improved."

More ThreatLocker Zero Trust Endpoint Protection Platform cons

Pricing and Cost Advice

"The pricing is definitely fair for what it does."

"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."

"Our licensing is tied into our contract. Because we have a long-term contract, our pricing is a little bit lower. It is per year, so we don't get charged per endpoint, but we do have a cap. Our cap is 80 endpoints. If we were to go over 80, when we renewed our contract, which is not until three years are over. Then, they would reevaluate, and say, "Well, you have more than 80 devices active right now. This is going to be the price change." They know that we are installing and replacing computers, so the numbers will be all over the place depending on whether you archive or don't archive, which is the reason why we just have to keep up on that stuff."

"It does not have multi-tenants. If South Africa wants to show only the machines that they have, they need their own cloud incidence. It is not possible to have that in a single cloud incidence with multiple tenants in it, instead you need to have multiple cloud incidences. Then, if you have that, it will be more expensive. However, they are going to change that, which is good."

"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."

"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."

"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."

"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."

More Morphisec pricing and cost advice

"The pricing is fair and there is no hard sell."

"The pricing works fine for me. It's very reasonably priced."

"I do not deal with pricing, but I assume it is cost-effective for us. We choose a solution based on functionality and affordability."

"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."

"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."

"Its price is fair. They have added some additional things to it beyond allowlisting. They are up-charging for them, but in terms of the value we get and the way it impacts us, we get a bang for our buck with ThreatLocker than a lot of our other security tools."

"The pricing is pretty fair, considering other solutions. Licensing-wise, it did not take long."

"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."

More ThreatLocker Zero Trust Endpoint Protection Platform pricing and cost advice

See which vendors are best for you

Use our free recommendation engine to learn which Endpoint Protection Platform (EPP) solutions are best for your needs.

See recommendations

869,566 professionals have used our research since 2012.

Top Industries

By visitors reading reviews

Outsourcing Company

16%

Manufacturing Company

12%

Computer Software Company

Financial Services Firm

Computer Software Company

28%

Retailer

Manufacturing Company

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	5
Midsize Enterprise	8
Large Enterprise	8

By reviewers
Company Size	Count
Small Business	32
Midsize Enterprise	4
Large Enterprise	3

Questions from the Community

Ask a question

Earn 20 points

What do you like most about ThreatLocker Allowlisting?

The interface is clean and well-organized, making it simple to navigate and find what we need.

See all answers

What is your experience regarding pricing and costs for ThreatLocker Allowlisting?

Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...

See all answers

What needs improvement with ThreatLocker Allowlisting?

For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...

See all answers

Comparisons

CrowdStrike Falcon vs Morphisec

Compared 22% of the time

Halcyon vs Morphisec

Compared 19% of the time

SentinelOne Singularity Complete vs Morphisec

Compared 11% of the time

Hyver vs Morphisec

Compared 11% of the time

Deep Instinct Prevention Platform vs Morphisec

Compared 11% of the time

More Morphisec Competitors

CrowdStrike Falcon vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 14% of the time

Microsoft Defender for Endpoint vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 10% of the time

SentinelOne Singularity Complete vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 7% of the time

ManageEngine Application Control Plus vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 6% of the time

Airlock Digital Application Control vs ThreatLocker Zero Trust Endpoint Protection Platform

Compared 6% of the time

More ThreatLocker Zero Trust Endpoint Protection Platform Competitors

Product Reports

Buyer's Guide

Morphisec

September 2025

Download Morphisec product report

Buyer's Guide

ThreatLocker Zero Trust Endpoint Protection Platform

September 2025

ThreatLocker Zero Trust Endpoint Protection Platform report

Download ThreatLocker Zero Trust Endpoint Protection Platform product report

Also Known As

Morphisec, Morphisec Moving Target Defense

Protect, Allowlisting, Network Control, Ringfencing

Overview

Morphisec integrates seamlessly with platforms like Microsoft Defender, offering signatureless protection against zero-day threats and ransomware. It enhances existing endpoint solutions with minimal maintenance through its set-and-forget deployment, providing heightened security and reduced false positives.

Morphisec strengthens defense strategies by merging memory morphing and signatureless protection to effectively block zero-day attacks and ransomware. It operates efficiently within existing infrastructure, reducing system impact and maintenance needs. Users find its full visibility dashboard invaluable. Despite its strengths, cloud deployment and reporting features can be improved. Stability, alerts, and integration with other systems pose challenges for users, impacting usability and support quality.

What are Morphisec's key features?

Seamless Integration: Works with Microsoft Defender for comprehensive dashboard visibility
Memory Morphing: Hides processes to reduce attack surfaces
Signatureless Protection: Prevents threats without impacting performance
Automatic Threat Blocking: Uses inbuilt intelligence to detect risks
Set-and-Forget Deployment: Simplifies management and reduces maintenance

What benefits should users consider in reviews?

Quick Deployment: Fast setup without disrupting operations
Enhanced Protection: Provides an additional defense layer against advanced threats
Cost-Effectiveness: Works with existing licenses, minimizing extra investments
Improved Compatibility: Integrates smoothly with current antivirus systems
Minimal System Impact: Operates efficiently without overloading resources

In security-focused industries, Morphisec is crucial for protecting workstations and servers against sophisticated attacks like ransomware. Its signatureless technology offers early threat detection, while compatibility with existing systems ensures seamless integration, providing advanced protection without additional licensing costs.

Morphisec

ThreatLocker Zero Trust Endpoint Protection Platform offers robust endpoint security through application control and allowlisting, safeguarding servers and workstations from unauthorized software execution.

ThreatLocker Zero Trust Endpoint Protection Platform provides extensive application control with features like ring-fencing and selective elevation, ensuring meticulous execution management. Offering learning mode and extensive support, it integrates threat detection and activity monitoring to enhance compliance, reduce costs, and bolster cybersecurity through alerts and approvals. Despite its strengths, there are areas for improvement in training flexibility, policy updates, and interface enhancements, along with challenges in handling non-digitally signed software. Deployed across environments, it works well with existing cybersecurity instruments for real-time threat prevention.

What are the top features of ThreatLocker?

Intuitive Interface: User-friendly design simplifies endpoint protection management.
Application Blocking: Prevents unauthorized applications from running.
Selective Elevation: Grants control over application permissions.
Ring-Fencing: Isolates applications to limit interactions.
Allowlisting: Ensures only trusted software can execute.
Learning Mode: Facilitates configuration by observing user behavior.
Real-Time Support: Access to assistance and training resources.

What benefits should reviewers seek?

Compliance: Meets regulatory standards.
Operational Cost Reduction: Consolidated alerts and approvals.
Enhanced Cybersecurity: Prevention of unauthorized applications.
Regulatory Alignment: Helps ensure adherence to legal requirements.

ThreatLocker Zero Trust Endpoint Protection Platform is widely implemented to safeguard IT infrastructures against unauthorized access and application use. In sectors where data security is paramount, this platform enables users to prevent unauthorized software installations and control device applications, ensuring real-time threat prevention and compliance with industry regulations.

ThreatLocker

Sample Customers

Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center

Information Not Available

Buyer's Guide

Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

September 2025

Free Report: Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform

Find out what your peers are saying about Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: September 2025.

DOWNLOAD NOW

869,566 professionals have used our research since 2012.

See our Morphisec vs. ThreatLocker Zero Trust Endpoint Protection Platform report.

See our list of best Endpoint Protection Platform (EPP) vendors and best Advanced Threat Protection (ATP) vendors.

We monitor all Endpoint Protection Platform (EPP) reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.