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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
4th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
214
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
23rd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of May 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.7%, down from 7.7% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.7%
Trellix Advanced Threat Defense2.1%
Other92.2%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable feature of Microsoft Defender for Endpoint is that it is embedded into the Windows system, and the performance is good and simple to maintain."
"The main benefits are compliance and protection from threats, helping us avoid disruption in the business and maintain uptime while prioritizing threats across our enterprise, which is very important for us."
"We have very good visibility on our endpoints. The level of information it throws back is helpful."
"Microsoft Defender for Endpoint has significantly impacted our security posture."
"It is very stable, highly recommended, free with the purchase of Windows Server, and it is doing its job for Microsoft Windows Server as a good product."
"There is no licensing fee, as Microsoft Defender for Endpoint comes included with the Windows license."
"I find the vulnerability management section of Microsoft Defender for Endpoint to be very useful for organizations."
"In Windows 11, Defender is very, very strong."
"The product is expensive, but it is better than the rest of them in the industry."
"I recommend this solution because of its ease of use."
"It is very scalable."
"The most valuable features are the administration console and its detection and response module."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is stable and reliable."
"Provides good exfiltration, and is an all-in-one product."
 

Cons

"The initial support process can be lacking as first-line support is sometimes not well-versed technically, resulting in repeated exchanges to finally engage a knowledgeable support person."
"Microsoft has some creative accounting when they promise an SLA of 99.99%. But it is generally good."
"I think the console can be better. The end-user also cannot do some advanced actions on it."
"The GUI is very complex and could be more user friendly."
"The solution can be more user-friendly."
"There could be an increase in security for the solution."
"Windows Defender, which is just a free version, is not as effective. It doesn't have deep support or deep protection."
"The user interface could use some improvement."
"We'd like them to be better at dealing with script threats."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"This product does the job, but it is not flexible enough to do new environments yet."
"Lacks remote capabilities not dependent on the internet."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"The support on their side is not readily available. It takes a while."
"This solution needs to be made "cloud ready"."
 

Pricing and Cost Advice

"The base price for an E5 license, which includes Enterprise Mobility + Security E5, is $57 per user per month."
"Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"The license for Microsoft Windows covers Microsoft Defender for Endpoint."
"Licensing fees are paid annually through a partner."
"The solutions price could be cheaper."
"The solution comes as part of Microsoft Windows."
"Most people don't realize M365/E5 licenses are an amazing deal. They think "Oh, it's expensive," and I'll ask, "Compared to what?" If you don't have it you will have to buy licenses for multiple products to fill the same security space that you would have gotten with the Microsoft product. Go figure out how much it costs you per product, per user, and then come back and tell me how things add up financially."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Computer Software Company
9%
Financial Services Firm
9%
Manufacturing Company
9%
Government
8%
Construction Company
16%
Comms Service Provider
12%
Outsourcing Company
11%
Financial Services Firm
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise95
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: April 2026.
893,311 professionals have used our research since 2012.