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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of August 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.8%, down from 7.7% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.8%
Trellix Advanced Threat Defense1.9%
Other92.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I am using it for very simple purposes. It is perfect and quite effective. I have been using it for a while, and I have never had any virus infection, data leak, or other security breaches. It works fine for standalone purposes. If you log on to OneDrive, it has ransomware protection."
"We had Norton Antivirus before, and with Norton, we didn't have a way to centrally manage a lot of features. Defender allowed us to deploy it from our Office 365 admin console. That is probably the biggest thing that made us go with Defender."
"I've started to test it from the security point of view. There are plenty of features that are interesting, but at this time, the XDR functionality is most valuable. It is endpoint security on steroids."
"The folders and files protection are its most valuable features. These have been valuable because of the increase in ransomware attacks. With these two features, I can ensure that no changes have been made to our system or endpoint folders and files without the user being aware."
"The performance of Microsoft Defender for Endpoint has been a valuable feature."
"This is the best feature of having OneDrive backup on the fly and recovery on the fly."
"It's free. There is no additional cost. It's part of Windows."
"Microsoft Defender for Endpoint has changed significantly for the better."
"It was easy to set up initially."
"The product is expensive, but it is better than the rest of them in the industry."
"It is very scalable."
"The most valuable features are the administration console and its detection and response module."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is stable and reliable."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
 

Cons

"It has not yet saved any time. It has only consumed my time for now because I need to learn and do the training and PoCs, but it is an investment for the future."
"There is some functionality that is not quite there yet."
"A single dashboard would be a significant improvement."
"Lowering the price would be an improvement."
"The UI for Microsoft Defender for Endpoint needs to be better."
"There's scanning going on that occasionally topples the memory, causing everything to freeze. This should be fixed."
"The system can always be simplified and have a better integration check."
"It is inexpensive but could be cheaper like anything else."
"The support on their side is not readily available. It takes a while."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"Make the ATD appliance a part of the whole product offering and take the whole thing onto the cloud."
"Lacks remote capabilities not dependent on the internet."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"This solution needs to be made "cloud ready"."
"This product does the job, but it is not flexible enough to do new environments yet."
 

Pricing and Cost Advice

"The price is fair for the features Microsoft delivers. If you want tailor-made features, you have to mix different licenses. It isn't straightforward."
"You do not need to pay any additional costs for antivirus and anti-malware solutions for endpoint protection."
"Licensing options vary. Some customers buy it as an enterprise agreement and pay yearly. Others buy it as a CSP, so they pay per month. It completely depends on the customer's needs."
"The subscription is part of Windows, so we don't have to pay anything extra for this product."
"It is an expensive solution. It would be nice if it could be included with the Microsoft Office package."
"There is no license needed, the solution comes with Microsoft Windows."
"Microsoft Defender for Endpoint can be costly as a standalone solution."
"Even if you are not registered as a not-for-profit, the offering that they have is definitely worth consideration. This is in the sense that the E5 stack just gives you so many benefits. You get your entire productivity suite through Microsoft 365 apps. You get all your security and identity protection. You get the Defender for Endpoint and Defender for Identity. You get the cloud access security broker as well. You get Azure Active Directory Premium P2, which gives you so many good things that you can configure and deploy. You don't have to configure them on day one, but you have access to so many different tools that will protect your data, security, endpoints, and identities that you could build out a security strategy 18 months long, and slowly work your way through it, based on what you have available to you through your license."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
report
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908,858 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
9%
Computer Software Company
8%
Comms Service Provider
8%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: August 2026.
908,858 professionals have used our research since 2012.