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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
23rd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.8%, down from 7.5% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.0%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.8%
Trellix Advanced Threat Defense2.0%
Other92.2%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The features of Microsoft Defender for Endpoint that I like the most are that it is not a very intrusive product, so it is not using up a lot of compute."
"This is a really good product, it's user-friendly and offers us safety and security."
"The most valuable feature is its ability to effectively detect threats. It has the EDR feature, endpoint detection and response, and that is very good."
"It is easy to use because it is already pre-installed in Windows 10."
"The features I have found most valuable are the ransomware and malware protection. The solution detects malware live and whenever it detects suspicious activity, it quarantines it."
"It comes included with the Windows license."
"What I like best is that it is part of the operating system, as opposed to a third-party application."
"Overall, our security posture looks much better and our attack surfaces are limited."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The product is expensive, but it is better than the rest of them in the industry."
"Provides good exfiltration, and is an all-in-one product."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"The most valuable features are the administration console and its detection and response module."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
"It was easy to set up initially."
 

Cons

"We would like more customization, actually."
"The central console needs improvement. Both McAfee and Symantec antivirus have dashboards. These integrate with a server and work on my antivirus or some other product. However, with Microsoft Defender, you use Microsoft Group Policy Object. Defender does not provide a central console. Therefore, if you implement Defender, then maybe use another tool for the central view."
"The product development team makes frequent changes that affect the stability of the solution."
"The price, in general, could always be a little bit cheaper."
"They should come up with pre-built inner workflows."
"I would like to have additional features such as DNS lookup, which would help for detecting malicious sites."
"Their support is okay. We get support through Insight, which is also our CSP."
"In India at least, it seems to be a bit more expensive than other options."
"The support on their side is not readily available. It takes a while."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"We'd like them to be better at dealing with script threats."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"Lacks remote capabilities not dependent on the internet."
 

Pricing and Cost Advice

"The price was a problem for me three years ago, but they improved their E3, E5, and a la carte licensing. In other words, you have to get all of E5. That used to be a problem because you had E3, Defender, and guardrails, but you needed an E5 license to get the management suite and the analytics. It's more flexible now. You can switch from a la carte to the entire suite when it starts to make sense. It's becoming more economically competitive to go that route."
"The price is higher than others because it is doing more than what the others are doing."
"The solution comes as a part of Windows 10 and it is covered under its license."
"It is free. It is included in Windows 10."
"We are required to pay for the data we ingest, and increasing the data amount incurs additional expenses."
"Microsoft Defender ATP is expensive."
"The cost is high for E5 licenses, but if we go with the E3 license, most of the features are not covered."
"It is built into Windows 10. If our clients are using Microsoft Defender, the cost goes away for them."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
10%
Computer Software Company
9%
Comms Service Provider
8%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: June 2026.
900,838 professionals have used our research since 2012.