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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (2nd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
21st
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of December 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 7.5%, down from 9.2% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.2%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Endpoint7.5%
Trellix Advanced Threat Defense2.2%
Other90.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Overall, I recommend Microsoft Defender for Endpoint due to its features and capabilities, which cover more loopholes than other EDR solutions."
"Microsoft Defender for Endpoint is extremely stable."
"The most valuable feature is its ability to effectively detect threats. It has the EDR feature, endpoint detection and response, and that is very good."
"The most valuable feature of Microsoft Defender for Endpoint is that it is embedded into the Windows system. Additionally, the performance is good and simple to maintain."
"It is quite stable. We have not had any cases, i.e., viruses, that would require a reboot, etc. We have never had a situation where we needed to reinstall the tools as a result of the Defender application or a feature being corrupt."
"Real-time detection and cloud-based delivery of detections are highly efficient."
"I like the process visibility. This ability to visualize how something was executed is valuable, and the fact that Defender ATP is also linked to the threat intelligence that they have is also valuable. So, even if you have something that doesn't have a conventional signature, the fact that you get this strange execution means that you can detect things that are normally not visible."
"Microsoft Defender for Endpoint has helped free up my SOC team to work on other projects and tasks, and the automated reporting and dashboarding has saved them a lot of time, amounting to several man-hours."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"I recommend this solution because of its ease of use."
"It is stable and reliable."
"Provides good exfiltration, and is an all-in-one product."
"The most valuable features are the administration console and its detection and response module."
"It is very scalable."
 

Cons

"I would appreciate agentic protection as an additional feature in the next release to protect the agents that the business creates."
"Other vendors provide a lot of customization when it comes to integration, which every big organization requires. No big organization depends on one particular tool. Defender lacks that at this point."
"One thing that was lacking in Defender was web filtering. Its web filtering wasn't as comprehensive. Sophos was a little bit better than Defender for blocking URLs or installing programs."
"It can get a bit laggy sometimes. Other than that, we don't have any issues. They constantly tweak it and fix it up based on users' feedback. It has improved a lot over the past four years. Defender for Endpoint never really used to be a good endpoint security solution, but over the past couple of years, Microsoft has invested heavily in it. So, it has come a long way in all aspects of endpoint security. If they want to make it better, they should just continue investing in the current path of what they've been doing over the past couple of years."
"I would like to have additional features such as DNS lookup, which would help for detecting malicious sites."
"I am not sure if I will be using this product in the future because of the price."
"The solution could always be more secure."
"Monitoring can always be better, onboarding can be a little bit faster, log collection could be easier, they could streamline the dashboard. They could maybe split it up into different workspaces and have the ability to segment groups a little bit more."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"This solution needs to be made "cloud ready"."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"We'd like them to be better at dealing with script threats."
"Lacks remote capabilities not dependent on the internet."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
 

Pricing and Cost Advice

"Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs."
"The price is fair for the features Microsoft delivers. If you want tailor-made features, you have to mix different licenses. It isn't straightforward."
"We mostly use Microsoft products. We use Office 365, and we use Azure. We're also a Microsoft partner. So, the licensing was much cheaper for us, and at the same time, a lot of the features that we were looking for were included in Defender."
"We are using the free version."
"It's all pretty easy. For some clients, it's an easier sell because it's just an add-on to their existing Microsoft licensing and Office 365 licensing."
"Defender doesn't cost that much. When you use Microsoft technology, you can start with the free version and see how much the technology helps your organization solve security problems before you use the subscription. They also do this pay-as-you-go model, so you only pay when you use it."
"The licensing fee is a function of your Office 365 license. The feature set you get is a function of the license as well. There is probably an E2 version, an E3 version, and an E5 version. There are several versions, and not all features are the same. So, you might want to check what features you're expecting because you might get shocked. If you only have an E3 license, the capability isn't the same."
"There are different licenses, such as E3 and E5."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
8%
Government
8%
Government
14%
Comms Service Provider
13%
Performing Arts
11%
University
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: December 2025.
879,310 professionals have used our research since 2012.