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Cortex XDR by Palo Alto Networks vs Microsoft Defender XDR comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jul 27, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.7
Cortex XDR enhances threat prevention, compliance, and cost efficiency, providing rapid ROI and improved security and user satisfaction.
Sentiment score
6.7
Microsoft Defender XDR provides high ROI by consolidating security tools, streamlining operations, and enhancing security, despite licensing costs.
They appreciate the rich telemetry data from the solution, as it provides in-depth threat identification.
I have seen a return on investment with Cortex XDR by Palo Alto Networks, as this product is offered at a minimal cost, and we can find a good ROI from it.
We can quarantine and isolate a device within minutes.
Microsoft Defender XDR has saved me at least 50% of my time.
Ever since we turned on the M5 feature set back in June, we have seen a reduced number of potentially malicious clicks and faster alerting when incidents occur.
 

Customer Service

Sentiment score
6.6
Palo Alto Networks' customer service receives mixed reviews due to language barriers, response times, and inconsistent technical support quality.
Sentiment score
6.2
Microsoft Defender XDR's support is timely and responsive, yet smaller organizations experience slower, less effective assistance than larger ones.
Every vendor has similar support; it depends on how the case is handled and raised.
Their support is efficient and responsive whenever I raise a ticket through my portal.
I would rate technical support from Palo Alto on a scale from one to ten as an eight, as I find it good.
You get stuck in low-level support for way longer than you should, instead of them escalating the issue up the chain.
It's critical to escalate SEV B issues immediately to a domestic engineer.
Once issues are escalated to the second or third layer, the support is much better.
 

Scalability Issues

Sentiment score
7.6
Cortex XDR excels in scalability and adaptability across environments, supporting diverse systems with seamless deployment and reliable expansion.
Sentiment score
7.6
Microsoft Defender XDR scales well for various organizations, efficiently supporting growth and flexibility despite some network deployment challenges.
Microsoft Defender XDR shows tremendous scalability, much more so than on-premises solutions.
Microsoft Defender XDR scales pretty well.
It is suitable for enterprise-level deployment but has room for improvement.
 

Stability Issues

Sentiment score
8.0
Cortex XDR by Palo Alto Networks is stable and reliable, with quick bug fixes and consistent performance across platforms.
Sentiment score
8.0
Microsoft Defender XDR is praised for high stability, reliable performance, minimal issues, frequent updates, and prompt issue resolution.
Cortex XDR is stable, offering high quality and reliable performance.
For the last 11 months, we haven't faced any outage issues, so it is a stable product.
The service has remained consistently online, with any issues isolated to specific components, suggesting a well-designed and modular architecture.
The services within our ecosystem have been reliable, meeting their SLAs.
It provides high-fidelity signals.
 

Room For Improvement

Users find Cortex XDR challenging due to integration issues, high memory usage, limited features, and a need for improvements.
Microsoft Defender XDR requires enhancements in speed, integration, automation, AI, ease-of-use, and industry-specific threat intelligence.
The inclusion of this feature would allow the application of DLP policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products.
If the per GB data could be provided at a certain level free of cost or at the same cost which the customer is taking for the entire bundle, that would be better.
Cortex XDR could improve its sales support team, including better commission structures and referral programs.
The licensing process needs improvement and clarification.
Improvements are needed in automated response capabilities.
Some inconsistencies exist between blades, which could be improved for a more seamless user and UI experience.
 

Setup Cost

Cortex XDR offers flexible licensing, valued for complex security needs, but perceived as costly and variable in international markets.
Microsoft Defender XDR pricing is seen as complex but fair, with high costs alleviated in bundled Microsoft 365 packages.
Cortex XDR is perceived as expensive by some customers, yet offers dynamic pricing.
Compared to competitors such as CrowdStrike and Sophos, the pricing of Cortex XDR by Palo Alto Networks is similar to CrowdStrike but more expensive than Sophos.
There are certainly savings when using Microsoft Defender XDR, which can range from 30%, 40%, and even up to 50%.
I would rate the pricing as eight out of ten, indicating it is a reasonable cost for the product.
Microsoft purposefully obfuscates this through marketing ploys to hide costs.
 

Valuable Features

Cortex XDR ensures comprehensive protection with AI-driven analytics, multi-layered threat detection, and seamless integration, enhancing security management.
Microsoft Defender XDR integrates tools for comprehensive security, offering threat detection, automation, identity protection, and enhanced efficiency.
It incorporates AI for normal behavior detection, distinguishing unusual operations.
The product provides automation responses in case of a threat attack, severity assessments, centralized manageability, and comprehensive compliance features, resulting in reduced costs.
If a user doesn't click any link within 30 days and on the 31st day clicks a new link, Cortex XDR immediately alerts us that this user has clicked on an uncommon link or their behavior is uncommon.
With Microsoft threat intelligence information, it detects various types of threats, including insider attacks, malicious content, and data exfiltration.
This allows us to secure our systems in advance and proactively improve security, rather than waiting for incidents to occur.
Once we have it on the security dashboard, we can see a real-time storyline.
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Ranking in Extended Detection and Response (XDR)
7th
Average Rating
8.4
Reviews Sentiment
7.4
Number of Reviews
91
Ranking in other categories
Endpoint Protection Platform (EPP) (5th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (4th)
Microsoft Defender XDR
Ranking in Extended Detection and Response (XDR)
2nd
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
102
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Microsoft Security Suite (5th)
 

Mindshare comparison

As of September 2025, in the Extended Detection and Response (XDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 5.5%, down from 5.7% compared to the previous year. The mindshare of Microsoft Defender XDR is 6.1%, down from 8.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Extended Detection and Response (XDR) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender XDR6.1%
Cortex XDR by Palo Alto Networks5.5%
Other88.4%
Extended Detection and Response (XDR)
 

Featured Reviews

NiteshSharma - PeerSpot reviewer
Automated threat response and behavioral control improve security measures
I recommend adding a data loss prevention (DLP) solution to Cortex XDR by Palo Alto Networks. The inclusion of this feature would allow the application of DLP policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products. Additionally, multi-tenancy and multi-cloud features are not available and should be considered for inclusion.
MohtesanShaikh - PeerSpot reviewer
Experience improves security management and simplifies threat protection
I have created automated investigations, and while they work, they operate rather slowly in the Microsoft portal. If I automate something, it takes considerable time; if I do it manually, I can complete it in a quarter of the time. The automation response being slow is the main concern; when an incident occurs or if I run a remediation, it takes significant time to complete the remediation. There are some limitations regarding the scalability of Microsoft Defender XDR with specific licensing. For SMB customers, there is only Microsoft Defender for Business, and if they want more features such as XDR features and automation investigation or incident response, they need to purchase Defender for Endpoint. We are currently using the EDR.
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Use our free recommendation engine to learn which Extended Detection and Response (XDR) solutions are best for your needs.
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Top Industries

By visitors reading reviews
Computer Software Company
13%
Financial Services Firm
9%
Manufacturing Company
8%
Government
7%
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business41
Midsize Enterprise18
Large Enterprise35
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise23
Large Enterprise37
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. The ability to reverse damage caused by ransomware with minimal interruptions to...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions that are very scalable, secure, and user-friendly. Cortex XDR by Palo Alto offers ...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
What do you like most about Microsoft 365 Defender?
Microsoft Defender XDR provides strong identity protection with comprehensive insights into risky user behavior and potential indicators of compromise.
What is your experience regarding pricing and costs for Microsoft 365 Defender?
The pricing for Microsoft Sentinel operates on a pay-as-you-go model based on data ingestion. I recall that Defender XDR pricing is based on the number of endpoints.
What needs improvement with Microsoft 365 Defender?
For Microsoft Defender XDR ( /categories/extended-detection-and-response-xdr ), there is currently no ability to reset passwords for on-premises accounts, which is a key challenge. Incident managem...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about Cortex XDR by Palo Alto Networks vs. Microsoft Defender XDR and other solutions. Updated: August 2025.
867,349 professionals have used our research since 2012.