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Cisco SecureX [EOL] vs Microsoft Defender XDR comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jul 27, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco SecureX [EOL]
Average Rating
9.0
Reviews Sentiment
8.2
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Defender XDR
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
102
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (2nd), Microsoft Security Suite (4th)
 

Featured Reviews

Dene Lewis - PeerSpot reviewer
A scalable SaaS based platform that helps with cyber threat intelligence and automated hunting
I would rate Cisco SecureX a ten out of ten. I find the product to be a fantastic platform. If you are eligible, start using it straight away. The best way to evaluate it is to start using it and see where it fits within your organization. I think it helps our customers really deliver their SecOps goals, and I see it as a core foundation of CAE's own security strategy going forward. Our partnership with Cisco is one that was built on trust over a long period of time. This has enabled us to work together to be able to provide the solutions that our customers need to drive their organizations forward. The value we add as a reseller is being able to work closer with our customers, understand them, and get intimate with their organizations. That enables us to offer them the right solutions that will help them achieve their goals.
MohtesanShaikh - PeerSpot reviewer
Experience improves security management and simplifies threat protection
I have created automated investigations, and while they work, they operate rather slowly in the Microsoft portal. If I automate something, it takes considerable time; if I do it manually, I can complete it in a quarter of the time. The automation response being slow is the main concern; when an incident occurs or if I run a remediation, it takes significant time to complete the remediation. There are some limitations regarding the scalability of Microsoft Defender XDR with specific licensing. For SMB customers, there is only Microsoft Defender for Business, and if they want more features such as XDR features and automation investigation or incident response, they need to purchase Defender for Endpoint. We are currently using the EDR.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most beneficial feature of Cisco SecureX for cybersecurity efforts is its integration with other Cisco solutions and the environment. This sets it apart, as its APIs and overall integration capabilities are very strong. Additionally, its detection capabilities are commendable."
"SecureX takes all the separate pieces of security within your company, adds in intelligence from different sites and services on the internet, and makes them work together."
"The most valuable feature is its ability to manage all the applications and visibility. For example, if there is malware, spam, or another component that wants to attack the company in my servers, network, or applications, then SecureX will react to the problem."
"I like that I don't have to jump around to five different products and log into five different places to view the data that it returns."
"Integrates well with our existing security infrastructure."
"Using SecureX, a tool provided by Cisco, we can easily integrate it with many of our other Cisco products such as Cisco ISE and many networking devices."
"One of the most valuable features is the simplicity of deploying SecureX. It's very easy to do that and then you gain very detailed visibility into everything that's going on in your network and, obviously, at the device level. There's just a wealth of information that you can pull from all of these products that are part of SecureX. You know exactly if you have an issue or not."
"The automation and orchestration tools are the most valuable features."
"The advantage of Microsoft Defender XDR has over other XDRs in the market is that it's easy to use. You can quickly differentiate between alerts, incidents, devices, software, etc. It's easier to investigate an incident, and you have so many options. You can automate investigations and use playbooks. There's also the live response session, which is something you can't find in any other XDR."
"For me, the advanced hunting capabilities have been really great. It allowed querying the dataset with their own language, which is KQL or Kusto Query Language. That has allowed me to get much more insight into the events that have occurred. The whole power of 365 Defender is that you can get the whole story. It allows you to query an email-based activity and then correlate it with an endpoint-based activity."
"It's a very scalable tool that can be used in a very small environment or in a very large environment. Everything can be managed from a simple dashboard and can be scaled up or down depending on the customer's environment."
"The Email Explorer feature has proven invaluable, offering a broader perspective than automated alerts and incidents alone."
"What I like most about the product is its all-in-one solution. With Microsoft Defender XDR, we get coverage for various aspects like endpoint security, cloud security, and image-related cases, all within a single platform. This eliminates the need for multiple products or technical controls to address incidents. The main benefit became evident immediately after deployment, especially in its ability to analyze files and phishing emails quickly. By submitting suspicious files or emails, we receive quick results on whether they are legitimate, suspicious, or malicious, saving time."
"It reduces the risk of users accidentally clicking on phishing emails."
"On the Windows side, Microsoft Defender XDR is definitely integrated into the operating system. Once we have it on the security dashboard, we can see a real-time storyline."
"The most valuable features of Microsoft 365 Defender are the combination of all the capabilities and centralized management."
 

Cons

"They could put in more third-party [integrations]... also more playbooks, out-of-the-box, for automation [would be helpful]."
"One of the improvements the product needs is more integration with collaboration platforms."
"The playbooks provided with the product are great, although I would appreciate having more playbooks available. Threats are constantly evolving, so having access to updated playbooks is crucial."
"I would like it to integrate with another solution, e.g., DNA. I would like it to connect to that solution, but not the security aspect."
"If they could make the Cisco Umbrella piece a little bit more advanced or easier to manage, that would help. We use it for filtering and when you compare it to a normal content filter, it lacks some functionality."
"For us, the biggest sticking point is that the product is not being designed for multi-tenancy use at present, from an MSP perspective."
"Enhancing automation capabilities could further improve the product."
"I'm not sure that I would call it a bug, but sometimes the solution is a little slow."
"At times, when we have an incident email and we click on the link for that incident, it opens a pop-up, but there is nothing. It has happened a couple of times."
"The customer support aspect can be better because it's the biggest complaint I hear about Microsoft. They can improve the ease of support and licensing processes."
"Since all of our databases are updated and located in the cloud, I would like additional support for this."
"The AI could be improved. As an analyst, I want to be able to interact more with AI. The AI simply sends summaries. I can't ask it, for example, if it has seen any suspicious activity with device two. I have to go and check device two for myself."
"This solution could be improved if it included features such as those offered by Malwarebytes."
"I would like more of the features in Defender for 365 to be included in the smaller licenses. Even if I buy a small license and don't need everything, security shouldn't be a question. Security is one of the main aspects of all projects from our side, so it would be nice to have more features in the smaller licenses."
"Microsoft Defender XDR could be improved with a lower price."
"Just like in any solution, the price can always be cheaper."
 

Pricing and Cost Advice

"The pricing is competitive, especially for education institutions. Licensing can be a little bit difficult to navigate, especially with resellers with Cisco, but for us it has been pretty easy."
"You can spend less money for another solution, but if you really want to have a good solution you have to pay. We are happy that we are getting such a good solution for what we are spending."
"It is free. It can't get any better than that."
"The product is absolutely free to any customer. As such, the only thing one must keep in mind is that as long as he already has one Cisco security product, irregardless of what that product is, SecureX is available for free."
"The pricing is the best part of this solution. It is free if you buy Umbrella or Duo Security. It is also a good solution."
"It comes free with all Cisco products. So, it is a good price."
"It would be nice if they had a different pricing model. Most of our budget for projects goes towards Cisco."
"Cisco SecureX is more expensive than Trend Micro. However, considering the integration capabilities with other solutions and the quality of technical support, I believe there's justification for the price difference."
"I find the pricing to be quite competitive, especially considering its inclusion in our E5 subscription, which provides a comprehensive set of functionalities."
"Microsoft purposely makes its license combinations complex and includes combinations like Microsoft 365 E3 and Microsoft 365 E5, Office 365 E3, Office 365 E5, and Office 365 E1, so you get confused. Microsoft tries to sell you a bundle of a lot of things together."
"It is fairly priced because we get complete integrated services with the E5 license."
"The functionality is fantastic, but for medium and small-sized companies it's overpriced. It would be better if it were a little bit cheaper."
"The price could be better. Normally, the costs depend on the country you're located in for the license. When we were in the initial stage, we went with the E5 license they call premium standard. It cost us around $5.20 per month for four users."
"Sometimes 365 Defender is expensive, but it can be moderate, depending on the organization's size and the license type. We're satisfied with the cost because it gives us a product that protects our entire environment with DLP. To compromise some cost, of course, we are to complete the most secure environment."
"Microsoft Defender XDR is expensive."
"Purchasing Microsoft Defender XDR as part of a Microsoft 365 bundle can be cost-effective, but acquiring it as a standalone product may be more expensive."
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Top Industries

By visitors reading reviews
Computer Software Company
31%
Manufacturing Company
8%
Comms Service Provider
6%
Educational Organization
6%
Computer Software Company
16%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise7
Large Enterprise3
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise23
Large Enterprise37
 

Questions from the Community

Ask a question
Earn 20 points
What do you like most about Microsoft 365 Defender?
Microsoft Defender XDR provides strong identity protection with comprehensive insights into risky user behavior and potential indicators of compromise.
What is your experience regarding pricing and costs for Microsoft 365 Defender?
The pricing for Microsoft Sentinel operates on a pay-as-you-go model based on data ingestion. I recall that Defender XDR pricing is based on the number of endpoints.
What needs improvement with Microsoft 365 Defender?
I have created automated investigations, and while they work, they operate rather slowly in the Microsoft portal. If I automate something, it takes considerable time; if I do it manually, I can com...
 

Also Known As

Kenna.AppSec, Kenna.VI
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

NHS, Rackspace, UNC Pembroke, University of North Carolina at Charlotte, Missing Piece
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about CrowdStrike, Microsoft, SentinelOne and others in Extended Detection and Response (XDR). Updated: September 2025.
869,952 professionals have used our research since 2012.