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Cisco Secure Workload vs Microsoft Defender for Cloud comparison

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Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Cloud Workload Protection Platforms (CWPP)
8th
Average Rating
8.6
Reviews Sentiment
7.1
Number of Reviews
46
Ranking in other categories
Vulnerability Management (10th), Container Security (11th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (2nd), Cloud-Native Application Protection Platforms (CNAPP) (7th)
Cisco Secure Workload
Ranking in Cloud Workload Protection Platforms (CWPP)
18th
Average Rating
8.6
Reviews Sentiment
7.7
Number of Reviews
15
Ranking in other categories
Cloud and Data Center Security (8th), Microsegmentation Software (4th), Cisco Security Portfolio (8th)
Microsoft Defender for Cloud
Ranking in Cloud Workload Protection Platforms (CWPP)
1st
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Vulnerability Management (6th), Container Management (6th), Container Security (4th), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (7th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
 

Mindshare comparison

As of September 2026, in the Cloud Workload Protection Platforms (CWPP) category, the mindshare of Qualys TotalCloud is 1.8%, up from 1.4% compared to the previous year. The mindshare of Cisco Secure Workload is 2.0%, down from 2.7% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 10.7%, down from 14.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Cloud Workload Protection Platforms (CWPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Cloud10.7%
Qualys TotalCloud1.8%
Cisco Secure Workload2.0%
Other85.5%
Cloud Workload Protection Platforms (CWPP)
 

Featured Reviews

reviewer2859021 - PeerSpot reviewer
Sr Security Engineer at a tech vendor with 5,001-10,000 employees
Risk-based triage has transformed container security and now prioritizes high-impact threats
The best features Qualys TotalCloud offers currently include managing cloud infrastructure and container security while facing major challenges such as alert fatigue. Traditional vulnerability scanners flag hundreds of CVEs on short-lived Kubernetes containers, some of which have no internet exposure or are gone before we can even triage them. I leverage Qualys TotalCloud to move beyond static CVSS. I use it to implement runtime exposure, correlation risk reprioritization, and shift-left integration. This notifies developers to fix a base image upstream rather than patching live ephemeral instances. In my work with cloud and container security, the biggest operational hurdle was alert fatigue. I use Qualys to shift left from static CVSS severity to context-aware risk prioritization. I correlated raw vulnerability data with real-time risk factors such as public network exposure, active runtime execution, or overly permissive IAM roles. This allows us to immediately drop the priority of isolated containers and escalate lower-severity CVEs that sit on an exposed, high-risk path. We can map these findings directly back to our CI/CD pipelines so developers can patch the root base images upstream. We have drastically cut down the signal-to-noise ratio, saved a lot of manual hours doing triage work, and ensured engineering effort goes directly towards high-impact risk reduction.
Raj Metkar - PeerSpot reviewer
Director, Head of Networks at MUFG, EMEA
Discover internal application dependencies and create a dependency map
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration allows Cisco Secure Workload to learn about our networks and network tags, providing valuable insights into vulnerabilities related to the operating system and various applications installed on our servers. Recently, Cisco announced a new product called HyperShield, an AI-based autonomous micro-segmentation solution. While Cisco has not stated that HyperShield will replace Cisco Secure Workload, it represents a natural evolution for the company. HyperShield features dynamic policy discovery and enforcement; however, once policies are enforced, they do not change until a discovery occurs, requiring a re-enforcement process. This new platform operates autonomously, minimizing the need for user or security engineer intervention. I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product. Instead of enhancing the current product, they have introduced a new solution. Cisco plans to honor existing Tetration licenses, allowing users to transition to HyperShield without additional costs, reflecting the investment enterprises have already made. From Cisco’s perspective, this represents a natural progression in their product line. While the product name changes, it seems more of a rebranding effort. The enhancements are greater autonomy, improved discovery, and automatic enforcement, which are now being introduced in HyperShield. Cisco Secure Workload offers automatic policy enforcement but cannot adjust policies dynamically as the application needs to change. Having used the platform for the past five years, the recent announcement has been reassuring. Cisco has confirmed that our investment in the platform will not go to waste. They will honor our existing licenses, providing a natural migration path to the new solution without any disruption
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I depend heavily on the reports that I have from this tool."
"I found the initial setup user-friendly."
"If someone were to ask me to review Qualys TotalCloud, I would summarize it as an end-to-end solution for cloud security with visibility and governance-grade controls without needing to manage multiple disconnected tools."
"I highly recommend Qualys TotalCloud to other users."
"The most valuable feature is extensibility."
"Its excellent graphical interface makes the scanning process simple."
"Qualys TotalCloud provides a single, prioritized view of risk, reducing the workload associated with consolidating multiple sources for risk prioritization."
"Qualys TotalCloud has helped us view our risk structure, vulnerabilities, and security posture."
"The only use case I can see that makes sense is micro-segmentation. I think there are other use cases for it. The main purpose of the product is to do micro-segmentation by collecting IP. That could be done by installing an agent, and then you have all the communication coming in and out. You could also use some flow sensors installed in the network that receive a copy of the traffic and then report that back to the system."
"The most valuable feature of this solution is security."
"This product does everything that you need it to do and more and does a lot to provide visibility in a network environment, save time and money, and make the organization IT operate in a much more streamlined fashion."
"By using Tetration insight, we are able to get the latency on our level accounts and we can determine whatever the issue is with the application latency itself."
"It's stable."
"The product provides multiple-device integration."
"Scalability is its most valuable feature."
"Secure Workload's best feature is that it's an end-to-end offering from Cisco."
"The solution helped out management a lot, reducing about 50% of the time needed to spend on this after implementation and saving the organization money by consolidating into one solution instead of two or three."
"The most valuable feature is that it's intuitive. It's very intuitive."
"The integration with Logic Apps allows for automated responses to incidents."
"I would rate Microsoft Defender for Cloud a nine out of 10."
"It helps you to identify the gaps in your solution and remediate them, and it produces a compliance checklist against known standards such as ISO 27001, HIPAA, iTrust, etc."
"The features that Azure Security Center provides from a security point of view are amazing."
"Defender helps us evaluate our security posture and make it more secure by providing a wider overview of endpoint security and anti-malware technology."
"Azure Security Center helped us in recovering from our mistake."
 

Cons

"Regarding technical support from Qualys, they respond, but the response time can be too long. Sometimes we need to wait weeks for solutions to simple questions."
"In terms of improvement, remediation still belongs to the cloud team, which is one of the issues we faced with Qualys TotalCloud."
"There is room for improvement in the support."
"Qualys TotalCloud's increasing complexity, due to the development and deployment of multiple solutions, is making the GUI difficult to navigate."
"We would like to see Windows-based sensors available in Qualys, as this would make the platform more versatile and support a broader range of environments."
"To improve the user experience, reporting could be simplified for better comprehension by end users and project managers, facilitating issue resolution."
"The cost of Qualys TotalCloud is high and could be more competitive."
"The downside is only in container security, but it has not been a long time since they introduced these models."
"There is some overlap between Cisco Tetration and AppDynamics and there are few DC tools, it would be great to have a single pane of glass, rather than have to jump between different tools."
"Cisco Tetration needs more flags and system alerts that we should get with network capture."
"There was a controversy when Cisco reduced the amount of data they kept, and the solution became quite cost-intensive, which made its adoption challenging….Although they have modified it now, I preferred the previous version, and I wish all the functionality were back under the same product."
"The product must be integrated with the cloud."
"The multi-tenancy, redundancy, backup and restore functionalities, as well as the monitoring aspects of the solution, need improvement. The solution offers virtually no enterprise-grade possibility for monitoring."
"There's room for improvement when it comes to Cisco Secure Workload. A couple of internal areas could be refined a little bit. They are trying to solve it, depending on where you suppose the agent is. Suppose you have the agent on both the server and the client, which could be the front-end server or web server connecting to the. In that case, if those two are communicating on RPC, the server can look into its configuration. It could go down and find the configuration file on the FTP server and then set the policies to it. But there are a lot of different FTP servers out there. It's also a complex case for the tool to support all FTP servers."
"It is highly scalable, but there is a limitation that it is only available on Cisco devices."
"The entire interface could be improved; it's ugly and uninviting, and Tetration tends to be a lot more cumbersome and not very intuitive compared to the biggest competitor's modern-looking GUI."
"I would like to see better automation when it comes to pushing out security features to the recommendations, and better documentation on the step-by-step procedures for enabling certain features."
"They could always work to make the pricing a bit lower."
"Customer service and support from Microsoft are very poor. Even for high-severity cases, response or resolution time can extend to three or four weeks."
"We would like to have better transparency as to how the security score is calculated because as it is now, it is difficult to understand."
"To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an ingestion cost perspective."
"Early on, the lack of transparency is a challenge. Microsoft does not tell you the cost when they launch something."
"It's very expensive in terms of the need to maintain it actively."
"Agent features need to be improved. Sometimes, we are not able to get correct signals from the machines on which we have installed these agents."
 

Pricing and Cost Advice

"Qualys TotalCloud offers cost-effective licensing flexibility."
"The pricing is comparable. It is built into our other product, so I cannot piecemeal it. It is a part of our subscription."
"It isn't cheap, but it's reasonable. It helps us to manage things with very few resources."
"Although Qualys TotalCloud is relatively expensive due to its unique automation features, its cost-effectiveness is rated an eight out of ten, with ten being the most costly."
"Qualys TotalCloud is expensive."
"Qualys TotalCloud offers good pricing that is affordable and competitive with the market. Our partnership also provides us with additional benefits."
"The cost is high, but it meets our organizational needs."
"Qualys TotalCloud is expensive, but it offers a premier solution with no headaches."
"The price is outrageous. If you have money to throw at the product, then do it."
"The cost for the hardware is around 300k."
"Regarding price, Cisco Secure Workload can be expensive if you don't have a budget. If you're not doing micro-segmentation, every extra security measure or enforcement you're putting on top of your existing environment will be an extra cost. It's not a cheap solution at all. But from my point of view, if you need to do micro-segmentation, this is one of the best tools I've seen for it. I can't compare that to Microsoft's solution because I haven't looked into it. I've looked into VMware and Cisco. Those are the only two that I know of. I didn't know that Microsoft could do micro-segmentation at all. Maybe they can, but I haven't heard anything about it."
"The pricing is a bit higher than we anticipated."
"It is not cheap and pricing may limit scalability."
"The price is based on how many computers you're going to install it on."
"Pricing depends on the scope of the application and the features. Larger installations save more."
"I am not involved in this area. However, I believe its price is okay because even small customers are using Azure Security Center. I don't think it is very expensive."
"There is a helpful cost-reducing option that allows you to integrate production subscriptions with non-production subscriptions."
"Currently, Microsoft offers only one plan at the enterprise level which is $15 per machine."
"There are improvements that have to be made to the licensing. Currently, for servers, it has to be done by grouping the servers on a single subscription... We don't have an option whereby, if all those resources are in one subscription, we can have each of the individual servers subject to different planning."
"It has global licensing. It comes with multiple licenses since there are around 50,000 people (in our organization) who look at it."
"The cost is fair. There aren't any costs in addition to the standard licensing fee."
"While we pay for any additional features, the pricing seems competitive, though I am not involved in the specific cost details."
"The pricing model for most plans is generally good, but the cost of the new Defender for Storage plan is high and should be revisited, as it could lead to disabling desirable security features due to cost."
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Top Industries

By visitors reading reviews
Comms Service Provider
16%
Outsourcing Company
12%
Manufacturing Company
11%
Financial Services Firm
10%
Manufacturing Company
13%
Financial Services Firm
9%
Government
8%
Outsourcing Company
8%
Financial Services Firm
11%
Computer Software Company
10%
Manufacturing Company
8%
Outsourcing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business14
Midsize Enterprise6
Large Enterprise34
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise3
Large Enterprise8
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
In terms of improvement, remediation still belongs to the cloud team, which is one of the issues we faced with Qualys...
What is your primary use case for Qualys TotalCloud?
My main use case for Qualys TotalCloud is regarding the cloud visibility that we were not having previously. Previous...
What is your experience regarding pricing and costs for Cisco Secure Workload?
CloudStrike offers antivirus capabilities and firewall features for servers and VDI but lacks automatic policy discov...
What needs improvement with Cisco Secure Workload?
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration a...
What is your primary use case for Cisco Secure Workload?
When we onboarded Cisco Secure Workload, the usual use case was to discover internal application dependencies and cre...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
 

Also Known As

Qualys TotalCloud with FlexScan
Cisco Tetration
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
ADP, University of North Carolina Charlotte (UNCC)
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Find out what your peers are saying about Cisco Secure Workload vs. Microsoft Defender for Cloud and other solutions. Updated: September 2026.
914,262 professionals have used our research since 2012.