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Nyotron PARANOID vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 23, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Nyotron PARANOID
Ranking in Endpoint Protection Platform (EPP)
46th
Average Rating
8.6
Reviews Sentiment
7.0
Number of Reviews
2
Ranking in other categories
No ranking in other categories
ThreatLocker Zero Trust End...
Ranking in Endpoint Protection Platform (EPP)
7th
Average Rating
9.2
Reviews Sentiment
7.6
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Advanced Threat Protection (ATP) (6th), Application Control (1st), ZTNA (4th), Ransomware Protection (2nd)
 

Mindshare comparison

As of June 2025, in the Endpoint Protection Platform (EPP) category, the mindshare of Nyotron PARANOID is 0.1%, up from 0.1% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 0.8%, down from 0.8% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP)
 

Featured Reviews

Abel Browarnik - PeerSpot reviewer
A cost-effective security solution for endpoint protection
The initial setup is complex. It is rare to see an effective endpoint protection system that does not require some effort. It is neither on the cloud nor on-premises. You deploy it on every endpoint or server, irrespective of perimeter. You must use a deployment tool unless you prefer to do it manually on every endpoint or server. We used an automation tool to deploy it. Since we had MSI with us. We had to verify that everything worked, but it didn't take more than two weeks for 1000 endpoints.
Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"First of all, it does the job. It prevents harm to the operating system. Also, the visibility it gives to the user and to the administrator is very good."
"Nyotron protects your users and does not acquire any threat intelligence."
"The pre-built policies and the fact that I get notified when a user requests an application are significant."
"The solution has made knowing and managing what is running on our clients' devices much easier for us. We know they cannot run what they are not supposed to run."
"The unified alerts are useful."
"Being able to protect and trust nothing by default, known as zero trust, is the most important feature to me."
"Overall, I would rate ThreatLocker Zero Trust Endpoint Protection Platform a ten out of ten."
"What sets ThreatLocker apart from competitors offering similar solutions is ringfencing. The ringfencing controls, along with the application elevation features, keep it out of the user's line of sight while still protecting them."
"We use ThreatLocker's Allowlisting to whitelist specific applications and prevent unauthorized software from running."
"ThreatLocker Zero Trust Endpoint Protection Platform provides no-sweat security that we can easily deploy. We do not worry about our habitual clickers because we receive an alert if they try to do something, and we know ThreatLocker has already taken care of it."
 

Cons

"The main feature that is missing is to have the same solution on servers. Currently it's only protecting the client side, not the server. If they would add the server in the same solution, that would be great."
"The solution should be available on Linux and other platforms, including mobile platforms such as Android and iOS."
"It has not reduced helpdesk tickets. It has probably increased them by blocking applications and doing its job, resulting in people raising more tickets to know why they cannot use certain things."
"I cannot suggest anything that they are not already doing. They should keep adding features as they have been."
"It would be beneficial to have a tighter integration into PSA systems so that approvals can be done directly without having to leave the PSA."
"If you have a thousand computers with ThreatLocker agents on them, when you approve or create a new policy saying that Adobe Reader that matches this hashtag and meets certain criteria is allowed to be installed, it applies at the top level or the organization level. It applies to every computer in the company. When you make that new policy and push it out and it goes out and updates all of the clients. Unfortunately, at this time, it does not look like they stagger the push-out."
"The Cyber Hero certification exam could use a bit of love, but overall, I have been very satisfied with the platform."
"We also have customers who are frustrated because they cannot do what they used to do, which was run anything they wanted to."
"Initially, the learning curve was slightly high for me, however, that has been resolved now."
"Their product is solid. I have a hard time complaining much about it because when we do find little things, they are usually interface-related or related to things that would be nice to have."
 

Pricing and Cost Advice

Information not available
"I do not deal with pricing, but I assume it is cost-effective for us. We choose a solution based on functionality and affordability."
"I find ThreatLocker's pricing to be reasonable for the services it provides."
"We have not had any real issues with the pricing. As they have added more features, due to the way our contracts are structured with our customers, we have had to hold off on adopting the new features because they do add costs."
"The pricing is fair and there is no hard sell."
"Others say ThreatLocker is too expensive, and I tell them they're dreaming. It's well-priced for what it does."
"The pricing works fine for me. It's very reasonably priced."
"The price of ThreatLocker Allowlisting is reasonable in the market, but it is not fantastic."
"I can't complain. Cheaper would always be nice, but I think it's reasonable compared to other software in the cybersecurity market."
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Top Industries

By visitors reading reviews
No data available
Computer Software Company
35%
Retailer
8%
Manufacturing Company
5%
Financial Services Firm
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Nyotron PARANOID?
Nyotron protects your users and does not acquire any threat intelligence.
What needs improvement with Nyotron PARANOID?
There was an initial problem, we had to run the system in detection mode rather than prevention mode. The solution should be available on Linux and other platforms, including mobile platforms such ...
What is your primary use case for Nyotron PARANOID?
We use Nyotron PARANOID to protect endpoints. It serves as a second and last line of protection. It often detects threats that other endpoint protection systems such as Symantec, McAfee, Windows De...
What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...
 

Also Known As

No data available
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

El Al Airlines
Information Not Available
Find out what your peers are saying about Nyotron PARANOID vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: June 2025.
859,438 professionals have used our research since 2012.