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Nyotron PARANOID vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Oct 5, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Nyotron PARANOID
Ranking in Endpoint Protection Platform (EPP)
44th
Average Rating
8.6
Reviews Sentiment
7.0
Number of Reviews
2
Ranking in other categories
No ranking in other categories
ThreatLocker Zero Trust End...
Ranking in Endpoint Protection Platform (EPP)
7th
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
40
Ranking in other categories
Network Access Control (NAC) (5th), Advanced Threat Protection (ATP) (6th), Application Control (1st), ZTNA (4th), Ransomware Protection (1st)
 

Mindshare comparison

As of October 2025, in the Endpoint Protection Platform (EPP) category, the mindshare of Nyotron PARANOID is 0.2%, up from 0.1% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 0.9%, up from 0.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Market Share Distribution
ProductMarket Share (%)
ThreatLocker Zero Trust Endpoint Protection Platform0.9%
Nyotron PARANOID0.2%
Other98.9%
Endpoint Protection Platform (EPP)
 

Featured Reviews

Abel Browarnik - PeerSpot reviewer
A cost-effective security solution for endpoint protection
The initial setup is complex. It is rare to see an effective endpoint protection system that does not require some effort. It is neither on the cloud nor on-premises. You deploy it on every endpoint or server, irrespective of perimeter. You must use a deployment tool unless you prefer to do it manually on every endpoint or server. We used an automation tool to deploy it. Since we had MSI with us. We had to verify that everything worked, but it didn't take more than two weeks for 1000 endpoints.
Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"First of all, it does the job. It prevents harm to the operating system. Also, the visibility it gives to the user and to the administrator is very good."
"Nyotron protects your users and does not acquire any threat intelligence."
"The unified alerts are useful."
"The application whitelisting feature allows us to block and manage approved applications effectively. It ensures that no one can install an application on our systems unless it is approved by me, which is very efficient."
"Being able to protect and trust nothing by default, known as zero trust, is the most important feature to me."
"ThreatLocker provides visibility into user activity and application usage, empowering organizations to define acceptable applications and web browsers."
"The Zero Trust factor is valuable because it blocks everything. That helps us to stay ahead of bad actors. We do not have to be in recovery mode."
"The biggest improvement has been knowing that something unauthorized isn't going to get installed on anyone’s machines."
"The time saved from dealing with ransomware nonsense is invaluable."
"ThreatLocker’s support has been second to none."
 

Cons

"The main feature that is missing is to have the same solution on servers. Currently it's only protecting the client side, not the server. If they would add the server in the same solution, that would be great."
"The solution should be available on Linux and other platforms, including mobile platforms such as Android and iOS."
"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."
"The reporting could be improved."
"The user experience could be improved. Most complaints we get are based on users wanting certain functionality."
"One of the things I would really like is the ability to create custom groups and assign machines to them."
"I have no complaints, but a little bit more Mac support would be great."
"ThreatLocker could offer more flexible training, like online or offline classes after hours. The fact that they even provide weekly training makes it seem silly to suggest, but some people can't do it during the day, so they want to train after work. They could also start a podcast about issues they see frequently and what requires attention. A podcast would be helpful to keep us all apprised about what's going on and/or offline training for those people who can't train during the week."
"I cannot suggest anything that they are not already doing. They should keep adding features as they have been."
"The support could be quicker. There are times when there is a delay in getting a response. This is problematic when immediate attention is needed."
 

Pricing and Cost Advice

Information not available
"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."
"The pricing is pretty fair, considering other solutions. Licensing-wise, it did not take long."
"We have not had any real issues with the pricing. As they have added more features, due to the way our contracts are structured with our customers, we have had to hold off on adopting the new features because they do add costs."
"Considering what this product does, ThreatLocker is very well-priced, if not too nicely priced for the customer."
"The price is very reasonable, and we have been able to integrate ThreatLocker with all of our clients."
"The pricing works fine for me. It's very reasonably priced."
"We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This was primarily a mistake on our part due to how we initially priced it to clients."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
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Top Industries

By visitors reading reviews
No data available
Computer Software Company
28%
Retailer
9%
Manufacturing Company
7%
Financial Services Firm
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
By reviewers
Company SizeCount
Small Business32
Midsize Enterprise4
Large Enterprise3
 

Questions from the Community

What do you like most about Nyotron PARANOID?
Nyotron protects your users and does not acquire any threat intelligence.
What needs improvement with Nyotron PARANOID?
There was an initial problem, we had to run the system in detection mode rather than prevention mode. The solution should be available on Linux and other platforms, including mobile platforms such ...
What is your primary use case for Nyotron PARANOID?
We use Nyotron PARANOID to protect endpoints. It serves as a second and last line of protection. It often detects threats that other endpoint protection systems such as Symantec, McAfee, Windows De...
What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Pricing, setup costs, and licensing have been pretty accessible and manageable. It was not too expensive to get started, especially at a small scale for a smaller MSP. It is very accessible, easy t...
What needs improvement with ThreatLocker Allowlisting?
For the space that it's in, it's already there. I don't know of another product that compares to its level. Even recently, with the addition of the detect module is a very nice add-on to the packet...
 

Also Known As

No data available
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

El Al Airlines
Information Not Available
Find out what your peers are saying about Nyotron PARANOID vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: September 2025.
869,760 professionals have used our research since 2012.