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Cisco SecureX [EOL] vs Microsoft Defender XDR comparison

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Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
108
Ranking in other categories
Endpoint Protection Platform (EPP) (5th), Endpoint Detection and Response (EDR) (7th), Extended Detection and Response (XDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (2nd)
Cisco SecureX [EOL]
Average Rating
9.0
Reviews Sentiment
8.2
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Defender XDR
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
107
Ranking in other categories
Endpoint Detection and Response (EDR) (8th), Extended Detection and Response (XDR) (4th), Microsoft Security Suite (4th)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Dene Lewis - PeerSpot reviewer
Head of Technical Strategy and Direction CAE Technology Services Ltd at CAE Technology Services Limited
A scalable SaaS based platform that helps with cyber threat intelligence and automated hunting
I would rate Cisco SecureX a ten out of ten. I find the product to be a fantastic platform. If you are eligible, start using it straight away. The best way to evaluate it is to start using it and see where it fits within your organization. I think it helps our customers really deliver their SecOps goals, and I see it as a core foundation of CAE's own security strategy going forward. Our partnership with Cisco is one that was built on trust over a long period of time. This has enabled us to work together to be able to provide the solutions that our customers need to drive their organizations forward. The value we add as a reseller is being able to work closer with our customers, understand them, and get intimate with their organizations. That enables us to offer them the right solutions that will help them achieve their goals.
KO
House security operator at Cypress Creek Renewables
Advanced threat hunting saves significant time in tracking and responding to incidents
Microsoft Defender XDR could be improved with a lower price. My main suggestion would essentially be what Copilot is providing, which is a single pane of glass, so I don't have to go to different windows. That's just a workflow consideration for me. It would be great to have all the information centralized into one particular data app. If I need to open up extra ones, I can, however, I would appreciate a future where everything I need is right there on one single pane of glass. Beyond that, there's really nothing else I see that I would want Microsoft to improve.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It is easy to use."
"The integrations are out-of-the-box, as are the playbooks."
"Cortex Xnor's playbooks predefine the workflow of the automation, such as response processes, alert triggering, and enriching the context, collecting relevant indicators such as hashes, IP addresses, or domains efficiently and can detect and block malicious attacks with firewalls."
"Cortex XDR by Palo Alto Networks is easy to use and does not consume a lot of hardware resources."
"The solution helps find bugs, and it is safe to use to prevent attacks by hackers."
"The most valuable feature of Cortex XDR by Palo Alto Networks is the low consumption of system resources. The solution uses a lot of AI and machine learning."
"Monitoring is most valuable."
"The most valuable aspect of Cortex XDR by Palo Alto Networks for me is its integration with AI detection, where we get to know the behavioral detection based on users, traffic patterns, and different services that we consume."
"The automation and orchestration tools are the most valuable features."
"I like that I don't have to jump around to five different products and log into five different places to view the data that it returns."
"The most beneficial feature of Cisco SecureX for cybersecurity efforts is its integration with other Cisco solutions and the environment. This sets it apart, as its APIs and overall integration capabilities are very strong. Additionally, its detection capabilities are commendable."
"The forensics are amazing because when you have enrichment, and the solutions talk with each other, when you need it, you have the ability to know everything in the organization: when, why, whatever."
"It has evolved a lot, just that monitoring piece to the current Orchestrator piece. The additional analytics are there. They now have something called Insight, which can basically take data from Microsoft Azure AD and Intune to give us information about our endpoints. This is detailed information about the endpoints, from Secure Endpoint and all these different products. So, it is just constantly evolving. Every time that it evolves, we have more information with more visibility. There are more features that we have that just make everything so much easier, and it is in one place. I don't have to keep going back and forth. I don't have to go to Secure Endpoint and ISE to get the data. I don't have to go to Intune on Microsoft to get the information. It is all in one place."
"One of the most valuable features is the simplicity of deploying SecureX. It's very easy to do that and then you gain very detailed visibility into everything that's going on in your network and, obviously, at the device level. There's just a wealth of information that you can pull from all of these products that are part of SecureX. You know exactly if you have an issue or not."
"Our customers find the product's third-party integrations valuable. Our customers are also impressed with the tool's capability to pick up third-party threat feeds and use that as part of the decision-making process."
"SecureX enables us to have all the threat intelligence and threat event data in one place."
"The Email Explorer feature has proven invaluable, offering a broader perspective than automated alerts and incidents alone."
"The summarization of emails is a valuable feature."
"The email protection feature is the most valuable because our risks primarily lie there, and it seems to be the most popular target."
"In our company,we have faced multiple attacks over the last few months, but none of them have been successful, and I think Microsoft Defender XDR has played a major role in it."
"The product is very easy to use."
"Defender XDR has a feature called the timeline that lets you track all activities. It helps a lot with investigations."
"Vulnerability assessment and just-in-time access are some valuable features of Defender for server plans."
"Among the most valuable features are the alert timeline, the alert story, which is pretty detailed. It gives us complete insight into what exactly happened on the endpoint. It doesn't just say, "Malware detected." It tells us what caused that malware to be detected and how it was detected. It gives us a complete timeline from beginning to end."
 

Cons

"We had a problem with getting our older endpoints up to date, but their newest updates have been really good. I've been pleased with it in terms of what our needs are. It's doing what we want it to do."
"They've been having some issues with updating their endpoint agents, and it has been quite frustrating."
"In general, the price could be more competitive."
"The dashboard is the area that needs to improve so that we can have the ability to drill down without having to go elsewhere to verify results."
"We have found that there are times Cortex XDR by Palo Alto Networks does not detect some of the viruses, we have to use another protection solution called Kaspersky."
"It tends to do 99.9% of things. The only thing I'd like is single sign-on authentication into their cloud platform so that my users can be properly authenticated against it."
"There are a large number of false positives."
"It's very time-consuming to log support issues and the people that answer the tickets aren't very knowledgeable."
"The automation and orchestration could be simpler. It could be that all the other parts are that easy to use so that these stick out as a negative, but that's the trickiest part for us. The workflows within the orchestration are just a bit more difficult."
"I would like it to integrate with another solution, e.g., DNA. I would like it to connect to that solution, but not the security aspect."
"If they could make the Cisco Umbrella piece a little bit more advanced or easier to manage, that would help. We use it for filtering and when you compare it to a normal content filter, it lacks some functionality."
"Enhancing automation capabilities could further improve the product."
"I'm not sure that I would call it a bug, but sometimes the solution is a little slow."
"what's missing right now is the multi-tenant capability."
"For us, the biggest sticking point is that the product is not being designed for multi-tenancy use at present, from an MSP perspective."
"One of the improvements the product needs is more integration with collaboration platforms."
"The documentation on their website is somewhat outdated and doesn't show properly. I wanted to try a query in Microsoft Defender 365. When I opened the related documentation from the security blog on the Microsoft website, the figures were not showing. It was difficult to understand the article without having the figures. The figures were there in the article, but they were not getting loaded, which made the article obsolete."
"The only problem I find is that the use cases are built-in. There is no template available that you can modify according to your organization's standards. What they give is very generic, the market standard, but that might not be applicable to every organization."
"Some of our older hardware experienced a slight bump in CPU and memory usage. Although I don't have empirical data to back that up, I would suggest possibly more streamlining in the software."
"There are a few technical issues with Defender XDR that can be improved. Sometimes, the endpoint devices are not reporting properly to the Defender 365 portal. When you're getting all the information from the Microsoft portal, the devices are sometimes not in sync. We have hundreds of endpoint devices, some needing to be onboarded again."
"Generally, antivirus products provide a central control to manage every device in terms of who is installing it or who is trying to disable it, but Microsoft doesn't have such a control center for the antivirus product it provides."
"Since all of our databases are updated and located in the cloud, I would like additional support for this."
"Defender also lacks automated detection and response. You need to resolve issues manually. You can manage multiple Microsoft security products from a single portal, and all your security recommendations are in one place. It's easy to understand and manage. However, I wouldn't say Defender is a single pane of glass. You still need to switch between all of the available Microsoft tools. You can see all the alerts in one panel, but you can't automate remediation."
"A simple dashboard without having to use MS Sentinel would be a welcome improvement."
 

Pricing and Cost Advice

"Cortex XDR’s pricing is very reasonable."
"The pricing is a little high. It is per user per year."
"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"The solution is expensive. It's pricing is on a yearly-basis."
"The cost depends on your chosen license type, like Pro or other licenses."
"The pricing is okay, although direct support can be expensive."
"Our customers have expressed that the price is high."
"I am using the Community edition."
"It would be nice if they had a different pricing model. Most of our budget for projects goes towards Cisco."
"The product is absolutely free to any customer. As such, the only thing one must keep in mind is that as long as he already has one Cisco security product, irregardless of what that product is, SecureX is available for free."
"It comes free with all Cisco products. So, it is a good price."
"You can spend less money for another solution, but if you really want to have a good solution you have to pay. We are happy that we are getting such a good solution for what we are spending."
"The pricing is the best part of this solution. It is free if you buy Umbrella or Duo Security. It is also a good solution."
"The pricing is competitive, especially for education institutions. Licensing can be a little bit difficult to navigate, especially with resellers with Cisco, but for us it has been pretty easy."
"It is free. It can't get any better than that."
"Cisco SecureX is more expensive than Trend Micro. However, considering the integration capabilities with other solutions and the quality of technical support, I believe there's justification for the price difference."
"Understanding the subscription model has been a bit challenging, as every feature or requirement comes with an additional cost."
"Microsoft Defender XDR is already included in our Office 365 licensing. It is better because we're saving money by using it."
"Microsoft should provide lower-level licensing options. They should do it in such a way that even an individual could purchase a license, and it should be entirely flexible."
"Microsoft Defender XDR is included in our license."
"Sometimes 365 Defender is expensive, but it can be moderate, depending on the organization's size and the license type. We're satisfied with the cost because it gives us a product that protects our entire environment with DLP. To compromise some cost, of course, we are to complete the most secure environment."
"365 Defender can get expensive because you pay per gigabyte of data ingested. On the other hand, much of the data available in the other Microsoft security solutions are made available relatively cheaply—sometimes at cost or for free. Integrating only a limited set of third-party solutions with Sentinel would be cost-effective. It's much more affordable if companies only have Microsoft stuff."
"I believe that the pricing of the licensing is fair."
"I believe the pricing is fair and acceptable. I consider it to be reasonable and satisfactory."
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Top Industries

By visitors reading reviews
Computer Software Company
9%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Computer Software Company
19%
Marketing Services Firm
11%
Government
8%
Outsourcing Company
7%
Computer Software Company
12%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business44
Midsize Enterprise20
Large Enterprise47
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise7
Large Enterprise3
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise26
Large Enterprise39
 

Questions from the Community

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How is Cortex XDR compared with Microsoft Defender?
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What do you like most about Microsoft 365 Defender?
Microsoft Defender XDR provides strong identity protection with comprehensive insights into risky user behavior and p...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with pricing, setup, costs, and licensing of Microsoft Defender XDR is tied to our E5 subscription, whi...
What needs improvement with Microsoft 365 Defender?
I am not aware of a mobile app that would be available for my team. With a single analyst, if she is ever away, it wo...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Kenna.AppSec, Kenna.VI
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
NHS, Rackspace, UNC Pembroke, University of North Carolina at Charlotte, Missing Piece
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about CrowdStrike, SentinelOne, TrendAI and others in Extended Detection and Response (XDR). Updated: February 2026.
884,873 professionals have used our research since 2012.